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The map label for this gene is aspS [H]

Identifier: 157825326

GI number: 157825326

Start: 199154

End: 200962

Strand: Direct

Name: aspS [H]

Synonym: A1C_01040

Alternate gene names: 157825326

Gene position: 199154-200962 (Clockwise)

Preceding gene: 157825325

Following gene: 157825340

Centisome position: 16.18

GC content: 37.92

Gene sequence:

>1809_bases
ATGCATAAATACAGGACTCATAATTGTAGCGAATTACAAATATCCGATGTTGGGCAAGAAGTTAAATTATCCGGCTGGGT
ACATAGAAGAAGAGATCACGGTAATCTGGTTTTCATAGATCTGCGTGATCATTACGGTATAATTCAAATCGTATTTACCG
ATCAAAATCCACAGCTTATGGAGGATGCTAGCCGTTTGCGTTATGAGTCGGTAGTTACGGTACGTGGTACAGTTGTAGCA
AGGTCAGAGGACACAATTAATAATACGCTGCCGACAGGTCATGTTGAAGTGCTAGCTGTAGAATTTATTGTTGAGTCAGC
TGCAGACACTTTACCTTTTGTTATTAATACCGAAAAAGACGCTCCGGAAGATTCAAGGCTTAAACATCGTTTTTTAGATC
TTAGACGTGAGAAATTGCATAATAATATAATACTCCGCTCACAAATTATTTCGCATATTCGTCACTTGATGATGGCAAGA
GGTTTTACCGAATTTCAAACGCCAATCCTAACTGCTAGCTCTCCTGAAGGTGCTAGGGATTTCTTAGTACCGAGTAGAAT
GCATCCTGGTAAGTTCTATGCATTACCGCAAGCACCTCAGCAATTCAAGCAACTCTTGATGGTTTCAGGCTTTGATCGTT
ATTTCCAAATTGCTCCTTGCTTTCGGGATGAAGATGCAAGAGCAGATAGATCACCAGGCGAGTTTTATCAGCTAGATTTA
GAAATGTCGTTTGTTACACAGGAAGATGTATTTAGTACTATTGAGCCTGTGATGTATGATTTATTTAATAAATTTACGGA
TAAGAAAGTATCAGCGACTCCTTTCGTTCGTATTCCATATAATGAATCTATGCTAAAATACGGCTCTGATAAACCTGACT
TACGTAACACTATTATAATTTCCGATGTAACTGAGATATTTAGAGATTCCGATTTTACTATTTTCAGGGAAAATATTAGA
AAAGGAAGCATAGTGCGTGCAATTCCTGCACCTAAGGCAGCTACAATGCCTCGTAGTTTCTTCGATAAAATGATAGAGTT
TGCGATATCAGAAGGAGCAGGTGGACTTGGCTACATTCAGTTTAGTGAAACCGGTGAAACAAAAGGAGCGGTAGCAAAAT
TCTTAAGCACGCAGCAATTAGATAGTCTAAAAGCTACAGCTAGTATTAGTAACGGTGATGCCGTATTTTTTGTTAGCGAT
AAAAAAGAAAAAGCTGCAAGGCTTGCAGGTAAGGTTAGAATAAGACTTGGTGAAGAGCTTGATTTACTTGAAAAAGATTG
CTTTAAATTCTGTTGGATTACTGATTTTCCATTTTATGAATTAAATGAAGAAACAGGTAAGATTGATTTTAGCCATAATC
CATTTTCTATGCCACAAGGTGGTTTGGAAGCCTTAGAAAATGCTAAAACAACTGAAGCACTACTTGAACTTAATGCATAC
CAATATGATATTGTTTGTAACGGTATTGAGCTTTCCAGCGGTGCTATTAGAAACCATAAGCCAGACATTATGTATAAAGC
ATTTTCCATAGCAGGTTATAGTGAGGAAGAAGTTAATAAAAGATTTGGTGGTATGATTAGAGCGTTTAAGTTCGGTGCTC
CACCGCATGGCGGAATAGCTCCCGGTATTGACAGAATCGTTATGCTACTCGCAGAAGCGACTAATATAAGAGAAGTAATT
GCATTTCCTTTAAATCAGCAAGCTGAAGATTTACTAATGAACGCTCCAAGCTATGTAGAAGATAAAGCTCTGAAAGAGCT
CAGCATTATGCTATCACCGTCAGCTAGAAAAAACGCAAAGAAAGAATAA

Upstream 100 bases:

