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The map label for this gene is zntR [H]

Identifier: 157372750

GI number: 157372750

Start: 5008979

End: 5009410

Strand: Reverse

Name: zntR [H]

Synonym: Spro_4517

Alternate gene names: 157372750

Gene position: 5009410-5008979 (Counterclockwise)

Preceding gene: 157372751

Following gene: 157372749

Centisome position: 91.94

GC content: 49.07

Gene sequence:

>432_bases
ATGCTTAAAATTGGCCAACTGGCAAAACTTGCTGACGTGACCCCTGACACCGTGCGTTACTACGAGAAGCAGGGAATGAT
GGATCATAACATCCGTACCGAGGGCGGTTATCGGTTGTATAGTCAGCAAGACTTGCAGCGGTTACGTTTTATCCGCTATG
CCAAACAACTCGGTTTTACATTGGAAACCATTGCTGAACTATTATCTATCCGGGTTGATCCTGTACATCATACCTGTCGG
GAGTCGAAGTCGATCGTCGATGCACGGCTCAGTGAAGTAGAGAATAAGCTTAAAGAGCTGACCCGGATGCGTGAGTCGCT
AAAGCGCCTCAGCGATGCTTGCTGCGGTAGCGCGCATACCAGCAATTATTGCTCGATTTTGGAAGCGCTGGAACAGGGGG
CCAGTGATGAAAAGGCAAAAAAAGATGCCTGA

Upstream 100 bases:

>100_bases
TCTCTATCCGCTATGCTAACGCTATTAACATGAGTACCGATTTCTTGCATGGTGAATATCAACGTGCACTGAGTGGAAAA
TTTTCACCGGAGAAAGAGTG

Downstream 100 bases:

>100_bases
AAGGGCTGGCGGCTCTTTAATTTTTACACGGGCAGCAGTATTATCGCCGTGATTTATATCCATACATAAACAAGGAGAAT
TACCATGACTAAATACCGTC

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MLKIGQLAKLADVTPDTVRYYEKQGMMDHNIRTEGGYRLYSQQDLQRLRFIRYAKQLGFTLETIAELLSIRVDPVHHTCR
ESKSIVDARLSEVENKLKELTRMRESLKRLSDACCGSAHTSNYCSILEALEQGASDEKAKKDA

Sequences:

>Translated_143_residues
MLKIGQLAKLADVTPDTVRYYEKQGMMDHNIRTEGGYRLYSQQDLQRLRFIRYAKQLGFTLETIAELLSIRVDPVHHTCR
ESKSIVDARLSEVENKLKELTRMRESLKRLSDACCGSAHTSNYCSILEALEQGASDEKAKKDA
>Mature_143_residues
MLKIGQLAKLADVTPDTVRYYEKQGMMDHNIRTEGGYRLYSQQDLQRLRFIRYAKQLGFTLETIAELLSIRVDPVHHTCR
ESKSIVDARLSEVENKLKELTRMRESLKRLSDACCGSAHTSNYCSILEALEQGASDEKAKKDA

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=139, Percent_Identity=69.0647482014388, Blast_Score=211, Evalue=1e-56,
Organism=Escherichia coli, GI1786695, Length=129, Percent_Identity=35.6589147286822, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16339; Mature: 16339

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGQLAKLADVTPDTVRYYEKQGMMDHNIRTEGGYRLYSQQDLQRLRFIRYAKQLGFT
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCH
LETIAELLSIRVDPVHHTCRESKSIVDARLSEVENKLKELTRMRESLKRLSDACCGSAHT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SNYCSILEALEQGASDEKAKKDA
HHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MLKIGQLAKLADVTPDTVRYYEKQGMMDHNIRTEGGYRLYSQQDLQRLRFIRYAKQLGFT
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCH
LETIAELLSIRVDPVHHTCRESKSIVDARLSEVENKLKELTRMRESLKRLSDACCGSAHT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SNYCSILEALEQGASDEKAKKDA
HHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]