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The map label for this gene is hflK [H]

Identifier: 157825299

GI number: 157825299

Start: 169191

End: 170228

Strand: Direct

Name: hflK [H]

Synonym: A1C_00905

Alternate gene names: 157825299

Gene position: 169191-170228 (Clockwise)

Preceding gene: 157825295

Following gene: 157825300

Centisome position: 13.74

GC content: 33.24

Gene sequence:

>1038_bases
ATGCTTAGTAAAAAATATAGCTCGATTTTAAAAAAATCCCCATGGAAAGATTGTGATTCTAATCAAGACGATAACATATT
CACAAGACCGCGTAAAAATCAATTTAATTTTGATAAATTTCAATTCCAGTTTAATTTCAATGTTAAAACAATAATTTTAG
CTGTTGTCGCAGTGATTGCTTTATGGCTTGCGTCCGGTATTTATGAAATAAAAGAAGGTGATGAAGCAGCGGTAATAAGA
TTTGGGCGTTTTGTACGTAAGGGCTACCCCGGGCTTAATTATCATTTACCTGTCCCTTTTGAAAAGATAATAGTTGAGAA
AGTTAAACAATCACGGCGAATTGAGATTGGTTATCGTACAAATAACTCGGTACGTAGCGGTGGCGATAATACTAAAAATA
TTGCCGGTGAAAGTATAATGCTTACCGGTGATGAAAATATTGTTGCTTTAAATTGTGACGTAATGTGGCATATTAATAAC
CTTGAGGATTTTATTTTTAACGTACAAAGACCTGCAGAAACAGTAAAAGCAACAGTAGAAAGTGCTGTTAGAGAAGTAAT
AGGCAATACTCCTATTTCTTGTGTATTATCTGATCAAAAGCAAGAAATTACTTACAAAATAGAAAAATTAGCACAAAAGA
TACTGGATAGTTATAATGCCGGTGTGATGATTGAGAAAGTACAATTACTAAAAGCCGAGCCGCCTGCCGAAGTAATAGAT
TCTTATAGAGACGTGCAAACTTCAAAAGCAGATAAAGAAAAAGAAATAAATCAAGCTCAAGCCTATAATAATAAGATTTT
GCCGGAAGCTAGAGGAGCAGCCGCAAAGATTATACAAGAAGCAGAAGGTTATAGAGAAGAAGTTATATCAAAAGCAGAAG
GTGATAGCCAAAGATTTAATGCTATTTATAAACAATATACTGTAGGTAGGCAAGTAACTAGAGATAGGTTATATTTAGAA
GTAGTCGAAGAGATATTAGGTGGTTCAAATAAAACTATTATTAATAATGCACTACTACCACACATGGTTATAAAATAA

Upstream 100 bases:

>100_bases
TAATTAAATTTCCTTTTTAAGGCTGTTTAAGTTCATAACTTGACGTTATATGCTATAATATATATAATCACTTAATCGTT
AAAATAATATAAAAAAGCAA

Downstream 100 bases:

>100_bases
AGGCGGTTATCCCGTCATTGCGAGCAGCCGTAGGCTTGCGCGGGCAATCTCATGAAATAATAAAATTCCTGAGATTGCCG
CGTCGAGGCTTTACCCCTCC

Product: protease activity modulator HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MLSKKYSSILKKSPWKDCDSNQDDNIFTRPRKNQFNFDKFQFQFNFNVKTIILAVVAVIALWLASGIYEIKEGDEAAVIR
FGRFVRKGYPGLNYHLPVPFEKIIVEKVKQSRRIEIGYRTNNSVRSGGDNTKNIAGESIMLTGDENIVALNCDVMWHINN
LEDFIFNVQRPAETVKATVESAVREVIGNTPISCVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVID
SYRDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYREEVISKAEGDSQRFNAIYKQYTVGRQVTRDRLYLE
VVEEILGGSNKTIINNALLPHMVIK

Sequences:

>Translated_345_residues
MLSKKYSSILKKSPWKDCDSNQDDNIFTRPRKNQFNFDKFQFQFNFNVKTIILAVVAVIALWLASGIYEIKEGDEAAVIR
FGRFVRKGYPGLNYHLPVPFEKIIVEKVKQSRRIEIGYRTNNSVRSGGDNTKNIAGESIMLTGDENIVALNCDVMWHINN
LEDFIFNVQRPAETVKATVESAVREVIGNTPISCVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVID
SYRDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYREEVISKAEGDSQRFNAIYKQYTVGRQVTRDRLYLE
VVEEILGGSNKTIINNALLPHMVIK
>Mature_345_residues
MLSKKYSSILKKSPWKDCDSNQDDNIFTRPRKNQFNFDKFQFQFNFNVKTIILAVVAVIALWLASGIYEIKEGDEAAVIR
FGRFVRKGYPGLNYHLPVPFEKIIVEKVKQSRRIEIGYRTNNSVRSGGDNTKNIAGESIMLTGDENIVALNCDVMWHINN
LEDFIFNVQRPAETVKATVESAVREVIGNTPISCVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVID
SYRDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYREEVISKAEGDSQRFNAIYKQYTVGRQVTRDRLYLE
VVEEILGGSNKTIINNALLPHMVIK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=280, Percent_Identity=28.2142857142857, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 39159; Mature: 39159

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKKYSSILKKSPWKDCDSNQDDNIFTRPRKNQFNFDKFQFQFNFNVKTIILAVVAVIA
CCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHH
LWLASGIYEIKEGDEAAVIRFGRFVRKGYPGLNYHLPVPFEKIIVEKVKQSRRIEIGYRT
HHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCEEEEEEC
NNSVRSGGDNTKNIAGESIMLTGDENIVALNCDVMWHINNLEDFIFNVQRPAETVKATVE
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCHHHHHHHCCCHHHHHHHHHH
SAVREVIGNTPISCVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVID
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCHHHHH
SYRDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYREEVISKAEGDSQRFN
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AIYKQYTVGRQVTRDRLYLEVVEEILGGSNKTIINNALLPHMVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHCC
>Mature Secondary Structure
MLSKKYSSILKKSPWKDCDSNQDDNIFTRPRKNQFNFDKFQFQFNFNVKTIILAVVAVIA
CCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHH
LWLASGIYEIKEGDEAAVIRFGRFVRKGYPGLNYHLPVPFEKIIVEKVKQSRRIEIGYRT
HHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCEEEEEEC
NNSVRSGGDNTKNIAGESIMLTGDENIVALNCDVMWHINNLEDFIFNVQRPAETVKATVE
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCHHHHHHHCCCHHHHHHHHHH
SAVREVIGNTPISCVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVID
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCHHHHH
SYRDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYREEVISKAEGDSQRFN
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AIYKQYTVGRQVTRDRLYLEVVEEILGGSNKTIINNALLPHMVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]