>100_bases
AGCTGCTGCAATATCAAGATAAAACTTTAGTTGCTATTTGTAAAAATTTGCGATTTTATGTATATATAATATAGGGGAAA
TCTATAATAAAGAAATAGAA

Downstream 100 bases:

>100_bases
GCATTTATAATTGTTGCTTAGGGGTTATATGACACTGTTGTATGACTAGCTCAGTCGTCATTGTGAGCAAGCATTGTTTT
GCGTGGACCGGCAAAAAACC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLMEDASRLRYESVVTVRGTVVA
RSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKDAPEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMAR
GFTEFQTPILTASSPEGARDFLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDL
EMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIIISDVTEIFRDSDFTIFRENIR
KGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQFSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSD
KKEKAARLAGKVRIRLGEELDLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAY
QYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIAPGIDRIVMLLAEATNIREVI
AFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAKKE

Sequences:

>Translated_602_residues
MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLMEDASRLRYESVVTVRGTVVA
RSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKDAPEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMAR
GFTEFQTPILTASSPEGARDFLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDL
EMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIIISDVTEIFRDSDFTIFRENIR
KGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQFSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSD
KKEKAARLAGKVRIRLGEELDLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAY
QYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIAPGIDRIVMLLAEATNIREVI
AFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAKKE
>Mature_602_residues
MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLMEDASRLRYESVVTVRGTVVA
RSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKDAPEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMAR
GFTEFQTPILTASSPEGARDFLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDL
EMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIIISDVTEIFRDSDFTIFRENIR
KGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQFSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSD
KKEKAARLAGKVRIRLGEELDLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAY
QYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIAPGIDRIVMLLAEATNIREVI
AFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAKKE

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=612, Percent_Identity=35.6209150326797, Blast_Score=353, Evalue=3e-97,
Organism=Homo sapiens, GI45439306, Length=345, Percent_Identity=24.9275362318841, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4758762, Length=283, Percent_Identity=26.8551236749117, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI226491502, Length=268, Percent_Identity=25.3731343283582, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI5031815, Length=264, Percent_Identity=25.3787878787879, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI194272210, Length=264, Percent_Identity=25.3787878787879, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788173, Length=600, Percent_Identity=41.6666666666667, Blast_Score=464, Evalue=1e-131,
Organism=Escherichia coli, GI1790571, Length=302, Percent_Identity=27.1523178807947, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789256, Length=295, Percent_Identity=27.4576271186441, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32566633, Length=611, Percent_Identity=32.8968903436989, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17551876, Length=276, Percent_Identity=30.0724637681159, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71984122, Length=299, Percent_Identity=27.7591973244147, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325153, Length=318, Percent_Identity=37.1069182389937, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323011, Length=306, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321807, Length=287, Percent_Identity=26.4808362369338, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584738, Length=598, Percent_Identity=37.2909698996655, Blast_Score=345, Evalue=4e-95,
Organism=Drosophila melanogaster, GI17136276, Length=285, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921528, Length=228, Percent_Identity=31.140350877193, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 68112; Mature: 68112

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLM
CCCCCCCCCCEEEHHHCCCCEEHHHHHHEECCCCCEEEEEECCCCCEEEEEEECCCCHHH
EDASRLRYESVVTVRGTVVARSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKD
HHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
APEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMARGFTEFQTPILTASSPEGARD
CCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCCCHH
FLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDL
CCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEE
EMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIII
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCEEEE
SDVTEIFRDSDFTIFRENIRKGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQ
HHHHHHHCCCCCEEEHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
FSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSDKKEKAARLAGKVRIRLGEEL
ECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHCEEEEEECCCH
DLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAY
HHHHHHHHHEEEECCCCCEECCCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCE
QYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIA
EEEEEECCEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PGIDRIVMLLAEATNIREVIAFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAK
CCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCC
KE
CC
>Mature Secondary Structure
MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLM
CCCCCCCCCCEEEHHHCCCCEEHHHHHHEECCCCCEEEEEECCCCCEEEEEEECCCCHHH
EDASRLRYESVVTVRGTVVARSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKD
HHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
APEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMARGFTEFQTPILTASSPEGARD
CCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCCCHH
FLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDL
CCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEE
EMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIII
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCEEEE
SDVTEIFRDSDFTIFRENIRKGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQ
HHHHHHHCCCCCEEEHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
FSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSDKKEKAARLAGKVRIRLGEEL
ECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHCEEEEEECCCH
DLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAY
HHHHHHHHHEEEECCCCCEECCCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCE
QYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIA
EEEEEECCEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PGIDRIVMLLAEATNIREVIAFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAK
CCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA