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The map label for this gene is sstT

Identifier: 157372552

GI number: 157372552

Start: 4788702

End: 4789937

Strand: Direct

Name: sstT

Synonym: Spro_4319

Alternate gene names: 157372552

Gene position: 4788702-4789937 (Clockwise)

Preceding gene: 157372551

Following gene: 157372555

Centisome position: 87.88

GC content: 58.82

Gene sequence:

>1236_bases
ATGCAAAAACTATTACAGAAGATCACTCAGGGCAGTCTGGTCAAACAAATCATGGTCGGCCTGGTGGCCGGTATTATCGT
GGCGTTGGTCTCACCGGCAACGGCTTCGGCTGTGGGCTTGCTGGGTGCGCTGTTCGTTGGCGCACTGAAAGCGGTGGCGC
CGGTACTGGTGCTGGTGTTGGTCATGGCCTCAATCGCCAATCACAAACACGGGCAGAAAACCAATATCCGGCCGATCCTG
TTCCTTTACCTGCTGGGCACTTTCGCTGCGGCGCTGGTGGCGGTCGTGGTCAGCTTTATGTTCCCGTCCAACCTGGCGCT
GGTAGCCGGCAATGCCGAGATCAACCCACCGGGCGGCATTATTGAGGTGCTGAAAGGCCTGCTGTTGAGCGTGGTGGCCA
ACCCGTTCCAGGCGCTGATTAGCGCTAACTATATTGGTATTCTGGCCTGGGCAGTGGGGCTGGGACTGGCGCTGCGTCAC
TCCTCTGACACCACCAAATCATTGATTAACGATATGTCACATGCAGTCACCATGGTGGTGCGTGCGGTGATCCGCTGTGC
CCCGCTTGGCATCTTCGGCCTGGTGGCTTCGACGCTGGCCGAAACCGGCTTCGGCGCGCTGTGGGGTTATGCTCAACTGC
TGGTGGTACTGATCGGCTGTATGTTGCTGGTCGCACTGGTGCTGAACCCGCTGATCGTTTTCTGGAAAATCCGTCGCAAT
CCTTATCCGCTGGTGTTCGCCTGCCTGCGTGAAAGCGGCGTGACCGCATTCTTCACCCGCAGTTCGGCCGCCAATATTCC
GGTGAATATGGAGCTGTGCAAAAAACTGAATCTGAACGAAGACACCTATTCGGTTTCTATCCCGCTGGGTGCGACCATCA
ATATGGCCGGTGCGGCGATCACCATTACCGTGCTGACGCTGGCGGCGGTGCATACTCTGGGGATCCCGGTTGACGTGCCG
ACCGCGCTGCTGCTGAGCGTAGTGGCCGCCGTCTGCGCCTGCGGCGCTTCCGGTGTGGCCGGCGGTTCGCTGTTGCTGAT
CCCGTTGGCGTGTAACATGTTCGGCATCCCGAACGACGTGGCCATGCAGGTGGTCGCCGTCGGCTTTATCATCGGCGTGC
TGCAAGACTCCGCCGAAACCGCACTGAACTCTTCTACCGACGTCCTGTTTACTGCCGCAGCCTGTCAGGCGGAAGACCAA
CGTTTGGCAGATGAAGATCCGCTGAAGGTGCGTTAA

Upstream 100 bases:

>100_bases
ATTTGGCAAACACACTTGGTTACAGATTCAAATAAAGTTGTCCGGCGAGGTTCCCGCCGAGATAAAGCTGTAAGCAACAT
CATCGGGAAGAAAAAGCACT

Downstream 100 bases:

>100_bases
TTTCCGAGCTTATTCAACAAGGCGCTCATTATCGGGCGCCTTTTTTTACCTCAATATCACAGTCCTACAAGGTTACCCCG
CTTTTAAAAATCGCCAACTC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVLVMASIANHKHGQKTNIRPIL
FLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGIIEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRH
SSDTTKSLINDMSHAVTMVVRAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRN
PYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDVP
TALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQ
RLADEDPLKVR

Sequences:

>Translated_411_residues
MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVLVMASIANHKHGQKTNIRPIL
FLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGIIEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRH
SSDTTKSLINDMSHAVTMVVRAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRN
PYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDVP
TALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQ
RLADEDPLKVR
>Mature_411_residues
MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVLVMASIANHKHGQKTNIRPIL
FLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGIIEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRH
SSDTTKSLINDMSHAVTMVVRAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRN
PYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDVP
TALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQ
RLADEDPLKVR

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI4827012, Length=241, Percent_Identity=26.1410788381743, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI223468566, Length=261, Percent_Identity=28.3524904214559, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223468564, Length=255, Percent_Identity=28.6274509803922, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI5032093, Length=304, Percent_Identity=27.9605263157895, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI21314632, Length=278, Percent_Identity=27.3381294964029, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI169790839, Length=270, Percent_Identity=22.5925925925926, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI66773030, Length=272, Percent_Identity=24.2647058823529, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789473, Length=402, Percent_Identity=78.3582089552239, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI1789947, Length=359, Percent_Identity=23.9554317548747, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790514, Length=417, Percent_Identity=24.220623501199, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537407, Length=435, Percent_Identity=23.9080459770115, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193206505, Length=270, Percent_Identity=27.4074074074074, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71996953, Length=268, Percent_Identity=25.7462686567164, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983099, Length=278, Percent_Identity=25.8992805755396, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71983106, Length=278, Percent_Identity=25.8992805755396, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583025, Length=277, Percent_Identity=26.3537906137184, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137668, Length=277, Percent_Identity=26.3537906137184, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583023, Length=277, Percent_Identity=26.3537906137184, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_SERP5 (A8GJX3)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480541.1
- ProteinModelPortal:   A8GJX3
- STRING:   A8GJX3
- GeneID:   5606618
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4319
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   THIRPIL
- ProtClustDB:   PRK13628
- BioCyc:   SPRO399741:SPRO_4319-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 42594; Mature: 42594

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1146eb98)-; HASH(0x118f0a04)-; HASH(0x112b0f38)-; HASH(0x118f074c)-; HASH(0x11aeadfc)-; HASH(0x112b8c8c)-; HASH(0x1167eaf4)-; HASH(0x10518b34)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMASIANHKHGQKTNIRPILFLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
IEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRHSSDTTKSLINDMSHAVTMVV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
RAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRN
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAI
CCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCEEECCCHHH
TITVLTLAAVHTLGIPVDVPTALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCCHHH
AMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQRLADEDPLKVR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHCCCCCCCCCH
>Mature Secondary Structure
MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMASIANHKHGQKTNIRPILFLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
IEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRHSSDTTKSLINDMSHAVTMVV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
RAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRN
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAI
CCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCEEECCCHHH
TITVLTLAAVHTLGIPVDVPTALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCCHHH
AMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQRLADEDPLKVR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA