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The map label for this gene is astB

Identifier: 157371081

GI number: 157371081

Start: 3116996

End: 3118336

Strand: Reverse

Name: astB

Synonym: Spro_2841

Alternate gene names: 157371081

Gene position: 3118336-3116996 (Counterclockwise)

Preceding gene: 157371082

Following gene: 157371080

Centisome position: 57.23

GC content: 58.17

Gene sequence:

>1341_bases
ATGTCAGGATATGAAGTCAATTTCGATGGTCTGGTGGGCCTGACGCATCACTACGCCGGATTGTCATTTGGTAATGAGGC
TTCGACCCAGCACCAAAATAGCGTGTCGAACCCGAAACTGGCGGCCAAGCAAGGCTTGCTGAAGATGAAGGCGTTGGCCG
ATCTCGGTTTCCAGCAGGGGGTTTTACCTCCGCAGGAACGCCCGCATGTGCCGATGTTACGTAAACTGGGCTTCAGCGGC
AGCGATGAAAGCGTGTTGGCGCAGGCGATGCAGCAATCCCCGCGCCTGCTGTCCGCGCTCAGTTCGGCTTCCTGCATGTG
GACCGCCAATGCGGCCACGGTATCGCCTTCCGCGGACAGTGCTGATGGCAAGGTGCATTTTACCGCCGCCAATCTGAACA
ATAAATTCCATCGTGCGATTGAGGCTGAAACCACCTCTGGCGTACTGCGAGCGATGTTTAACGATCCCCGCCATTTCGCC
CATCATGAGGCTTTGCCGCAGGTGGCGCTGTTTGGTGACGAAGGCGCGGCGAACCACAACCGCCTGGGTGGCGACTACGG
CAAGCGCAGCGTGCAGATGTTTGTTTACGGCCGTCAGGAGTTTGGTGGCGAAATTGCCCCAACGCGTTATCCGGCGCGCC
AGACGCGTGAAGCCGGGGAGGCCATTGCCCGTCTGCACCAGTTGGATGAGCAGCACACGGTGTTTGTGCAGCAGAATCCG
GAGGTGATCGATCAGGGCGTGTTCCATAACGACGTGATTGCCGTCAGCAACCAGAACGTGCTGTTCCATCATCAGCAGGC
TTTTTATCGGCAGCAACAGGCGCTGGATGAAGTGCGCCGCAAGATGGCGACGCTGGACAGCGAACTGGTGGCGATTGAGG
TGCCGACGACGAGGGTTTCCGTGGCGGATGCGGTGGCAACCTACCTGTTTAACAGCCAGATCCTGACCAAGCCAAACGGC
AAGATGATGATCGTGGTACCCGAAGAGTCGCGCCAGCACAGCGGCGTCTGGAGTTACCTGAGCGAGATGGTGGCCAGCGG
TGGGCCTATTGACGAAATCAAGGTATTCGATCTGCGTGAGAGCATGCGCAACGGTGGCGGGCCTGCCTGTTTGCGGCTGC
GTGTGGCACTGAATGAGCAGGAGCTGCGGGCGGTGAATCCGCGTGTGATGATGAACGATAGCCTGTTCATCACGCTCAAT
GAATGGGTCGATCGCTATTACCGCGATCGCCTGACGCAAAATGACCTGGCCGACCCGCAACTGTTGCGTGAAGGGCGTGA
AGCGCTGGACTCCCTGACAACCATCCTCGGGTTGGGTTCGGTTTATCCTTTCCAACAATAG

Upstream 100 bases:

>100_bases
GACTGTCATTTAATTAAGTTTTAGCCGCCGCTTTTCAAGCCACAGCGTTGTTACTGTAGGGGCGCAGCATGCAGCGCCCC
TACAAGATCAGGAGAACAGC

Downstream 100 bases:

>100_bases
ACGGAGCCACCATGTTTGATTTGTTGGCCCTGACGCTGGCGGGGCAGGTTCCCGCTGAGCAACAGGGCGAAAATGCGAAT
TTGCACTGGCGTTGGCTGAC

Product: succinylarginine dihydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQGVLPPQERPHVPMLRKLGFSG
SDESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADSADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFA
HHEALPQVALFGDEGAANHNRLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNP
EVIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVSVADAVATYLFNSQILTKPNG
KMMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRESMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLN
EWVDRYYRDRLTQNDLADPQLLREGREALDSLTTILGLGSVYPFQQ

Sequences:

>Translated_446_residues
MSGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQGVLPPQERPHVPMLRKLGFSG
SDESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADSADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFA
HHEALPQVALFGDEGAANHNRLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNP
EVIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVSVADAVATYLFNSQILTKPNG
KMMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRESMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLN
EWVDRYYRDRLTQNDLADPQLLREGREALDSLTTILGLGSVYPFQQ
>Mature_445_residues
SGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQGVLPPQERPHVPMLRKLGFSGS
DESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADSADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFAH
HEALPQVALFGDEGAANHNRLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNPE
VIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVSVADAVATYLFNSQILTKPNGK
MMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRESMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLNE
WVDRYYRDRLTQNDLADPQLLREGREALDSLTTILGLGSVYPFQQ

Specific function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

COG id: COG3724

COG function: function code E; Succinylarginine dihydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinylarginine dihydrolase family

Homologues:

Organism=Escherichia coli, GI1788041, Length=446, Percent_Identity=68.609865470852, Blast_Score=645, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTB_SERP5 (A8GFQ2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479070.1
- ProteinModelPortal:   A8GFQ2
- SMR:   A8GFQ2
- STRING:   A8GFQ2
- GeneID:   5603099
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2841
- eggNOG:   COG3724
- HOGENOM:   HBG289862
- OMA:   HFAHHPA
- ProtClustDB:   PRK13281
- BioCyc:   SPRO399741:SPRO_2841-MONOMER
- HAMAP:   MF_01172
- InterPro:   IPR007079
- Gene3D:   G3DSA:3.75.10.20
- TIGRFAMs:   TIGR03241

Pfam domain/function: PF04996 AstB

EC number: =3.5.3.23

Molecular weight: Translated: 49410; Mature: 49279

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 174-174 ACT_SITE 249-249 ACT_SITE 370-370 BINDING 110-110 BINDING 213-213 BINDING 251-251 BINDING 364-364

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQG
CCCCEECCCCCEEHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCHHCC
VLPPQERPHVPMLRKLGFSGSDESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADS
CCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHCCCCEEEECCCCEECCCCCC
ADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFAHHEALPQVALFGDEGAANHN
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCC
RLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNP
CCCCCCCCCEEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
EVIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVS
HHHHCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
VADAVATYLFNSQILTKPNGKMMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRE
HHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLNEWVDRYYRDRLTQNDLADPQ
HHHCCCCCEEEEEEEECCHHHHHHCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCCCHH
LLREGREALDSLTTILGLGSVYPFQQ
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQG
CCCEECCCCCEEHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCHHCC
VLPPQERPHVPMLRKLGFSGSDESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADS
CCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHCCCCEEEECCCCEECCCCCC
ADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFAHHEALPQVALFGDEGAANHN
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCC
RLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNP
CCCCCCCCCEEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
EVIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVS
HHHHCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
VADAVATYLFNSQILTKPNGKMMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRE
HHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLNEWVDRYYRDRLTQNDLADPQ
HHHCCCCCEEEEEEEECCHHHHHHCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCCCHH
LLREGREALDSLTTILGLGSVYPFQQ
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA