| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is rpoB [H]
Identifier: 157825320
GI number: 157825320
Start: 185804
End: 189925
Strand: Direct
Name: rpoB [H]
Synonym: A1C_01010
Alternate gene names: 157825320
Gene position: 185804-189925 (Clockwise)
Preceding gene: 157825319
Following gene: 157825321
Centisome position: 15.09
GC content: 34.59
Gene sequence:
>4122_bases ATGGTTTCATTAAGGGATAATATAGAAGCACAACCCTTGTCACATAATAGAAGAATAAGAAAAAATTTCGGTCACATAAA TTTAGTAGCAGATATACCAAATTTGATTGAAATTCAAAAAAATTCATATGAAAAAAACTTTCTACAGTTAAATATTAAAG ATTCTGAAAGAAAAAATAAAGGTTTACAATCTATATTAAACTCAATTTTTCCTATTTCAGATTCCTCCAATATTGCTAAT TTAGAATTTGTAAAATATGAATTCGATACTCCAAAATATGATGTAGAAGAATGTAGTCAAAGAAGTTTAAGTTATGCTGC TCCTCTTAAAGTTACTTTAAGGTTAAGTATTTGGGATATAGATGAGGATACCGGTACTAGAGAAATTAAAGGGATTAAAG AGCAAGAAGTATATATGGGTGATATCCCATTAATGACTAAAAACGGTACTTTTATCATTAATGGTACAGAAAGGGTAGTT GTGTCGCAAATGCATCGCTCACCTGGTGTATTCTTTTATCATGATGAAGGAAAAGTCCACTCTTCCGGCAAGCTTTTATA TTCTGCTCGTGTTATTCCATATAGAGGATCTTGGCTTGATTTAGAATTCGATGCTAAAGATGTTCTTTATTTCAGGATTG ATAGAAAAAGAAAGCTTTATGCTACTACTTTGCTTAGAGCTATAGGTATGAGTACTGAAGAAATTATAAAATTTTATTAT AATTCAGTAACTTATAAGCTTGTTAAAAAGAAAGGTTGGGCGGTTAAATTTATACCTAAGCATATTACTGCTCATCGTTT AACCAGTGATTTAGTAGATGCAGATACTGGAAATGTTCTACTGAAGGCAGGACAAAAAATTACCCCGCGTTTGGCTCAAA AATATTGTGCTGAAGGTATTAATAATATTTTAGTAGCTCATGAAACTTTAATCGGCAAATATCTATCCGAAGATTTAAGA GATCCTGCAAGCGATGAAGTATTAGCAAAAATCGGTGAAATAATAACTAGCGATATGCTAAATGTTATTAATGATCTTAA AATTAAAAATGTTAACGTATTAGTAATCAACCCTCAGTCCGGTCCATATATAAGAAATACCTTATTTGCTGATAAGAATC AGGACCGTGAGGCAGCATTATGTGACATTTTTAGAGTTTTAAGACCAGGTGAACCTACTAATATAGAAGCGGCTGAAAGC CTGTTTTATAATTTATTCTTTGATTCTGAAAGATATGATCTTTCAGAAGTCGGACGAATAAAAATGAATTCTAGGTTAGG GCTTAGTATTTCTGAAGAAGTTACGGTTTTAACAATTGATGATATTAAAAATATCGTAAGAGTTTTGGTAGAGCTTAAAG ATGGTAAAGGTATAATAGACGATATTGATCATTTAGGTAATAGAAGGGTTAGATCGGTAGGTGAATTGATAGAAAATCAA TTTAGAATAGGTTTAGTCCGAATGGAAAAATCTGTAATTGAAAGGATGTCGGCAGGTGATGTTGATACCGTAATGCCTCA TGATTTAGTAAATTCCAAGATTTTAGTTTCAGTCGTAAAAGAATTTTTTAGTACCTCCCAATTATCACAATTTATGGATC AAACAAATCCATTATCGGAAATAACACATAAAAGAAGGCTGTCGGCACTCGGTCCTGGAGGTCTTAGTCGAGATCGAGCA GGTTTTGAGGTGCGTGATGTACATCCTACTCATTACGGGCGTATTTGTCCTATTGAAACACCTGAAGGTCAGAATATCGG GTTAATTAACTCTATGGCTACTTACGCTAGGATAAATAAACACGGTTTTATAGAGAGTCCGTATAGAAAAGTTAAAGATG GGCGTGTAATCGATGAAGTGATATATCTTTCTGCTATTGAAGAAGGTAAATACAAAATCGGACAGGCAAATTCTAAAGTT GATCGAGATGGAAAGCTGCAAGGAGAGTTTATTAATTGTCGTGTTGAAGGCGGTAATTTTGTAATGGTAGAACCGCATGA GGTAGATTTTATTGATGTGACTCCTATGCAGGTAGTATCGGTTGCGGCTTCTCTTATACCGTTCTTAGAAAACGATGATG CTAACCGTGCTTTGATGGGGTCAAACATGCAAAGACAAGCTGTTCCTTTAATTAAAACGGATGCACCTTTTGTAGGTACC GGAGTTGAAGGGGTAGTAGCTAAAGATTCTGGAGCGTCTGTGCTTGCATTACATGACGGTATTGTTGAGCAGGTAGATTC AAATAGAATCGTGATTAGAACTCTAGAACAAAAAATTGATGGTTCTCCTTCTGTTTATATTTATAATTTATTAAAATTCC AAAAGTCCAATCATAATACTTGTATAAATCAAAAGCCTTTAGTTCAGGTTGGTCATTATGTTAAGAAAAACGATATTATA GCTGACGGTCCTAGTACGGATAACGGTGAAATTGCTTTAGGTAGAAACGTGCTTGTGGCTTTCTTACCTTGGAACGGTTA CAATTTTGAAGATTCAATTTTAATATCTGAACGTATAGTAAAAGAGGATATATTTACATCGATTCATATTGAAGAATTTG AAGTAATAGCTAGAGATACACGCCTTGGTCCTGAAGAAATTACCCGTGATATACCGAATGTAAGTGAAGAAGCGTTGCGT CATCTTGATGAAGTCGGAATAATTTATGTAGGTGCAGAAGTAAAAGCCGGTGATATTTTAGTCGGAAAAGTAACACCGAA AAGTGAATCGCCTATTACTCCTGAAGAGAAGCTACTACGTGCTATTTTTGGGGAGAAAGCTTTTGATGTAAAAGATTCAT CGCTGCATGTACCTTCTGGAGTGAGCGGAACTGTAGTAGAAGTAAGGGTCTTTTCTCGTAGGGGTGTAGAAAAAGACCAG CGAGCTATTGCTATTGAAAAACAACAAATTGAAAAATTAGCAAAAGACAGAGATGATGAATTAGAAATTATTGAGCATTT TGTGTTTAGTTTGCTTGAAAAGCTTTTAGTAGGGCAGGTGATTATTAACGGTCTTAAGCAAGTAAAAGCAGGACAAACTA TTACTACTGAAATGCTAAAAGGTTTATCTAAAGGGCAGTTTTGGCAGCTTACTGTGGAAGATGCAAATGTAATGAATGAA