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The map label for this gene is ykvY [H]

Identifier: 157371271

GI number: 157371271

Start: 3335216

End: 3336433

Strand: Direct

Name: ykvY [H]

Synonym: Spro_3031

Alternate gene names: 157371271

Gene position: 3335216-3336433 (Clockwise)

Preceding gene: 157371260

Following gene: 157371273

Centisome position: 61.21

GC content: 57.39

Gene sequence:

>1218_bases
ATGGCTACAGGCATTGGCGGTTGCACGGCGCAACAGGCCCTGGAACAGTTGCAACCGTTGACGGACAATCCGCCTGAAAT
CGCCGGCGATGAGTATCGGCAACGCATTCAGCATGCGCAGCGCCTGATGCGCGAAAACGGTATCGACGCCTGCTATGTCA
ACGCCGGCAGTAATCTGCGCTATTTTACCGGTACTCAATGGTCGGCGAGTGAACGCATGGTCGGTGCGGTGATCCCGACC
GAAGGCGAAATCGCCTATATTGCCCCCTGGTTTGAAACTGGCACCTTCAAAGACGCACAGGTGATAGAAGCAGAAATTTT
TAGCTGGCATGAGGAAGAAGATCCCTACCGGTTGTTCTTCACCGTACTGGCCTCTCGCGGGCTAACGGGCGCACGCCAGG
TGGCAATTTGCGAAACGGCTTCGGTCACCCTGTTCCTCGGCCTGCAACAATATGCCGGCGATATCAGGCTGATCAGTGCC
CAGCCGATCACCGGCCATTGCCGCAGCCGTAAATCGGCGACGGAAATCGTACTGATGCAAACCGCCAATAATATTACTCT
GCGGGTGCAACAGGCTGCGGCCAGCATATTGCGCCCTGGCATCACCGCCAGCGAACTGATCGACTTCGTCGATAAAGCCC
ACCGTAAAATGGGCACCAGCGGCTCGTACTTCTGTATTGCACTGTTCGGATCCGATAGCGCGTTCCCCCATGGCGTGAAA
CAACCCAACCCGCTGCAAAACAACGATATCGTGCTGCTCGATACCGGCTGCCGCTATAAGGGTTACCTGTCCGATATCAC
CCGTACCTATGTGTACGGCGAAGCCAACGAACGGCAGCGTTTCGCCTGGCAGGCGGAGCATGAGGCGCAGGCCGCCGCTT
TTGCCGTTATCGCGCCCGGTGTGCCCTGCCATAAAGTGGATGACGCGGCACGCGATGTGCTGGTTTCTTATGGATTTGGG
CCGGACTATCAGCTGCCGGGCCTGCCGCATCGCACCGGGCACGGTATCGGGCTGGATATTCATGAAGCCCCGTATCTGAT
CCGCAAACAGCAGCAACCGCTCGATGTCGGCATGTGCGCCAGCATCGAACCCATGCTGTGCCTGCCGGGTGAGTTTGGCA
TCCGCCTTGAAGATCATTTTTACGTCACCCACGAAGGTGCACGCTGGTTTACCCCGCCGGCAAAATCCATTGATAACCCA
TTTGATTTAGCGGGCTGA

Upstream 100 bases:

>100_bases
TCTAATAAAGCCAAGTTTTGTTGCTGTGGTTTACTTATGATGAAGGTTTAGTGCGCAGGAGCATCGGCCCTGACATTTGA
CACTACGCGAGGAGAGAAGC

Downstream 100 bases:

>100_bases
TAATCCCCCGGGCGGCGATGCCGCTCGGGTTTAAATATAAATATTAATATCGACCATGTTTAATAAAACCATTTAATTAT
AAAACTTAGTGAAACCACTA

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MATGIGGCTAQQALEQLQPLTDNPPEIAGDEYRQRIQHAQRLMRENGIDACYVNAGSNLRYFTGTQWSASERMVGAVIPT
EGEIAYIAPWFETGTFKDAQVIEAEIFSWHEEEDPYRLFFTVLASRGLTGARQVAICETASVTLFLGLQQYAGDIRLISA
QPITGHCRSRKSATEIVLMQTANNITLRVQQAAASILRPGITASELIDFVDKAHRKMGTSGSYFCIALFGSDSAFPHGVK
QPNPLQNNDIVLLDTGCRYKGYLSDITRTYVYGEANERQRFAWQAEHEAQAAAFAVIAPGVPCHKVDDAARDVLVSYGFG
PDYQLPGLPHRTGHGIGLDIHEAPYLIRKQQQPLDVGMCASIEPMLCLPGEFGIRLEDHFYVTHEGARWFTPPAKSIDNP
FDLAG

Sequences:

>Translated_405_residues
MATGIGGCTAQQALEQLQPLTDNPPEIAGDEYRQRIQHAQRLMRENGIDACYVNAGSNLRYFTGTQWSASERMVGAVIPT
EGEIAYIAPWFETGTFKDAQVIEAEIFSWHEEEDPYRLFFTVLASRGLTGARQVAICETASVTLFLGLQQYAGDIRLISA
QPITGHCRSRKSATEIVLMQTANNITLRVQQAAASILRPGITASELIDFVDKAHRKMGTSGSYFCIALFGSDSAFPHGVK
QPNPLQNNDIVLLDTGCRYKGYLSDITRTYVYGEANERQRFAWQAEHEAQAAAFAVIAPGVPCHKVDDAARDVLVSYGFG
PDYQLPGLPHRTGHGIGLDIHEAPYLIRKQQQPLDVGMCASIEPMLCLPGEFGIRLEDHFYVTHEGARWFTPPAKSIDNP
FDLAG
>Mature_404_residues
ATGIGGCTAQQALEQLQPLTDNPPEIAGDEYRQRIQHAQRLMRENGIDACYVNAGSNLRYFTGTQWSASERMVGAVIPTE
GEIAYIAPWFETGTFKDAQVIEAEIFSWHEEEDPYRLFFTVLASRGLTGARQVAICETASVTLFLGLQQYAGDIRLISAQ
PITGHCRSRKSATEIVLMQTANNITLRVQQAAASILRPGITASELIDFVDKAHRKMGTSGSYFCIALFGSDSAFPHGVKQ
PNPLQNNDIVLLDTGCRYKGYLSDITRTYVYGEANERQRFAWQAEHEAQAAAFAVIAPGVPCHKVDDAARDVLVSYGFGP
DYQLPGLPHRTGHGIGLDIHEAPYLIRKQQQPLDVGMCASIEPMLCLPGEFGIRLEDHFYVTHEGARWFTPPAKSIDNPF
DLAG

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=186, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=250, Percent_Identity=33.2, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789275, Length=259, Percent_Identity=26.2548262548263, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19920384, Length=247, Percent_Identity=28.3400809716599, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357079, Length=258, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 44642; Mature: 44511

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGIGGCTAQQALEQLQPLTDNPPEIAGDEYRQRIQHAQRLMRENGIDACYVNAGSNLR
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
YFTGTQWSASERMVGAVIPTEGEIAYIAPWFETGTFKDAQVIEAEIFSWHEEEDPYRLFF
EEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
TVLASRGLTGARQVAICETASVTLFLGLQQYAGDIRLISAQPITGHCRSRKSATEIVLMQ
HHHHHCCCCCCCEEEEEECCCEEEEEEHHHHCCCEEEEECCCCCCHHHCCCCCCEEEEEE
TANNITLRVQQAAASILRPGITASELIDFVDKAHRKMGTSGSYFCIALFGSDSAFPHGVK
ECCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
QPNPLQNNDIVLLDTGCRYKGYLSDITRTYVYGEANERQRFAWQAEHEAQAAAFAVIAPG
CCCCCCCCCEEEEECCCCCCHHHHHHHHEEEECCCCCCHHEEECCCHHHHHEEEEEECCC
VPCHKVDDAARDVLVSYGFGPDYQLPGLPHRTGHGIGLDIHEAPYLIRKQQQPLDVGMCA
CCCCHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCC
SIEPMLCLPGEFGIRLEDHFYVTHEGARWFTPPAKSIDNPFDLAG
CCCCEEECCCCCCCEEECEEEEEECCCEEECCCHHHCCCCCCCCC
>Mature Secondary Structure 
ATGIGGCTAQQALEQLQPLTDNPPEIAGDEYRQRIQHAQRLMRENGIDACYVNAGSNLR
CCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
YFTGTQWSASERMVGAVIPTEGEIAYIAPWFETGTFKDAQVIEAEIFSWHEEEDPYRLFF
EEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
TVLASRGLTGARQVAICETASVTLFLGLQQYAGDIRLISAQPITGHCRSRKSATEIVLMQ
HHHHHCCCCCCCEEEEEECCCEEEEEEHHHHCCCEEEEECCCCCCHHHCCCCCCEEEEEE
TANNITLRVQQAAASILRPGITASELIDFVDKAHRKMGTSGSYFCIALFGSDSAFPHGVK
ECCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
QPNPLQNNDIVLLDTGCRYKGYLSDITRTYVYGEANERQRFAWQAEHEAQAAAFAVIAPG
CCCCCCCCCEEEEECCCCCCHHHHHHHHEEEECCCCCCHHEEECCCHHHHHEEEEEECCC
VPCHKVDDAARDVLVSYGFGPDYQLPGLPHRTGHGIGLDIHEAPYLIRKQQQPLDVGMCA
CCCCHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCC
SIEPMLCLPGEFGIRLEDHFYVTHEGARWFTPPAKSIDNPFDLAG
CCCCEEECCCCCCCEEECEEEEEECCCEEECCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]