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The map label for this gene is ubiC

Identifier: 157372697

GI number: 157372697

Start: 4936619

End: 4937143

Strand: Reverse

Name: ubiC

Synonym: Spro_4464

Alternate gene names: 157372697

Gene position: 4937143-4936619 (Counterclockwise)

Preceding gene: 157372701

Following gene: 157372696

Centisome position: 90.61

GC content: 59.81

Gene sequence:

>525_bases
ATGTCAGGCAATAGGGATTCGATCCTACCGCCGCTGGAGTGGCTATCCGCGCAACATCCTCCGGCACCCGCCGCCGTCAG
CGATTGGCTGATGGAACCAGGTTCCATGACGCGCCGCTTTGAACGCCACTGTGGGCGGGTGCACGTCGAACCGCAGCGCG
AATGTTTTGTTACCCGCGACCAACTGGGGGAAGAGGCAGAACACCTGCCGGACAGTCCGCGCTATTGGCTGCGTGAAGTT
GTGTTGTTGGGCGATAACCAGCCCTGGCTATTGGGGCGTACGGTGATCCCGTTGGAAACTCTGACCGGCCCTGATCTGGC
ATTGGTGGATTTGGGTACCTTGCCACTGGGCCGCTATCTGTTCAGCAGCGATGAACTGACTCGCGATTACATTCATATTG
GACGGCAAGATGCACTGTGGGCGCGCCGTTCCCGCCTGCGGCTGGCGGGTAAGCCGCTGTTGCTGACCGAACTGTTTTTA
CCGGCTTCGCCGCTGTACGCGACAGGAAGTTCGGTTCCCGAATGA

Upstream 100 bases:

>100_bases
GCCTGCCGCTTTTGAATTTCTGCGTTACAATGGGCGCCTGTTAACAGTTTGTCTGGTCTGGCGCGGCCGCAGGGTGCGGC
GTCAGGCATGGAGTAGAACA

Downstream 100 bases:

>100_bases
TGAGGAGAGAAAAAACCTTGGAAGGAAGCGTGAATCAAAGCAAATGGCAGGCTTATAGCCATCTGATGCGCATTAATAAA
CCCATTGGCACCTTGCTGTT

Product: chorismate pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSGNRDSILPPLEWLSAQHPPAPAAVSDWLMEPGSMTRRFERHCGRVHVEPQRECFVTRDQLGEEAEHLPDSPRYWLREV
VLLGDNQPWLLGRTVIPLETLTGPDLALVDLGTLPLGRYLFSSDELTRDYIHIGRQDALWARRSRLRLAGKPLLLTELFL
PASPLYATGSSVPE

Sequences:

>Translated_174_residues
MSGNRDSILPPLEWLSAQHPPAPAAVSDWLMEPGSMTRRFERHCGRVHVEPQRECFVTRDQLGEEAEHLPDSPRYWLREV
VLLGDNQPWLLGRTVIPLETLTGPDLALVDLGTLPLGRYLFSSDELTRDYIHIGRQDALWARRSRLRLAGKPLLLTELFL
PASPLYATGSSVPE
>Mature_173_residues
SGNRDSILPPLEWLSAQHPPAPAAVSDWLMEPGSMTRRFERHCGRVHVEPQRECFVTRDQLGEEAEHLPDSPRYWLREVV
LLGDNQPWLLGRTVIPLETLTGPDLALVDLGTLPLGRYLFSSDELTRDYIHIGRQDALWARRSRLRLAGKPLLLTELFLP
ASPLYATGSSVPE

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=139, Percent_Identity=61.8705035971223, Blast_Score=172, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_SERP5 (A8GKB8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480686.1
- ProteinModelPortal:   A8GKB8
- SMR:   A8GKB8
- STRING:   A8GKB8
- GeneID:   5607083
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4464
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   PLGELLY
- ProtClustDB:   PRK11655
- BioCyc:   SPRO399741:SPRO_4464-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19657; Mature: 19526

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: BINDING 36-36 BINDING 78-78 BINDING 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNRDSILPPLEWLSAQHPPAPAAVSDWLMEPGSMTRRFERHCGRVHVEPQRECFVTRD
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCEECCCCHHHHEECHH
QLGEEAEHLPDSPRYWLREVVLLGDNQPWLLGRTVIPLETLTGPDLALVDLGTLPLGRYL
HHCHHHHHCCCCHHHHHHHHHHCCCCCCEEECCEEECHHCCCCCCEEEEECCCCCHHHHH
FSSDELTRDYIHIGRQDALWARRSRLRLAGKPLLLTELFLPASPLYATGSSVPE
HCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure 
SGNRDSILPPLEWLSAQHPPAPAAVSDWLMEPGSMTRRFERHCGRVHVEPQRECFVTRD
CCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCEECCCCHHHHEECHH
QLGEEAEHLPDSPRYWLREVVLLGDNQPWLLGRTVIPLETLTGPDLALVDLGTLPLGRYL
HHCHHHHHCCCCHHHHHHHHHHCCCCCCEEECCEEECHHCCCCCCEEEEECCCCCHHHHH
FSSDELTRDYIHIGRQDALWARRSRLRLAGKPLLLTELFLPASPLYATGSSVPE
HCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA