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The map label for this gene is 157371364

Identifier: 157371364

GI number: 157371364

Start: 3439455

End: 3440390

Strand: Direct

Name: 157371364

Synonym: Spro_3125

Alternate gene names: NA

Gene position: 3439455-3440390 (Clockwise)

Preceding gene: 157371363

Following gene: 157371365

Centisome position: 63.12

GC content: 55.98

Gene sequence:

>936_bases
ATGATTAATAAAACCCTCTGCGGACTGATGCTCTGCACCACGCTGACCGGGCAAGCTACCGCCGCAGAAAAACTGACGCT
GGTGCTCGACTGGTATATCAACCCCGATCACGCGCCGATTATGGTGGCCGAGCAGATCGGTGCCTTCAAGGCCGCAGGCC
TGGACGTCAAGATTGTGCCGCCTTCCGATCCGGCGCTACCACCACGGTTGGTGGCGGCAAAACAGGCCGATCTGGCCATC
ACCTATCAGCCGCAGCTGCATTTCTTTGCCGATCAGGGCCTGCCGCTGGTGCGCGTGGGTACCCTGATTAATTCACCGCT
CAATACCGTAATTACGCTGGATAAAAGCATTACCACCCCGGCAGGGCTGAAGGGCAAAAAAATCGGTTACTCGGTCAGCG
GCATCGAACAGGCCACGCTGGCAACCATGTTCAAGCATGAACACCTCAACCCTGACGACGGTAAGTTGATTAACGTTAAT
TTCCAACTGACCAGCGCCCTGCTGGCAGGTCAGGTTGATGCGGTGATTGGCGGATATCGTAATAACGAGGCGCTGGAGCT
AAAGTTGCAGGGCAAGGATCCGGTGGTGTTTAACGTGGAAGACTACGGCGTGCCAGCCTACGACGAACTGATTATCGTCG
CCAATCGCGACGCGGTGGGCGAGCCGAAAATCAAAAAATTCCTCACGGCGCTGAAAAAAGGCAACGATTACCTGCAGGCT
CACCCACAGGAAAGCTGGCTGGCGTTCGCCAAGGCCCACCCGGAACTCAATACCGAGTTGAACAAACAGGCCTGGCAGGC
CAGCCTGCCGCTGTTCGCCCGCGATCCGGCCAGGCTGGATAAAGCGCGCTATCAGGCCTATGAACAGTTCCTATTCGACA
ATAAGCTGATCAAGAAAATCACCCCGGTAGAGCAGTATGCGGTGGAGTTGCCTTAA

Upstream 100 bases:

>100_bases
CTGGTGCTGATGACCGTCCTGCTTTGGGTGACGGTGGACGCGCTGTTGCTGCGCCTGATCGACTGGGCGCCGGAAAATGA
CTGATAACAAGGGATCCACA

Downstream 100 bases:

>100_bases
AGGGCGCGTTGGTCTGTTTGACCCTCTCCCGAAGGAGAGGGCCTATTTTGCGCTCTGCTGCTCTCAGACGTGATTAGTGT
CACAGTAATGTCACAAAAAA

Product: NMT1/THI5-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MINKTLCGLMLCTTLTGQATAAEKLTLVLDWYINPDHAPIMVAEQIGAFKAAGLDVKIVPPSDPALPPRLVAAKQADLAI
TYQPQLHFFADQGLPLVRVGTLINSPLNTVITLDKSITTPAGLKGKKIGYSVSGIEQATLATMFKHEHLNPDDGKLINVN
FQLTSALLAGQVDAVIGGYRNNEALELKLQGKDPVVFNVEDYGVPAYDELIIVANRDAVGEPKIKKFLTALKKGNDYLQA
HPQESWLAFAKAHPELNTELNKQAWQASLPLFARDPARLDKARYQAYEQFLFDNKLIKKITPVEQYAVELP

Sequences:

>Translated_311_residues
MINKTLCGLMLCTTLTGQATAAEKLTLVLDWYINPDHAPIMVAEQIGAFKAAGLDVKIVPPSDPALPPRLVAAKQADLAI
TYQPQLHFFADQGLPLVRVGTLINSPLNTVITLDKSITTPAGLKGKKIGYSVSGIEQATLATMFKHEHLNPDDGKLINVN
FQLTSALLAGQVDAVIGGYRNNEALELKLQGKDPVVFNVEDYGVPAYDELIIVANRDAVGEPKIKKFLTALKKGNDYLQA
HPQESWLAFAKAHPELNTELNKQAWQASLPLFARDPARLDKARYQAYEQFLFDNKLIKKITPVEQYAVELP
>Mature_311_residues
MINKTLCGLMLCTTLTGQATAAEKLTLVLDWYINPDHAPIMVAEQIGAFKAAGLDVKIVPPSDPALPPRLVAAKQADLAI
TYQPQLHFFADQGLPLVRVGTLINSPLNTVITLDKSITTPAGLKGKKIGYSVSGIEQATLATMFKHEHLNPDDGKLINVN
FQLTSALLAGQVDAVIGGYRNNEALELKLQGKDPVVFNVEDYGVPAYDELIIVANRDAVGEPKIKKFLTALKKGNDYLQA
HPQESWLAFAKAHPELNTELNKQAWQASLPLFARDPARLDKARYQAYEQFLFDNKLIKKITPVEQYAVELP

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319957, Length=269, Percent_Identity=27.5092936802974, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321050, Length=269, Percent_Identity=27.5092936802974, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323997, Length=269, Percent_Identity=27.5092936802974, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322616, Length=269, Percent_Identity=27.1375464684015, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 34137; Mature: 34137

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKTLCGLMLCTTLTGQATAAEKLTLVLDWYINPDHAPIMVAEQIGAFKAAGLDVKIVP
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEEEEHHHCCEEECCCEEEEEC
PSDPALPPRLVAAKQADLAITYQPQLHFFADQGLPLVRVGTLINSPLNTVITLDKSITTP
CCCCCCCCHHEEECCCCEEEEECCCEEEEECCCCCEEEEHHHHCCCCCEEEEECCCCCCC
AGLKGKKIGYSVSGIEQATLATMFKHEHLNPDDGKLINVNFQLTSALLAGQVDAVIGGYR
CCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHCCCC
NNEALELKLQGKDPVVFNVEDYGVPAYDELIIVANRDAVGEPKIKKFLTALKKGNDYLQA
CCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEC
HPQESWLAFAKAHPELNTELNKQAWQASLPLFARDPARLDKARYQAYEQFLFDNKLIKKI
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHC
TPVEQYAVELP
CCHHHHEECCC
>Mature Secondary Structure
MINKTLCGLMLCTTLTGQATAAEKLTLVLDWYINPDHAPIMVAEQIGAFKAAGLDVKIVP
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEEEEHHHCCEEECCCEEEEEC
PSDPALPPRLVAAKQADLAITYQPQLHFFADQGLPLVRVGTLINSPLNTVITLDKSITTP
CCCCCCCCHHEEECCCCEEEEECCCEEEEECCCCCEEEEHHHHCCCCCEEEEECCCCCCC
AGLKGKKIGYSVSGIEQATLATMFKHEHLNPDDGKLINVNFQLTSALLAGQVDAVIGGYR
CCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHCCCC
NNEALELKLQGKDPVVFNVEDYGVPAYDELIIVANRDAVGEPKIKKFLTALKKGNDYLQA
CCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEC
HPQESWLAFAKAHPELNTELNKQAWQASLPLFARDPARLDKARYQAYEQFLFDNKLIKKI
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHC
TPVEQYAVELP
CCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]