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The map label for this gene is lamB

Identifier: 157372702

GI number: 157372702

Start: 4942015

End: 4943319

Strand: Reverse

Name: lamB

Synonym: Spro_4469

Alternate gene names: 157372702

Gene position: 4943319-4942015 (Counterclockwise)

Preceding gene: 157372703

Following gene: 157372701

Centisome position: 90.72

GC content: 56.93

Gene sequence:

>1305_bases
ATGATGACTACTCTGCGCAAACTTCCTCTGGCACTGGCAATCGCCGCTGGTGTTCTCACCACTCAGGCCATGGCCGTTGA
TTTTAAAGGCTATGCCCGTTCCGGCATCGGCTGGACCGGCAGTGGCGGTGAGCAACAGTGCTTCAAGGCCACCGGCGCCG
ACAGCAAATACCGTCTCGGTAACGAATGTGAAACCTACGCCGAACTGAAGCTGGGTCAGGAAGTGTGGAAAGAGGGCGAC
AAAAGCTTCTACTTCGATACCAACCTGGCTTACTCGGTTTCACAACGTTCCGACTGGGAAGACGTGACGCCAGGCTTCCG
TGAAGTGAACGTGCAGGGTAAAAACCTGATCGAATGGCTGCCGGGGGCCAATATGTGGGCCGGTAAGCGCTTCTATCAGC
GTCATGATGTTCACATGATTGACTTCTACTACTGGGATATCTCAGGTCCGGGTGCCGGTCTGGAAAATATCGATCTGGGC
TTCGGCAAGCTGTCTGCTGCCGTGACCCGTAACTCCGAATCCGGCGGTTCTTACGGTTATCTGGATAATGAACTGGACCA
ACGTCCGACCGTCAACGACACCTTCGACGTGCGTCTGGCCGGTCTGGAATTGAACCCGGGCGGTACCCTGGAGCTGGGGC
TGGACTACGGTCGGGCTAACGCGCAGGACGGTTACAGCCTGGCCGATGGCGCCAGCAAAGACGGTTGGTTGGTGACTGCG
GAACATACCCAGAGCATCCTGACCGGCTACAACAAGTTCGTGCTGCAATACGCCACAGATTCGATGACCTCGCAGAACAA
CGGCCGTAACCAGGGGTCAACCATCGACAACAACGGCAAGATGATCCGCGTGCTGGATCACGGTGCCATCGACTTCAACG
ATCAATGGGCGATGATGTATGTCGCCATGTTCCAGGACATCGATCGCGACAACAACAACGGCAGCACCTGGTACACCGTG
GGCGTGCGCCCAATGTACAAATGGACGCCTATCATGAGCACCCTGCTGGAAGCCGGTTACGACAACGTGAAATCCCAGCG
CACTGGCGATCGCAACGGCCAGTACAAGGTCACCCTGGCGCAACAGTGGCAGGCGGGCAACAGCATCTGGTCACGTCCGG
CTATCCGCGTATTTGCGACCTACGCCAAGTGGGATGAGAAATGGGGCTACGCGACTTCCAGCGACGCAGAGGGCAATCCA
GGTCTGAAAGCCGGCACCGCGTATAACGACACCAGCATGCATACCTTCAGCCGTGGCAATGACGATGAAGTCACCTTCGG
CGCCCAGATGGAAATCTGGTGGTAA

Upstream 100 bases:

>100_bases
CTCACCGCTGCCATCTGTTCCGTGAAGACGGTACGGCATGTAAACGGCTGCACCAGGAGCCGGGCGTTTAAAGCATCACA
GTCTGTATAACAGGAGAATA

Downstream 100 bases:

>100_bases
TGAGATAACGGGGAGAGCCAGGTGCTCTCCCCAACCTGTATTCGCCGACATCGTCTCTCTTGCCTGAGCCGCGTCGGTTA
CCTTGGGGTATAACAATGAA

Product: maltoporin

Products: NA

Alternate protein names: Maltose-inducible porin

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MMTTLRKLPLALAIAAGVLTTQAMAVDFKGYARSGIGWTGSGGEQQCFKATGADSKYRLGNECETYAELKLGQEVWKEGD
KSFYFDTNLAYSVSQRSDWEDVTPGFREVNVQGKNLIEWLPGANMWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDLG
FGKLSAAVTRNSESGGSYGYLDNELDQRPTVNDTFDVRLAGLELNPGGTLELGLDYGRANAQDGYSLADGASKDGWLVTA
EHTQSILTGYNKFVLQYATDSMTSQNNGRNQGSTIDNNGKMIRVLDHGAIDFNDQWAMMYVAMFQDIDRDNNNGSTWYTV
GVRPMYKWTPIMSTLLEAGYDNVKSQRTGDRNGQYKVTLAQQWQAGNSIWSRPAIRVFATYAKWDEKWGYATSSDAEGNP
GLKAGTAYNDTSMHTFSRGNDDEVTFGAQMEIWW

Sequences:

>Translated_434_residues
MMTTLRKLPLALAIAAGVLTTQAMAVDFKGYARSGIGWTGSGGEQQCFKATGADSKYRLGNECETYAELKLGQEVWKEGD
KSFYFDTNLAYSVSQRSDWEDVTPGFREVNVQGKNLIEWLPGANMWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDLG
FGKLSAAVTRNSESGGSYGYLDNELDQRPTVNDTFDVRLAGLELNPGGTLELGLDYGRANAQDGYSLADGASKDGWLVTA
EHTQSILTGYNKFVLQYATDSMTSQNNGRNQGSTIDNNGKMIRVLDHGAIDFNDQWAMMYVAMFQDIDRDNNNGSTWYTV
GVRPMYKWTPIMSTLLEAGYDNVKSQRTGDRNGQYKVTLAQQWQAGNSIWSRPAIRVFATYAKWDEKWGYATSSDAEGNP
GLKAGTAYNDTSMHTFSRGNDDEVTFGAQMEIWW
>Mature_434_residues
MMTTLRKLPLALAIAAGVLTTQAMAVDFKGYARSGIGWTGSGGEQQCFKATGADSKYRLGNECETYAELKLGQEVWKEGD
KSFYFDTNLAYSVSQRSDWEDVTPGFREVNVQGKNLIEWLPGANMWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDLG
FGKLSAAVTRNSESGGSYGYLDNELDQRPTVNDTFDVRLAGLELNPGGTLELGLDYGRANAQDGYSLADGASKDGWLVTA
EHTQSILTGYNKFVLQYATDSMTSQNNGRNQGSTIDNNGKMIRVLDHGAIDFNDQWAMMYVAMFQDIDRDNNNGSTWYTV
GVRPMYKWTPIMSTLLEAGYDNVKSQRTGDRNGQYKVTLAQQWQAGNSIWSRPAIRVFATYAKWDEKWGYATSSDAEGNP
GLKAGTAYNDTSMHTFSRGNDDEVTFGAQMEIWW

Specific function: Involved in the transport of maltose and maltodextrins

COG id: COG4580

COG function: function code G; Maltoporin (phage lambda and maltose receptor)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the porin LamB (TC 1.B.3) family

Homologues:

Organism=Escherichia coli, GI1790469, Length=448, Percent_Identity=72.7678571428571, Blast_Score=671, Evalue=0.0,
Organism=Escherichia coli, GI1790157, Length=458, Percent_Identity=27.5109170305677, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LAMB_SERP5 (A8GKC3)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480691.1
- ProteinModelPortal:   A8GKC3
- SMR:   A8GKC3
- STRING:   A8GKC3
- GeneID:   5602513
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4469
- eggNOG:   COG4580
- HOGENOM:   HBG309714
- OMA:   AVTRNTE
- ProtClustDB:   PRK09360
- BioCyc:   SPRO399741:SPRO_4469-MONOMER
- HAMAP:   MF_01301
- InterPro:   IPR003192
- Gene3D:   G3DSA:2.40.170.10
- ProDom:   PD008788

Pfam domain/function: PF02264 LamB

EC number: NA

Molecular weight: Translated: 48347; Mature: 48347

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTLRKLPLALAIAAGVLTTQAMAVDFKGYARSGIGWTGSGGEQQCFKATGADSKYRLG
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHCCCCCCCCCCCCHHHHHHCCCCCCCCCC
NECETYAELKLGQEVWKEGDKSFYFDTNLAYSVSQRSDWEDVTPGFREVNVQGKNLIEWL
CHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHC
PGANMWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDLGFGKLSAAVTRNSESGGSYGY
CCCCCCCCHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCC
LDNELDQRPTVNDTFDVRLAGLELNPGGTLELGLDYGRANAQDGYSLADGASKDGWLVTA
CCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCEECCCCCCCCEEEEH
EHTQSILTGYNKFVLQYATDSMTSQNNGRNQGSTIDNNGKMIRVLDHGAIDFNDQWAMMY
HHHHHHHHHHHHEEEEEHHHHHCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCHHHHH
VAMFQDIDRDNNNGSTWYTVGVRPMYKWTPIMSTLLEAGYDNVKSQRTGDRNGQYKVTLA
HHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEE
QQWQAGNSIWSRPAIRVFATYAKWDEKWGYATSSDAEGNPGLKAGTAYNDTSMHTFSRGN
ECCCCCCCHHCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
DDEVTFGAQMEIWW
CCCEEEEEEEEEEC
>Mature Secondary Structure
MMTTLRKLPLALAIAAGVLTTQAMAVDFKGYARSGIGWTGSGGEQQCFKATGADSKYRLG
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHCCCCCCCCCCCCHHHHHHCCCCCCCCCC
NECETYAELKLGQEVWKEGDKSFYFDTNLAYSVSQRSDWEDVTPGFREVNVQGKNLIEWL
CHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHC
PGANMWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDLGFGKLSAAVTRNSESGGSYGY
CCCCCCCCHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCC
LDNELDQRPTVNDTFDVRLAGLELNPGGTLELGLDYGRANAQDGYSLADGASKDGWLVTA
CCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCEECCCCCCCCEEEEH
EHTQSILTGYNKFVLQYATDSMTSQNNGRNQGSTIDNNGKMIRVLDHGAIDFNDQWAMMY
HHHHHHHHHHHHEEEEEHHHHHCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCHHHHH
VAMFQDIDRDNNNGSTWYTVGVRPMYKWTPIMSTLLEAGYDNVKSQRTGDRNGQYKVTLA
HHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEE
QQWQAGNSIWSRPAIRVFATYAKWDEKWGYATSSDAEGNPGLKAGTAYNDTSMHTFSRGN
ECCCCCCCHHCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
DDEVTFGAQMEIWW
CCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA