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The map label for this gene is csrD [H]

Identifier: 157372645

GI number: 157372645

Start: 4885291

End: 4887222

Strand: Reverse

Name: csrD [H]

Synonym: Spro_4412

Alternate gene names: 157372645

Gene position: 4887222-4885291 (Counterclockwise)

Preceding gene: 157372660

Following gene: 157372644

Centisome position: 89.69

GC content: 56.21

Gene sequence:

>1932_bases
ATGCGATTTACCACCAAGCTCTCTGCATTGATCACCCTGCTTGTTGCTCTGGCGATGTTTTTGATGCTGATGGGCTGCTC
ATACAGTTACTTTTACGTCACTCAGGAGAGGCTGGATCGCCGCTTCAATTCGCTGATGACCTCGCTCGATCAGGCCATGC
TGCGTGAATCTCCACAGGAACAGGAACAATGGTTACCGCTGGTGATGCGTCCGCTTGGTATCGTGGCCGTCAGCGTGGAT
ACCAGCCACAGCAATCTTCTTTCTTATCATCTGCCAACGGTAAAGCAGCCCTGGGAATCGCTCAACGGCTACCGGCAGGT
TTCCCTGCCGTTGATGCAGCATCCCGGCGCTTCGCTACGCATTACCTATATTGACCCTTTCGCCAGCGACGTGCGTTCGT
TGCAATCCACTGCGGCTGTCACTTTGTCGATCGTCGTGATGGTGGTTATCTTGCTGCTCAGTTTGCGTTGGTTACGCGAT
CAGGCCGACGGGGAGGACCGGCTGGAACGCCGTGCACGCCGTATTCTTAATGGCGAACGAGAGAGCGTGATGCAGGGCGA
CGTGCGCGAATGGCCGGCAAACGTCAGCGGAGCACTCGATCGCCTGCTGGCGGATCTGGCGGAAGCGCGCGAGGAGCGTA
GCCGGGTCGATACGCTGATCCGCGCCTTTGCCGCTCAGGACGCCAAAACCGGGCTGAACAACCGATTGTTCTTTGATAAC
CAACTGACCACGCAGTTGGAGGAGGAAGGTTCGCACGGCATTGTCATGATGGTGCGATTACCGGATTTCGACACGCTGCG
GGAAACCCACGGCAACAGTGCGGTGCAAGAACTGATGTATTCGCTGGTCAATCTGTTGTCGACCTTCGTGATGCGCTACC
CGGCGGCGTTGCTGGCGCGCTATTTCCACAGCGATTTCACCGTTTTGTTGCCGCATCGCACGCTGAAAGAGGCGGACGGC
ATTGCTTCACAGTTGGTTCATGCCATTGACGCCTTGCCTTCGACGGCGCTTATCGATCGCGAGGCGTTTTTGCATATCGG
TATTGTGGCCTACCGCAGTGGACAAAGTACCGAACAGGTGATTGATCATGCAGAGCAGGCCACGCGCCACGCGACGCTGC
AGGGGGAAAACGGCTGGTATGTCTACGACAGCCAGGTGCCGGAAAAAGGGCGCGGCAGCGTCAAATGGCGCACTCTGTTG
GAACAGGTTCTGGCACGGGGCGGGCCACGGTTGTACCAGAAACCGGCAGTGACGGTGGAGGGGGAAGTTCATCACCGGGA
GATCATGAGCCGGATATACGATGGGACCCAGGAACTGCTGCCATCTGAATATATGCCGTTGGTGCAGCAGTTGGGGCTGG
CGGAGAGTTACGACCGCCAGCATTTGAGTCGCATTCTTCCTTTACTGGCGCTGTGGCCTGAAGAAACGCTGGCATTTACG
CTGTCCGTAGATTCATTATTGCAACGCACTTTCCAGCGTTGGCTGCGTGATAGCCTGTTACAGTGTGAAAAAAGTCATCG
TCGGCGAATTCTGATTGAACTTGCAGAGGCAGACGTGTGTCAACATATCGACCGTTTACGCCCGGTGTTGAGATTACTCT
CTGGATTGGGGTGTCGTCTGGCCGTGTCCCAGGCGGGGTTAACCGTAGTTAGTACCTCCTATATCAAGTCCTTACCGGTG
GAACTGGTCAAGCTCCACCCTGGTTTGGTGCGGAGTATTGATAAGCGGGATGAGAATCAGCTGTTCGTTCAGAGCCTGAC
GGGTGCCTGCGAAGGGACCAGTACCCAGGTTTTTGCCGCCAGCGTGCGGACGCGTAATGAATGGCAGACGCTGAAAGATC
GCGGGATCCTCGGCGGGCAGGGTGACTTTTTCGCGTCGCCGGAACCGATAGACGCAGGGCGTAAAAAATATTCGCGTCGT
TATCGCGTTTAA

Upstream 100 bases:

>100_bases
TAAAAATCAGGGTATTGTGTTGGATTCTTTTGAGCGGATTCGGGGCCTTTATACGACCAAAGGTGATAATTCACGTAACC
ATAACGGACAAGGCACAGGG

Downstream 100 bases:

>100_bases
CCTGAATGCCGGGCAAAAATTGACGTAGAATGAGCGCCAATTCATCTGGGCTATTTTATCTGTCTTTTTGGGGTTATCCC
CAAACTGCCTGCGACAATGA

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MRFTTKLSALITLLVALAMFLMLMGCSYSYFYVTQERLDRRFNSLMTSLDQAMLRESPQEQEQWLPLVMRPLGIVAVSVD
TSHSNLLSYHLPTVKQPWESLNGYRQVSLPLMQHPGASLRITYIDPFASDVRSLQSTAAVTLSIVVMVVILLLSLRWLRD
QADGEDRLERRARRILNGERESVMQGDVREWPANVSGALDRLLADLAEAREERSRVDTLIRAFAAQDAKTGLNNRLFFDN
QLTTQLEEEGSHGIVMMVRLPDFDTLRETHGNSAVQELMYSLVNLLSTFVMRYPAALLARYFHSDFTVLLPHRTLKEADG
IASQLVHAIDALPSTALIDREAFLHIGIVAYRSGQSTEQVIDHAEQATRHATLQGENGWYVYDSQVPEKGRGSVKWRTLL
EQVLARGGPRLYQKPAVTVEGEVHHREIMSRIYDGTQELLPSEYMPLVQQLGLAESYDRQHLSRILPLLALWPEETLAFT
LSVDSLLQRTFQRWLRDSLLQCEKSHRRRILIELAEADVCQHIDRLRPVLRLLSGLGCRLAVSQAGLTVVSTSYIKSLPV
ELVKLHPGLVRSIDKRDENQLFVQSLTGACEGTSTQVFAASVRTRNEWQTLKDRGILGGQGDFFASPEPIDAGRKKYSRR
YRV

Sequences:

>Translated_643_residues
MRFTTKLSALITLLVALAMFLMLMGCSYSYFYVTQERLDRRFNSLMTSLDQAMLRESPQEQEQWLPLVMRPLGIVAVSVD
TSHSNLLSYHLPTVKQPWESLNGYRQVSLPLMQHPGASLRITYIDPFASDVRSLQSTAAVTLSIVVMVVILLLSLRWLRD
QADGEDRLERRARRILNGERESVMQGDVREWPANVSGALDRLLADLAEAREERSRVDTLIRAFAAQDAKTGLNNRLFFDN
QLTTQLEEEGSHGIVMMVRLPDFDTLRETHGNSAVQELMYSLVNLLSTFVMRYPAALLARYFHSDFTVLLPHRTLKEADG
IASQLVHAIDALPSTALIDREAFLHIGIVAYRSGQSTEQVIDHAEQATRHATLQGENGWYVYDSQVPEKGRGSVKWRTLL
EQVLARGGPRLYQKPAVTVEGEVHHREIMSRIYDGTQELLPSEYMPLVQQLGLAESYDRQHLSRILPLLALWPEETLAFT
LSVDSLLQRTFQRWLRDSLLQCEKSHRRRILIELAEADVCQHIDRLRPVLRLLSGLGCRLAVSQAGLTVVSTSYIKSLPV
ELVKLHPGLVRSIDKRDENQLFVQSLTGACEGTSTQVFAASVRTRNEWQTLKDRGILGGQGDFFASPEPIDAGRKKYSRR
YRV
>Mature_643_residues
MRFTTKLSALITLLVALAMFLMLMGCSYSYFYVTQERLDRRFNSLMTSLDQAMLRESPQEQEQWLPLVMRPLGIVAVSVD
TSHSNLLSYHLPTVKQPWESLNGYRQVSLPLMQHPGASLRITYIDPFASDVRSLQSTAAVTLSIVVMVVILLLSLRWLRD
QADGEDRLERRARRILNGERESVMQGDVREWPANVSGALDRLLADLAEAREERSRVDTLIRAFAAQDAKTGLNNRLFFDN
QLTTQLEEEGSHGIVMMVRLPDFDTLRETHGNSAVQELMYSLVNLLSTFVMRYPAALLARYFHSDFTVLLPHRTLKEADG
IASQLVHAIDALPSTALIDREAFLHIGIVAYRSGQSTEQVIDHAEQATRHATLQGENGWYVYDSQVPEKGRGSVKWRTLL
EQVLARGGPRLYQKPAVTVEGEVHHREIMSRIYDGTQELLPSEYMPLVQQLGLAESYDRQHLSRILPLLALWPEETLAFT
LSVDSLLQRTFQRWLRDSLLQCEKSHRRRILIELAEADVCQHIDRLRPVLRLLSGLGCRLAVSQAGLTVVSTSYIKSLPV
ELVKLHPGLVRSIDKRDENQLFVQSLTGACEGTSTQVFAASVRTRNEWQTLKDRGILGGQGDFFASPEPIDAGRKKYSRR
YRV

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=648, Percent_Identity=57.2530864197531, Blast_Score=762, Evalue=0.0,
Organism=Escherichia coli, GI1787541, Length=442, Percent_Identity=22.3981900452489, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=21.4611872146119, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=24.7899159663866, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=23.728813559322, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 72892; Mature: 72892

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTTKLSALITLLVALAMFLMLMGCSYSYFYVTQERLDRRFNSLMTSLDQAMLRESPQE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCH
QEQWLPLVMRPLGIVAVSVDTSHSNLLSYHLPTVKQPWESLNGYRQVSLPLMQHPGASLR
HHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCHHHCCCCEEECCHHHHCCCCEEE
ITYIDPFASDVRSLQSTAAVTLSIVVMVVILLLSLRWLRDQADGEDRLERRARRILNGER
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCH
ESVMQGDVREWPANVSGALDRLLADLAEAREERSRVDTLIRAFAAQDAKTGLNNRLFFDN
HHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
QLTTQLEEEGSHGIVMMVRLPDFDTLRETHGNSAVQELMYSLVNLLSTFVMRYPAALLAR
HHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFHSDFTVLLPHRTLKEADGIASQLVHAIDALPSTALIDREAFLHIGIVAYRSGQSTEQV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEHEEECCCCCHHHH
IDHAEQATRHATLQGENGWYVYDSQVPEKGRGSVKWRTLLEQVLARGGPRLYQKPAVTVE
HHHHHHHHHHCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GEVHHREIMSRIYDGTQELLPSEYMPLVQQLGLAESYDRQHLSRILPLLALWPEETLAFT
CCHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHEEEE
LSVDSLLQRTFQRWLRDSLLQCEKSHRRRILIELAEADVCQHIDRLRPVLRLLSGLGCRL
ECHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
AVSQAGLTVVSTSYIKSLPVELVKLHPGLVRSIDKRDENQLFVQSLTGACEGTSTQVFAA
EHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
SVRTRNEWQTLKDRGILGGQGDFFASPEPIDAGRKKYSRRYRV
HHHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRFTTKLSALITLLVALAMFLMLMGCSYSYFYVTQERLDRRFNSLMTSLDQAMLRESPQE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCH
QEQWLPLVMRPLGIVAVSVDTSHSNLLSYHLPTVKQPWESLNGYRQVSLPLMQHPGASLR
HHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCHHHCCCCEEECCHHHHCCCCEEE
ITYIDPFASDVRSLQSTAAVTLSIVVMVVILLLSLRWLRDQADGEDRLERRARRILNGER
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCH
ESVMQGDVREWPANVSGALDRLLADLAEAREERSRVDTLIRAFAAQDAKTGLNNRLFFDN
HHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
QLTTQLEEEGSHGIVMMVRLPDFDTLRETHGNSAVQELMYSLVNLLSTFVMRYPAALLAR
HHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFHSDFTVLLPHRTLKEADGIASQLVHAIDALPSTALIDREAFLHIGIVAYRSGQSTEQV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEHEEECCCCCHHHH
IDHAEQATRHATLQGENGWYVYDSQVPEKGRGSVKWRTLLEQVLARGGPRLYQKPAVTVE
HHHHHHHHHHCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GEVHHREIMSRIYDGTQELLPSEYMPLVQQLGLAESYDRQHLSRILPLLALWPEETLAFT
CCHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHEEEE
LSVDSLLQRTFQRWLRDSLLQCEKSHRRRILIELAEADVCQHIDRLRPVLRLLSGLGCRL
ECHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
AVSQAGLTVVSTSYIKSLPVELVKLHPGLVRSIDKRDENQLFVQSLTGACEGTSTQVFAA
EHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
SVRTRNEWQTLKDRGILGGQGDFFASPEPIDAGRKKYSRRYRV
HHHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]