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The map label for this gene is yicJ [H]

Identifier: 157372248

GI number: 157372248

Start: 4454446

End: 4455846

Strand: Direct

Name: yicJ [H]

Synonym: Spro_4014

Alternate gene names: 157372248

Gene position: 4454446-4455846 (Clockwise)

Preceding gene: 157372247

Following gene: 157372249

Centisome position: 81.75

GC content: 54.82

Gene sequence:

>1401_bases
ATGAAGAGCAACGCCCTATCAATAAAAGAAAAGATTGGCTACGGCATGGGAGATGCCGGCTGCAACATGATCGGCGGAGC
GATTATGCTGTTTCTCAACTATTTCTATACCGATATCTACGGTCTGACTCCCGCACTGGTCGGCGTGCTGCTGCTGTCAG
TCCGCGTGCTGGATGCCATCACCGATCCGATCATGGGCGCAATAGCCGATCGCACCCAAAGCCGTTGGGGTCGCTTCCGC
CCCTGGTTGCTGTGGATCTCCCTGCCATATGTATTATTCAGCGTGTTGATGTTTACGACGCCGGAATGGAGCTACAACAG
CAAAGTGGTCTACGCCTTCGCCACTTACTTCTTGATGTCGCTGACCTACACGGCGATCAATATCCCCTACTGTTCGCTGG
GCGGCGTGATCACCGCCGATCCGCACGAACGGGTCTCCTGTCAGTCCTACCGTTTTATCCTGGTCGGTATCGCTACCCTG
ATCCTGTCCCTGACGCTGCTGCCAATGGCTGAATGGTTTGGCGGCGCAAACAAGGCGCGTGGCTATCAGATGGCAATGGG
TGTACTGGCACTGATTGCCCTGTTCATGTTTCTGTTCTGCTTTGCCACGGTCAAAGAACGTATACGTCCGGCAGTGCCAA
CCCATGACGCCCTTAAATCCGATCTGAGAGACGTGTGGAAAAACGATCAGTGGGTGCGCATTCTGCTGCTGACGTTTTGC
AACGTCTGCCCCGGTTTTATCCGCATGGCCGCCACCATGTATTACGTCACCTACGTCATGCAACAATCAACCTCCTTTGC
CAGTCTGTTTATCGCGCTGGGCGTCGTTGGCATGATGGTTGGCAGCGCATTGGCCAAGCCCCTGACCGATCGCTTCTGCA
AACTGAAAGTGTTCTTCTGGACCAATATTTTGCTGGCGGCGTTTTCGTGCGGCTTCTATTTCCTCAACCCTCAGTTCACT
TCGCTGATCGTCGCCGCCTATTTCCTGCTGAATATCCTGCATCAGATCCCTTCGCCGCTGCACTGGTCGTTAATGGCCGA
CGTGGACGATTACGGCGAATGGAAAACCGGCAAGCGCATCACCGGCATCAGTTTTTCCGGCAATCTGTTCTTCCTTAAGG
TCGGGCTGGCGGTGGCCGGCGCCATGGTGGGCTTCCTGATGTCGCTGTCCGGCTATCAGGCCGATGCGGTCAGCCAAAGC
GCTGGCGCACTTAACAGCATCGTGCTGTTGTTCACCGTGATCCCCGGTATCGGATATCTGATCACTGCCGGCGTGGTACG
CCTGCTGAAGGTTGATCGCCAACTGATGCGTCAGATTCAGATCGACCTGGAAAAGCGACGCATTAATTACCGCGAGCTAA
CCGACTACTCTGAGCAGCAACTAAAAACCCGAACCCCGTAA

Upstream 100 bases:

>100_bases
TTGTCCATCTCTACAACCATTCACTTCTGATAACTCGCCGCCAACCGGGACAATAATCGTTGCCACTCAGTTAGACTTTG
CCGGCGCGGAGAAAATGTCC

Downstream 100 bases:

>100_bases
GGAGCCTGCGATGCGCGACTACCCTAATCCCTTGATTGAACAGCGGGCCGATCCCTTTGTTTTGCGCCACAGCGATGGCT
ATTACTACTTCACCGCCTCG

Product: sugar (glycoside-Pentoside-hexuronide) transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKSNALSIKEKIGYGMGDAGCNMIGGAIMLFLNYFYTDIYGLTPALVGVLLLSVRVLDAITDPIMGAIADRTQSRWGRFR
PWLLWISLPYVLFSVLMFTTPEWSYNSKVVYAFATYFLMSLTYTAINIPYCSLGGVITADPHERVSCQSYRFILVGIATL
ILSLTLLPMAEWFGGANKARGYQMAMGVLALIALFMFLFCFATVKERIRPAVPTHDALKSDLRDVWKNDQWVRILLLTFC
NVCPGFIRMAATMYYVTYVMQQSTSFASLFIALGVVGMMVGSALAKPLTDRFCKLKVFFWTNILLAAFSCGFYFLNPQFT
SLIVAAYFLLNILHQIPSPLHWSLMADVDDYGEWKTGKRITGISFSGNLFFLKVGLAVAGAMVGFLMSLSGYQADAVSQS
AGALNSIVLLFTVIPGIGYLITAGVVRLLKVDRQLMRQIQIDLEKRRINYRELTDYSEQQLKTRTP

Sequences:

>Translated_466_residues
MKSNALSIKEKIGYGMGDAGCNMIGGAIMLFLNYFYTDIYGLTPALVGVLLLSVRVLDAITDPIMGAIADRTQSRWGRFR
PWLLWISLPYVLFSVLMFTTPEWSYNSKVVYAFATYFLMSLTYTAINIPYCSLGGVITADPHERVSCQSYRFILVGIATL
ILSLTLLPMAEWFGGANKARGYQMAMGVLALIALFMFLFCFATVKERIRPAVPTHDALKSDLRDVWKNDQWVRILLLTFC
NVCPGFIRMAATMYYVTYVMQQSTSFASLFIALGVVGMMVGSALAKPLTDRFCKLKVFFWTNILLAAFSCGFYFLNPQFT
SLIVAAYFLLNILHQIPSPLHWSLMADVDDYGEWKTGKRITGISFSGNLFFLKVGLAVAGAMVGFLMSLSGYQADAVSQS
AGALNSIVLLFTVIPGIGYLITAGVVRLLKVDRQLMRQIQIDLEKRRINYRELTDYSEQQLKTRTP
>Mature_466_residues
MKSNALSIKEKIGYGMGDAGCNMIGGAIMLFLNYFYTDIYGLTPALVGVLLLSVRVLDAITDPIMGAIADRTQSRWGRFR
PWLLWISLPYVLFSVLMFTTPEWSYNSKVVYAFATYFLMSLTYTAINIPYCSLGGVITADPHERVSCQSYRFILVGIATL
ILSLTLLPMAEWFGGANKARGYQMAMGVLALIALFMFLFCFATVKERIRPAVPTHDALKSDLRDVWKNDQWVRILLLTFC
NVCPGFIRMAATMYYVTYVMQQSTSFASLFIALGVVGMMVGSALAKPLTDRFCKLKVFFWTNILLAAFSCGFYFLNPQFT
SLIVAAYFLLNILHQIPSPLHWSLMADVDDYGEWKTGKRITGISFSGNLFFLKVGLAVAGAMVGFLMSLSGYQADAVSQS
AGALNSIVLLFTVIPGIGYLITAGVVRLLKVDRQLMRQIQIDLEKRRINYRELTDYSEQQLKTRTP

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=490, Percent_Identity=24.8979591836735, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI42713696, Length=495, Percent_Identity=23.030303030303, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI211063479, Length=508, Percent_Identity=22.4409448818898, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082306, Length=466, Percent_Identity=43.9914163090129, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1786466, Length=447, Percent_Identity=37.5838926174497, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1787902, Length=455, Percent_Identity=28.3516483516484, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1790561, Length=462, Percent_Identity=29.6536796536797, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI48994989, Length=457, Percent_Identity=28.0087527352298, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI145693206, Length=453, Percent_Identity=26.2693156732892, Blast_Score=149, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52136; Mature: 52136

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]