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The map label for this gene is recG [H]

Identifier: 157825974

GI number: 157825974

Start: 829627

End: 831858

Strand: Reverse

Name: recG [H]

Synonym: A1C_04600

Alternate gene names: 157825974

Gene position: 831858-829627 (Counterclockwise)

Preceding gene: 157825976

Following gene: 157825965

Centisome position: 67.57

GC content: 36.02

Gene sequence:

>2232_bases
ATGCTAACTATTCTAGAAAAATTTTTATTTTCTTCCATAAAAACGTTCATCAATATACGTGAAGATACCGTATATGCTTT
GAAGAGGCTCGGTATTAATAATATTCGTGATTTATTATTTTATCTACCTGTGTCATACAAAAATAAAATATTATGGCCCA
ATTTAACGGAAGTCAGAGACGGGGAAATAATACAAACGGAAATTGTAATTGAGAGTGTTAATTTACCGAAAAAAAGTAAT
CAGCCTTTAAAAATTACGGCTAGCCATGATACCGGTTCTTTGTTATTAGTGTTTTTTCATAAACCACCACCGTTTATTTT
TAATAAGCTGAAAGTCGGAACAAAGCATATTATTAGCGGTAAAGTACAATTTTTTGATCATTATTTGCAGATTTCGCATC
CTGAATTTATTACGAATCCTAAACTTGCAAAAGAAATAGAGCCGATTTATTCCCTGACATACTTGCTTAGTAACAAGCAG
CTATATTCATATATTATAAAAGCAATAGAGATATTTGAAGAGAAGTGTAAAGTGGTGGAAGATAAAGAAGTGAAAGAATA
TTTGGATGAGATATTGCAGAGTTTGAATGTTTTGCATGTAAGAGAGGTTGTCATACAGTTGCTTGACCACGGTATCAATA
AAAGCATAAAAAAAGACTGGATCCCGCGCTCAAGTCGCGGGATGACACAGGACAAATCTAGTAGGTATGACACTGAGTCG
TTCAAAAAACAACTAGCAGCCAAAGAACTAATCGCCAATCAAATATCTCTTTTTAATGTACGTACACAAATGAGTAGAAG
ACAAGGTAATATTTACATGAAAGCTGCAGCTATTCAAGCAAATATATTAAATGAGTTAGGATTTGAGTTAACGCAGTATC
AAAAGCAAGTCATAGAAGAAATAGAGTTTGAGCAAAGCGATAAAGTAGAAATGATGAAATTACTGCAAGGTGATGTTGGC
TCCGGTAAAACTCTGGTAGCTTTGCTTACGATTGTAAATGTGGTAAAAGCTGGATTTCAAGCAACGCTTATGGCTCCAAC
CGATTTGCTTGCCAATCAGCATTATGAGTTTTGTGTTAAAGCTTTAAAAAATACTAATATAAGAATTGCGTTACTTACCG
GTAAAATCCTTGGGGCAGCTCGAAAAAATATCATGCAGCAGCTCAAAAACGGCGAGATTGATATATTAGTCGGTACTCAT
GCTTTATTTCAAGAGAAAGTAAGCTTTAAGAAGCTAGGTTATATAGTGATCGATGAGCAGCATAGATTTGGGGTACAGCA
GCGTTTGAACCTGATAAATAAAGGACTAAATCCCGATGTTTTAGTTATGACCGCAACGCCGATTCCTCGTAGTCTTGCAC
TTACTATGTTTGGTGATATGAGTATCTCAAAGCTAATGGGTAAGCCAAAAAATCGTTTGCCTATCGCTACAAATACCATG
TCAGTTAATAAGATAGAACATATTATCGAATCGATAAATAAGAAGCTTATAGCAGGTGAGCGGGTATATTGGATTTGTCC
ATTGGTAGAGCAGAGTCCCTCCCATGATGTCATACCGAGGCTTGACCCCGGTATACAGAAAAAAATTAAAAAAGACTGGA
TCCTGTGTAGGAGCCACGGGATGACAATGGAGGAGGAGCAAGAGGATAGTTTATTAATGGATGTGATTAATCGTTTTAAC
TCTATCGAAAATATATATCAAGGTTATACCGGTATTATTCACGGTAAGATGAAGAACGAGCAGAAAGAGCAAATAATGAA
GCAGTTTAAGGCAGGTGAAATTAAGATATTAGTTGCAACAACTGTTATTGAAGTCGGAATAGACGTGCCTGAAGCGACTT
TGATCATTATTGAAAACGCTGAGAGATTTGGTCTCGCTCAGTTGCATCAGCTTAGAGGTAGAGTAGGGCGAGGCTCGTTG
CAGTCATATTGTATATTGCTCTATAATCCTAAAAGGCTTGGAAAAGTTGCACGAGGTAGGTTTGAGATAATGAAACAAAC
TAATGATGGGTTTTATATTGCTGAGCAGGATTTAAAACTGCGAGGTAGCGGTGAGGTTTTAGGAGTAAAGCAAAGCGGTG
AAATGGAGTTTTTCTTTGCTGATTTGGCAGAAGATTATGATCTATTACTTAAAGCTCATAAATTTGCGGCAATATGTTCA
AAAGGTAATTTAAATTTTATTAACTTTCAGATAAGGCTTTTCGCCAAATCGCAAGTAAGTGAATTGGTTTAG

