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The map label for this gene is yafC [H]

Identifier: 157371370

GI number: 157371370

Start: 3447499

End: 3448428

Strand: Direct

Name: yafC [H]

Synonym: Spro_3131

Alternate gene names: 157371370

Gene position: 3447499-3448428 (Clockwise)

Preceding gene: 157371367

Following gene: 157371371

Centisome position: 63.27

GC content: 57.2

Gene sequence:

>930_bases
ATGTCTACCGGAATTACAGCAGAATCCCTGCGGGGAATTACTAACTTTGTCATTACTGCGAAATCGAGCAGCTTCACTGC
GGCCGCGGAGCAACTGGGCATTACCAAATCGGCAGTAGGTAAAAGTGTGGCCCGGCTTGAGGAGAGGTTGGGAACGCGTC
TTTTTCACCGCTCAACGCGTAAACTGAGCCTGACGAGTGATGGGGAGGCTTACCTGACCAGTTGCCTCTCGGCGCTTGAA
ATTCTCGACTCTGCCGAGAACACGCTCAGCAGACGGCAGGAAAATCCCACCGGGACGGTCCGTATTGATATGCCGGCGTC
TTTCGGACGGAATCTGATGATGCCGGTATTGATCGAGATGATGACCCGCTACCCGGCCCTGCGGTTGGCGCTAACTTTCA
ATGACCGTCTTATTGACCCGGTGGAGGAAGGCGTTGACCTGGTGCTGCGGCTGGGAGAGCTACAGAGCACCGATGAGCTG
ATCGCCCGTCGCCTGAGCCGGCAGCGGCTTATATTGTGCGCCTCTCCGGCCTATCTTGAACGGCACGGCCTGCCTGCCGA
TATAGAGGATTTGAAAAGCCACTACTGCGTTATGGGCTACCGCCGGGGCGCCCCCCTCGCCTGGCGGCTGCGAAAGGCCG
GGGAGCGTGAAGTGAAATTCATATCCGCCACAGCACATCAGATAAGCGACGGAGATGCCATGATTCAGGCCTGTCTGGCT
GGCGTGGGGATAGCTCAGTTTCCTGAGTCGATGGTTAACAGCCATATCGCCGCAGGCAGCCTGATCTCTCTGATGGCAGA
CCATGCCCCCATCCCGGTTGAGCTGAACGTCATCTGGCCCCGAACAAGGCACCTCATACCCAGAGTTCGCCTTATCGTTG
ACGAACTGCTGAAAAAGGCCGGAGAAGGCTATTTCGGCACGCTTAGGTAG

Upstream 100 bases:

>100_bases
CTGATATCAGGTTGCCGGTGCTTTACTTACTGATAGGGATAAGCCTGGTATAGAATTACACATCGATAAACGCACAATGA
ATCGTCATTGAGTAAACTTT

Downstream 100 bases:

>100_bases
AGATTTTGTCGTCACTGAGGCGATATCTGGGCTGTTTATCGCCTTTTAGCAAACTTATATCCTTATCGTCCCGCTGCTTT
TGTTGCCTTACGGGCTGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSTGITAESLRGITNFVITAKSSSFTAAAEQLGITKSAVGKSVARLEERLGTRLFHRSTRKLSLTSDGEAYLTSCLSALE
ILDSAENTLSRRQENPTGTVRIDMPASFGRNLMMPVLIEMMTRYPALRLALTFNDRLIDPVEEGVDLVLRLGELQSTDEL
IARRLSRQRLILCASPAYLERHGLPADIEDLKSHYCVMGYRRGAPLAWRLRKAGEREVKFISATAHQISDGDAMIQACLA
GVGIAQFPESMVNSHIAAGSLISLMADHAPIPVELNVIWPRTRHLIPRVRLIVDELLKKAGEGYFGTLR

Sequences:

>Translated_309_residues
MSTGITAESLRGITNFVITAKSSSFTAAAEQLGITKSAVGKSVARLEERLGTRLFHRSTRKLSLTSDGEAYLTSCLSALE
ILDSAENTLSRRQENPTGTVRIDMPASFGRNLMMPVLIEMMTRYPALRLALTFNDRLIDPVEEGVDLVLRLGELQSTDEL
IARRLSRQRLILCASPAYLERHGLPADIEDLKSHYCVMGYRRGAPLAWRLRKAGEREVKFISATAHQISDGDAMIQACLA
GVGIAQFPESMVNSHIAAGSLISLMADHAPIPVELNVIWPRTRHLIPRVRLIVDELLKKAGEGYFGTLR
>Mature_308_residues
STGITAESLRGITNFVITAKSSSFTAAAEQLGITKSAVGKSVARLEERLGTRLFHRSTRKLSLTSDGEAYLTSCLSALEI
LDSAENTLSRRQENPTGTVRIDMPASFGRNLMMPVLIEMMTRYPALRLALTFNDRLIDPVEEGVDLVLRLGELQSTDELI
ARRLSRQRLILCASPAYLERHGLPADIEDLKSHYCVMGYRRGAPLAWRLRKAGEREVKFISATAHQISDGDAMIQACLAG
VGIAQFPESMVNSHIAAGSLISLMADHAPIPVELNVIWPRTRHLIPRVRLIVDELLKKAGEGYFGTLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=34.8993288590604, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=30.6122448979592, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=32.6460481099656, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=27.8745644599303, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=30.0675675675676, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789440, Length=301, Percent_Identity=30.2325581395349, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=27.6094276094276, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788706, Length=270, Percent_Identity=26.2962962962963, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789173, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790011, Length=290, Percent_Identity=24.8275862068966, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=302, Percent_Identity=24.5033112582781, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=31.404958677686, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790783, Length=276, Percent_Identity=25.3623188405797, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=269, Percent_Identity=24.907063197026, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34069; Mature: 33938

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGITAESLRGITNFVITAKSSSFTAAAEQLGITKSAVGKSVARLEERLGTRLFHRSTR
CCCCCCHHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KLSLTSDGEAYLTSCLSALEILDSAENTLSRRQENPTGTVRIDMPASFGRNLMMPVLIEM
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCHHHHHHHHH
MTRYPALRLALTFNDRLIDPVEEGVDLVLRLGELQSTDELIARRLSRQRLILCASPAYLE
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHH
RHGLPADIEDLKSHYCVMGYRRGAPLAWRLRKAGEREVKFISATAHQISDGDAMIQACLA
HCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHCCCHHHEEEHHHHHHCCCHHHHHHHHHH
GVGIAQFPESMVNSHIAAGSLISLMADHAPIPVELNVIWPRTRHLIPRVRLIVDELLKKA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
GEGYFGTLR
CCCCCCCCC
>Mature Secondary Structure 
STGITAESLRGITNFVITAKSSSFTAAAEQLGITKSAVGKSVARLEERLGTRLFHRSTR
CCCCCHHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KLSLTSDGEAYLTSCLSALEILDSAENTLSRRQENPTGTVRIDMPASFGRNLMMPVLIEM
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCHHHHHHHHH
MTRYPALRLALTFNDRLIDPVEEGVDLVLRLGELQSTDELIARRLSRQRLILCASPAYLE
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHH
RHGLPADIEDLKSHYCVMGYRRGAPLAWRLRKAGEREVKFISATAHQISDGDAMIQACLA
HCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHCCCHHHEEEHHHHHHCCCHHHHHHHHHH
GVGIAQFPESMVNSHIAAGSLISLMADHAPIPVELNVIWPRTRHLIPRVRLIVDELLKKA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
GEGYFGTLR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]