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The map label for this gene is clpB [H]

Identifier: 157825138

GI number: 157825138

Start: 10272

End: 12848

Strand: Reverse

Name: clpB [H]

Synonym: A1C_00065

Alternate gene names: 157825138

Gene position: 12848-10272 (Counterclockwise)

Preceding gene: 157825147

Following gene: 157825137

Centisome position: 1.04

GC content: 36.94

Gene sequence:

>2577_bases
ATGAATATTGATAAATTTACTGCACATGCTAAATCAGTGATAGCTCGTAGCCAATCGATTGCTGCTAAAAACGATCATCA
GCAAATATTATCTTTGCATTTATTATCTAGTCTTTTAAGTGAAGAAACAGGTATAATTCGAACCATTATTAATAATACCG
GCGGTAATATAAACTTATTAGAAGATCAAGTGCAGCTAGCACTAAATAAAATCCCAAAAGTTCAGGTTGAGGGAGTGGGA
CAAGTTTATTCTTCTGCTGAAGCTCTTAAAGTTTTAGAAAAAGCTAGTAACATTGCTAAAGACAGTGGGGATAGCTTTGT
AACCATAGAGCGTATATTTGAAGCATTAACTTATGATAATACTATAGCCGGTAAAATTTTAACGAATAATGGAATTAATA
GTAAAAAATTAGCAGCAGTTATTTTACAGCTTCGTAAAGGCAAAAAAGCAGATACCGAATCAGCAGAAAATAGTTACGAT
GCTCTAAAGAAATATGGCAGAGATGTGACAGAGCTTGCCGAAAGCGGTAAGCTTGACCCGATAATCGGACGTGATGAAGA
AATAAGAAGAACAGTGCAGGTACTATCACGACGTATGAAAAATAACCCTGTATTGATCGGCGAGCCCGGAGTCGGTAAAA
CTGCTATAATAGAGGGGCTTGCACAACGTATATTTAGTAAGGACGTACCTGAGTCGCTTATGAATTGCCGTATTATTGAG
CTTGATATTGGAGCATTAATAGCAGGTGCTAAATATCGAGGTGAATTTGAGGAGCGTCTTAAAGCAGTACTTAGTGAAAT
CAAAGACTCAAGCGGTGAAATTATTTTATTTATCGATGAATTGCATCTATTAGTCGGTACGGGAAAAACCGACGGTGCTA
TGGATGCCTCGAATTTACTAAAGCCAATGCTTGCTCGTGGTGAGCTGCACTGTATCGGTGCTACTACTCTAGACGAATAT
CGTAAATATATCGAGAAAGATGCAGCACTTGCTCGCCGTTTCCAGCCTGTTTACGTGAGTGAGCCGACGGTTGAGGATAC
TATATCAATACTTAGAGGCATTAAAGAAAAATACGAGCTGCATCATGCAGTGCGAATTTCCGATAGTGCGATAGTTTCAG
CAGCGACGTTATCAAACCGTTATATTACCGATCGTTATTTACCTGATAAAGCTATCGATTTGATTGATGAAGCTTGTAGC
CGTATGAAAATAGAATTGTCAAGTAAGCCTGAAGAGCTGGACGAGCTAGATCGCCGTATTATTCAGATAAAAATTGAGCT
TGCAGCACTTAAAAAAGAAAATGACGAGCATTCTAAAAAGAAAATTACACATTTAACCGAGGAACTCGAAAAATTAGAAT
CTAAATCATATGATATGAACGCTAAATGGCATGCAGAAAAGTCTAAACTACAGCAAGCCCAAAAACTTAAAGAAGAGTTA
GAACGAGCAAGAATCAATCTAGAGCGTGCCGAGCGTGACTCTAATCTCGCTAAAGCTAGTGAGCTAAAATATGGAATTAT
ACCTGAGATTATGAAAAAGATTCAGGAAGCCGAAAGTATGGATAATAAAGGGCTATTAAAAGAAATTGTATCGGAAAGCG
ATATAGCAAGTATTATCTCTCGTATCACTGGTATTCCAATTGATACGATGCTATCAAGTGAGCGTGAGCGTCTACTTGTG
ATGGAGAAGAAACTACGTGAATCGGTCATAGGACAAGATGAAGCAATTAAAGGGGTCAGTGATGCAGTTAGAAGATCACG
TGCAGGTATTCAGGATATTAACCGCCCTCTTGGTTCATTTTTATTCTTAGGACAGACAGGAGTTGGTAAAACTGAGCTTA
CCAAAGCCTTAGCCGGTTTTCTTTTTGATGACCGTAACGCGATACTTCGTATAGATATGTCGGAATATATGGAGAAGCAC
GCTATTTCTCGTCTGATAGGAGCTCCTCCAGGCTATATAGGATATGATCAAGGTGGAGTGCTAACAGAGGCAGTAAGACG
CCGCCCATATCAGGTAATATTATTTGATGAGGTTGAAAAAGCCCACCACGATATATTTAATATTATGCTGCAAATACTTG
ATGAAGGAAGATTAACCGATAGTCAGGGTATCACAGTTGATTTTAAAAATACTATTATAGTTTTAACTTCTAATTTAGGT
GCTGAGATACTCATTAATCAGAAAGAGGACGAAGATACATATAAAGTAAAAGATGAGGTTATGGAATATGTAAAAGAAGT
ATTTAAGCCGGAGTTTCTTAATAGGTTAGATGAAATTATATTATTCCATCGGCTAAATCATAATGATATTCATGATATAG
TTAAGATACAGCTTGGAAGCTTAAAAAAAATTTTGCTACAACAAAATATTATTCTTGAATTTGATGAATCTGCTTTAAAT
TATTTAGCCGAAAAAGGCTATGATCGAAGTTTTGGAGCAAGACCCTTAAAACGCCTTATCCAGAGGGAAATACAAAATAA
TTTAGCCAAGATGATTTTAGCAGGCGAAATAAGTAGCGGTAATATCGTGAAAATAGGTAGAGAAAAGGAAGAGCTAAGGA
TAAAGATAATTGATTAA