ATAGAGCAGATAAAGATTCATTATGATGAGAAAAAAGATGCCCTCAATAAAAGATTTGCTACTAAGGTAGAGAAATTGCA AAGCGGTGATGATTTACCTCAGGGAGCTTTAAAAGTAGTAAAAGTATTTATCGCAACTAAGCATAAATTACAGCCTGGTG ATAAGATGGCAGGAAGGCACGGAAATAAAGGTGTTGTTTCACGTATCGTACCTGAAGAAGATATGCCATTTTTAGAAGAT GGAACTGTGGTAGATATTGTTCTAAATCCTCTAGGTCTTCCGTCACGTATGAATATAGGACAGATTTTAGAAACGCATCT TGGGTGGGCATCAATAAATTTAGCACAAAAAATATCTACATTAGTAAAGGAATATAAAAATAAAAATATAGGTATTGAGA AAATTAAGAAATTCTTACTTGAGCTATACGGAGAGAATATTAATTATATACTTGAAAGATCTGAAGAAGAGATTATCTCC TTCTGTAATAAAGTAGGTAAAGGCGTATATTTTGCAACTCCTGTATTTGACGGAGCAAAAGTTCAGGACGTTAAAGATAT GTTAAAACTTGCCGGTCAAGATCCTTCAGGACAAGTAAAATTAATTGATGGTAGAACCGGTGAATATTTTGACCGTCTAG TGACTGTTGGACAGAAATATTTGCTGAAGCTGCATCACTTAGTCGATAATAAAATTCACTCTCGTTCTATAGGACCTTAT AGCTTAGTAACGCAGCAACCGCTTGGAGGTAAGTCTCATTTCGGTGGACAGCGTTTCGGAGAAATGGAATGCTGGGCATT ACAAGCTTACGGTGCGGCCTATACGTTACAGGAAATGTTAACTGTTAAGTCAGATGACGTAAACGGTAGGATTAAAACTT ATGATTCTATAGTACGTGGTGAAAATAATTTTGAATCAGGTATTCCTGAATCATTTAATGTGATGATAAAAGAATTTAGA TCTTTATGTCTTAACGTAAAGCTTGAAGTAACTTCGAGTTAA
Upstream 100 bases:
>100_bases TTTACAGCTAAAAAGAGTCATAATTATAATTGTTCTATTAAAAATGCATAGGACCTAATCACTTCAATACGGGCAGTAAT TTTATCAGTCGGGAGATTAT
Downstream 100 bases:
>100_bases ATGTGTACTCGGTGAATTTCAAAAATTGGCTACGTCGTCTAGCAAATTTTGTGGTGCTAACGTATTAAGTATACGCTCCG CTCCTCGTCTTACGGACTCC
Product: DNA-directed RNA polymerase subunit beta
Products: NA
Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]
Number of amino acids: Translated: 1373; Mature: 1373
Protein sequence:
>1373_residues MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR SLCLNVKLEVTSS
Sequences:
>Translated_1373_residues MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR SLCLNVKLEVTSS >Mature_1373_residues MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR SLCLNVKLEVTSS
Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]
COG id: COG0085
COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the RNA polymerase beta chain family [H]
Homologues:
Organism=Homo sapiens, GI238908503, Length=303, Percent_Identity=29.3729372937294, Blast_Score=128, Evalue=4e-29, Organism=Homo sapiens, GI238908505, Length=303, Percent_Identity=29.3729372937294, Blast_Score=128, Evalue=4e-29, Organism=Homo sapiens, GI33469941, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=2e-27, Organism=Homo sapiens, GI212286172, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=3e-27, Organism=Homo sapiens, GI4505941, Length=315, Percent_Identity=29.8412698412698, Blast_Score=120, Evalue=7e-27, Organism=Escherichia coli, GI1790419, Length=1363, Percent_Identity=54.512105649303, Blast_Score=1490, Evalue=0.0, Organism=Caenorhabditis elegans, GI25144348, Length=248, Percent_Identity=31.8548387096774, Blast_Score=123, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17552304, Length=248, Percent_Identity=32.258064516129, Blast_Score=111, Evalue=3e-24, Organism=Saccharomyces cerevisiae, GI6324781, Length=305, Percent_Identity=30.1639344262295, Blast_Score=126, Evalue=3e-29, Organism=Saccharomyces cerevisiae, GI6325267, Length=249, Percent_Identity=31.3253012048193, Blast_Score=107, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6324725, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI17647877, Length=247, Percent_Identity=31.1740890688259, Blast_Score=118, Evalue=3e-26, Organism=Drosophila melanogaster, GI17136444, Length=310, Percent_Identity=27.0967741935484, Blast_Score=107, Evalue=5e-23, Organism=Drosophila melanogaster, GI17136446, Length=280, Percent_Identity=28.9285714285714, Blast_Score=104, Evalue=5e-22,
Paralogues:
None
Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR010243 - InterPro: IPR019462 - InterPro: IPR015712 - InterPro: IPR007120 - InterPro: IPR007121 - InterPro: IPR007644 - InterPro: IPR007642 - InterPro: IPR007645 - InterPro: IPR007641 - InterPro: IPR014724 [H]
Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]
EC number: =2.7.7.6 [H]
Molecular weight: Translated: 154166; Mature: 154166
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: PS01166 RNA_POL_BETA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE SSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGI HHHHEEEHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHH NNILVAHETLIGKYLSEDLRDPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQS HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC GPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAESLFYNLFFDSERYDLSEVGRI CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCEE KMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ EECCCCCCEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC HGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKVDRDGKLQGEFINCRVEGGNF CCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCE VMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT EEECCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNT CCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEEHHHHHCCCCCEEEEEEHHHHCCCCCC CINQKPLVQVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV CCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH KEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYVGAEVKAGDIL HHHHHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLK HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH GLSKGQFWQLTVEDANVMNEIEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVV CCCCCCEEEEEECCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH KVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH QILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC >Mature Secondary Structure MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE SSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGI HHHHEEEHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHH NNILVAHETLIGKYLSEDLRDPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQS HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC GPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAESLFYNLFFDSERYDLSEVGRI CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCEE KMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ EECCCCCCEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC HGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKVDRDGKLQGEFINCRVEGGNF CCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCE VMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT EEECCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNT CCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEEHHHHHCCCCCEEEEEEHHHHCCCCCC CINQKPLVQVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV CCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH KEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYVGAEVKAGDIL HHHHHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLK HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH GLSKGQFWQLTVEDANVMNEIEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVV CCCCCCEEEEEECCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH KVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH QILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9555894; 9823893; 10508014 [H]