Upstream 100 bases:

>100_bases
TTATAAAATAGCAAACAAATATAATCATGTAAACTAAAAATTCTTATTAATTTTCTTAGCAAAATCATTTAGAATATATG
TTTTAGATTCTTTAAAATAT

Downstream 100 bases:

>100_bases
GTTTAATGATTTTCGTCATTGCCGCAGCCACTTTATAGCTTTGCCATGACGATGTAGCAACGTTCGTACACTAGTGGCTG
TACCAAATACTGATACTCAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 743

Protein sequence:

>743_residues
MLTILEKFLFSSIKTFINIREDTVYALKRLGINNIRDLLFYLPVSYKNKILWPNLTEVRDGEIIQTEIVIESVNLPKKSN
QPLKITASHDTGSLLLVFFHKPPPFIFNKLKVGTKHIISGKVQFFDHYLQISHPEFITNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKVVEDKEVKEYLDEILQSLNVLHVREVVIQLLDHGINKSIKKDWIPRSSRGMTQDKSSRYDTES
FKKQLAAKELIANQISLFNVRTQMSRRQGNIYMKAAAIQANILNELGFELTQYQKQVIEEIEFEQSDKVEMMKLLQGDVG
SGKTLVALLTIVNVVKAGFQATLMAPTDLLANQHYEFCVKALKNTNIRIALLTGKILGAARKNIMQQLKNGEIDILVGTH
ALFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGLNPDVLVMTATPIPRSLALTMFGDMSISKLMGKPKNRLPIATNTM
SVNKIEHIIESINKKLIAGERVYWICPLVEQSPSHDVIPRLDPGIQKKIKKDWILCRSHGMTMEEEQEDSLLMDVINRFN
SIENIYQGYTGIIHGKMKNEQKEQIMKQFKAGEIKILVATTVIEVGIDVPEATLIIIENAERFGLAQLHQLRGRVGRGSL
QSYCILLYNPKRLGKVARGRFEIMKQTNDGFYIAEQDLKLRGSGEVLGVKQSGEMEFFFADLAEDYDLLLKAHKFAAICS
KGNLNFINFQIRLFAKSQVSELV

Sequences:

>Translated_743_residues
MLTILEKFLFSSIKTFINIREDTVYALKRLGINNIRDLLFYLPVSYKNKILWPNLTEVRDGEIIQTEIVIESVNLPKKSN
QPLKITASHDTGSLLLVFFHKPPPFIFNKLKVGTKHIISGKVQFFDHYLQISHPEFITNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKVVEDKEVKEYLDEILQSLNVLHVREVVIQLLDHGINKSIKKDWIPRSSRGMTQDKSSRYDTES
FKKQLAAKELIANQISLFNVRTQMSRRQGNIYMKAAAIQANILNELGFELTQYQKQVIEEIEFEQSDKVEMMKLLQGDVG
SGKTLVALLTIVNVVKAGFQATLMAPTDLLANQHYEFCVKALKNTNIRIALLTGKILGAARKNIMQQLKNGEIDILVGTH
ALFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGLNPDVLVMTATPIPRSLALTMFGDMSISKLMGKPKNRLPIATNTM
SVNKIEHIIESINKKLIAGERVYWICPLVEQSPSHDVIPRLDPGIQKKIKKDWILCRSHGMTMEEEQEDSLLMDVINRFN
SIENIYQGYTGIIHGKMKNEQKEQIMKQFKAGEIKILVATTVIEVGIDVPEATLIIIENAERFGLAQLHQLRGRVGRGSL
QSYCILLYNPKRLGKVARGRFEIMKQTNDGFYIAEQDLKLRGSGEVLGVKQSGEMEFFFADLAEDYDLLLKAHKFAAICS
KGNLNFINFQIRLFAKSQVSELV
>Mature_743_residues
MLTILEKFLFSSIKTFINIREDTVYALKRLGINNIRDLLFYLPVSYKNKILWPNLTEVRDGEIIQTEIVIESVNLPKKSN
QPLKITASHDTGSLLLVFFHKPPPFIFNKLKVGTKHIISGKVQFFDHYLQISHPEFITNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKVVEDKEVKEYLDEILQSLNVLHVREVVIQLLDHGINKSIKKDWIPRSSRGMTQDKSSRYDTES
FKKQLAAKELIANQISLFNVRTQMSRRQGNIYMKAAAIQANILNELGFELTQYQKQVIEEIEFEQSDKVEMMKLLQGDVG
SGKTLVALLTIVNVVKAGFQATLMAPTDLLANQHYEFCVKALKNTNIRIALLTGKILGAARKNIMQQLKNGEIDILVGTH
ALFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGLNPDVLVMTATPIPRSLALTMFGDMSISKLMGKPKNRLPIATNTM
SVNKIEHIIESINKKLIAGERVYWICPLVEQSPSHDVIPRLDPGIQKKIKKDWILCRSHGMTMEEEQEDSLLMDVINRFN
SIENIYQGYTGIIHGKMKNEQKEQIMKQFKAGEIKILVATTVIEVGIDVPEATLIIIENAERFGLAQLHQLRGRVGRGSL
QSYCILLYNPKRLGKVARGRFEIMKQTNDGFYIAEQDLKLRGSGEVLGVKQSGEMEFFFADLAEDYDLLLKAHKFAAICS
KGNLNFINFQIRLFAKSQVSELV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=703, Percent_Identity=33.0014224751067, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1787357, Length=464, Percent_Identity=33.1896551724138, Blast_Score=243, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 84734; Mature: 84734

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTILEKFLFSSIKTFINIREDTVYALKRLGINNIRDLLFYLPVSYKNKILWPNLTEVRD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECCCCCCCCC
GEIIQTEIVIESVNLPKKSNQPLKITASHDTGSLLLVFFHKPPPFIFNKLKVGTKHIISG
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCHHHHCC
KVQFFDHYLQISHPEFITNPKLAKEIEPIYSLTYLLSNKQLYSYIIKAIEIFEEKCKVVE
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
DKEVKEYLDEILQSLNVLHVREVVIQLLDHGINKSIKKDWIPRSSRGMTQDKSSRYDTES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHH
FKKQLAAKELIANQISLFNVRTQMSRRQGNIYMKAAAIQANILNELGFELTQYQKQVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHH
IEFEQSDKVEMMKLLQGDVGSGKTLVALLTIVNVVKAGFQATLMAPTDLLANQHYEFCVK
HCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHH
ALKNTNIRIALLTGKILGAARKNIMQQLKNGEIDILVGTHALFQEKVSFKKLGYIVIDEQ
HHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCEEEEECH
HRFGVQQRLNLINKGLNPDVLVMTATPIPRSLALTMFGDMSISKLMGKPKNRLPIATNTM
HHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHEEHHHCCCHHHHHHCCCCCCCCEEECCC
SVNKIEHIIESINKKLIAGERVYWICPLVEQSPSHDVIPRLDPGIQKKIKKDWILCRSHG
CHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
MTMEEEQEDSLLMDVINRFNSIENIYQGYTGIIHGKMKNEQKEQIMKQFKAGEIKILVAT
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
TVIEVGIDVPEATLIIIENAERFGLAQLHQLRGRVGRGSLQSYCILLYNPKRLGKVARGR
EEHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHH
FEIMKQTNDGFYIAEQDLKLRGSGEVLGVKQSGEMEFFFADLAEDYDLLLKAHKFAAICS
HHHHHCCCCCEEEEECCEEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
KGNLNFINFQIRLFAKSQVSELV
CCCCEEEEEEEEEEEHHHHHHCC
>Mature Secondary Structure
MLTILEKFLFSSIKTFINIREDTVYALKRLGINNIRDLLFYLPVSYKNKILWPNLTEVRD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECCCCCCCCC
GEIIQTEIVIESVNLPKKSNQPLKITASHDTGSLLLVFFHKPPPFIFNKLKVGTKHIISG
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCHHHHCC
KVQFFDHYLQISHPEFITNPKLAKEIEPIYSLTYLLSNKQLYSYIIKAIEIFEEKCKVVE
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
DKEVKEYLDEILQSLNVLHVREVVIQLLDHGINKSIKKDWIPRSSRGMTQDKSSRYDTES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHH
FKKQLAAKELIANQISLFNVRTQMSRRQGNIYMKAAAIQANILNELGFELTQYQKQVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHH
IEFEQSDKVEMMKLLQGDVGSGKTLVALLTIVNVVKAGFQATLMAPTDLLANQHYEFCVK
HCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHH
ALKNTNIRIALLTGKILGAARKNIMQQLKNGEIDILVGTHALFQEKVSFKKLGYIVIDEQ
HHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCEEEEECH
HRFGVQQRLNLINKGLNPDVLVMTATPIPRSLALTMFGDMSISKLMGKPKNRLPIATNTM
HHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHEEHHHCCCHHHHHHCCCCCCCCEEECCC
SVNKIEHIIESINKKLIAGERVYWICPLVEQSPSHDVIPRLDPGIQKKIKKDWILCRSHG
CHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
MTMEEEQEDSLLMDVINRFNSIENIYQGYTGIIHGKMKNEQKEQIMKQFKAGEIKILVAT
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
TVIEVGIDVPEATLIIIENAERFGLAQLHQLRGRVGRGSLQSYCILLYNPKRLGKVARGR
EEHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHH
FEIMKQTNDGFYIAEQDLKLRGSGEVLGVKQSGEMEFFFADLAEDYDLLLKAHKFAAICS
HHHHHCCCCCEEEEECCEEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
KGNLNFINFQIRLFAKSQVSELV
CCCCEEEEEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]