| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
Click here to switch to the map view.
The map label for this gene is pbpC [H]
Identifier: 157371849
GI number: 157371849
Start: 3993411
End: 3995735
Strand: Reverse
Name: pbpC [H]
Synonym: Spro_3614
Alternate gene names: 157371849
Gene position: 3995735-3993411 (Counterclockwise)
Preceding gene: 157371850
Following gene: 157371848
Centisome position: 73.33
GC content: 63.48
Gene sequence:
>2325_bases ATGAATCGACTTCTTACTCATTTACGTCGCCGGGCAGCCATCTGGCTGCTGGCTATTTTGCTGCCGCCCGTTTTGCTGTG GTTGGCGGACCGGCTGTGGCCGTTGCCGCTGAAAGATGCCGAGATGGCACGAGTGGTGGTGGCGGAAGACGGTACCCCGC TGTGGCGCTATGCGGACAGTGACGGCGTATGGCGCTATCCGGTCAGTCTGCAGCAGGTCTCGCCCTATTATTTGCAGGCG CTGCTGACCTATGAAGACCGTTGGTTTTATCGGCACCCCGGCATCAATCCATTGTCGCTGGCCCGTGCCGCCTGGCAGGA CCTGCGCAACGGGCAGATCGTTTCCGGCGGCAGCACGCTGTCGATGCAGGTCGCGCGCCTGATTGATCCCCATCCACGCA CTCTGGCCGGCAAGTTACGCCAGGTGTGGCGTACCGCCCAGTTGGAATGGCATCTGTCGAAGGATCAAATCCTTGAAATC TACCTTAACCGGGCACCTTACGGCGGCACGCTACAGGGGATTGGCGCGGCCAGCTGGACTTATTTGGGCAAACCGCCTTC GGCGCTGACGCGTGGTGAGGCGGCGTTGCTGGCGGTATTGCCGCAGGCTCCCAGCCGTTTGCGGCCGGACCGCTACCCGG AACGGGCGCAGGCTGCGCGTGACAAGGTGCTGGAACGCCTGGCGTATTATCAGGTTTGGCCAGCGCAGCAGGTGGCCGAA ATCCGGCAGGAAGCGTTGTGGCTGGCCCCGCGGCAGGTACCGCAGTTGGCCCCGTTACTGGCAAGGCGCATGACACAGGG CAATCGTAGCCAGGTGGTGACCACCACGCTGGACGCTACCTTGCAGCGGCGGCTGGAAGAACTGGCTCGCGGCTGGAAGA GTCAACTGCCGGAAAAAACCTCGGTTGGCGTATTGGTGGTTGATCACACCAATATGAAAGTACGTGCCTACCTGGGCTCG CTGGATTTGAACGATAACAGCCGTTTTGGCCATGTCGACATGGTGGCTGCCTGGCGTTCGCCGGGCTCGACGCTAAAACC CTTTTTGTATGGTTTGGCGTTGGACGACGGCCTGATCCACGCCGAATCGCTTTTGCAGGACATACCGCGCCGTTTTGGGG ATTATCGGCCCGGTAATTTTGATACCGGTTTCCACGGCCCGGTCAGCGCCAGTGAAGCGTTGTCGCGTTCACTCAACCTG CCGGCGGTCCAGTTGCTGGAAGCCTACGGGCCGAAGCGCTTTGCCGCCAATCTCCGTAACGTGGGGGTTGAACTGCGGCT GCCGGCACACGCCGAACCCAGCCTGGCGCTGATCCTGGGCGGGGCCGGAGCCAGACTGGATCAGTTGGTGGCCGGGTTCA GCGCGCTGGCTCGTCAGGGCCGGGTGGCACCGCTGCGCTTTACGCCTCAGCAAGGGATTTACGATCGCCAGTTCATGTCG CCGGGCGCCGCCTGGATTGTACGGCGAATATTGGCGGGAGAGGCACGTCCATTGCCGGATGATGCATTGCCTGCCAGTGT GCCACTGGCGTGGAAGACCGGCACCAGTTATGGCTACCGCGACGCCTGGGCCATCGGCGTTAATGCGCGCTATACGATAG GCATTTGGGTGGGGCGACCGGACGGTACTCCGGTGGCCGGGCAGTTCGGCTTCGCTACCGCGGTGCCGCTGCTTAATCAG GTCAATAACCTGTTGCTGACCTCTTTACGCCAGCGTGGGGAAGGCATTCCGGCCGATCCGCGCCCCGCCAGCGTCAGCCG TGCGGTGATCTGCTGGCCGGGCGGCCAGCCACTGCCCGCGGGTGACAGCAATTGCCGCCAACGACGTCTGAGTTGGACTC TCGACGGGACTATTCCGCCCACGCTGCCCGCACCGGGTCAGGAAAGCGTGCTGGGCAGCCAGCCGCTGATGTGGTTGAAC GCGCGCGGATTGCGGGTTGCAGCGGATTGCCCGGGGGCGACACCGCGTCGGCTGGCCCTGTGGCCTACGCCGCTGGAGCC CTGGTTGCCTCCGGCGGAGCGTCGTGCGCAGCGCTTGCCGGCTATTGATCCGCAGTGCCCGCCGTTGCAGCAGCAAGAAG CACCGCCGCTGTTGATGCTGGGCGTGCGTGACGGCGCGATACTGCGTCGCCTGCCGGGCAATAATACGCTGGACTTGCGG GTCAGCGCCCAGGGCGGCGGCGGACAGCGCTGGTGGTTCCTTAACGGCCAGTTGGTGGGGGAAGGGGAGTCGCTGCTACA GACGCTGACCCAACCTGGTCGCTATCAGCTCAGCGTGCTGGATGAGAGCGGTCAGGTGGCATTGCGCGAATTTAGCCTCG ATTAA
Upstream 100 bases:
>100_bases CTGGGCGCGACACCACAGCGGCTTGAAATTGCCAAATGATCCTCTTTGCCCCGCCCCGGTGATTTAGCCGGTGGCGGGGC AAAGGGGTGATACCTTCCTG
Downstream 100 bases:
>100_bases GGTAAGTTTTCATAACCTGTGCTCTGGGCCGCAAAGTGAAGAATAAAGATAATGATTTTTTAATGAAATGTTGATTTTCC CGTAGGCAAGCGTTGGCAGC
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 774; Mature: 774
Protein sequence:
>774_residues MNRLLTHLRRRAAIWLLAILLPPVLLWLADRLWPLPLKDAEMARVVVAEDGTPLWRYADSDGVWRYPVSLQQVSPYYLQA LLTYEDRWFYRHPGINPLSLARAAWQDLRNGQIVSGGSTLSMQVARLIDPHPRTLAGKLRQVWRTAQLEWHLSKDQILEI YLNRAPYGGTLQGIGAASWTYLGKPPSALTRGEAALLAVLPQAPSRLRPDRYPERAQAARDKVLERLAYYQVWPAQQVAE IRQEALWLAPRQVPQLAPLLARRMTQGNRSQVVTTTLDATLQRRLEELARGWKSQLPEKTSVGVLVVDHTNMKVRAYLGS LDLNDNSRFGHVDMVAAWRSPGSTLKPFLYGLALDDGLIHAESLLQDIPRRFGDYRPGNFDTGFHGPVSASEALSRSLNL PAVQLLEAYGPKRFAANLRNVGVELRLPAHAEPSLALILGGAGARLDQLVAGFSALARQGRVAPLRFTPQQGIYDRQFMS PGAAWIVRRILAGEARPLPDDALPASVPLAWKTGTSYGYRDAWAIGVNARYTIGIWVGRPDGTPVAGQFGFATAVPLLNQ VNNLLLTSLRQRGEGIPADPRPASVSRAVICWPGGQPLPAGDSNCRQRRLSWTLDGTIPPTLPAPGQESVLGSQPLMWLN ARGLRVAADCPGATPRRLALWPTPLEPWLPPAERRAQRLPAIDPQCPPLQQQEAPPLLMLGVRDGAILRRLPGNNTLDLR VSAQGGGGQRWWFLNGQLVGEGESLLQTLTQPGRYQLSVLDESGQVALREFSLD
Sequences:
>Translated_774_residues MNRLLTHLRRRAAIWLLAILLPPVLLWLADRLWPLPLKDAEMARVVVAEDGTPLWRYADSDGVWRYPVSLQQVSPYYLQA LLTYEDRWFYRHPGINPLSLARAAWQDLRNGQIVSGGSTLSMQVARLIDPHPRTLAGKLRQVWRTAQLEWHLSKDQILEI YLNRAPYGGTLQGIGAASWTYLGKPPSALTRGEAALLAVLPQAPSRLRPDRYPERAQAARDKVLERLAYYQVWPAQQVAE IRQEALWLAPRQVPQLAPLLARRMTQGNRSQVVTTTLDATLQRRLEELARGWKSQLPEKTSVGVLVVDHTNMKVRAYLGS LDLNDNSRFGHVDMVAAWRSPGSTLKPFLYGLALDDGLIHAESLLQDIPRRFGDYRPGNFDTGFHGPVSASEALSRSLNL PAVQLLEAYGPKRFAANLRNVGVELRLPAHAEPSLALILGGAGARLDQLVAGFSALARQGRVAPLRFTPQQGIYDRQFMS PGAAWIVRRILAGEARPLPDDALPASVPLAWKTGTSYGYRDAWAIGVNARYTIGIWVGRPDGTPVAGQFGFATAVPLLNQ VNNLLLTSLRQRGEGIPADPRPASVSRAVICWPGGQPLPAGDSNCRQRRLSWTLDGTIPPTLPAPGQESVLGSQPLMWLN ARGLRVAADCPGATPRRLALWPTPLEPWLPPAERRAQRLPAIDPQCPPLQQQEAPPLLMLGVRDGAILRRLPGNNTLDLR VSAQGGGGQRWWFLNGQLVGEGESLLQTLTQPGRYQLSVLDESGQVALREFSLD >Mature_774_residues MNRLLTHLRRRAAIWLLAILLPPVLLWLADRLWPLPLKDAEMARVVVAEDGTPLWRYADSDGVWRYPVSLQQVSPYYLQA LLTYEDRWFYRHPGINPLSLARAAWQDLRNGQIVSGGSTLSMQVARLIDPHPRTLAGKLRQVWRTAQLEWHLSKDQILEI YLNRAPYGGTLQGIGAASWTYLGKPPSALTRGEAALLAVLPQAPSRLRPDRYPERAQAARDKVLERLAYYQVWPAQQVAE IRQEALWLAPRQVPQLAPLLARRMTQGNRSQVVTTTLDATLQRRLEELARGWKSQLPEKTSVGVLVVDHTNMKVRAYLGS LDLNDNSRFGHVDMVAAWRSPGSTLKPFLYGLALDDGLIHAESLLQDIPRRFGDYRPGNFDTGFHGPVSASEALSRSLNL PAVQLLEAYGPKRFAANLRNVGVELRLPAHAEPSLALILGGAGARLDQLVAGFSALARQGRVAPLRFTPQQGIYDRQFMS PGAAWIVRRILAGEARPLPDDALPASVPLAWKTGTSYGYRDAWAIGVNARYTIGIWVGRPDGTPVAGQFGFATAVPLLNQ VNNLLLTSLRQRGEGIPADPRPASVSRAVICWPGGQPLPAGDSNCRQRRLSWTLDGTIPPTLPAPGQESVLGSQPLMWLN ARGLRVAADCPGATPRRLALWPTPLEPWLPPAERRAQRLPAIDPQCPPLQQQEAPPLLMLGVRDGAILRRLPGNNTLDLR VSAQGGGGQRWWFLNGQLVGEGESLLQTLTQPGRYQLSVLDESGQVALREFSLD
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=777, Percent_Identity=63.5778635778636, Blast_Score=1002, Evalue=0.0, Organism=Escherichia coli, GI87082258, Length=225, Percent_Identity=36, Blast_Score=125, Evalue=7e-30, Organism=Escherichia coli, GI1786343, Length=521, Percent_Identity=27.2552783109405, Blast_Score=105, Evalue=2e-23, Organism=Escherichia coli, GI1789601, Length=189, Percent_Identity=34.9206349206349, Blast_Score=79, Evalue=1e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 85498; Mature: 85498
Theoretical pI: Translated: 10.31; Mature: 10.31
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRLLTHLRRRAAIWLLAILLPPVLLWLADRLWPLPLKDAEMARVVVAEDGTPLWRYADS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECC DGVWRYPVSLQQVSPYYLQALLTYEDRWFYRHPGINPLSLARAAWQDLRNGQIVSGGSTL CCEEECCCCHHHCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCHH SMQVARLIDPHPRTLAGKLRQVWRTAQLEWHLSKDQILEIYLNRAPYGGTLQGIGAASWT HHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCHHHEEEHHCCCCCCCCCCCCCCCCCEE YLGKPPSALTRGEAALLAVLPQAPSRLRPDRYPERAQAARDKVLERLAYYQVWPAQQVAE ECCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH IRQEALWLAPRQVPQLAPLLARRMTQGNRSQVVTTTLDATLQRRLEELARGWKSQLPEKT HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC SVGVLVVDHTNMKVRAYLGSLDLNDNSRFGHVDMVAAWRSPGSTLKPFLYGLALDDGLIH CCEEEEEECCCEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHECCCCHHH AESLLQDIPRRFGDYRPGNFDTGFHGPVSASEALSRSLNLPAVQLLEAYGPKRFAANLRN HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH VGVELRLPAHAEPSLALILGGAGARLDQLVAGFSALARQGRVAPLRFTPQQGIYDRQFMS CCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCC PGAAWIVRRILAGEARPLPDDALPASVPLAWKTGTSYGYRDAWAIGVNARYTIGIWVGRP CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEEECC DGTPVAGQFGFATAVPLLNQVNNLLLTSLRQRGEGIPADPRPASVSRAVICWPGGQPLPA CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCC GDSNCRQRRLSWTLDGTIPPTLPAPGQESVLGSQPLMWLNARGLRVAADCPGATPRRLAL CCCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEEE WPTPLEPWLPPAERRAQRLPAIDPQCPPLQQQEAPPLLMLGVRDGAILRRLPGNNTLDLR CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHEEECCCCCEEEEE VSAQGGGGQRWWFLNGQLVGEGESLLQTLTQPGRYQLSVLDESGQVALREFSLD EEECCCCCCEEEEECCEEECCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCC >Mature Secondary Structure MNRLLTHLRRRAAIWLLAILLPPVLLWLADRLWPLPLKDAEMARVVVAEDGTPLWRYADS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECC DGVWRYPVSLQQVSPYYLQALLTYEDRWFYRHPGINPLSLARAAWQDLRNGQIVSGGSTL CCEEECCCCHHHCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCHH SMQVARLIDPHPRTLAGKLRQVWRTAQLEWHLSKDQILEIYLNRAPYGGTLQGIGAASWT HHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCHHHEEEHHCCCCCCCCCCCCCCCCCEE YLGKPPSALTRGEAALLAVLPQAPSRLRPDRYPERAQAARDKVLERLAYYQVWPAQQVAE ECCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH IRQEALWLAPRQVPQLAPLLARRMTQGNRSQVVTTTLDATLQRRLEELARGWKSQLPEKT HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC SVGVLVVDHTNMKVRAYLGSLDLNDNSRFGHVDMVAAWRSPGSTLKPFLYGLALDDGLIH CCEEEEEECCCEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHECCCCHHH AESLLQDIPRRFGDYRPGNFDTGFHGPVSASEALSRSLNLPAVQLLEAYGPKRFAANLRN HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH VGVELRLPAHAEPSLALILGGAGARLDQLVAGFSALARQGRVAPLRFTPQQGIYDRQFMS CCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCC PGAAWIVRRILAGEARPLPDDALPASVPLAWKTGTSYGYRDAWAIGVNARYTIGIWVGRP CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEEECC DGTPVAGQFGFATAVPLLNQVNNLLLTSLRQRGEGIPADPRPASVSRAVICWPGGQPLPA CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCC GDSNCRQRRLSWTLDGTIPPTLPAPGQESVLGSQPLMWLNARGLRVAADCPGATPRRLAL CCCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEEE WPTPLEPWLPPAERRAQRLPAIDPQCPPLQQQEAPPLLMLGVRDGAILRRLPGNNTLDLR CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHEEECCCCCEEEEE VSAQGGGGQRWWFLNGQLVGEGESLLQTLTQPGRYQLSVLDESGQVALREFSLD EEECCCCCCEEEEECCEEECCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]