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The map label for this gene is engD [H]

Identifier: 157825994

GI number: 157825994

Start: 854013

End: 855110

Strand: Reverse

Name: engD [H]

Synonym: A1C_04730

Alternate gene names: 157825994

Gene position: 855110-854013 (Counterclockwise)

Preceding gene: 157825995

Following gene: 157825993

Centisome position: 69.46

GC content: 35.7

Gene sequence:

>1098_bases
ATGATACTAAAACTAGGAATTGTTGGGTTGCCGAATGTTGGTAAGTCGACGTTATTTAATGCCTTAACGGCAAGTCAGGC
TGCGGATGCCGCTAATTATCCGTTTTGTACTATTGAGCCTAATAGCAGCAAAGTTTTAGTGCCTGATGAGCGTTTACAAC
GACTCGCAAGCTTAGCCGGAAGCGGAAAAATTATTCCGTCTTATATTGAGTTTGTCGATATTGCAGGACTTGTTGAAGGA
GCAAGCAAAGGGGAGGGGCTAGGTAATAAGTTTTTATCTCATATTAGGGAAGTCTCTGCAATACTGCACGTACTGCGTTG
CTTTGAAGATGAGGATATAACGCACGTACATAACAAAGTCGATCCAATCTATGACCTTGAGGTTATTGAAACAGAGTTAA
TACTTGCTGATATAGAATCGGTCGAAAAGCGTTTAGTAACAAGTGAAAAACGCTTAAAGTCAGGTGATAAAACAATGGTA
GAGCAAATAGAACTGTTAAAAGAGGTTTATAAAGTGCTAGCTAACGGTAAACCTGCAAGAGTGCTAAATGAAGTTTTAGG
ATCTGATAATTTAAAACAATTGCAGTTAATTACTTCTAAACCTGTTTTATATATATGTAACGTACTTGAAAAAGATGCAG
CTATAGGTAATGAATGTACAAAATTAGTAGCTGCAAGAGCAAAGAAAGAAAATGCTAGAAGCGTCGTAATTTCTTCAAAA
ATAGAAGCTGAGATTGCTTTACTTGAAAGCATTGAAGAAAAAGAAGAGTTTTTAAAATTTATAGGCTTAAATAAAACAGG
GCTTAGTAAAGTAATTAAAGAAGGGTATAATCTTTTAAATCTTAAAAGTTTTTTTACTATAGGTCCTAAAGAAGCTCATA
GTTGGACTTTTAAAGACGGCACGCTTGCACCGGCTGCTGCCGGTATTATTCATACCGATTTTGAAAAAGGCTTTATTAGA
GCAGAAGTTATCGGTTATGAAGATTATATAAACCTTGGTAGTGAAGCAAAAGCCAAGGAAGTAGGTAAAATGCGTTTAGA
GGGTAAAGAATATAAAATGCAGGATGGGGATATAGTACATTTTAGATTTAACGTTTAA

Upstream 100 bases:

>100_bases
TTTCAATCTAAACCTTTTTACGAGAAATTAGGATATAAGCTAGAATTTACAAGATACGGTTATACAAAAGATTCTATAAT
TATTGTTTACGGAAAGATTT

Downstream 100 bases:

>100_bases
ATACTTAAAGTATTAGGTTTTATTGTAGGATACAGAAAAGTGTTGCAATGTCATTCCAGCGTAGAGCATTGTTGCGTGGA
CCGGTTTATCCGTCATTGCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MILKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDERLQRLASLAGSGKIIPSYIEFVDIAGLVEG
ASKGEGLGNKFLSHIREVSAILHVLRCFEDEDITHVHNKVDPIYDLEVIETELILADIESVEKRLVTSEKRLKSGDKTMV
EQIELLKEVYKVLANGKPARVLNEVLGSDNLKQLQLITSKPVLYICNVLEKDAAIGNECTKLVAARAKKENARSVVISSK
IEAEIALLESIEEKEEFLKFIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIR
AEVIGYEDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV

Sequences:

>Translated_365_residues
MILKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDERLQRLASLAGSGKIIPSYIEFVDIAGLVEG
ASKGEGLGNKFLSHIREVSAILHVLRCFEDEDITHVHNKVDPIYDLEVIETELILADIESVEKRLVTSEKRLKSGDKTMV
EQIELLKEVYKVLANGKPARVLNEVLGSDNLKQLQLITSKPVLYICNVLEKDAAIGNECTKLVAARAKKENARSVVISSK
IEAEIALLESIEEKEEFLKFIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIR
AEVIGYEDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV
>Mature_365_residues
MILKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDERLQRLASLAGSGKIIPSYIEFVDIAGLVEG
ASKGEGLGNKFLSHIREVSAILHVLRCFEDEDITHVHNKVDPIYDLEVIETELILADIESVEKRLVTSEKRLKSGDKTMV
EQIELLKEVYKVLANGKPARVLNEVLGSDNLKQLQLITSKPVLYICNVLEKDAAIGNECTKLVAARAKKENARSVVISSK
IEAEIALLESIEEKEEFLKFIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIR
AEVIGYEDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=45.0402144772118, Blast_Score=298, Evalue=5e-81,
Organism=Homo sapiens, GI58761502, Length=223, Percent_Identity=37.6681614349776, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1787454, Length=368, Percent_Identity=50, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1789574, Length=187, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=44.0217391304348, Blast_Score=291, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=371, Percent_Identity=40.1617250673854, Blast_Score=253, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=382, Percent_Identity=38.7434554973822, Blast_Score=226, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=175, Percent_Identity=33.1428571428571, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=44.141689373297, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=44.141689373297, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=44.141689373297, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.5487804878049, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24585318, Length=143, Percent_Identity=31.4685314685315, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40247; Mature: 40247

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDERLQRLASLAG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHHHHCC
SGKIIPSYIEFVDIAGLVEGASKGEGLGNKFLSHIREVSAILHVLRCFEDEDITHVHNKV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPIYDLEVIETELILADIESVEKRLVTSEKRLKSGDKTMVEQIELLKEVYKVLANGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHH
VLNEVLGSDNLKQLQLITSKPVLYICNVLEKDAAIGNECTKLVAARAKKENARSVVISSK
HHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
IEAEIALLESIEEKEEFLKFIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHHEECCCCCCCCEECCCC
TLAPAAAGIIHTDFEKGFIRAEVIGYEDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVH
CCCHHHHHHEECCCCCCCEEEEEECHHHHHCCCCCHHHHHHHHHHCCCCCEECCCCCEEE
FRFNV
EEECC
>Mature Secondary Structure
MILKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDERLQRLASLAG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHHHHCC
SGKIIPSYIEFVDIAGLVEGASKGEGLGNKFLSHIREVSAILHVLRCFEDEDITHVHNKV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPIYDLEVIETELILADIESVEKRLVTSEKRLKSGDKTMVEQIELLKEVYKVLANGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHH
VLNEVLGSDNLKQLQLITSKPVLYICNVLEKDAAIGNECTKLVAARAKKENARSVVISSK
HHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
IEAEIALLESIEEKEEFLKFIGLNKTGLSKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHHEECCCCCCCCEECCCC
TLAPAAAGIIHTDFEKGFIRAEVIGYEDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVH
CCCHHHHHHEECCCCCCCEEEEEECHHHHHCCCCCHHHHHHHHHHCCCCCEECCCCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]