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The map label for this gene is idnR [H]

Identifier: 157371526

GI number: 157371526

Start: 3640677

End: 3641660

Strand: Direct

Name: idnR [H]

Synonym: Spro_3289

Alternate gene names: 157371526

Gene position: 3640677-3641660 (Clockwise)

Preceding gene: 157371522

Following gene: 157371532

Centisome position: 66.82

GC content: 57.83

Gene sequence:

>984_bases
ATGAAGAACCAACGCGTCACGCTGCAGGATATTGCACTGCTCGCCGGTGTGACCAAAATGACCGTCAGCCGCTATCTGCG
CACGCCGGACAAGGTGGCTGCCGAAACGGCTGCGAAAATTGCCCAGGTGATGAAAGAAGTTAACTTCACCGACAGCGATG
AGGCGCGATCGTCCCAAAAGCCGCGCATCGGCGTGCTGATCCCCTCCTTCAACAACCAGATCTTTGCCGATCTGCTGGCC
GGCATCGAATCCATCACCCTCGAACACGGCTATCAAACTCTGGTGGTTAACTATGACTACAGCCGGCAGCGGGAAGAGGA
ACAGATTATCCAACTGCTGGCCTACCCCATCGCCGGGTTGATCCTCACCGATTCGGAGCACACCCTGCGGGCGGAAAAAT
ATCTGGCGGCAACCAAAATCCCGGTGGCGCAGGTAATGAGTCTTGAAGGGCCCGAGGGGCGGATCGCCGTGGGTTTTGAT
AACTATCAGGCGGGTTTTGACATGACCGAAGCGCTGCTCGCCAGCGGGAAACGCCAGGTGGTTTACTTTGGTGCCATGTC
CGACGCACGCGACACCAAGCGTTTCCAGGGCTATTGTCGGGCGATGGAAAATCAGGGACTGACGCCACGGCAAATCACGC
CGCATCGGGTCTCGTCGGTCTCGGTCGGTTCTGACATGCTGGCCATGGCCCGCCAGCTCTACCCCAGTCTGGACGGCATT
TTGTGCACCAATGACGATCTGGCGGTTGGCGTGTTGCAGGCGTGTCTGCGGCTCGGACTAAAGGTGCCACAGGACATTGC
GCTGTCAGGTTTTCACGGTCTGGATATTGGCAAGGCCACCACGCCGGGCATCGCCAGCGTGATCACCCCAAGGTTTGATA
TGGGCAAAGTCGCCACAGAGATTTTACTCAAACGCATCAAAGGGGTGCCGTGCATCGAGCGCGTTGACCTGCACTACCGC
ATTTCACTCGGCGGCACCATTTAA

Upstream 100 bases:

>100_bases
AGGGATTTTACACTTTATAACGCCGATTGTTATCGCCAGATCGATTTGTTAACATGACAGAATTCGCAATCTCTCCGCCC
CACGCTGTTAAGGCCCCTAA

Downstream 100 bases:

>100_bases
ATCAGCGGTTAACATGCTCGGTAACAGCGCCAGCTTGTTTGGGTTTCTCATTGCGTGCCGCCAGCCAAAGACCGCTGTTT
TTCATCGCGTAGCCGAACAC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRTPDKVAAETAAKIAQVMKEVNFTDSDEARSSQKPRIGVLIPSFNNQIFADLLA
GIESITLEHGYQTLVVNYDYSRQREEEQIIQLLAYPIAGLILTDSEHTLRAEKYLAATKIPVAQVMSLEGPEGRIAVGFD
NYQAGFDMTEALLASGKRQVVYFGAMSDARDTKRFQGYCRAMENQGLTPRQITPHRVSSVSVGSDMLAMARQLYPSLDGI
LCTNDDLAVGVLQACLRLGLKVPQDIALSGFHGLDIGKATTPGIASVITPRFDMGKVATEILLKRIKGVPCIERVDLHYR
ISLGGTI

Sequences:

>Translated_327_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRTPDKVAAETAAKIAQVMKEVNFTDSDEARSSQKPRIGVLIPSFNNQIFADLLA
GIESITLEHGYQTLVVNYDYSRQREEEQIIQLLAYPIAGLILTDSEHTLRAEKYLAATKIPVAQVMSLEGPEGRIAVGFD
NYQAGFDMTEALLASGKRQVVYFGAMSDARDTKRFQGYCRAMENQGLTPRQITPHRVSSVSVGSDMLAMARQLYPSLDGI
LCTNDDLAVGVLQACLRLGLKVPQDIALSGFHGLDIGKATTPGIASVITPRFDMGKVATEILLKRIKGVPCIERVDLHYR
ISLGGTI
>Mature_327_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRTPDKVAAETAAKIAQVMKEVNFTDSDEARSSQKPRIGVLIPSFNNQIFADLLA
GIESITLEHGYQTLVVNYDYSRQREEEQIIQLLAYPIAGLILTDSEHTLRAEKYLAATKIPVAQVMSLEGPEGRIAVGFD
NYQAGFDMTEALLASGKRQVVYFGAMSDARDTKRFQGYCRAMENQGLTPRQITPHRVSSVSVGSDMLAMARQLYPSLDGI
LCTNDDLAVGVLQACLRLGLKVPQDIALSGFHGLDIGKATTPGIASVITPRFDMGKVATEILLKRIKGVPCIERVDLHYR
ISLGGTI

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=48.1927710843374, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=45.3172205438066, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1790369, Length=315, Percent_Identity=27.3015873015873, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=29.126213592233, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=26.2839879154079, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=23.5690235690236, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788474, Length=315, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789202, Length=312, Percent_Identity=24.3589743589744, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=22.8228228228228, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787906, Length=263, Percent_Identity=22.4334600760456, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786540, Length=314, Percent_Identity=24.8407643312102, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35835; Mature: 35835

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQRVTLQDIALLAGVTKMTVSRYLRTPDKVAAETAAKIAQVMKEVNFTDSDEARSSQK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
PRIGVLIPSFNNQIFADLLAGIESITLEHGYQTLVVNYDYSRQREEEQIIQLLAYPIAGL
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCE
ILTDSEHTLRAEKYLAATKIPVAQVMSLEGPEGRIAVGFDNYQAGFDMTEALLASGKRQV
EEECCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEE
VYFGAMSDARDTKRFQGYCRAMENQGLTPRQITPHRVSSVSVGSDMLAMARQLYPSLDGI
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
LCTNDDLAVGVLQACLRLGLKVPQDIALSGFHGLDIGKATTPGIASVITPRFDMGKVATE
EECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
ILLKRIKGVPCIERVDLHYRISLGGTI
HHHHHHCCCCCCEECCEEEEEECCCCC
>Mature Secondary Structure
MKNQRVTLQDIALLAGVTKMTVSRYLRTPDKVAAETAAKIAQVMKEVNFTDSDEARSSQK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
PRIGVLIPSFNNQIFADLLAGIESITLEHGYQTLVVNYDYSRQREEEQIIQLLAYPIAGL
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCE
ILTDSEHTLRAEKYLAATKIPVAQVMSLEGPEGRIAVGFDNYQAGFDMTEALLASGKRQV
EEECCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEE
VYFGAMSDARDTKRFQGYCRAMENQGLTPRQITPHRVSSVSVGSDMLAMARQLYPSLDGI
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
LCTNDDLAVGVLQACLRLGLKVPQDIALSGFHGLDIGKATTPGIASVITPRFDMGKVATE
EECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
ILLKRIKGVPCIERVDLHYRISLGGTI
HHHHHHCCCCCCEECCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]