| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is ftsI [H]
Identifier: 157370597
GI number: 157370597
Start: 2570391
End: 2572109
Strand: Direct
Name: ftsI [H]
Synonym: Spro_2357
Alternate gene names: 157370597
Gene position: 2570391-2572109 (Clockwise)
Preceding gene: 157370596
Following gene: 157370600
Centisome position: 47.17
GC content: 56.08
Gene sequence:
>1719_bases GTGGCGCCATTAATAAAAAAAAGCGGTAAAAATTATTCAACCCTTCGCTTTGGCTGGATTTGCGCCGGGATACTGGTTTG CTTTTTCCTGCTGGCGTTTCGAGTGGGCTATTTACAACTGTTGGAGCATCAACAACTGACTGACCAGGCGGATCAGCGTT CGATCCGCACCCAGGTGTTGCCGACCAACCGGGGGATGATCACCGATCGCAATGGTGAAGCGCTGGCCGTGAGCGTGTCT TCACGCGATATCGTGCTGGATCCCAAACATATTCTCGATAGCCATGCCGACCTCACCAATGAACGTTGGCAGAGCCTGGC CAATGTGCTGAAAATGCCGCTGACCGAGGTGCAAAAACAGATCCAGACCAACGCCCATAAGCGTTTTGTCTATCTGGCCC GTAAGGTTGAAGATGATAATGCCAGTTATATCAGTAAGCTGCATTTGACCGGCGTCAGCACCGAGCAGGACTTCAGCCGC TTTTATCCGATGAGCCAGGATACCGCCGGGCTGATCGGTATTGTCGGACAGGATAATCAGGGGCTGGAAGGCATCGAGCT GGGCTTTAACCACCTGCTGCAAGGCAAGAACGGATTGCGCGTGTACCAGAAGGATGGCAGCGGGGCGGTGATTGGCGTGA TCAAGAACGTCGATCCTGTGCCGCCGCCGAACGTCACGCTGAGCATCGACAAATTTATCCAGTACGTGCTGTATGCGCAG ATCCGCGACGGCGTGGTCGCCAACCAGGCAGACTCCGGTTGCGCCGTGCTGGTGAAGGTGAACACCGGCGAGGTGCTGGG CATGGCCAGCTACCCGTCATTTAACCCAAACAACTATGCGGATACGCCGTCAAAAGATATTCGCAACGTATGCAGCAGCG ACAGTTTCGAGCCAGGCTCCACGGTAAAACCCGTGGTGGTGATGGTTGGGCTGGAGCACCACTTAATCAGGCCGGATACC GTGCTGGATACCACGCCTTACCGGGTCAATGGTCATTTAATCAAGGACGTGGGCCACTGGTCGAAACTGACCATTACCGG GGTACTGCAAAAATCCAGTGACATCGCCGTTTCACATATCGCGCTGGCACTGCCTGCCACCGTGTTGCCGGCCGTTTACA AAAGCTTTGGCCTGGGGCTGCCGACTGACCTGGGGATTGGTAACGAGAGCAGCGGCTACCTGCCGCAGCACCGTGAGCGC TGGGCGGATATCGAACGGGCGACCTTCTCCTTCGGCTATGGCCTGCGGGTAACGCCGCTACAGATGGCGCGTGAATATGC GACCATCGGTTCCTATGGCGTTTATCGGCCATTGTCGATAACTAAAGTCACGCCACCGGTAATGGGGCAGCGCATCCTGC CGGAGGATACGGTAAAAACCGTGGTGCATATGATGGAAAGCGATGCTTTACCGGGTGGCAGCGGGCTCAGCGCCGCAGTG CCGGGGTACCGGTTGGCGATTAAAACCGGTACCGCAGAGAAGATGGGGCCTAATGGCAAATACGACGGCGGTTACATCAA CTACACCGCCGGTGTCGCCCCGGCCAGCGATCCGCAGGTAGCGCTGGTGGTAATGGTTAACAACCCGAAAGCCGGCAAAC ACTTCGGTGGTTCGGTAGCCGGCCCGGTGTTTGGCAAAATCATGGCTCAGGTTCTGGAACATATGAATATCCTGCCCGAT GCCCAACCGTTGAATGTGGTGTCTCAGGTTAAGGGCTAA
Upstream 100 bases:
>100_bases GCGTTTGTTTTTACTTTCTTACAAACTGCAATCTTCTAAAGATTTTCGTCAGGTTAGACTGAAATCATTACATAACCTTA ATAAAAACGCAGGGTTAACA
Downstream 100 bases:
>100_bases CACCATCTTCCCCCTCGCTGGAGGGGGAAAAGGATCAGAAGTAATAGCCAATGTTCAGGTTAGTGCGGAAATACCATTTA TTGCTGCCGGAAGACTGAGT
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 572; Mature: 571
Protein sequence:
>572_residues MAPLIKKSGKNYSTLRFGWICAGILVCFFLLAFRVGYLQLLEHQQLTDQADQRSIRTQVLPTNRGMITDRNGEALAVSVS SRDIVLDPKHILDSHADLTNERWQSLANVLKMPLTEVQKQIQTNAHKRFVYLARKVEDDNASYISKLHLTGVSTEQDFSR FYPMSQDTAGLIGIVGQDNQGLEGIELGFNHLLQGKNGLRVYQKDGSGAVIGVIKNVDPVPPPNVTLSIDKFIQYVLYAQ IRDGVVANQADSGCAVLVKVNTGEVLGMASYPSFNPNNYADTPSKDIRNVCSSDSFEPGSTVKPVVVMVGLEHHLIRPDT VLDTTPYRVNGHLIKDVGHWSKLTITGVLQKSSDIAVSHIALALPATVLPAVYKSFGLGLPTDLGIGNESSGYLPQHRER WADIERATFSFGYGLRVTPLQMAREYATIGSYGVYRPLSITKVTPPVMGQRILPEDTVKTVVHMMESDALPGGSGLSAAV PGYRLAIKTGTAEKMGPNGKYDGGYINYTAGVAPASDPQVALVVMVNNPKAGKHFGGSVAGPVFGKIMAQVLEHMNILPD AQPLNVVSQVKG
Sequences:
>Translated_572_residues MAPLIKKSGKNYSTLRFGWICAGILVCFFLLAFRVGYLQLLEHQQLTDQADQRSIRTQVLPTNRGMITDRNGEALAVSVS SRDIVLDPKHILDSHADLTNERWQSLANVLKMPLTEVQKQIQTNAHKRFVYLARKVEDDNASYISKLHLTGVSTEQDFSR FYPMSQDTAGLIGIVGQDNQGLEGIELGFNHLLQGKNGLRVYQKDGSGAVIGVIKNVDPVPPPNVTLSIDKFIQYVLYAQ IRDGVVANQADSGCAVLVKVNTGEVLGMASYPSFNPNNYADTPSKDIRNVCSSDSFEPGSTVKPVVVMVGLEHHLIRPDT VLDTTPYRVNGHLIKDVGHWSKLTITGVLQKSSDIAVSHIALALPATVLPAVYKSFGLGLPTDLGIGNESSGYLPQHRER WADIERATFSFGYGLRVTPLQMAREYATIGSYGVYRPLSITKVTPPVMGQRILPEDTVKTVVHMMESDALPGGSGLSAAV PGYRLAIKTGTAEKMGPNGKYDGGYINYTAGVAPASDPQVALVVMVNNPKAGKHFGGSVAGPVFGKIMAQVLEHMNILPD AQPLNVVSQVKG >Mature_571_residues APLIKKSGKNYSTLRFGWICAGILVCFFLLAFRVGYLQLLEHQQLTDQADQRSIRTQVLPTNRGMITDRNGEALAVSVSS RDIVLDPKHILDSHADLTNERWQSLANVLKMPLTEVQKQIQTNAHKRFVYLARKVEDDNASYISKLHLTGVSTEQDFSRF YPMSQDTAGLIGIVGQDNQGLEGIELGFNHLLQGKNGLRVYQKDGSGAVIGVIKNVDPVPPPNVTLSIDKFIQYVLYAQI RDGVVANQADSGCAVLVKVNTGEVLGMASYPSFNPNNYADTPSKDIRNVCSSDSFEPGSTVKPVVVMVGLEHHLIRPDTV LDTTPYRVNGHLIKDVGHWSKLTITGVLQKSSDIAVSHIALALPATVLPAVYKSFGLGLPTDLGIGNESSGYLPQHRERW ADIERATFSFGYGLRVTPLQMAREYATIGSYGVYRPLSITKVTPPVMGQRILPEDTVKTVVHMMESDALPGGSGLSAAVP GYRLAIKTGTAEKMGPNGKYDGGYINYTAGVAPASDPQVALVVMVNNPKAGKHFGGSVAGPVFGKIMAQVLEHMNILPDA QPLNVVSQVKG
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=559, Percent_Identity=53.309481216458, Blast_Score=605, Evalue=1e-174, Organism=Escherichia coli, GI1786854, Length=613, Percent_Identity=23.8172920065253, Blast_Score=107, Evalue=2e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 62018; Mature: 61887
Theoretical pI: Translated: 8.51; Mature: 8.51
