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The map label for this gene is fepD [H]

Identifier: 157371661

GI number: 157371661

Start: 3789533

End: 3790606

Strand: Direct

Name: fepD [H]

Synonym: Spro_3424

Alternate gene names: 157371661

Gene position: 3789533-3790606 (Clockwise)

Preceding gene: 157371659

Following gene: 157371662

Centisome position: 69.55

GC content: 61.27

Gene sequence:

>1074_bases
ATGTTACGGATTACACGCCCAGGCACACAGCCCGTCCCCGCTCCCCAGGAGCGTCTTATTGGCGGCACTTCCCGTTCATT
TCGTCGCAGGCTTTTTGGCCTGCTGATTGCCGTTGGTGCGCTGCTGATCGTTATGCTGCTCAGCCTGTCACTCGGCGCTA
AATCTATTCCCTTCGACACGGTGATCCAGGCGCTGAAAGGCCAGTGCAGCGGTGCTGACTGCACCATCATCACCAACGCC
CGGCTGCCACGTACGCTGGTTGGCATTCTGGCCGGTATTGCGCTGGGCCTGTCCGGCGTGCTGATGCAAACCCTCACCCG
CAACCCGCTGGCCGATCCGGGTATTCTCGGGGTTAACGCCGGAGCAGGCTTTGCCGTGGTGCTGGGGATCACTTTCTTTG
GTGCCGTCGACGTCAGCCAATATCTGTGGTTCGCCTTTGCCGGCGCGATGTTTGCTGCACTGCTGGTGGCGCTAATCGGC
GCTCTGGGTGGCAGCAGCCTCAACCCGGTGCGTCTGACGCTGGCCGGTGTCGCGCTGGCGGCGGTGCTGGAAGGCATGAC
CTCCGGGATTTCCCTGTTGAATCCACTGGTTTTCGACCAGCTCCGTTTTTGGCAGGCCGGTTCGCTGGATATTCAAAATA
TGCAGGTGGTGCGCACCGTCGCCCTGCCGATCCTGTTGGGCACGCTGATTACGCTGTGGATGAGCAAGTCGCTGAACAGC
CTGAGCATGGGTAATGAATTGGCTACCGCGCTGGGTACCGGCATTGTTCGTACTCAGTTGCTGGGCCTGCTGGCGATTAC
TCTGCTGTGCGGCGGGGCTACCGCGGCCGTCGGCCCGATAGCCTTTGTCGGCCTGATGATGCCGCACATCGCCCGGCGGC
TGGGCGGTTCCGAACTGCATTGGATGCTGCCATGGACGCTGGTACTGACCCCCATCCTGCTGTTGAGCGCCGATTTGATC
GGTCGCTTCCTGGTGGCCGGTGAACTGCGTGTGTCCATCGTCACCGCCCTGATTGGCGCCCCACTGCTGATCATGCTGGT
GCGACAACGTCATATGTTCAGGAGGCAGCGCTAA

Upstream 100 bases:

>100_bases
CGTCTGGGCTGCAATAGCGAAGGGACTCATGGTACCATAGATGAAAGCAATCAATAATGATAATAAAACTCATTTATATT
CAATTGAATAATGGATTGGT

Downstream 100 bases:

>100_bases
TGTCGACGTCCGCGGCCCGTCTGATGACCATTCACAAAATGCGCGCCCTGTCGCGCCCGACGCTAACCGCCCTGCTGCTG
CTGTTGGCTGCTTTGGCGCT

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLRITRPGTQPVPAPQERLIGGTSRSFRRRLFGLLIAVGALLIVMLLSLSLGAKSIPFDTVIQALKGQCSGADCTIITNA
RLPRTLVGILAGIALGLSGVLMQTLTRNPLADPGILGVNAGAGFAVVLGITFFGAVDVSQYLWFAFAGAMFAALLVALIG
ALGGSSLNPVRLTLAGVALAAVLEGMTSGISLLNPLVFDQLRFWQAGSLDIQNMQVVRTVALPILLGTLITLWMSKSLNS
LSMGNELATALGTGIVRTQLLGLLAITLLCGGATAAVGPIAFVGLMMPHIARRLGGSELHWMLPWTLVLTPILLLSADLI
GRFLVAGELRVSIVTALIGAPLLIMLVRQRHMFRRQR

Sequences:

>Translated_357_residues
MLRITRPGTQPVPAPQERLIGGTSRSFRRRLFGLLIAVGALLIVMLLSLSLGAKSIPFDTVIQALKGQCSGADCTIITNA
RLPRTLVGILAGIALGLSGVLMQTLTRNPLADPGILGVNAGAGFAVVLGITFFGAVDVSQYLWFAFAGAMFAALLVALIG
ALGGSSLNPVRLTLAGVALAAVLEGMTSGISLLNPLVFDQLRFWQAGSLDIQNMQVVRTVALPILLGTLITLWMSKSLNS
LSMGNELATALGTGIVRTQLLGLLAITLLCGGATAAVGPIAFVGLMMPHIARRLGGSELHWMLPWTLVLTPILLLSADLI
GRFLVAGELRVSIVTALIGAPLLIMLVRQRHMFRRQR
>Mature_357_residues
MLRITRPGTQPVPAPQERLIGGTSRSFRRRLFGLLIAVGALLIVMLLSLSLGAKSIPFDTVIQALKGQCSGADCTIITNA
RLPRTLVGILAGIALGLSGVLMQTLTRNPLADPGILGVNAGAGFAVVLGITFFGAVDVSQYLWFAFAGAMFAALLVALIG
ALGGSSLNPVRLTLAGVALAAVLEGMTSGISLLNPLVFDQLRFWQAGSLDIQNMQVVRTVALPILLGTLITLWMSKSLNS
LSMGNELATALGTGIVRTQLLGLLAITLLCGGATAAVGPIAFVGLMMPHIARRLGGSELHWMLPWTLVLTPILLLSADLI
GRFLVAGELRVSIVTALIGAPLLIMLVRQRHMFRRQR

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=64.3564356435644, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1790740, Length=308, Percent_Identity=33.4415584415584, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790741, Length=319, Percent_Identity=33.5423197492163, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786804, Length=272, Percent_Identity=33.4558823529412, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=33.1010452961672, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37595; Mature: 37595

Theoretical pI: Translated: 12.06; Mature: 12.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRITRPGTQPVPAPQERLIGGTSRSFRRRLFGLLIAVGALLIVMLLSLSLGAKSIPFDT
CCEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VIQALKGQCSGADCTIITNARLPRTLVGILAGIALGLSGVLMQTLTRNPLADPGILGVNA
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GAGFAVVLGITFFGAVDVSQYLWFAFAGAMFAALLVALIGALGGSSLNPVRLTLAGVALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVLEGMTSGISLLNPLVFDQLRFWQAGSLDIQNMQVVRTVALPILLGTLITLWMSKSLNS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LSMGNELATALGTGIVRTQLLGLLAITLLCGGATAAVGPIAFVGLMMPHIARRLGGSELH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
WMLPWTLVLTPILLLSADLIGRFLVAGELRVSIVTALIGAPLLIMLVRQRHMFRRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRITRPGTQPVPAPQERLIGGTSRSFRRRLFGLLIAVGALLIVMLLSLSLGAKSIPFDT
CCEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VIQALKGQCSGADCTIITNARLPRTLVGILAGIALGLSGVLMQTLTRNPLADPGILGVNA
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GAGFAVVLGITFFGAVDVSQYLWFAFAGAMFAALLVALIGALGGSSLNPVRLTLAGVALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVLEGMTSGISLLNPLVFDQLRFWQAGSLDIQNMQVVRTVALPILLGTLITLWMSKSLNS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LSMGNELATALGTGIVRTQLLGLLAITLLCGGATAAVGPIAFVGLMMPHIARRLGGSELH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
WMLPWTLVLTPILLLSADLIGRFLVAGELRVSIVTALIGAPLLIMLVRQRHMFRRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]