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The map label for this gene is fhuA [H]

Identifier: 157372213

GI number: 157372213

Start: 4410208

End: 4412397

Strand: Reverse

Name: fhuA [H]

Synonym: Spro_3979

Alternate gene names: 157372213

Gene position: 4412397-4410208 (Counterclockwise)

Preceding gene: 157372214

Following gene: 157372212

Centisome position: 80.98

GC content: 54.84

Gene sequence:

>2190_bases
ATGTCGACCAAGCGTCTTTCATCTTCCGGGGCCAAGCAGGGCCGCACTCATGTCAGTGGGTTAGCGATAACTATCGCTGC
CGCACTTGGTACGCTGGCGATGCCGGCATTTTCCGCCGACACCAAGGAAGAGACCCTTACCGTGGTGGGCAGCAGCCAAC
CGCAGCAGGAAAGCGCCTGGGGGCCGGTCGGCACCTATGTGGCCAAGCACAGCGCCACCGGTACCAAAACCGATACGCCG
ATCGAAAAGACCCCGCAGTCGATTTCCGTGGTAACGCGTGAAGAGATGGATATGCGCCAGCCGGAGACGGTGAAAGGTGC
GCTGGCTTATTCGCCGGGGGTGATGGTGGGCAACCGTGGTGCCTCCACCGCCTACGATGCCGTGAACATTCGTGGCTTCA
GTTCGGTAGGTACCAATATGTACCTCGACGGCCTGAAACTGCAGGACGACAACTACTCCATTTACCAGATCGATCCTTAC
TTCCTTGAGCGTGCCGAAGTGCTGCGTGGTCCTTCTTCGGTACTCTATGGCAAGAGCAATCCGGGTGGAGTCGTCGCTCT
GGTCAGCAAACGCCCGACCACCGAAAGCCTGCGTGAAGTTCAGTTCAAGATGGGTACCGACAACCTGTTCCAGACCGGTT
TCGATTTTGGCGGCGCAGTGGATGATGATGGTGTTTACTCTTACCGTTTGACAGGTCTGGCGCGTGATGAAGATCAGCAG
CAGGTGGGCGAAAAGAGTAAGCGCTATGCTATCGCGCCTTCTTTCAGTTGGCGGCCGGATGATCGTACTTCTTTGACTTT
CCTCAGCAGTTTCCAGGATGATCCTGACCTGGGCTTCTATGGCTGGCTGCCGAAAGAGGGCACGGTGCAAAATGGCATCA
ACGGCAAGTTGCCAACCAGTTTCAACGACGGTGAGCCGGGTTATAACAACATCTCGCGCAAGCAACAGATGGTCGGTTAT
GCCTTCGAGCACGGTTTTGACGACGTGTGGACGGTGCGCCAAAACCTGCGTTACTCAAAAATGGATCTTGATTACCGTTC
CATTTATGGTCAGGGCATCAGTCCGACTAACCCGGCAGAACTGACGCGTGGCGTGATGAACTCGAAAGAGCATTTGTCGA
GCTTTGCGGTGGACACCCAGGCCCAGGCAAAATTTGCCACCGGCGTGGTTGATCATACCTTGCTGATGGGGGTGGACTAC
ATGCGCATGCGCAATGACGTCGTCTATCAGTACGGCACCGCTTCCCCGCTGAATGTCGTAGCTCCACAGTACGGCAACCA
AAATTACACCATTACCGGTGGTGCAAGTCAGGTCAATCGTCAGGAGCAAACCGGGCTTTACGTACAGGATCAGGCCGAGT
GGAATCAATGGGTGCTGACCATGGGAGGGCGCTATGACTGGAGCGATACCAACAGCACCAACCGTTTGAATCAGAACTCG
GTATCCAAGCAAAAAGACAACGAATTCACCGGCCGGGCTGGCTTGAATTATGTCTTTGAAAACGGTATTGCGCCGTATGT
CAGCTACAGTGAATCCTTTGAGCCGACTTCCGGCACGGACTTCAGTGGTAACACCTTCGCCGCCTCCAAGGGCAAGCAGT
ATGAAGCCGGTGTGAAGTTTGCGCCGAAAGATCGTCCTATTACTGCCAGCATGGCGATCTATCAGCTGACCAAGACCAAC
AACAAGGTGGCTGACCCTAATCCAGATCATCCATTCGCCAGCGTGCAGGGCGGCGAGATCCGTTCCCGCGGGGTCGAACT
GGAAGCCAAAGCCGCGCTGTCGGCCAACCTTAATCTGCTGGGTTCTTATACCTACACGGATGCCGAGTATTCCAAAGACA
CTACGCTGCAGGGCAATACCCCTGCCGCGATCCCAAAACATATGGCTTCACTGTGGGCGGATTACACCTTCCATGAAACC
GCCATCAGTGGCCTGACCCTGGGGTCTGGTGTTCGCTATGTCGGCTCCAGCTATGGTGATGAAGCCAATACCTTTAAAGT
GAAAGACTACACGGTGGTTGATGCTGCGATAAAATACGATCTGGCGCGTTTCAATCTGCCGGGTTCCTCGATTGGCATCA
ATGTGAATAACCTGTTTGATAAAGAATACGTCTCTAGCTGCTTTGCCACCTACGGCTGCTATTGGGGCGCAGAACGCCAG
GTGGTCGCCACCGCAACCTTCCGCTTCTAA

Upstream 100 bases:

>100_bases
TGAGCTTGCAGTTTAATTTGGCTTCTGCATAAAATGCGGCGCTTATAATAATTATTATCGTTTACATTCGTCATCAAATA
ATTTACCAGAGAAACCATCT

Downstream 100 bases:

>100_bases
CCGGATCACCGGGGCGGCATCATGTCGCCCCGGAAAAAGTAGGACCTATGCAGGATAAACACCCCAATCACGACGCCACT
TTTACGTTAGACAGCGCCAG

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MSTKRLSSSGAKQGRTHVSGLAITIAAALGTLAMPAFSADTKEETLTVVGSSQPQQESAWGPVGTYVAKHSATGTKTDTP
IEKTPQSISVVTREEMDMRQPETVKGALAYSPGVMVGNRGASTAYDAVNIRGFSSVGTNMYLDGLKLQDDNYSIYQIDPY
FLERAEVLRGPSSVLYGKSNPGGVVALVSKRPTTESLREVQFKMGTDNLFQTGFDFGGAVDDDGVYSYRLTGLARDEDQQ
QVGEKSKRYAIAPSFSWRPDDRTSLTFLSSFQDDPDLGFYGWLPKEGTVQNGINGKLPTSFNDGEPGYNNISRKQQMVGY
AFEHGFDDVWTVRQNLRYSKMDLDYRSIYGQGISPTNPAELTRGVMNSKEHLSSFAVDTQAQAKFATGVVDHTLLMGVDY
MRMRNDVVYQYGTASPLNVVAPQYGNQNYTITGGASQVNRQEQTGLYVQDQAEWNQWVLTMGGRYDWSDTNSTNRLNQNS
VSKQKDNEFTGRAGLNYVFENGIAPYVSYSESFEPTSGTDFSGNTFAASKGKQYEAGVKFAPKDRPITASMAIYQLTKTN
NKVADPNPDHPFASVQGGEIRSRGVELEAKAALSANLNLLGSYTYTDAEYSKDTTLQGNTPAAIPKHMASLWADYTFHET
AISGLTLGSGVRYVGSSYGDEANTFKVKDYTVVDAAIKYDLARFNLPGSSIGINVNNLFDKEYVSSCFATYGCYWGAERQ
VVATATFRF

Sequences:

>Translated_729_residues
MSTKRLSSSGAKQGRTHVSGLAITIAAALGTLAMPAFSADTKEETLTVVGSSQPQQESAWGPVGTYVAKHSATGTKTDTP
IEKTPQSISVVTREEMDMRQPETVKGALAYSPGVMVGNRGASTAYDAVNIRGFSSVGTNMYLDGLKLQDDNYSIYQIDPY
FLERAEVLRGPSSVLYGKSNPGGVVALVSKRPTTESLREVQFKMGTDNLFQTGFDFGGAVDDDGVYSYRLTGLARDEDQQ
QVGEKSKRYAIAPSFSWRPDDRTSLTFLSSFQDDPDLGFYGWLPKEGTVQNGINGKLPTSFNDGEPGYNNISRKQQMVGY
AFEHGFDDVWTVRQNLRYSKMDLDYRSIYGQGISPTNPAELTRGVMNSKEHLSSFAVDTQAQAKFATGVVDHTLLMGVDY
MRMRNDVVYQYGTASPLNVVAPQYGNQNYTITGGASQVNRQEQTGLYVQDQAEWNQWVLTMGGRYDWSDTNSTNRLNQNS
VSKQKDNEFTGRAGLNYVFENGIAPYVSYSESFEPTSGTDFSGNTFAASKGKQYEAGVKFAPKDRPITASMAIYQLTKTN
NKVADPNPDHPFASVQGGEIRSRGVELEAKAALSANLNLLGSYTYTDAEYSKDTTLQGNTPAAIPKHMASLWADYTFHET
AISGLTLGSGVRYVGSSYGDEANTFKVKDYTVVDAAIKYDLARFNLPGSSIGINVNNLFDKEYVSSCFATYGCYWGAERQ
VVATATFRF
>Mature_728_residues
STKRLSSSGAKQGRTHVSGLAITIAAALGTLAMPAFSADTKEETLTVVGSSQPQQESAWGPVGTYVAKHSATGTKTDTPI
EKTPQSISVVTREEMDMRQPETVKGALAYSPGVMVGNRGASTAYDAVNIRGFSSVGTNMYLDGLKLQDDNYSIYQIDPYF
LERAEVLRGPSSVLYGKSNPGGVVALVSKRPTTESLREVQFKMGTDNLFQTGFDFGGAVDDDGVYSYRLTGLARDEDQQQ
VGEKSKRYAIAPSFSWRPDDRTSLTFLSSFQDDPDLGFYGWLPKEGTVQNGINGKLPTSFNDGEPGYNNISRKQQMVGYA
FEHGFDDVWTVRQNLRYSKMDLDYRSIYGQGISPTNPAELTRGVMNSKEHLSSFAVDTQAQAKFATGVVDHTLLMGVDYM
RMRNDVVYQYGTASPLNVVAPQYGNQNYTITGGASQVNRQEQTGLYVQDQAEWNQWVLTMGGRYDWSDTNSTNRLNQNSV
SKQKDNEFTGRAGLNYVFENGIAPYVSYSESFEPTSGTDFSGNTFAASKGKQYEAGVKFAPKDRPITASMAIYQLTKTNN
KVADPNPDHPFASVQGGEIRSRGVELEAKAALSANLNLLGSYTYTDAEYSKDTTLQGNTPAAIPKHMASLWADYTFHETA
ISGLTLGSGVRYVGSSYGDEANTFKVKDYTVVDAAIKYDLARFNLPGSSIGINVNNLFDKEYVSSCFATYGCYWGAERQV
VATATFRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=752, Percent_Identity=57.5797872340426, Blast_Score=842, Evalue=0.0,
Organism=Escherichia coli, GI1787024, Length=781, Percent_Identity=24.8399487836108, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1787344, Length=783, Percent_Identity=24.1379310344828, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1788478, Length=178, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79824; Mature: 79693

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKRLSSSGAKQGRTHVSGLAITIAAALGTLAMPAFSADTKEETLTVVGSSQPQQESAW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
GPVGTYVAKHSATGTKTDTPIEKTPQSISVVTREEMDMRQPETVKGALAYSPGVMVGNRG
CCHHHHHHHCCCCCCCCCCCHHHCCCCEEEEEHHHHCCCCCCHHCEEEEECCCEEECCCC
ASTAYDAVNIRGFSSVGTNMYLDGLKLQDDNYSIYQIDPYFLERAEVLRGPSSVLYGKSN
CCCCCCEEEECCCCCCCCCEEECCEEEECCCEEEEEECHHHHHHHHHHCCCCCEEECCCC
PGGVVALVSKRPTTESLREVQFKMGTDNLFQTGFDFGGAVDDDGVYSYRLTGLARDEDQQ
CCCEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHH
QVGEKSKRYAIAPSFSWRPDDRTSLTFLSSFQDDPDLGFYGWLPKEGTVQNGINGKLPTS
HHHHHHCCEEECCCCCCCCCCCCEEHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
FNDGEPGYNNISRKQQMVGYAFEHGFDDVWTVRQNLRYSKMDLDYRSIYGQGISPTNPAE
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCHHHHCCCCCCCCCHHH
LTRGVMNSKEHLSSFAVDTQAQAKFATGVVDHTLLMGVDYMRMRNDVVYQYGTASPLNVV
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEE
APQYGNQNYTITGGASQVNRQEQTGLYVQDQAEWNQWVLTMGGRYDWSDTNSTNRLNQNS
CCCCCCCCEEEECCHHHCCCHHHCCEEEEECCCCCEEEEEECCEECCCCCCCCCCCCCCC
VSKQKDNEFTGRAGLNYVFENGIAPYVSYSESFEPTSGTDFSGNTFAASKGKQYEAGVKF
CCHHCCCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCEE
APKDRPITASMAIYQLTKTNNKVADPNPDHPFASVQGGEIRSRGVELEAKAALSANLNLL
CCCCCCEEHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCEEE
GSYTYTDAEYSKDTTLQGNTPAAIPKHMASLWADYTFHETAISGLTLGSGVRYVGSSYGD
EEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHCCEEECCCHHHHCCCCCC
EANTFKVKDYTVVDAAIKYDLARFNLPGSSIGINVNNLFDKEYVSSCFATYGCYWGAERQ
CCCEEEEEEEEEEHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCE
VVATATFRF
EEEEEEECC
>Mature Secondary Structure 
STKRLSSSGAKQGRTHVSGLAITIAAALGTLAMPAFSADTKEETLTVVGSSQPQQESAW
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
GPVGTYVAKHSATGTKTDTPIEKTPQSISVVTREEMDMRQPETVKGALAYSPGVMVGNRG
CCHHHHHHHCCCCCCCCCCCHHHCCCCEEEEEHHHHCCCCCCHHCEEEEECCCEEECCCC
ASTAYDAVNIRGFSSVGTNMYLDGLKLQDDNYSIYQIDPYFLERAEVLRGPSSVLYGKSN
CCCCCCEEEECCCCCCCCCEEECCEEEECCCEEEEEECHHHHHHHHHHCCCCCEEECCCC
PGGVVALVSKRPTTESLREVQFKMGTDNLFQTGFDFGGAVDDDGVYSYRLTGLARDEDQQ
CCCEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHH
QVGEKSKRYAIAPSFSWRPDDRTSLTFLSSFQDDPDLGFYGWLPKEGTVQNGINGKLPTS
HHHHHHCCEEECCCCCCCCCCCCEEHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
FNDGEPGYNNISRKQQMVGYAFEHGFDDVWTVRQNLRYSKMDLDYRSIYGQGISPTNPAE
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCHHHHCCCCCCCCCHHH
LTRGVMNSKEHLSSFAVDTQAQAKFATGVVDHTLLMGVDYMRMRNDVVYQYGTASPLNVV
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEE
APQYGNQNYTITGGASQVNRQEQTGLYVQDQAEWNQWVLTMGGRYDWSDTNSTNRLNQNS
CCCCCCCCEEEECCHHHCCCHHHCCEEEEECCCCCEEEEEECCEECCCCCCCCCCCCCCC
VSKQKDNEFTGRAGLNYVFENGIAPYVSYSESFEPTSGTDFSGNTFAASKGKQYEAGVKF
CCHHCCCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCEE
APKDRPITASMAIYQLTKTNNKVADPNPDHPFASVQGGEIRSRGVELEAKAALSANLNLL
CCCCCCEEHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCEEE
GSYTYTDAEYSKDTTLQGNTPAAIPKHMASLWADYTFHETAISGLTLGSGVRYVGSSYGD
EEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHCCEEECCCHHHHCCCCCC
EANTFKVKDYTVVDAAIKYDLARFNLPGSSIGINVNNLFDKEYVSSCFATYGCYWGAERQ
CCCEEEEEEEEEEHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCE
VVATATFRF
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]