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The map label for this gene is gudP [H]

Identifier: 157372204

GI number: 157372204

Start: 4397790

End: 4399037

Strand: Direct

Name: gudP [H]

Synonym: Spro_3970

Alternate gene names: 157372204

Gene position: 4397790-4399037 (Clockwise)

Preceding gene: 157372189

Following gene: 157372208

Centisome position: 80.71

GC content: 59.38

Gene sequence:

>1248_bases
ATGGAGCGCATTGTGCAACAACGTCAACGCTGGTTCGGGGTTGTGGCCCTGCTGTTTTTGATCGTCATCGCCTATGCCGA
TCGGGTCAATATCGCCGTGATGCTGGTTAACCCCGACTTTCTGCAGCACTTTCAGCTCGGGGGAAACCGTGCGCATCAGG
GCATGCTGATGACGGTGTTTTTGCTCGGTTACGGGCTTTCCGCCATGCTGCTGACGCCGTTTCTGGAAACCCTGATGGGT
TATCGCCGTGCGCTGACGCTGAGCATTGTGCTATGGGCGTTGCTCACCGCCGCCTCGCCGCTGGCAGGGTCGCTGCTGCT
GTTATTTGCGGTGCGCGCATTGTTGGGTGCCAGTGAAGGCCCGTTGTTCTCGCTGAAAACCATGTATATCGGCGATCACT
TCGCTGCCGATGAGCGCGGCAAGCCCAATGCGGTCAGCACTCTGGGCGTCTCGCTGGGGCTGGTGATTGGCTTTCCGCTG
GTGAGCTTCTTGATGGCGCACTTCGGCTGGGCGGTTTCTTTCTATCTGCTGGCGCTGATCAACCTGTTGCTGGGGCTGGC
GTTGGTACGGCTGTTTATCCATCCCGCCGCATTGCCGCCGCGTGCCGTTGACCCAAGACCGATCCTGCAACGCGTCTGGG
ATACTTTTACCCTCGCCTGGCGCACCCCGATGCTCGGCTGGATCATGCTTATCGAGATCGCCACCCTCAGCTATCTGTGG
GGATCCAGCTCCTGGCTCCCGGCCTACCTGACCGACGAGAAAGGCTTTTCCATCAAACAGATGGGCTGGATGGCCTCCTT
GCCGTTTATCGTCAGCATTGCCTCTAAATATCTCGGCGGCGTACTGCTTGATCGCATCCGCCCTTATCAGGCACCGCTGA
TTTTCGCCTTTGGCGGTGCGGCAACGGCACTGTGCATCTATGGCGTGATGCATAGCGAACAGCTTGGCTGGATAGCCTTC
TTCCTGCTGGCGGCCAATGCCTGTTGGGGCGCTCAGGGAGCCGCGATCCCGACGCTGTTGCAGCATTATGCGCAGCCGCA
GGCCGTCGGCAGCGCCTATGGGCTGATTAACGGCATCGGCAATATGTTCTCGGCGTTTGTACCTATGATTATGGGCATGG
TGATGGCCAGCCAGGGCAAGGTGTCTTCGGGGTTTGCGGTGCTGATTGTGTCGCAGGTAGTGACACTGTTGGCGGGCGGC
GTGCTGTTCAGCCGGATGCTGATGACGCGTGAGGCAAGGCGGGCGTAA

Upstream 100 bases:

>100_bases
TTTACATTTAGATGACTCAACCCTGCTTTTCAGCACTGTGAAATCAGCGGGTTAGTTCTCTGCTGCCTGAATTCTTTAAC
CACCCGCCAAAGGAGCGCAG

Downstream 100 bases:

>100_bases
AAGGGTCGGGGCAGATAACGCGCCCCGACTCATATTCATGTTACTGCGGCTTAACGCCCTTTCTTTTTACGGCCAGGCTG
AGCGAAGCGCTTACGCGCAG

Product: major facilitator transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MERIVQQRQRWFGVVALLFLIVIAYADRVNIAVMLVNPDFLQHFQLGGNRAHQGMLMTVFLLGYGLSAMLLTPFLETLMG
YRRALTLSIVLWALLTAASPLAGSLLLLFAVRALLGASEGPLFSLKTMYIGDHFAADERGKPNAVSTLGVSLGLVIGFPL
VSFLMAHFGWAVSFYLLALINLLLGLALVRLFIHPAALPPRAVDPRPILQRVWDTFTLAWRTPMLGWIMLIEIATLSYLW
GSSSWLPAYLTDEKGFSIKQMGWMASLPFIVSIASKYLGGVLLDRIRPYQAPLIFAFGGAATALCIYGVMHSEQLGWIAF
FLLAANACWGAQGAAIPTLLQHYAQPQAVGSAYGLINGIGNMFSAFVPMIMGMVMASQGKVSSGFAVLIVSQVVTLLAGG
VLFSRMLMTREARRA

Sequences:

>Translated_415_residues
MERIVQQRQRWFGVVALLFLIVIAYADRVNIAVMLVNPDFLQHFQLGGNRAHQGMLMTVFLLGYGLSAMLLTPFLETLMG
YRRALTLSIVLWALLTAASPLAGSLLLLFAVRALLGASEGPLFSLKTMYIGDHFAADERGKPNAVSTLGVSLGLVIGFPL
VSFLMAHFGWAVSFYLLALINLLLGLALVRLFIHPAALPPRAVDPRPILQRVWDTFTLAWRTPMLGWIMLIEIATLSYLW
GSSSWLPAYLTDEKGFSIKQMGWMASLPFIVSIASKYLGGVLLDRIRPYQAPLIFAFGGAATALCIYGVMHSEQLGWIAF
FLLAANACWGAQGAAIPTLLQHYAQPQAVGSAYGLINGIGNMFSAFVPMIMGMVMASQGKVSSGFAVLIVSQVVTLLAGG
VLFSRMLMTREARRA
>Mature_415_residues
MERIVQQRQRWFGVVALLFLIVIAYADRVNIAVMLVNPDFLQHFQLGGNRAHQGMLMTVFLLGYGLSAMLLTPFLETLMG
YRRALTLSIVLWALLTAASPLAGSLLLLFAVRALLGASEGPLFSLKTMYIGDHFAADERGKPNAVSTLGVSLGLVIGFPL
VSFLMAHFGWAVSFYLLALINLLLGLALVRLFIHPAALPPRAVDPRPILQRVWDTFTLAWRTPMLGWIMLIEIATLSYLW
GSSSWLPAYLTDEKGFSIKQMGWMASLPFIVSIASKYLGGVLLDRIRPYQAPLIFAFGGAATALCIYGVMHSEQLGWIAF
FLLAANACWGAQGAAIPTLLQHYAQPQAVGSAYGLINGIGNMFSAFVPMIMGMVMASQGKVSSGFAVLIVSQVVTLLAGG
VLFSRMLMTREARRA

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI2367379, Length=399, Percent_Identity=25.8145363408521, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082320, Length=435, Percent_Identity=24.367816091954, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789515, Length=418, Percent_Identity=22.9665071770335, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=20.7762557077626, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45251; Mature: 45251

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIVQQRQRWFGVVALLFLIVIAYADRVNIAVMLVNPDFLQHFQLGGNRAHQGMLMTVF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCCCCHHHHHHHHHHH
LLGYGLSAMLLTPFLETLMGYRRALTLSIVLWALLTAASPLAGSLLLLFAVRALLGASEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
PLFSLKTMYIGDHFAADERGKPNAVSTLGVSLGLVIGFPLVSFLMAHFGWAVSFYLLALI
CEEEEEHEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLGLALVRLFIHPAALPPRAVDPRPILQRVWDTFTLAWRTPMLGWIMLIEIATLSYLW
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSSSWLPAYLTDEKGFSIKQMGWMASLPFIVSIASKYLGGVLLDRIRPYQAPLIFAFGGA
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHH
ATALCIYGVMHSEQLGWIAFFLLAANACWGAQGAAIPTLLQHYAQPQAVGSAYGLINGIG
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
NMFSAFVPMIMGMVMASQGKVSSGFAVLIVSQVVTLLAGGVLFSRMLMTREARRA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERIVQQRQRWFGVVALLFLIVIAYADRVNIAVMLVNPDFLQHFQLGGNRAHQGMLMTVF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCCCCHHHHHHHHHHH
LLGYGLSAMLLTPFLETLMGYRRALTLSIVLWALLTAASPLAGSLLLLFAVRALLGASEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
PLFSLKTMYIGDHFAADERGKPNAVSTLGVSLGLVIGFPLVSFLMAHFGWAVSFYLLALI
CEEEEEHEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLGLALVRLFIHPAALPPRAVDPRPILQRVWDTFTLAWRTPMLGWIMLIEIATLSYLW
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSSSWLPAYLTDEKGFSIKQMGWMASLPFIVSIASKYLGGVLLDRIRPYQAPLIFAFGGA
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHH
ATALCIYGVMHSEQLGWIAFFLLAANACWGAQGAAIPTLLQHYAQPQAVGSAYGLINGIG
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
NMFSAFVPMIMGMVMASQGKVSSGFAVLIVSQVVTLLAGGVLFSRMLMTREARRA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]