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The map label for this gene is ydhC [C]

Identifier: 157825993

GI number: 157825993

Start: 851757

End: 852980

Strand: Reverse

Name: ydhC [C]

Synonym: A1C_04715

Alternate gene names: 157825993

Gene position: 852980-851757 (Counterclockwise)

Preceding gene: 157825994

Following gene: 157825991

Centisome position: 69.29

GC content: 33.17

Gene sequence:

>1224_bases
ATGAAAATAATTGCTAAAATCCCGGCATGGATGCTTCTATGCTTATTTATTTTATCACCGACTACGGAAACAATTTATAC
TTCAGGATTACCGAGTTTAACTAAATATTTCGGCATTGACGGTGGTATCACTCAAACTACCTCTACATTATATTTTTTAG
GATTTGCTCTCGGTATATTAACGCTTGGCAGATTATCAGATATTTACGGCAGAAGACCTATAGTTTTACTTGGGCTTTTT
ATTTATGTTGTATCTTCAATTATTAGCATTTTTGCAGTTAATATAGAAATGCTGATGATAGCTCGTTTTGTACAAGCTTT
CGGTGTAAGTATAGGTTCTGTTATTGGGCAGGCCATGGCTAGAGATTCCTATCAGGGCTCAGAGTTATCATATGTCTATG
CTCGCTTATCTCCGTGTCTGTTATTTATCCCTTCTCTCGGTTCATCTATAGGTGGCTATATTATAGAATATTCAAGCTGG
CATTATGTTTTTGTATTTTTTAGTCTTACCGGTACTATATTACTAGCTTTATATTATAAAGTTTTACCTGAAACAAATTC
GTATATAGCTTTTTCACAAAGCAGTAAATATTTTGAGGTTTTACAGGTAATTATTAAAGATAAAATTCTTTTGTTATATG
CTTTTATCATCGGTGCATTTAACGGCATATATTATGGTTTTTTCATAGAAGCTCCTTTTATTTTTATTGATACAATGAAA
GTTTCGCCATCTTTTTACGGTAAATTAGTATTTTTGTTATCTTTTGCCGCTATCTTTGGAGGGTTTTTAGGAGAATATTT
AATAAAAAAACGCCATGTACACGATAAAAAAGTTATGGGTTTAGGATTTATATTTAGTCTATGTGGATGTATATTATTTG
CGGTAAATGCTTTTATATTGGAAGTTGTTTCAGCAAATCATAGTCTTGCAATCGCTACGGTATTTGCACCGATGATGATT
CATATGGTTGGGCATAATCTACTGATCCCTATGACGCTTCGTTATGCACTGGAGGATTATGCTAAAGTCACAGGTACGGC
AGGATCTATATTTGGTACGATATACTATGTAGTGATCGCTGCCGTAACTTATTTGGTTTCTAAAATACACAGCGAAACGA
TAAGCAATTTTGCTTTATTATGCTTCGTTTTAAGTATTAGCTCTGCTTCTGCATTTTACTGTATTGGGATTTTATATAAG
AAAAAGTCAGGTGTTCCTGATTAA

Upstream 100 bases:

>100_bases
TTGATTGAGAGAGTAGCAAAATTAAAAAACATTACGGAATGAATTTGTTTGGAGCGGATTAATCGATAAGACTCGATGAA
CCGAAATAAAAAAATCATTT

Downstream 100 bases:

>100_bases
AGATAGGAATCGTTATTATGAGCAGTTGTGGGAACCCGCGTGGCTCATTTTATGTCGTTACTGTGTGGGCGGTAATCTAG
CAAAACCTATAAAAAAGGTT

Product: bicyclomycin resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKIIAKIPAWMLLCLFILSPTTETIYTSGLPSLTKYFGIDGGITQTTSTLYFLGFALGILTLGRLSDIYGRRPIVLLGLF
IYVVSSIISIFAVNIEMLMIARFVQAFGVSIGSVIGQAMARDSYQGSELSYVYARLSPCLLFIPSLGSSIGGYIIEYSSW
HYVFVFFSLTGTILLALYYKVLPETNSYIAFSQSSKYFEVLQVIIKDKILLLYAFIIGAFNGIYYGFFIEAPFIFIDTMK
VSPSFYGKLVFLLSFAAIFGGFLGEYLIKKRHVHDKKVMGLGFIFSLCGCILFAVNAFILEVVSANHSLAIATVFAPMMI
HMVGHNLLIPMTLRYALEDYAKVTGTAGSIFGTIYYVVIAAVTYLVSKIHSETISNFALLCFVLSISSASAFYCIGILYK
KKSGVPD

