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The map label for this gene is metI [H]

Identifier: 157371989

GI number: 157371989

Start: 4151240

End: 4151893

Strand: Direct

Name: metI [H]

Synonym: Spro_3754

Alternate gene names: 157371989

Gene position: 4151240-4151893 (Clockwise)

Preceding gene: 157371988

Following gene: 157371990

Centisome position: 76.19

GC content: 55.66

Gene sequence:

>654_bases
ATGTCTGAGGCAATGATGTGGTTAATGGCTCGTGGCGTGTGGGAAACCGTCATGATGACCTTTGTCTCCGGCTTTTTCGG
TTTCGTACTCGGCCTGCCGGTTGGCGTGCTGCTGTATGTGACCCGCCCGGGGCAAATCGCCGCCAACAACACGCTATATA
GGACGCTGTCCGGGCTGGTGAACGTTTTCCGTTCCATTCCGTTCATTATTCTGTTGGTGTGGATGATTCCATTTACTCGT
TTGATCGTCGGTACCTCGATCGGCCTGCAGGCAGCTATCGTGCCACTGACCGTGGGCGCTGCGCCGTTTATTGCCCGTAT
GGTGGAAAACGCCCTGCTGGAGATCCCCTCAGGTCTGGTGGAGGCAGCCCGCGCTATGGGGGCGACCCCGATGCAAATCA
TCAAGAAGGTGCTGCTGCCGGAAGCCCTGCCGGGCCTGGTTAACGCCGCCACTATCACCTTGATCACTTTGGTGGGTTAT
TCCGCCATGGGTGGCGCAGTCGGCGCAGGCGGTCTGGGACAGATTGGCTATCAGTACGGTTATATCGGTTATAACGCCAC
AGTAATGAATACCGTATTAGTATTACTGGTGGTGCTGGTCTATCTGATTCAGTTCTTCGGTGATCGGATCGTCAAGGCCG
TCACCCATAAGTAG

Upstream 100 bases:

>100_bases
TTCGGCGTGATGTTGGCAGAGCTGCATGGCAGTGATGAAGACGCGCTGGCAACGATTAAGTTCCTGCAGGAAAATCAGGT
AAAAGTAGAGGTTCTGGGTT

Downstream 100 bases:

>100_bases
TTTTACAGCAACTGCGCTCACACAGCGTATTTCAAATGCGAGTCTAATGAGGAAGGGATATGTCGTTAAAATTTAAATCC
ATCGCGGCAATCGGCGCACT

Product: DL-methionine transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSEAMMWLMARGVWETVMMTFVSGFFGFVLGLPVGVLLYVTRPGQIAANNTLYRTLSGLVNVFRSIPFIILLVWMIPFTR
LIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLVEAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGY
SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQFFGDRIVKAVTHK

Sequences:

>Translated_217_residues
MSEAMMWLMARGVWETVMMTFVSGFFGFVLGLPVGVLLYVTRPGQIAANNTLYRTLSGLVNVFRSIPFIILLVWMIPFTR
LIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLVEAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGY
SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQFFGDRIVKAVTHK
>Mature_216_residues
SEAMMWLMARGVWETVMMTFVSGFFGFVLGLPVGVLLYVTRPGQIAANNTLYRTLSGLVNVFRSIPFIILLVWMIPFTRL
IVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLVEAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGYS
AMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQFFGDRIVKAVTHK

Specific function: Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl- methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=217, Percent_Identity=89.4009216589862, Blast_Score=338, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23197; Mature: 23066

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAMMWLMARGVWETVMMTFVSGFFGFVLGLPVGVLLYVTRPGQIAANNTLYRTLSGLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHH
NVFRSIPFIILLVWMIPFTRLIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
EAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQYG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
YIGYNATVMNTVLVLLVVLVYLIQFFGDRIVKAVTHK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEAMMWLMARGVWETVMMTFVSGFFGFVLGLPVGVLLYVTRPGQIAANNTLYRTLSGLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHH
NVFRSIPFIILLVWMIPFTRLIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
EAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQYG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
YIGYNATVMNTVLVLLVVLVYLIQFFGDRIVKAVTHK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]