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The map label for this gene is galU [H]

Identifier: 157370949

GI number: 157370949

Start: 2985728

End: 2986645

Strand: Reverse

Name: galU [H]

Synonym: Spro_2709

Alternate gene names: 157370949

Gene position: 2986645-2985728 (Counterclockwise)

Preceding gene: 157370950

Following gene: 157370948

Centisome position: 54.81

GC content: 51.96

Gene sequence:

>918_bases
ATGCCTGCTGTAAATCGTAAAGTCAGAAAGGCTGTGATCCCGGTTGCAGGCTTGGGAACACGGATGTTACCGGCGACAAA
AGCCATTCCTAAAGAAATGCTGCCGCTGGTTGACAAACCCTTGATCCAATACGTTGTCAATGAGTGTATTGCGGCAGGGA
TTAACGAAATTGTGTTGGTTACCCATTCCTCCAAGAATTCGATCGAAAACCATTTCGATACCAGTTTTGAACTGGAAGCG
ATGCTGGAAAAACGAGTTAAGCGTCAGTTGCTCGATGAAGTGCAGTCTATCTGTCCCAAGGGCGTTACCGTAATGCAGGT
GCGTCAGGGGGTGGCTAAAGGCTTGGGTCACGCGATTATGTGTGCCTATCCACTGGTGGGTGACGAACCGGTGGCGGTGA
TTTTGCCGGACGTGATCCTCGATGAGTACAGTTCCGATCTGAAAAAAGACAATCTGCACGAAATGCTGCAGCGCTTTGAG
CAAACCGGTATCAGCCAGATTATGGTGGAGCCTGTGCCGCATAAAGATGTTGGCAACTATGGCGTGGCCGATTGCAAAGG
GTATGAGCTGCAGCCGGGCGAAAGCGCCCCGATGGTTAGCGTGGTAGAGAAACCTTCGCCGGATGAAGCCCCTTCCAACC
TGGCCATTGTTGGCCGTTATGTGCTCTCCGCCGATATCTGGCCGCTGCTGTCGAAAACCCCTCCGGGTGCGGGTGGTGAA
ATCCAGCTGACCGACAGCATTGAAATGCTGATGCAGCAAGAGACGGTAGAGGCGTATCACCTGAAAGGGATCAGCCATGA
TTGCGGCAACAAGCTGGGTTATATGCAGGCATTTGTCGAGTATGGCATGCGCCATGCCGGGCTGGGCCAAGAGTTCACTC
AGTGGTTGAAACAGTTACTGGCCGCTGATAAAAAATAA

Upstream 100 bases:

>100_bases
GCGCTGCGGTTAATGCCAGTCAGTCATAAGCTGGTATACTCCGAGGGTTTTTGTATGGCGGATGAAGCTCATAAACTGAG
CGCTATTAAGAGAGGAAATA

Downstream 100 bases:

>100_bases
TTTATTCATCTTTCGTCTTAATTTGAAAAACTAGGATTTTCCCATGAAAGTAACAGTTTTTGGTATTGGCTATGTTGGCC
TGGTGCAGGCTGCGGTGTTG

Product: UTP--glucose-1-phosphate uridylyltransferase subunit GalU

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPAVNRKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIENHFDTSFELEA
MLEKRVKRQLLDEVQSICPKGVTVMQVRQGVAKGLGHAIMCAYPLVGDEPVAVILPDVILDEYSSDLKKDNLHEMLQRFE
QTGISQIMVEPVPHKDVGNYGVADCKGYELQPGESAPMVSVVEKPSPDEAPSNLAIVGRYVLSADIWPLLSKTPPGAGGE
IQLTDSIEMLMQQETVEAYHLKGISHDCGNKLGYMQAFVEYGMRHAGLGQEFTQWLKQLLAADKK

Sequences:

>Translated_305_residues
MPAVNRKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIENHFDTSFELEA
MLEKRVKRQLLDEVQSICPKGVTVMQVRQGVAKGLGHAIMCAYPLVGDEPVAVILPDVILDEYSSDLKKDNLHEMLQRFE
QTGISQIMVEPVPHKDVGNYGVADCKGYELQPGESAPMVSVVEKPSPDEAPSNLAIVGRYVLSADIWPLLSKTPPGAGGE
IQLTDSIEMLMQQETVEAYHLKGISHDCGNKLGYMQAFVEYGMRHAGLGQEFTQWLKQLLAADKK
>Mature_304_residues
PAVNRKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIENHFDTSFELEAM
LEKRVKRQLLDEVQSICPKGVTVMQVRQGVAKGLGHAIMCAYPLVGDEPVAVILPDVILDEYSSDLKKDNLHEMLQRFEQ
TGISQIMVEPVPHKDVGNYGVADCKGYELQPGESAPMVSVVEKPSPDEAPSNLAIVGRYVLSADIWPLLSKTPPGAGGEI
QLTDSIEMLMQQETVEAYHLKGISHDCGNKLGYMQAFVEYGMRHAGLGQEFTQWLKQLLAADKK

Specific function: May play a role in stationary phase survival [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=304, Percent_Identity=81.25, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1788355, Length=293, Percent_Identity=56.9965870307167, Blast_Score=341, Evalue=3e-95,
Organism=Escherichia coli, GI1788351, Length=252, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790224, Length=243, Percent_Identity=23.4567901234568, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33483; Mature: 33352

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVNRKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLV
CCCCHHHHHHHHCCHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
THSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPKGVTVMQVRQGVAKGLGHAIM
EECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
CAYPLVGDEPVAVILPDVILDEYSSDLKKDNLHEMLQRFEQTGISQIMVEPVPHKDVGNY
HEECCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCC
GVADCKGYELQPGESAPMVSVVEKPSPDEAPSNLAIVGRYVLSADIWPLLSKTPPGAGGE
CCCCCCCCCCCCCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
IQLTDSIEMLMQQETVEAYHLKGISHDCGNKLGYMQAFVEYGMRHAGLGQEFTQWLKQLL
EEEHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AADKK
HCCCC
>Mature Secondary Structure 
PAVNRKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLV
CCCHHHHHHHHCCHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
THSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPKGVTVMQVRQGVAKGLGHAIM
EECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
CAYPLVGDEPVAVILPDVILDEYSSDLKKDNLHEMLQRFEQTGISQIMVEPVPHKDVGNY
HEECCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCC
GVADCKGYELQPGESAPMVSVVEKPSPDEAPSNLAIVGRYVLSADIWPLLSKTPPGAGGE
CCCCCCCCCCCCCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
IQLTDSIEMLMQQETVEAYHLKGISHDCGNKLGYMQAFVEYGMRHAGLGQEFTQWLKQLL
EEEHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AADKK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]