Sequences:

>Translated_407_residues
MKIIAKIPAWMLLCLFILSPTTETIYTSGLPSLTKYFGIDGGITQTTSTLYFLGFALGILTLGRLSDIYGRRPIVLLGLF
IYVVSSIISIFAVNIEMLMIARFVQAFGVSIGSVIGQAMARDSYQGSELSYVYARLSPCLLFIPSLGSSIGGYIIEYSSW
HYVFVFFSLTGTILLALYYKVLPETNSYIAFSQSSKYFEVLQVIIKDKILLLYAFIIGAFNGIYYGFFIEAPFIFIDTMK
VSPSFYGKLVFLLSFAAIFGGFLGEYLIKKRHVHDKKVMGLGFIFSLCGCILFAVNAFILEVVSANHSLAIATVFAPMMI
HMVGHNLLIPMTLRYALEDYAKVTGTAGSIFGTIYYVVIAAVTYLVSKIHSETISNFALLCFVLSISSASAFYCIGILYK
KKSGVPD
>Mature_407_residues
MKIIAKIPAWMLLCLFILSPTTETIYTSGLPSLTKYFGIDGGITQTTSTLYFLGFALGILTLGRLSDIYGRRPIVLLGLF
IYVVSSIISIFAVNIEMLMIARFVQAFGVSIGSVIGQAMARDSYQGSELSYVYARLSPCLLFIPSLGSSIGGYIIEYSSW
HYVFVFFSLTGTILLALYYKVLPETNSYIAFSQSSKYFEVLQVIIKDKILLLYAFIIGAFNGIYYGFFIEAPFIFIDTMK
VSPSFYGKLVFLLSFAAIFGGFLGEYLIKKRHVHDKKVMGLGFIFSLCGCILFAVNAFILEVVSANHSLAIATVFAPMMI
HMVGHNLLIPMTLRYALEDYAKVTGTAGSIFGTIYYVVIAAVTYLVSKIHSETISNFALLCFVLSISSASAFYCIGILYK
KKSGVPD

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=307, Percent_Identity=24.4299674267101, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788509, Length=240, Percent_Identity=28.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787065, Length=244, Percent_Identity=27.0491803278689, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082312, Length=355, Percent_Identity=21.1267605633803, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790146, Length=191, Percent_Identity=25.130890052356, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324264, Length=172, Percent_Identity=29.0697674418605, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44952; Mature: 44952

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIAKIPAWMLLCLFILSPTTETIYTSGLPSLTKYFGIDGGITQTTSTLYFLGFALGIL
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TLGRLSDIYGRRPIVLLGLFIYVVSSIISIFAVNIEMLMIARFVQAFGVSIGSVIGQAMA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDSYQGSELSYVYARLSPCLLFIPSLGSSIGGYIIEYSSWHYVFVFFSLTGTILLALYYK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
VLPETNSYIAFSQSSKYFEVLQVIIKDKILLLYAFIIGAFNGIYYGFFIEAPFIFIDTMK
HCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEE
VSPSFYGKLVFLLSFAAIFGGFLGEYLIKKRHVHDKKVMGLGFIFSLCGCILFAVNAFIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVSANHSLAIATVFAPMMIHMVGHNLLIPMTLRYALEDYAKVTGTAGSIFGTIYYVVIA
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AVTYLVSKIHSETISNFALLCFVLSISSASAFYCIGILYKKKSGVPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIAKIPAWMLLCLFILSPTTETIYTSGLPSLTKYFGIDGGITQTTSTLYFLGFALGIL
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TLGRLSDIYGRRPIVLLGLFIYVVSSIISIFAVNIEMLMIARFVQAFGVSIGSVIGQAMA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDSYQGSELSYVYARLSPCLLFIPSLGSSIGGYIIEYSSWHYVFVFFSLTGTILLALYYK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
VLPETNSYIAFSQSSKYFEVLQVIIKDKILLLYAFIIGAFNGIYYGFFIEAPFIFIDTMK
HCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEE
VSPSFYGKLVFLLSFAAIFGGFLGEYLIKKRHVHDKKVMGLGFIFSLCGCILFAVNAFIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVSANHSLAIATVFAPMMIHMVGHNLLIPMTLRYALEDYAKVTGTAGSIFGTIYYVVIA
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AVTYLVSKIHSETISNFALLCFVLSISSASAFYCIGILYKKKSGVPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA