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The map label for this gene is purC [H]

Identifier: 157825425

GI number: 157825425

Start: 303728

End: 304438

Strand: Direct

Name: purC [H]

Synonym: A1C_01630

Alternate gene names: 157825425

Gene position: 303728-304438 (Clockwise)

Preceding gene: 157825424

Following gene: 157825426

Centisome position: 24.67

GC content: 31.93

Gene sequence:

>711_bases
ATGAAAACACAAATTTACAAAGGTTCAAGTAAAATTTTATATTCTGCCGAAGAAGATTTTTTACTTATAATGGCATTTTC
TGATAATGGTATCTTAGAAAGTGGTGAAATTATTGAGGTCTCAGGCAAGGGGGTACTTAATAATAATATTTCTTCCTTTC
TAATGGATAAACTGGAAATGATTGGCATTGAAAATCATTTTATCGAAAAAATAAATATGAGGGAGCAATTAATTCAATAT
GTTGAGGTTTTTCCGGTACAAGTAATAATATCATCAGTAGCGTGTGGTAGATTTGTAAAAGAATTTGGAATGGACGAAGG
GTATGTGTTTGATAAACCTATAATCGATTTTAAGGTCCGAAGCCGTGAATTTAAATATCCGATAGTTAATGAGTATCAAA
TATTGAATTTCAGCTGGTTAACTCTTGATGAAATTAAAGCAGTAAAAGAGCAGGCTTTGCGTATATATGCTTTTCTAAGT
GGCTTATTTATGGGCGTCGGGATTCGGCTTGTTGAGTGTAAATTAGAATTTGGGCGTGTGTTGAATGGTGAAGAATCTAT
CATTATGTTAACTGATGAAATTAGTCCGGATAATTGTAGATTATGGCATATTCACAGTAATGAAAAATTAGGGTTTGAAT
TGCTTGAAAACAAGCCGAATAAAGCTTTTGAATCATATCAGCTAATAGCGGATCGTTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
ATGGTTTGAGAGAGGTTTAATGTCATTCCTGCAAAAGCAGGAATGACATATGTATCCACGCAGGCGATGACGAGGACAAT
GAATTTTGAGAAAATAACAA

Downstream 100 bases:

>100_bases
ATATATTTTTTAAGCGGTATATGATATTTCGGATTTGAAAAACACTTCGATGTCATACCGGTTTTGTTGTATGGTTCGTT
TTCATCGTTATTGCGAGCAG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKTQIYKGSSKILYSAEEDFLLIMAFSDNGILESGEIIEVSGKGVLNNNISSFLMDKLEMIGIENHFIEKINMREQLIQY
VEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVRSREFKYPIVNEYQILNFSWLTLDEIKAVKEQALRIYAFLS
GLFMGVGIRLVECKLEFGRVLNGEESIIMLTDEISPDNCRLWHIHSNEKLGFELLENKPNKAFESYQLIADRLKEK

Sequences:

>Translated_236_residues
MKTQIYKGSSKILYSAEEDFLLIMAFSDNGILESGEIIEVSGKGVLNNNISSFLMDKLEMIGIENHFIEKINMREQLIQY
VEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVRSREFKYPIVNEYQILNFSWLTLDEIKAVKEQALRIYAFLS
GLFMGVGIRLVECKLEFGRVLNGEESIIMLTDEISPDNCRLWHIHSNEKLGFELLENKPNKAFESYQLIADRLKEK
>Mature_236_residues
MKTQIYKGSSKILYSAEEDFLLIMAFSDNGILESGEIIEVSGKGVLNNNISSFLMDKLEMIGIENHFIEKINMREQLIQY
VEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVRSREFKYPIVNEYQILNFSWLTLDEIKAVKEQALRIYAFLS
GLFMGVGIRLVECKLEFGRVLNGEESIIMLTDEISPDNCRLWHIHSNEKLGFELLENKPNKAFESYQLIADRLKEK

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788820, Length=233, Percent_Identity=30.4721030042918, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 27261; Mature: 27261

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQIYKGSSKILYSAEEDFLLIMAFSDNGILESGEIIEVSGKGVLNNNISSFLMDKLEM
CCCEEEECCCEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCEECCCHHHHHHHHHHH
IGIENHFIEKINMREQLIQYVEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEC
SREFKYPIVNEYQILNFSWLTLDEIKAVKEQALRIYAFLSGLFMGVGIRLVECKLEFGRV
CCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHC
LNGEESIIMLTDEISPDNCRLWHIHSNEKLGFELLENKPNKAFESYQLIADRLKEK
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTQIYKGSSKILYSAEEDFLLIMAFSDNGILESGEIIEVSGKGVLNNNISSFLMDKLEM
CCCEEEECCCEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCEECCCHHHHHHHHHHH
IGIENHFIEKINMREQLIQYVEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEC
SREFKYPIVNEYQILNFSWLTLDEIKAVKEQALRIYAFLSGLFMGVGIRLVECKLEFGRV
CCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHC
LNGEESIIMLTDEISPDNCRLWHIHSNEKLGFELLENKPNKAFESYQLIADRLKEK
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA