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The map label for this gene is dnaA [H]

Identifier: 157825988

GI number: 157825988

Start: 846716

End: 848107

Strand: Direct

Name: dnaA [H]

Synonym: A1C_04690

Alternate gene names: 157825988

Gene position: 846716-848107 (Clockwise)

Preceding gene: 157825987

Following gene: 157825992

Centisome position: 68.78

GC content: 34.7

Gene sequence:

>1392_bases
GTGAATACTAATCAAATAATTTTAACAGATCAAGGGGATAATTATGTAAATCTCTGGAGTCACGTGGCTCAAGATCTTTA
CAATCATTACGGTGAAACTCTATATAATAGCTGGTTTAGTAAAGTCAATTTTATAGAGTCTTCATTAAATACCGTTATTC
TTTGTGCTCCTACTAACTTTGTCAGAGATTGGATAAAATCCAAGTACTCTATGGTCATATTGCAACTATTTCAACATTAT
AACAATACCATTAAGTCGATTGACATAATTACTAAAGAGCTACCTGGAACAACCCAGACAGTTATAGAATTACCTACTAA
GACTTTTGCAGATATCGGCAGTAGTGAACTTAATTCGGAAAATATCTTTTCAACCCTTGATGTACGTTTTACTTTCGATA
ATTTTGTGGTTGGAGCCCCAAATGAGCTAGCTTATGCAGCAGCAAGGGCTGTTGCGGAATCATCAGGTGCAGTTTCTGAA
TCTAATCCGCTTTTTCTATATGGCGGGGTTGGACTCGGTAAGACGCATTTAATGCATGCAATCGGTTGGTACATCAAGCA
GAATAACCCAAGCCGCAAAGTAATATACATGTCGGCAGAAAAATTTATGTATCAGTTTGTTAAAGCTCTGCGTAACAAAG
AAGTAATCTTGTTTAAAGAGAAATTCCGCTCGGTTGACGTGTTGATGATTGATGATATTCAATTTATTTGCGGTAAAGAT
AGTACGCAGGAAGAATTTTTCCACACTTTTAATACATTGATTGATAATAACCGTCAAATGGTCATTTCTTGTGATAGGTC
ACCTTCAGATTTAGATAATATTGAAGATCGAATAAAATCTCGCCTTGGATGGGGCTTAGTTGCCGATGTTCATAGTACTA
CTTATGAACTGCGACTCGGTATTCTAGAATCTAAGATCGAGCAAATGAACGTTAAAATACCGAAAGACGTAATTGATTTT
TTAGCATCTAAAATCGTGTCAAACGTTAGAGAACTTGAAGGAGCTTTAAATAAAGTGATAGCTCATTCTAATTTTACTTT
AAAAGAGATTACGCTCGAAAATACACAAAATATTTTAAGAGATTTATTACGTTCTAATGAAAGAATAATTACCGTTGAAG
ATATTCAGAAAAAGGTAGCTAGCCGTTATAATATTAAATTATCCGATATGTCTTCGTCACGGAGATTACGAGAAGTGGCA
AGACCGCGTCAAATAGCTATGTATCTTAGTAAAGCATTAACGCTGAAAAGTCTTGCAGATATCGGTAAAAAATTCGGTAA
AAAAGACCACACTACGGTTATGTATGCTATTAAAAAAGTAGAAGAATTACTGGAAAACGATATAGAATTACGCGAAGAGA
TTAATTTGCTGATGAAAATATTGCAGCATTGA

Upstream 100 bases:

>100_bases
TAATATTGGTTATAAAAATTGTTATAATATTAGTGACGGCTTTGAAGGGAATAATCAAGACAAAGGCTGGAAACAAAATA
ACTTACCGTGGCAGTTTTAA

Downstream 100 bases:

>100_bases
ATATCATGTCGCGCCACCTCTGTCATCCTAGCTAACTTGATTGCGGGATGCAATAAAGAAATACTAAAATTATTAGTATT
TTAAGCTGTTCTGCTGGAGA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNTNQIILTDQGDNYVNLWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHY
NNTIKSIDIITKELPGTTQTVIELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSE
SNPLFLYGGVGLGKTHLMHAIGWYIKQNNPSRKVIYMSAEKFMYQFVKALRNKEVILFKEKFRSVDVLMIDDIQFICGKD
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDF
LASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVA
RPRQIAMYLSKALTLKSLADIGKKFGKKDHTTVMYAIKKVEELLENDIELREEINLLMKILQH

Sequences:

>Translated_463_residues
MNTNQIILTDQGDNYVNLWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHY
NNTIKSIDIITKELPGTTQTVIELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSE
SNPLFLYGGVGLGKTHLMHAIGWYIKQNNPSRKVIYMSAEKFMYQFVKALRNKEVILFKEKFRSVDVLMIDDIQFICGKD
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDF
LASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVA
RPRQIAMYLSKALTLKSLADIGKKFGKKDHTTVMYAIKKVEELLENDIELREEINLLMKILQH
>Mature_463_residues
MNTNQIILTDQGDNYVNLWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHY
NNTIKSIDIITKELPGTTQTVIELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSE
SNPLFLYGGVGLGKTHLMHAIGWYIKQNNPSRKVIYMSAEKFMYQFVKALRNKEVILFKEKFRSVDVLMIDDIQFICGKD
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDF
LASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVA
RPRQIAMYLSKALTLKSLADIGKKFGKKDHTTVMYAIKKVEELLENDIELREEINLLMKILQH

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=466, Percent_Identity=41.6309012875536, Blast_Score=374, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 53051; Mature: 53051

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNQIILTDQGDNYVNLWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNF
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
VRDWIKSKYSMVILQLFQHYNNTIKSIDIITKELPGTTQTVIELPTKTFADIGSSELNSE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHCCCCCCCCC
NIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSESNPLFLYGGVGLGKTHLMHA
CCCEEEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHH
IGWYIKQNNPSRKVIYMSAEKFMYQFVKALRNKEVILFKEKFRSVDVLMIDDIQFICGKD
HHHHEECCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHCCCCEEEECCCHHCCCCC
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
ILESKIEQMNVKIPKDVIDFLASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
DLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVARPRQIAMYLSKALTLKSLAD
HHHHCCCCEEEHHHHHHHHHHHCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
IGKKFGKKDHTTVMYAIKKVEELLENDIELREEINLLMKILQH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTNQIILTDQGDNYVNLWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNF
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
VRDWIKSKYSMVILQLFQHYNNTIKSIDIITKELPGTTQTVIELPTKTFADIGSSELNSE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHCCCCCCCCC
NIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSESNPLFLYGGVGLGKTHLMHA
CCCEEEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHH
IGWYIKQNNPSRKVIYMSAEKFMYQFVKALRNKEVILFKEKFRSVDVLMIDDIQFICGKD
HHHHEECCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHCCCCEEEECCCHHCCCCC
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
ILESKIEQMNVKIPKDVIDFLASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
DLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVARPRQIAMYLSKALTLKSLAD
HHHHCCCCEEEHHHHHHHHHHHCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
IGKKFGKKDHTTVMYAIKKVEELLENDIELREEINLLMKILQH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA