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The map label for this gene is glxA [H]

Identifier: 157371348

GI number: 157371348

Start: 3420676

End: 3421638

Strand: Direct

Name: glxA [H]

Synonym: Spro_3109

Alternate gene names: 157371348

Gene position: 3420676-3421638 (Clockwise)

Preceding gene: 157371344

Following gene: 157371349

Centisome position: 62.78

GC content: 57.94

Gene sequence:

>963_bases
ATGGCGCCACTTAAAGTGGGTATCGTGGTTTTTAACAACATCATCCCGTTTCACCTTTCGGTGCCCTGTGCAGTGTTTGA
GAAGGCACTGAACAGCAACGGGGAACCGGCCTATCAGCTGTTGATTTGCGCCACCGAACCCGGCCCATTAAAGACCAACG
CTGGTTTCTCGATAGTTGCCGATCATGGATTAGCGGCGTTGGCGCAAGCCGATATGGTGATAGTGCCCAGCTGGTGCAAT
CCCGAAGTCCCGCCATCACCACAACTTATCGACGCCCTGCTAGACGCCCATGCGCGTGGCGCTACCCTGGTCGGCCTGTG
TGTCGGAAGCTTCGTTCTGGCGGCGGCCGGCTTACTCAACGGCCGTCCGGCAACCACCCATTGGCAATGGATGGCGGATT
TTCTGCGACGATATCCCCAGGTGTCGATAGACCAGAATGTGCTGTACGTGGATGACGGTGATATTGTCACTTCCGCTGGC
ACCGCCGCCAGCATCGACTGCTGCCTGCACCTGGTACGCAAGCACTGTGGTGCGGAGAGCGCCAACGCGGTGGCCAGGCA
GTTGGTGGTGCCGCCACACCGTCAGGGCGGCCAGGCACAGTTTATCGAGCAACCGGTGTATAACACTGTGGGCGGTGACC
GTTTTATGCAAACGCTGAATTGGGCAACGGAAAATCTGCAGCAACCGCTGACGCTGGATGCACTGGCGGACAAAGCCTGC
ATGAGTCGCCGCAGCTTTACCCGGCGCTTTCAGCAAACTACCGGCACCAGCGTCATGCAGTGGTTGCTGAATCAGCGGCT
GGCGATGGCGCAGCGCTTTCTGGAAAAAACCGACCAGCCCGTCGAGCGCATTGCGCAGGCCGCAGGTTTCGCCACTGCGT
TGTCAATGCGCAGGCATTTTCAGCGGCAGTTCAAGACGTCGCCGTCTTTATATCGCAAGGAGTTTCGCGTTACGGAAAAA
TAA

Upstream 100 bases:

>100_bases
CTGCAGGTTGCAGTGATATGGCAACAGGTAGTCTAATAACCAAAAGCGATATCATCGGGCCAAATCGTCCACATAGGGTT
AATGATAAAAAGGAAGCAGT

Downstream 100 bases:

>100_bases
GCCGGTCATTCTTACTGGTAGCGGTGGAATTCGGTGATGCTGTGAAGGGCTATCTGTGACGGGGATCGTTGAAAGAATTT
TATCTAAGTGATTGAATAAT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAPLKVGIVVFNNIIPFHLSVPCAVFEKALNSNGEPAYQLLICATEPGPLKTNAGFSIVADHGLAALAQADMVIVPSWCN
PEVPPSPQLIDALLDAHARGATLVGLCVGSFVLAAAGLLNGRPATTHWQWMADFLRRYPQVSIDQNVLYVDDGDIVTSAG
TAASIDCCLHLVRKHCGAESANAVARQLVVPPHRQGGQAQFIEQPVYNTVGGDRFMQTLNWATENLQQPLTLDALADKAC
MSRRSFTRRFQQTTGTSVMQWLLNQRLAMAQRFLEKTDQPVERIAQAAGFATALSMRRHFQRQFKTSPSLYRKEFRVTEK

Sequences:

>Translated_320_residues
MAPLKVGIVVFNNIIPFHLSVPCAVFEKALNSNGEPAYQLLICATEPGPLKTNAGFSIVADHGLAALAQADMVIVPSWCN
PEVPPSPQLIDALLDAHARGATLVGLCVGSFVLAAAGLLNGRPATTHWQWMADFLRRYPQVSIDQNVLYVDDGDIVTSAG
TAASIDCCLHLVRKHCGAESANAVARQLVVPPHRQGGQAQFIEQPVYNTVGGDRFMQTLNWATENLQQPLTLDALADKAC
MSRRSFTRRFQQTTGTSVMQWLLNQRLAMAQRFLEKTDQPVERIAQAAGFATALSMRRHFQRQFKTSPSLYRKEFRVTEK
>Mature_319_residues
APLKVGIVVFNNIIPFHLSVPCAVFEKALNSNGEPAYQLLICATEPGPLKTNAGFSIVADHGLAALAQADMVIVPSWCNP
EVPPSPQLIDALLDAHARGATLVGLCVGSFVLAAAGLLNGRPATTHWQWMADFLRRYPQVSIDQNVLYVDDGDIVTSAGT
AASIDCCLHLVRKHCGAESANAVARQLVVPPHRQGGQAQFIEQPVYNTVGGDRFMQTLNWATENLQQPLTLDALADKACM
SRRSFTRRFQQTTGTSVMQWLLNQRLAMAQRFLEKTDQPVERIAQAAGFATALSMRRHFQRQFKTSPSLYRKEFRVTEK

Specific function: May Be A Transcriptional Activator Of Genes Involved In The Multiple Antibiotic Resistance (Mar) Phenotype. It Can Also Activate Genes Such As Soda, Zwf And Micf. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35157; Mature: 35026

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLKVGIVVFNNIIPFHLSVPCAVFEKALNSNGEPAYQLLICATEPGPLKTNAGFSIVA
CCCCEEHHHHHCCCCCEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEE
DHGLAALAQADMVIVPSWCNPEVPPSPQLIDALLDAHARGATLVGLCVGSFVLAAAGLLN
CCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
GRPATTHWQWMADFLRRYPQVSIDQNVLYVDDGDIVTSAGTAASIDCCLHLVRKHCGAES
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCH
ANAVARQLVVPPHRQGGQAQFIEQPVYNTVGGDRFMQTLNWATENLQQPLTLDALADKAC
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MSRRSFTRRFQQTTGTSVMQWLLNQRLAMAQRFLEKTDQPVERIAQAAGFATALSMRRHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QRQFKTSPSLYRKEFRVTEK
HHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
APLKVGIVVFNNIIPFHLSVPCAVFEKALNSNGEPAYQLLICATEPGPLKTNAGFSIVA
CCCEEHHHHHCCCCCEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEE
DHGLAALAQADMVIVPSWCNPEVPPSPQLIDALLDAHARGATLVGLCVGSFVLAAAGLLN
CCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
GRPATTHWQWMADFLRRYPQVSIDQNVLYVDDGDIVTSAGTAASIDCCLHLVRKHCGAES
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCH
ANAVARQLVVPPHRQGGQAQFIEQPVYNTVGGDRFMQTLNWATENLQQPLTLDALADKAC
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MSRRSFTRRFQQTTGTSVMQWLLNQRLAMAQRFLEKTDQPVERIAQAAGFATALSMRRHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QRQFKTSPSLYRKEFRVTEK
HHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]