Upstream 100 bases:

>100_bases
TATGTATTTGTTCATCTCTTGTTATTTTAATTAAAAATTATTATATGAAAATAGTCTAGTTAAAAATATTTAACTTTATT
AATCAAAATATGTTATTTAT

Downstream 100 bases:

>100_bases
GCTCTGCGTACGAAAACTAAATTATTGCATAATTCATAATGTTAATTAATTTTTCTTGAGTCTAGTCTATTACTTTATTA
TAAATATCCTTCTAACTTTG

Product: clpB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 858; Mature: 858

Protein sequence:

>858_residues
MNIDKFTAHAKSVIARSQSIAAKNDHQQILSLHLLSSLLSEETGIIRTIINNTGGNINLLEDQVQLALNKIPKVQVEGVG
QVYSSAEALKVLEKASNIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINSKKLAAVILQLRKGKKADTESAENSYD
ALKKYGRDVTELAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLMNCRIIE
LDIGALIAGAKYRGEFEERLKAVLSEIKDSSGEIILFIDELHLLVGTGKTDGAMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVSAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKITHLTEELEKLESKSYDMNAKWHAEKSKLQQAQKLKEEL
ERARINLERAERDSNLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEKKLRESVIGQDEAIKGVSDAVRRSRAGIQDINRPLGSFLFLGQTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHHDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEILINQKEDEDTYKVKDEVMEYVKEVFKPEFLNRLDEIILFHRLNHNDIHDIVKIQLGSLKKILLQQNIILEFDESALN
YLAEKGYDRSFGARPLKRLIQREIQNNLAKMILAGEISSGNIVKIGREKEELRIKIID

Sequences:

>Translated_858_residues
MNIDKFTAHAKSVIARSQSIAAKNDHQQILSLHLLSSLLSEETGIIRTIINNTGGNINLLEDQVQLALNKIPKVQVEGVG
QVYSSAEALKVLEKASNIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINSKKLAAVILQLRKGKKADTESAENSYD
ALKKYGRDVTELAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLMNCRIIE
LDIGALIAGAKYRGEFEERLKAVLSEIKDSSGEIILFIDELHLLVGTGKTDGAMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVSAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKITHLTEELEKLESKSYDMNAKWHAEKSKLQQAQKLKEEL
ERARINLERAERDSNLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEKKLRESVIGQDEAIKGVSDAVRRSRAGIQDINRPLGSFLFLGQTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHHDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEILINQKEDEDTYKVKDEVMEYVKEVFKPEFLNRLDEIILFHRLNHNDIHDIVKIQLGSLKKILLQQNIILEFDESALN
YLAEKGYDRSFGARPLKRLIQREIQNNLAKMILAGEISSGNIVKIGREKEELRIKIID
>Mature_858_residues
MNIDKFTAHAKSVIARSQSIAAKNDHQQILSLHLLSSLLSEETGIIRTIINNTGGNINLLEDQVQLALNKIPKVQVEGVG
QVYSSAEALKVLEKASNIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINSKKLAAVILQLRKGKKADTESAENSYD
ALKKYGRDVTELAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLMNCRIIE
LDIGALIAGAKYRGEFEERLKAVLSEIKDSSGEIILFIDELHLLVGTGKTDGAMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVSAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKITHLTEELEKLESKSYDMNAKWHAEKSKLQQAQKLKEEL
ERARINLERAERDSNLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEKKLRESVIGQDEAIKGVSDAVRRSRAGIQDINRPLGSFLFLGQTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHHDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEILINQKEDEDTYKVKDEVMEYVKEVFKPEFLNRLDEIILFHRLNHNDIHDIVKIQLGSLKKILLQQNIILEFDESALN
YLAEKGYDRSFGARPLKRLIQREIQNNLAKMILAGEISSGNIVKIGREKEELRIKIID

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=315, Percent_Identity=35.2380952380952, Blast_Score=201, Evalue=2e-51,
Organism=Escherichia coli, GI1788943, Length=848, Percent_Identity=55.188679245283, Blast_Score=951, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=332, Percent_Identity=44.8795180722892, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=692, Percent_Identity=53.9017341040462, Blast_Score=774, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=866, Percent_Identity=43.3025404157044, Blast_Score=676, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96438; Mature: 96438

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDKFTAHAKSVIARSQSIAAKNDHQQILSLHLLSSLLSEETGIIRTIINNTGGNINLL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEH
EDQVQLALNKIPKVQVEGVGQVYSSAEALKVLEKASNIAKDSGDSFVTIERIFEALTYDN
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
TIAGKILTNNGINSKKLAAVILQLRKGKKADTESAENSYDALKKYGRDVTELAESGKLDP
CEECEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHCCHHHHHHHCCCCCC
IIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLMNCRIIE
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEE
LDIGALIAGAKYRGEFEERLKAVLSEIKDSSGEIILFIDELHLLVGTGKTDGAMDASNLL
EEHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHH
KPMLARGELHCIGATTLDEYRKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYEL
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
HHAVRISDSAIVSAATLSNRYITDRYLPDKAIDLIDEACSRMKIELSSKPEELDELDRRI
HHHHEECCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHH
IQIKIELAALKKENDEHSKKKITHLTEELEKLESKSYDMNAKWHAEKSKLQQAQKLKEEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ERARINLERAERDSNLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIIS
HHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
RITGIPIDTMLSSERERLLVMEKKLRESVIGQDEAIKGVSDAVRRSRAGIQDINRPLGSF
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHE
LFLGQTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKHAISRLIGAPPGYIGYDQGGV
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYQVILFDEVEKAHHDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCC
AEILINQKEDEDTYKVKDEVMEYVKEVFKPEFLNRLDEIILFHRLNHNDIHDIVKIQLGS
CEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LKKILLQQNIILEFDESALNYLAEKGYDRSFGARPLKRLIQREIQNNLAKMILAGEISSG
HHHHHHHCCHHEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCC
NIVKIGREKEELRIKIID
CEEEECCCCCEEEEEECC
>Mature Secondary Structure
MNIDKFTAHAKSVIARSQSIAAKNDHQQILSLHLLSSLLSEETGIIRTIINNTGGNINLL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEH
EDQVQLALNKIPKVQVEGVGQVYSSAEALKVLEKASNIAKDSGDSFVTIERIFEALTYDN
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
TIAGKILTNNGINSKKLAAVILQLRKGKKADTESAENSYDALKKYGRDVTELAESGKLDP
CEECEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHCCHHHHHHHCCCCCC
IIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLMNCRIIE
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEE
LDIGALIAGAKYRGEFEERLKAVLSEIKDSSGEIILFIDELHLLVGTGKTDGAMDASNLL
EEHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHH
KPMLARGELHCIGATTLDEYRKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYEL
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
HHAVRISDSAIVSAATLSNRYITDRYLPDKAIDLIDEACSRMKIELSSKPEELDELDRRI
HHHHEECCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHH
IQIKIELAALKKENDEHSKKKITHLTEELEKLESKSYDMNAKWHAEKSKLQQAQKLKEEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ERARINLERAERDSNLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIIS
HHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
RITGIPIDTMLSSERERLLVMEKKLRESVIGQDEAIKGVSDAVRRSRAGIQDINRPLGSF
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHE
LFLGQTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKHAISRLIGAPPGYIGYDQGGV
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYQVILFDEVEKAHHDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCC
AEILINQKEDEDTYKVKDEVMEYVKEVFKPEFLNRLDEIILFHRLNHNDIHDIVKIQLGS
CEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LKKILLQQNIILEFDESALNYLAEKGYDRSFGARPLKRLIQREIQNNLAKMILAGEISSG
HHHHHHHCCHHEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCC
NIVKIGREKEELRIKIID
CEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]