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAPLIKKSGKNYSTLRFGWICAGILVCFFLLAFRVGYLQLLEHQQLTDQADQRSIRTQVL CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE PTNRGMITDRNGEALAVSVSSRDIVLDPKHILDSHADLTNERWQSLANVLKMPLTEVQKQ ECCCCEEECCCCCEEEEEECCCCEEECHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHH IQTNAHKRFVYLARKVEDDNASYISKLHLTGVSTEQDFSRFYPMSQDTAGLIGIVGQDNQ HHHHHHHEEEEEEECCCCCCHHHHHEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCCC GLEGIELGFNHLLQGKNGLRVYQKDGSGAVIGVIKNVDPVPPPNVTLSIDKFIQYVLYAQ CCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHH IRDGVVANQADSGCAVLVKVNTGEVLGMASYPSFNPNNYADTPSKDIRNVCSSDSFEPGS HHCCEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC TVKPVVVMVGLEHHLIRPDTVLDTTPYRVNGHLIKDVGHWSKLTITGVLQKSSDIAVSHI CCCCEEEEEECHHHEECCCCEECCCCEEECCEEEECCCCCCEEEEEEEEECCCCHHHHHH ALALPATVLPAVYKSFGLGLPTDLGIGNESSGYLPQHRERWADIERATFSFGYGLRVTPL HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEECHH QMAREYATIGSYGVYRPLSITKVTPPVMGQRILPEDTVKTVVHMMESDALPGGSGLSAAV HHHHHHHHHCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC PGYRLAIKTGTAEKMGPNGKYDGGYINYTAGVAPASDPQVALVVMVNNPKAGKHFGGSVA CCEEEEEECCCCHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCC GPVFGKIMAQVLEHMNILPDAQPLNVVSQVKG HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC >Mature Secondary Structure APLIKKSGKNYSTLRFGWICAGILVCFFLLAFRVGYLQLLEHQQLTDQADQRSIRTQVL CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE PTNRGMITDRNGEALAVSVSSRDIVLDPKHILDSHADLTNERWQSLANVLKMPLTEVQKQ ECCCCEEECCCCCEEEEEECCCCEEECHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHH IQTNAHKRFVYLARKVEDDNASYISKLHLTGVSTEQDFSRFYPMSQDTAGLIGIVGQDNQ HHHHHHHEEEEEEECCCCCCHHHHHEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCCC GLEGIELGFNHLLQGKNGLRVYQKDGSGAVIGVIKNVDPVPPPNVTLSIDKFIQYVLYAQ CCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHH IRDGVVANQADSGCAVLVKVNTGEVLGMASYPSFNPNNYADTPSKDIRNVCSSDSFEPGS HHCCEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC TVKPVVVMVGLEHHLIRPDTVLDTTPYRVNGHLIKDVGHWSKLTITGVLQKSSDIAVSHI CCCCEEEEEECHHHEECCCCEECCCCEEECCEEEECCCCCCEEEEEEEEECCCCHHHHHH ALALPATVLPAVYKSFGLGLPTDLGIGNESSGYLPQHRERWADIERATFSFGYGLRVTPL HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEECHH QMAREYATIGSYGVYRPLSITKVTPPVMGQRILPEDTVKTVVHMMESDALPGGSGLSAAV HHHHHHHHHCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC PGYRLAIKTGTAEKMGPNGKYDGGYINYTAGVAPASDPQVALVVMVNNPKAGKHFGGSVA CCEEEEEECCCCHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCC GPVFGKIMAQVLEHMNILPDAQPLNVVSQVKG HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]