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The map label for this gene is ubiA [H]

Identifier: 157372696

GI number: 157372696

Start: 4935729

End: 4936622

Strand: Reverse

Name: ubiA [H]

Synonym: Spro_4463

Alternate gene names: 157372696

Gene position: 4936622-4935729 (Counterclockwise)

Preceding gene: 157372697

Following gene: 157372694

Centisome position: 90.6

GC content: 55.7

Gene sequence:

>894_bases
ATGATGAGGAGAGAAAAAACCTTGGAAGGAAGCGTGAATCAAAGCAAATGGCAGGCTTATAGCCATCTGATGCGCATTAA
TAAACCCATTGGCACCTTGCTGTTGCTGTGGCCGACGCTGTGGGCACTGTGGCTGGCGGGCAAGGGCGTGCCGTCGCTGT
CTATCCTGGTGGTGTTCGTGGTTGGCGTCTTCCTGATGCGTGCCGCCGGTTGTGTCGTGAATGATTACGCCGATCGCGCT
GTCGATGGCCACGTGAAACGCACTGCCGCTCGTCCGATGCCGAGTGGCCGGGTGAGCGAGAAAGAGGCCAAGGTGCTGTT
TGTGGTGTTGGTGCTTGTCTCGTTCGGGCTGGTGCTGACGCTCAATGCGATGACCATCTGGCTGTCACTGGCGGCGCTGG
CGCTGGCGTGGGCCTATCCGTTTATGAAACGGGTCACTCACCTGCCGCAGTTTGTTCTTGGCGCGGCGTTTGGCTGGGGG
ATCCCGATGGCCTATGCCGCCGTCAGTGAATCCTTGCCACTGAGCTGCTGGCTGTTGCTGCTGGCCAATATTTGCTGGAC
GGTGGCTTACGACACCTTATATGCGATGGTTGACCGTGACGATGACCTGAAGATTGGCATTAAATCTACGGCTATTTTGT
TTGGTCGTTACGACAAGCTGATCGTCGGTTTGCTGCAGTTCGCCACGCTGCTGCTGATGCTGTGGGTAGGTTATCTGACG
CAGATGAGCGGGGCCTTTTACTGGTCGCTGTTGCTGGCCGGTGCCTTGTTTATCCATCAGCAAAAACAGATTGCCACCCG
TGAGCGTGACGCCTGCTTCAAGGCGTTCATGGATAACAATTATGTCGGGCTGGTGTTGTTTATCGGTATTGCTCTGAGTT
ACTGGCAGGGTTAA

Upstream 100 bases:

>100_bases
CGCGCCGTTCCCGCCTGCGGCTGGCGGGTAAGCCGCTGTTGCTGACCGAACTGTTTTTACCGGCTTCGCCGCTGTACGCG
ACAGGAAGTTCGGTTCCCGA

Downstream 100 bases:

>100_bases
GGCGTTACCGCAATAAAAAAGGCACCCTAGGGTGCCTTTTTGTTTTGTATCAATGGATTAGTCTTCTTTCTCTTCCGCTG
CGACCGTTTCCGGCAACGCG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MMRREKTLEGSVNQSKWQAYSHLMRINKPIGTLLLLWPTLWALWLAGKGVPSLSILVVFVVGVFLMRAAGCVVNDYADRA
VDGHVKRTAARPMPSGRVSEKEAKVLFVVLVLVSFGLVLTLNAMTIWLSLAALALAWAYPFMKRVTHLPQFVLGAAFGWG
IPMAYAAVSESLPLSCWLLLLANICWTVAYDTLYAMVDRDDDLKIGIKSTAILFGRYDKLIVGLLQFATLLLMLWVGYLT
QMSGAFYWSLLLAGALFIHQQKQIATRERDACFKAFMDNNYVGLVLFIGIALSYWQG

Sequences:

>Translated_297_residues
MMRREKTLEGSVNQSKWQAYSHLMRINKPIGTLLLLWPTLWALWLAGKGVPSLSILVVFVVGVFLMRAAGCVVNDYADRA
VDGHVKRTAARPMPSGRVSEKEAKVLFVVLVLVSFGLVLTLNAMTIWLSLAALALAWAYPFMKRVTHLPQFVLGAAFGWG
IPMAYAAVSESLPLSCWLLLLANICWTVAYDTLYAMVDRDDDLKIGIKSTAILFGRYDKLIVGLLQFATLLLMLWVGYLT
QMSGAFYWSLLLAGALFIHQQKQIATRERDACFKAFMDNNYVGLVLFIGIALSYWQG
>Mature_297_residues
MMRREKTLEGSVNQSKWQAYSHLMRINKPIGTLLLLWPTLWALWLAGKGVPSLSILVVFVVGVFLMRAAGCVVNDYADRA
VDGHVKRTAARPMPSGRVSEKEAKVLFVVLVLVSFGLVLTLNAMTIWLSLAALALAWAYPFMKRVTHLPQFVLGAAFGWG
IPMAYAAVSESLPLSCWLLLLANICWTVAYDTLYAMVDRDDDLKIGIKSTAILFGRYDKLIVGLLQFATLLLMLWVGYLT
QMSGAFYWSLLLAGALFIHQQKQIATRERDACFKAFMDNNYVGLVLFIGIALSYWQG

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=36.5591397849462, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1790473, Length=289, Percent_Identity=73.7024221453287, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17553718, Length=279, Percent_Identity=35.84229390681, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=35.84229390681, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17553720, Length=181, Percent_Identity=40.8839779005525, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=43.1654676258993, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=42.7536231884058, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=307, Percent_Identity=32.8990228013029, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355567, Length=294, Percent_Identity=37.4149659863946, Blast_Score=201, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33151; Mature: 33151

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRREKTLEGSVNQSKWQAYSHLMRINKPIGTLLLLWPTLWALWLAGKGVPSLSILVVFV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VGVFLMRAAGCVVNDYADRAVDGHVKRTAARPMPSGRVSEKEAKVLFVVLVLVSFGLVLT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LNAMTIWLSLAALALAWAYPFMKRVTHLPQFVLGAAFGWGIPMAYAAVSESLPLSCWLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LANICWTVAYDTLYAMVDRDDDLKIGIKSTAILFGRYDKLIVGLLQFATLLLMLWVGYLT
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSGAFYWSLLLAGALFIHQQKQIATRERDACFKAFMDNNYVGLVLFIGIALSYWQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRREKTLEGSVNQSKWQAYSHLMRINKPIGTLLLLWPTLWALWLAGKGVPSLSILVVFV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VGVFLMRAAGCVVNDYADRAVDGHVKRTAARPMPSGRVSEKEAKVLFVVLVLVSFGLVLT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LNAMTIWLSLAALALAWAYPFMKRVTHLPQFVLGAAFGWGIPMAYAAVSESLPLSCWLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LANICWTVAYDTLYAMVDRDDDLKIGIKSTAILFGRYDKLIVGLLQFATLLLMLWVGYLT
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSGAFYWSLLLAGALFIHQQKQIATRERDACFKAFMDNNYVGLVLFIGIALSYWQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA