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The map label for this gene is rof [H]

Identifier: 157371998

GI number: 157371998

Start: 4158116

End: 4158379

Strand: Direct

Name: rof [H]

Synonym: Spro_3763

Alternate gene names: 157371998

Gene position: 4158116-4158379 (Clockwise)

Preceding gene: 157371997

Following gene: 157372007

Centisome position: 76.31

GC content: 49.62

Gene sequence:

>264_bases
ATGTTGATGAATGATGAGTACCAATCCATCAATTGCGATGACTATGAAAGCCTGGAACTCGCCTGTCAGCATAACTACAT
TCTGAAGCTGGAGTTACGCGACGGAGAAAAATTCGAAGGCAAAGCCACCGAGCTGAAGTTTACCAAGGGCGTTGAGTACC
TGATTATCGATCGGGCCGGCGACGCTCTCAGCTTGCGTCTGGATCACATCCTCAGTTTCAGTCATCCGGAAATCGGTACC
GTGGTCGTCAGCCTGTCTGATTGA

Upstream 100 bases:

>100_bases
GTATTAAAGGCATTGGACGAAGTTGCTGCGAATAGCACGCTACCGTCCTCCGTTAGGGAACAGGCGGCCTTTGCCGCCGC
TAACTTATTGGTGAGCGACT

Downstream 100 bases:

>100_bases
TTTAGCGGTAACGCCATCCCAACAGGGCAGCCCAACGGCTGCCCTCGTCATTTATGGTTTGAGGCTGGCTAGGGTTTGAG
ACTGGCCTAGGGTTTGAGGC

Product: transcriptional antiterminator, Rof

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MLMNDEYQSINCDDYESLELACQHNYILKLELRDGEKFEGKATELKFTKGVEYLIIDRAGDALSLRLDHILSFSHPEIGT
VVVSLSD

Sequences:

>Translated_87_residues
MLMNDEYQSINCDDYESLELACQHNYILKLELRDGEKFEGKATELKFTKGVEYLIIDRAGDALSLRLDHILSFSHPEIGT
VVVSLSD
>Mature_87_residues
MLMNDEYQSINCDDYESLELACQHNYILKLELRDGEKFEGKATELKFTKGVEYLIIDRAGDALSLRLDHILSFSHPEIGT
VVVSLSD

Specific function: Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination [H]

COG id: COG4568

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081698, Length=84, Percent_Identity=65.4761904761905, Blast_Score=117, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002730
- InterPro:   IPR009778 [H]

Pfam domain/function: PF07073 ROF [H]

EC number: NA

Molecular weight: Translated: 9909; Mature: 9909

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMNDEYQSINCDDYESLELACQHNYILKLELRDGEKFEGKATELKFTKGVEYLIIDRAG
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCC
DALSLRLDHILSFSHPEIGTVVVSLSD
CEEEEEEEHEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MLMNDEYQSINCDDYESLELACQHNYILKLELRDGEKFEGKATELKFTKGVEYLIIDRAG
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCC
DALSLRLDHILSFSHPEIGTVVVSLSD
CEEEEEEEHEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9723924; 9278503 [H]