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The map label for this gene is waaA [H]

Identifier: 157825249

GI number: 157825249

Start: 117994

End: 119250

Strand: Reverse

Name: waaA [H]

Synonym: A1C_00640

Alternate gene names: 157825249

Gene position: 119250-117994 (Counterclockwise)

Preceding gene: 157825250

Following gene: 157825248

Centisome position: 9.69

GC content: 31.74

Gene sequence:

>1257_bases
ATGATGTTATTATATTATGCTTTAAGCTTTATATTATTGCCTGTTTATTTTATCATAATTATTATACGCTTATTAATAGG
TAAAGAAGATATAAGACGCATCCAAGAACGTTTTGCTATAGGTAAGTATCGACAAGACAACTCCTTCTTAATATGGATCC
ATGCAGCTAGCGTCGGTGAGTCTATGGCAGCTTTAACATTAATATATAATATAAGTAAACGCTATCCTAAAATTCGTTTT
TTAGTAACTTCTTGGACTAACAGCTCCGCTAAAATATTAACTGCCAAATTACCTAAAATAGCAGTTCACCAATTTTTACC
GATAGATAATATTATTTTTACTCGAAAATTTTTAAAAAATTGGCAACCTAATTTAGGTATTTTTATAGAATCGGAATTAT
GGCCGTGTACTATTAATGAAGGAGCAAGGCAGTTTAAATTGCTGTTAGTTAATGCACGTATTTCCGATAAATCATTTAAA
GCTTGGCTAAAAAGAAAAAGCTTCTTTCAGCTTATCATCAAACATTTTAGTAAAATTATTGTGCAAAGCGAGCGTGACTT
ACAAAAATTCAATGAACTTGGCGTATCAGATGCAATTAATTTAGGCAATATTAAATTTGCCAATGAAAAACTTCCAGTGA
ATCAAGAAGAGTTATCAAAATTAATCTCACATTTAGACAATAGACAAGTGTTGGTATTTGCTAGCACTCACCATGAAGAT
GAAGAGGTGATTTTACCAATAATCAAAAACCTACAAGAGCAGTGTTTAGATTGCTATATTATCCTAATTCCAAGACATCC
CGAGCGAGTTAAATCCATTATCGATAATTGTAAATCACATAATTTATCCGCCACCGCTAAGTCACAAAATGATTTACCTG
TTTTAAGCAATGATATTTATATAGTTGATAGATTCGGCGAAATGGGATTATTTTTTTCCGTAGCTACAATTTCTTTTATC
GGCGGTTCTTTTAAACAAGGCGGACATAATATTTTAGAAGCGGCATATTTCTCTAATTGTATTATATTCGGTCCCGATAT
GAGTAAAAACACCGATATCGCTAAAGGCGTACTGCAAAATGAAGCAGCTATCCAAATCAAAAATGGTGAAGATTTACTCA
CCAAACTAACATATCTCCTTAACCCTAATAATTCTCTAGAACTTAAAGCTTATCGTGAAAAAGCTTTTAAATTTGTTGAG
AATAACCAAAAAGTCCTAGATGAATATTTAAAGGTCATTACGAAGTTTCTGCCATAG

Upstream 100 bases:

>100_bases
AAATCATAGTTGGCTCACCTTTAGAACTCACAAATGATAAAATACAAAACCATATAAGCCTTGAACAACAACTAACAAGC
TTAACAGAGAGCTTAAAGAA

Downstream 100 bases:

>100_bases
CTAAGGTTAGTTAATAAAAGTAGAATTTTCAAAAATAAAATTTAACTTTTGATTGTTATATGATTAAATAGCTATTTAAT
CATGAAGGATATAATTATGC

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MMLLYYALSFILLPVYFIIIIIRLLIGKEDIRRIQERFAIGKYRQDNSFLIWIHAASVGESMAALTLIYNISKRYPKIRF
LVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLKNWQPNLGIFIESELWPCTINEGARQFKLLLVNARISDKSFK
AWLKRKSFFQLIIKHFSKIIVQSERDLQKFNELGVSDAINLGNIKFANEKLPVNQEELSKLISHLDNRQVLVFASTHHED
EEVILPIIKNLQEQCLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSNDIYIVDRFGEMGLFFSVATISFI
GGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLLTKLTYLLNPNNSLELKAYREKAFKFVE
NNQKVLDEYLKVITKFLP

Sequences:

>Translated_418_residues
MMLLYYALSFILLPVYFIIIIIRLLIGKEDIRRIQERFAIGKYRQDNSFLIWIHAASVGESMAALTLIYNISKRYPKIRF
LVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLKNWQPNLGIFIESELWPCTINEGARQFKLLLVNARISDKSFK
AWLKRKSFFQLIIKHFSKIIVQSERDLQKFNELGVSDAINLGNIKFANEKLPVNQEELSKLISHLDNRQVLVFASTHHED
EEVILPIIKNLQEQCLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSNDIYIVDRFGEMGLFFSVATISFI
GGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLLTKLTYLLNPNNSLELKAYREKAFKFVE
NNQKVLDEYLKVITKFLP
>Mature_418_residues
MMLLYYALSFILLPVYFIIIIIRLLIGKEDIRRIQERFAIGKYRQDNSFLIWIHAASVGESMAALTLIYNISKRYPKIRF
LVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLKNWQPNLGIFIESELWPCTINEGARQFKLLLVNARISDKSFK
AWLKRKSFFQLIIKHFSKIIVQSERDLQKFNELGVSDAINLGNIKFANEKLPVNQEELSKLISHLDNRQVLVFASTHHED
EEVILPIIKNLQEQCLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSNDIYIVDRFGEMGLFFSVATISFI
GGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLLTKLTYLLNPNNSLELKAYREKAFKFVE
NNQKVLDEYLKVITKFLP

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=425, Percent_Identity=28.7058823529412, Blast_Score=185, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507
- InterPro:   IPR005728 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 48060; Mature: 48060

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLLYYALSFILLPVYFIIIIIRLLIGKEDIRRIQERFAIGKYRQDNSFLIWIHAASVGE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCC
SMAALTLIYNISKRYPKIRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLKN
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHC
WQPNLGIFIESELWPCTINEGARQFKLLLVNARISDKSFKAWLKRKSFFQLIIKHFSKII
CCCCCCEEEECCCCCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQSERDLQKFNELGVSDAINLGNIKFANEKLPVNQEELSKLISHLDNRQVLVFASTHHED
HCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
EEVILPIIKNLQEQCLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSNDIY
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEE
IVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQN
EEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCC
EAAIQIKNGEDLLTKLTYLLNPNNSLELKAYREKAFKFVENNQKVLDEYLKVITKFLP
CCEEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMLLYYALSFILLPVYFIIIIIRLLIGKEDIRRIQERFAIGKYRQDNSFLIWIHAASVGE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCC
SMAALTLIYNISKRYPKIRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLKN
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHC
WQPNLGIFIESELWPCTINEGARQFKLLLVNARISDKSFKAWLKRKSFFQLIIKHFSKII
CCCCCCEEEECCCCCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQSERDLQKFNELGVSDAINLGNIKFANEKLPVNQEELSKLISHLDNRQVLVFASTHHED
HCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
EEVILPIIKNLQEQCLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSNDIY
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEE
IVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQN
EEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCC
EAAIQIKNGEDLLTKLTYLLNPNNSLELKAYREKAFKFVENNQKVLDEYLKVITKFLP
CCEEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]