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The map label for this gene is ttdR [H]

Identifier: 157371671

GI number: 157371671

Start: 3805335

End: 3806294

Strand: Direct

Name: ttdR [H]

Synonym: Spro_3434

Alternate gene names: 157371671

Gene position: 3805335-3806294 (Clockwise)

Preceding gene: 157371667

Following gene: 157371674

Centisome position: 69.84

GC content: 59.17

Gene sequence:

>960_bases
ATGCGCCAGACGGAGAACCTGGTATTCATAAGAAACGCTTTTGCATATAATGCAAAAATGAATGACGCCCGTTATGTTGA
ACATCTGCCGATATTTCTCGAGGTGGCCCTGTTGGGCAGCTTCTCCGCCGCCGCCCGCAAACTGGGAATGGTGCCTTCGT
CCCTGGTACGCCACGTCGATGCGCTGGAAAGTGCCCTGGACGCTACGCTGTTTATCCGTTCAACACGCGGCCTGATGCTG
ACGGACGCCGGAGAAATGCTGCAGGCGCGCGCGGCAACGCTGCTTTCGGACATCAGCGATATCCGCGCCGAACTGGCTTC
ACTTAGCGACAGGCCGCAAGGCACGCTACGCATCAGTTGTCTGCCGACCTTCGGCAAAACCTATATCCTGCCGCTGTTGC
CTCTGCTTGCTGAACGTTATCCGCAGCTGTTTGTTGAACTGGATTTGACGGAGCGCCAGACCGATCCGACGCAGGAATTG
CTGGATGCCGCCATTCGCATCGGCGAGCAGAAAGACAGTGGGTTGTACGCCAGCCGGATAGCCACCCAGCGCTGGGTGAT
GTGCGCCAGCCCGGCTTATCTCGCCCGTTATGGCAGGCCTGCCGATCTGAACGCGTTGCCGGAGCATCGGCTGATTGCCC
GCTACCACAAGCAACAGCCAGCCTGCTGGGCGCAAATTCTCAGCGCCCCCTTGATGGACCGCTGCAGCCTGGTATTGCGC
TGTGACGACTTTACCGCTCAACGCGAGGCGGCGCTGTTGGGGTTGGGGATCACCTTTTTACCCAATTGGGTGGTCGGCCC
GGATATACAGGCTGGTCGGTTGCTGCCGGTGCTCGAGGATCCGCGTCAGGAGCAACAGGGGATTTATCTGCTGCGCCCGG
TGGCAAAGGTGTCGGCACGGCTTAACCTGTTCATCACGTTGCTCAAGCAAAGTATCGGTCAGCCCCCGAGCTGGGAGTGA

Upstream 100 bases:

>100_bases
CTAACGTTCTAAAAACCGCGTGCTTTATGCATTATTGCTCTGCGCGGTGAGATCACGGCACGTTGTTACTCGCCGTAAGC
TCCCAAAAAGAGTAGCCGTA

Downstream 100 bases:

>100_bases
AGCGGTGATACCCGGCCATACAACGCCGGGTTGTCGCTTTCGTCTTTCAGGTCTATTCCGGTCAGGCGACGCTGGAAAGC
CTGTTCCAGCAGCCACGCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRQTENLVFIRNAFAYNAKMNDARYVEHLPIFLEVALLGSFSAAARKLGMVPSSLVRHVDALESALDATLFIRSTRGLML
TDAGEMLQARAATLLSDISDIRAELASLSDRPQGTLRISCLPTFGKTYILPLLPLLAERYPQLFVELDLTERQTDPTQEL
LDAAIRIGEQKDSGLYASRIATQRWVMCASPAYLARYGRPADLNALPEHRLIARYHKQQPACWAQILSAPLMDRCSLVLR
CDDFTAQREAALLGLGITFLPNWVVGPDIQAGRLLPVLEDPRQEQQGIYLLRPVAKVSARLNLFITLLKQSIGQPPSWE

Sequences:

>Translated_319_residues
MRQTENLVFIRNAFAYNAKMNDARYVEHLPIFLEVALLGSFSAAARKLGMVPSSLVRHVDALESALDATLFIRSTRGLML
TDAGEMLQARAATLLSDISDIRAELASLSDRPQGTLRISCLPTFGKTYILPLLPLLAERYPQLFVELDLTERQTDPTQEL
LDAAIRIGEQKDSGLYASRIATQRWVMCASPAYLARYGRPADLNALPEHRLIARYHKQQPACWAQILSAPLMDRCSLVLR
CDDFTAQREAALLGLGITFLPNWVVGPDIQAGRLLPVLEDPRQEQQGIYLLRPVAKVSARLNLFITLLKQSIGQPPSWE
>Mature_319_residues
MRQTENLVFIRNAFAYNAKMNDARYVEHLPIFLEVALLGSFSAAARKLGMVPSSLVRHVDALESALDATLFIRSTRGLML
TDAGEMLQARAATLLSDISDIRAELASLSDRPQGTLRISCLPTFGKTYILPLLPLLAERYPQLFVELDLTERQTDPTQEL
LDAAIRIGEQKDSGLYASRIATQRWVMCASPAYLARYGRPADLNALPEHRLIARYHKQQPACWAQILSAPLMDRCSLVLR
CDDFTAQREAALLGLGITFLPNWVVGPDIQAGRLLPVLEDPRQEQQGIYLLRPVAKVSARLNLFITLLKQSIGQPPSWE

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=28.476821192053, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=29.9003322259136, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=28.2312925170068, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789639, Length=265, Percent_Identity=31.6981132075472, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=29.5373665480427, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=30.5555555555556, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=29.8245614035088, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789173, Length=276, Percent_Identity=24.6376811594203, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786508, Length=275, Percent_Identity=26.9090909090909, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI157672245, Length=134, Percent_Identity=34.3283582089552, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=273, Percent_Identity=26.3736263736264, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35610; Mature: 35610

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTENLVFIRNAFAYNAKMNDARYVEHLPIFLEVALLGSFSAAARKLGMVPSSLVRHVD
CCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
ALESALDATLFIRSTRGLMLTDAGEMLQARAATLLSDISDIRAELASLSDRPQGTLRISC
HHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LPTFGKTYILPLLPLLAERYPQLFVELDLTERQTDPTQELLDAAIRIGEQKDSGLYASRI
ECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
ATQRWVMCASPAYLARYGRPADLNALPEHRLIARYHKQQPACWAQILSAPLMDRCSLVLR
HHHHHEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHCEEEEE
CDDFTAQREAALLGLGITFLPNWVVGPDIQAGRLLPVLEDPRQEQQGIYLLRPVAKVSAR
ECCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHH
LNLFITLLKQSIGQPPSWE
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRQTENLVFIRNAFAYNAKMNDARYVEHLPIFLEVALLGSFSAAARKLGMVPSSLVRHVD
CCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
ALESALDATLFIRSTRGLMLTDAGEMLQARAATLLSDISDIRAELASLSDRPQGTLRISC
HHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LPTFGKTYILPLLPLLAERYPQLFVELDLTERQTDPTQELLDAAIRIGEQKDSGLYASRI
ECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
ATQRWVMCASPAYLARYGRPADLNALPEHRLIARYHKQQPACWAQILSAPLMDRCSLVLR
HHHHHEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHCEEEEE
CDDFTAQREAALLGLGITFLPNWVVGPDIQAGRLLPVLEDPRQEQQGIYLLRPVAKVSAR
ECCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHH
LNLFITLLKQSIGQPPSWE
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]