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The map label for this gene is aatA [H]

Identifier: 157825251

GI number: 157825251

Start: 120021

End: 121220

Strand: Reverse

Name: aatA [H]

Synonym: A1C_00650

Alternate gene names: 157825251

Gene position: 121220-120021 (Counterclockwise)

Preceding gene: 157825255

Following gene: 157825250

Centisome position: 9.85

GC content: 33.42

Gene sequence:

>1200_bases
ATGTCAATTATTTCTACAAGGCTAAATTCTATAAAGCCGTCACCAACCCTTGCAGTTGTAAAGAAAACCCTTGAACTTAA
AAAATCGGGAATTGATATTATTGCACTTGGTGCAGGTGAGCCTGATTTTGATACACCTGACAATATTAAGGAAGCGGCGA
TTAAAGCGATTCAAGACGGCTTTACTAAATATACTAACGTTGAGGGTATGCCTCTTTTAAAGCAAGCAATAAAAGACAAA
TTCAAACGTGAAAATAGTATAGATTACGAACTTGATGAAATAATAGTAAGTACCGGCGGTAAACAAGTTATATATAATTT
ATTTATGGCATCCTTAGATAAAGGGCATGAGGTAATTATTCCAGCACCCTATTGGGTTTCATATCCTGATATAGTTGCAC
TTAGCACAGGTACACCTGTTTTTGTAAATTGCGGAATTGAACATAACTTTAAATTAAGTGCAGAAGCTTTAGAACGTTCA
ATTACGGATAAAACTAAATGGCTTATTATTAACTCACCTAGTAATCCAACAGGTGCAAGCTATAACTTTGAAGAGCTAGA
AAATATTGCTAAAGTTTTAAGAAAATATCCTCATGTGAACGTAATGTCCGATGATATTTATGAACATATTATTTTTGATG
ATTTTAAATTTTATACATTAGCCCAAATAGCACCTGATTTAAAAGAGAGAATATTTACCGTAAACGGAGTATCTAAAGCT
TATTCTATGACAGGTTGGCGTATAGGCTACGGCGTGGGCTCTAAAACTTTAATTAAAGCAATGACTATTATTCAGTCTCA
AAGTACTTCAAACCCTTGTTCAATAAGTCAAATGGCTGCTATTGAAGCATTAAACGGTCCTCAAGATTATATAAAGCCTA
ATGCCTTAAATTTTCAAAAAAAGCGTGATTTTGCTTTATCAATTTTGAAAAGAGTAAAATATTTTGAGTGCTATAAGCCG
GAAGGTGCGTTTTACTTATTTGTTAAATGCGATAAAATATTGGGGCATAAAACTAGGTCAGGAAAAATAATTAGCAATAG
TAATGATTTTGCCGAATATTTACTTGAAGAAGCAAAAGTTGCAGTGGTACCCGGTATCGCTTTCGGATTAGAGGGTTATT
TTAGAATCTCTTATTCTACTTCTATGGAAGAGATAGAAGAAGCTTGTATGAGAATTGAGAGAGCTTGTAATGCTTTATAG

Upstream 100 bases:

>100_bases
CCCGAGGAAGCGGGCATCCAGTACTTTAACTCGCTTTACTCTGGATTCCTGCTGTCGCAGGAATGACATCAAACTACCTC
ATTAATACGGACTCAAAATT

Downstream 100 bases:

>100_bases
TACTAAGCTTGTCATACCGCAGCTTGACCGCGGTATCTAAAAAAAATAATATTAACAATGTAAATCTTTATATGGATACC
GCATTCAAGCCGCGGTATGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSIISTRLNSIKPSPTLAVVKKTLELKKSGIDIIALGAGEPDFDTPDNIKEAAIKAIQDGFTKYTNVEGMPLLKQAIKDK
FKRENSIDYELDEIIVSTGGKQVIYNLFMASLDKGHEVIIPAPYWVSYPDIVALSTGTPVFVNCGIEHNFKLSAEALERS
ITDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYPHVNVMSDDIYEHIIFDDFKFYTLAQIAPDLKERIFTVNGVSKA
YSMTGWRIGYGVGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNFQKKRDFALSILKRVKYFECYKP
EGAFYLFVKCDKILGHKTRSGKIISNSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYSTSMEEIEEACMRIERACNAL

Sequences:

>Translated_399_residues
MSIISTRLNSIKPSPTLAVVKKTLELKKSGIDIIALGAGEPDFDTPDNIKEAAIKAIQDGFTKYTNVEGMPLLKQAIKDK
FKRENSIDYELDEIIVSTGGKQVIYNLFMASLDKGHEVIIPAPYWVSYPDIVALSTGTPVFVNCGIEHNFKLSAEALERS
ITDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYPHVNVMSDDIYEHIIFDDFKFYTLAQIAPDLKERIFTVNGVSKA
YSMTGWRIGYGVGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNFQKKRDFALSILKRVKYFECYKP
EGAFYLFVKCDKILGHKTRSGKIISNSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYSTSMEEIEEACMRIERACNAL
>Mature_398_residues
SIISTRLNSIKPSPTLAVVKKTLELKKSGIDIIALGAGEPDFDTPDNIKEAAIKAIQDGFTKYTNVEGMPLLKQAIKDKF
KRENSIDYELDEIIVSTGGKQVIYNLFMASLDKGHEVIIPAPYWVSYPDIVALSTGTPVFVNCGIEHNFKLSAEALERSI
TDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYPHVNVMSDDIYEHIIFDDFKFYTLAQIAPDLKERIFTVNGVSKAY
SMTGWRIGYGVGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNFQKKRDFALSILKRVKYFECYKPE
GAFYLFVKCDKILGHKTRSGKIISNSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYSTSMEEIEEACMRIERACNAL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=343, Percent_Identity=28.2798833819242, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI169881279, Length=343, Percent_Identity=28.2798833819242, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI56713256, Length=367, Percent_Identity=27.5204359673025, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI56713254, Length=367, Percent_Identity=27.5204359673025, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI169881281, Length=339, Percent_Identity=24.4837758112094, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI149944424, Length=244, Percent_Identity=24.1803278688525, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1788722, Length=404, Percent_Identity=30.4455445544554, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=27.6923076923077, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=25.4742547425474, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=26.525198938992, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=361, Percent_Identity=26.0387811634349, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=361, Percent_Identity=26.0387811634349, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=357, Percent_Identity=27.4509803921569, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=365, Percent_Identity=26.027397260274, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320317, Length=358, Percent_Identity=24.3016759776536, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=359, Percent_Identity=23.9554317548747, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573069, Length=357, Percent_Identity=24.9299719887955, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=357, Percent_Identity=24.9299719887955, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=357, Percent_Identity=24.9299719887955, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=357, Percent_Identity=24.9299719887955, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=385, Percent_Identity=22.8571428571429, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24641770, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641760, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641768, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641766, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641764, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45551451, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44610; Mature: 44479

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIISTRLNSIKPSPTLAVVKKTLELKKSGIDIIALGAGEPDFDTPDNIKEAAIKAIQDG
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
FTKYTNVEGMPLLKQAIKDKFKRENSIDYELDEIIVSTGGKQVIYNLFMASLDKGHEVII
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
PAPYWVSYPDIVALSTGTPVFVNCGIEHNFKLSAEALERSITDKTKWLIINSPSNPTGAS
ECCCEECCCCEEEEECCCCEEEECCCCCCCEECHHHHHHHHCCCEEEEEEECCCCCCCCC
YNFEELENIAKVLRKYPHVNVMSDDIYEHIIFDDFKFYTLAQIAPDLKERIFTVNGVSKA
CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCHHHHHHHHHCHHHHHHEEEECCCHHH
YSMTGWRIGYGVGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNFQK
HHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCHH
KRDFALSILKRVKYFECYKPEGAFYLFVKCDKILGHKTRSGKIISNSNDFAEYLLEEAKV
HHHHHHHHHHHHHHHHEECCCCCEEEEEEECHHHCCCCCCCEEEECCCHHHHHHHHHCCE
AVVPGIAFGLEGYFRISYSTSMEEIEEACMRIERACNAL
EEECCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIISTRLNSIKPSPTLAVVKKTLELKKSGIDIIALGAGEPDFDTPDNIKEAAIKAIQDG
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
FTKYTNVEGMPLLKQAIKDKFKRENSIDYELDEIIVSTGGKQVIYNLFMASLDKGHEVII
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
PAPYWVSYPDIVALSTGTPVFVNCGIEHNFKLSAEALERSITDKTKWLIINSPSNPTGAS
ECCCEECCCCEEEEECCCCEEEECCCCCCCEECHHHHHHHHCCCEEEEEEECCCCCCCCC
YNFEELENIAKVLRKYPHVNVMSDDIYEHIIFDDFKFYTLAQIAPDLKERIFTVNGVSKA
CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCHHHHHHHHHCHHHHHHEEEECCCHHH
YSMTGWRIGYGVGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNFQK
HHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCHH
KRDFALSILKRVKYFECYKPEGAFYLFVKCDKILGHKTRSGKIISNSNDFAEYLLEEAKV
HHHHHHHHHHHHHHHHEECCCCCEEEEEEECHHHCCCCCCCEEEECCCHHHHHHHHHCCE
AVVPGIAFGLEGYFRISYSTSMEEIEEACMRIERACNAL
EEECCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA