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The map label for this gene is rrmA [H]

Identifier: 157371060

GI number: 157371060

Start: 3101199

End: 3102020

Strand: Reverse

Name: rrmA [H]

Synonym: Spro_2820

Alternate gene names: 157371060

Gene position: 3102020-3101199 (Counterclockwise)

Preceding gene: 157371062

Following gene: 157371058

Centisome position: 56.93

GC content: 58.39

Gene sequence:

>822_bases
ATGTCTTATCAGTGCCCTCTGTGTCATCAGCCGCTTCATCTTTCTCATCTGCAATGGCGTTGCGACGCTAACCATCAGTT
TGACTGCGCCAAAGAAGGCTATGTCAACCTGCTGCCGGTACAGCACAAGCGCTCAAAGCAGCCCGGAGACAGTGCGGAAA
TGATGCAGGCGCGGCGTGCGTTCCTTGATGCGGGTTTCTATCAACCCTTGCAGCAGCGGGTGGCTGAGCTGTTGGATCAG
GCATTGGCGAGCGATGCGCAGGCGTTACTGGACATCGGCTGTGGCGAAGGCTATTACACGGCGGAAGTGGCTGCCCGGTT
GGCGCAGCAGCGTAATATCACCGTTTATGGCCTGGACGTCGCCAAGGTGGCGATCCGCTATGCGGCCAAGCGTTACCCGG
CAGTCTCATTCTGCGTGGCGTCGAGCCACCGGCTGCCGTTTGCTGATGCCTCTCTGGACGCCATACTGCGTATTTACGCC
CCTTGCAAAGCCGAAGAACTGGCTCGGGTAGTAAAACCCGGTGGGGTGGTGGTCACGGTATCGCCTGGCCCACGTCACCT
GTATCAATTGAAAGAGCAGGTGTATCAGCAGGTGCAACTGCATGTCGAACAGGATGAGCAGTTTGCCGGTTTTGACTGCG
AACGAGTGGAGTCATTGGCATACCCGATGACGCTGCCGGGTGAACAGGCGGCCAACCTGCTGCAGATGACGCCTTTCGCC
TGGCGCGCCTCGCCTGAGGTTCAGCAGCACCTGAGTGGCTGTGAGGCCTTCGCCTGCGAAACCGATTTTGTTATCGCGTT
GTACCGCCGCCAGCCCGATTAA

Upstream 100 bases:

>100_bases
AGTTTTTTTCCTCCCTGGCTAGGGGCTTGCGGCATCTGTCTTGCATCGTACAGAAGGCTTCTTTAGACTAGCCGCGCCGT
ATCTCTCTGGAATCCAAGCC

Downstream 100 bases:

>100_bases
ACTGGTGGACAGACGGCCGGGTCATTGGTCCGCTCGTCTTCCAGGCTGTCAGGGGTGAGGGCGAAATGCGTTTTCAACGC
CACCCAGCCCTTTGGCGTCA

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSYQCPLCHQPLHLSHLQWRCDANHQFDCAKEGYVNLLPVQHKRSKQPGDSAEMMQARRAFLDAGFYQPLQQRVAELLDQ
ALASDAQALLDIGCGEGYYTAEVAARLAQQRNITVYGLDVAKVAIRYAAKRYPAVSFCVASSHRLPFADASLDAILRIYA
PCKAEELARVVKPGGVVVTVSPGPRHLYQLKEQVYQQVQLHVEQDEQFAGFDCERVESLAYPMTLPGEQAANLLQMTPFA
WRASPEVQQHLSGCEAFACETDFVIALYRRQPD

Sequences:

>Translated_273_residues
MSYQCPLCHQPLHLSHLQWRCDANHQFDCAKEGYVNLLPVQHKRSKQPGDSAEMMQARRAFLDAGFYQPLQQRVAELLDQ
ALASDAQALLDIGCGEGYYTAEVAARLAQQRNITVYGLDVAKVAIRYAAKRYPAVSFCVASSHRLPFADASLDAILRIYA
PCKAEELARVVKPGGVVVTVSPGPRHLYQLKEQVYQQVQLHVEQDEQFAGFDCERVESLAYPMTLPGEQAANLLQMTPFA
WRASPEVQQHLSGCEAFACETDFVIALYRRQPD
>Mature_272_residues
SYQCPLCHQPLHLSHLQWRCDANHQFDCAKEGYVNLLPVQHKRSKQPGDSAEMMQARRAFLDAGFYQPLQQRVAELLDQA
LASDAQALLDIGCGEGYYTAEVAARLAQQRNITVYGLDVAKVAIRYAAKRYPAVSFCVASSHRLPFADASLDAILRIYAP
CKAEELARVVKPGGVVVTVSPGPRHLYQLKEQVYQQVQLHVEQDEQFAGFDCERVESLAYPMTLPGEQAANLLQMTPFAW
RASPEVQQHLSGCEAFACETDFVIALYRRQPD

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=270, Percent_Identity=63.7037037037037, Blast_Score=351, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30573; Mature: 30442

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQCPLCHQPLHLSHLQWRCDANHQFDCAKEGYVNLLPVQHKRSKQPGDSAEMMQARRA
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCHHCCCCCCCHHHHHHHHHH
FLDAGFYQPLQQRVAELLDQALASDAQALLDIGCGEGYYTAEVAARLAQQRNITVYGLDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHH
AKVAIRYAAKRYPAVSFCVASSHRLPFADASLDAILRIYAPCKAEELARVVKPGGVVVTV
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
SPGPRHLYQLKEQVYQQVQLHVEQDEQFAGFDCERVESLAYPMTLPGEQAANLLQMTPFA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCH
WRASPEVQQHLSGCEAFACETDFVIALYRRQPD
HCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
>Mature Secondary Structure 
SYQCPLCHQPLHLSHLQWRCDANHQFDCAKEGYVNLLPVQHKRSKQPGDSAEMMQARRA
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCHHCCCCCCCHHHHHHHHHH
FLDAGFYQPLQQRVAELLDQALASDAQALLDIGCGEGYYTAEVAARLAQQRNITVYGLDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHH
AKVAIRYAAKRYPAVSFCVASSHRLPFADASLDAILRIYAPCKAEELARVVKPGGVVVTV
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
SPGPRHLYQLKEQVYQQVQLHVEQDEQFAGFDCERVESLAYPMTLPGEQAANLLQMTPFA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCH
WRASPEVQQHLSGCEAFACETDFVIALYRRQPD
HCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]