Click here to switch to the map view.

The map label for this gene is 157370573

Identifier: 157370573

GI number: 157370573

Start: 2545643

End: 2547247

Strand: Reverse

Name: 157370573

Synonym: Spro_2333

Alternate gene names: NA

Gene position: 2547247-2545643 (Counterclockwise)

Preceding gene: 157370574

Following gene: 157370572

Centisome position: 46.75

GC content: 52.59

Gene sequence:

>1605_bases
ATGGCCATTGAATATGATTGCGACATTCTCGTCGTGGGTGCCGGTATTCTGGGCGGAGCCGTCGCCAACAGCCTTGCCAA
ACAGGGACGATCAGTCACCATTTTAGAGGCTGGCCCTCGCGTTAAGCGTTCGGAAATCCTTGAAGCATTTCGCCAATATG
GCAATAAATCGGACTATAACGGCCCTTACCCTGACGTACCCTGGGCGCCAAAATCCGCTTCGGGTAAATATTCTGACGAC
TATATCGAGAGCGTCGGCAATATCACCCAAAAGCCTGCTTTCTTGCGTTTGGTCGGTGGAACCACCTGGCACTGGGGCGG
TGCAACCTGGCGGAATCTGCCCAGCGATTTCAAATTAAAAACGCTGTACGGTCATGGCCGTGACTGGCCGATTGACTACG
ATATGCTGGAACCCTGGTATCAACAGGCTGAAGAAGAGATTGGCGTGAGTGGTTCAAACACCGACGATCAGCGAGGTCTG
GGGCAACAACCTTATCCCCCGCGCTCTAAACCTTATCCCATGGCAATGCAGCCCTGGAGCTATTTGACTCAGCAAGTGGC
CGAAAAGGTATCAACAGTCAATCACCACTTTGTTGATGAACCTAATGCACGCGCGACGCGCCCCTATCAAGGGCGACCGA
TCTGCGCGGGCAACAATAACTGTGCGCCTATCTGCCCAATTGGTGCACAGTTCTCCGGCGATAAACCTGTTGTATGGGCC
GAACAGAATGGCGCTAAACTGTTAGTCAATGCAGTGGCTTACCGCATTGAAAAAGGACCGGATAACAAGATTGTCGCTAT
CCACTATAAAAATCCGCAGGGTGAAAGCACACGCCTTACTGCACGTTACTTCGTATTGGCAGCACATGGGGTAGAAACGC
CGAAACTGATGCTGATGTCGGACATCGGTAATTCGTCCGATCAGGTAGGTCGTAACATGATGGGGCACACCGGGCGGTCT
ATCTCTATGCTGGCGAAAGATCCCGTTTGGGCGGGACGTGGTCCCACGCAACAAGGAAGCATCAACACCTGGCGCGACAC
GCCGCTGCGGCACCAGCATGCGGCTATTCGCCACTTCCTGGATAATACCGTTCCTAACGAACTGATTACCCTCCGGTTGC
TGAGTCAAGGTATTGTAGGCCCGGAGCTTGATCGTTTGATCCGCCACAATTCCGCGCGCTACCTGAAGATTGCATCTTAC
GTCGAGGTATTGCCCGATCCGACCAACAGGGTCACCCTGAGCAATAAGCGCGATGCACTGGGTCTTCCTACGCCACGCAT
CAACTATGACATTGCCCATGAATACACCATGAACGCCATGGCTTTGCTCTATAAAGACTATGACCAATTCAGGAGTCTGT
TCGGTGCGACCGAGGTGCTGAATGATATTCAGGCTTGGGTACCAAGTTCCCATATCATGGGCACCACCATTATGGGGAGT
GACCCACGGGACTCCGTGGTCAACCATGAATGCCGCTCTTTCGATCATGCCAACCTCTTTATCACCAGTACCAGCGTACA
CCCCAGTTCCACCGTGGTTAACCCAACTCTGACCGGTTATGCGATTGCGCTGCGCGTCGCCGATATTATTAATAAAGAGA
TTTAA

Upstream 100 bases:

>100_bases
ACCATTGATGTCACCGTGATCCCTACTTATATCCGCGCCCAGCCTAATTACTGGGTGGCTACGCCAAATTTAGACAATTA
AAAATTTATAGTGAGCAAAT

Downstream 100 bases:

>100_bases
TAACGCATCGCCGTTGCGCTGGCAGGGCTGAACCGCAGCGCACTGGCCGATGTCACGTCTGGCAATGCGCCATTCGTCGC
TCCAACCGCAGATAATCCGA

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MAIEYDCDILVVGAGILGGAVANSLAKQGRSVTILEAGPRVKRSEILEAFRQYGNKSDYNGPYPDVPWAPKSASGKYSDD
YIESVGNITQKPAFLRLVGGTTWHWGGATWRNLPSDFKLKTLYGHGRDWPIDYDMLEPWYQQAEEEIGVSGSNTDDQRGL
GQQPYPPRSKPYPMAMQPWSYLTQQVAEKVSTVNHHFVDEPNARATRPYQGRPICAGNNNCAPICPIGAQFSGDKPVVWA
EQNGAKLLVNAVAYRIEKGPDNKIVAIHYKNPQGESTRLTARYFVLAAHGVETPKLMLMSDIGNSSDQVGRNMMGHTGRS
ISMLAKDPVWAGRGPTQQGSINTWRDTPLRHQHAAIRHFLDNTVPNELITLRLLSQGIVGPELDRLIRHNSARYLKIASY
VEVLPDPTNRVTLSNKRDALGLPTPRINYDIAHEYTMNAMALLYKDYDQFRSLFGATEVLNDIQAWVPSSHIMGTTIMGS
DPRDSVVNHECRSFDHANLFITSTSVHPSSTVVNPTLTGYAIALRVADIINKEI

Sequences:

>Translated_534_residues
MAIEYDCDILVVGAGILGGAVANSLAKQGRSVTILEAGPRVKRSEILEAFRQYGNKSDYNGPYPDVPWAPKSASGKYSDD
YIESVGNITQKPAFLRLVGGTTWHWGGATWRNLPSDFKLKTLYGHGRDWPIDYDMLEPWYQQAEEEIGVSGSNTDDQRGL
GQQPYPPRSKPYPMAMQPWSYLTQQVAEKVSTVNHHFVDEPNARATRPYQGRPICAGNNNCAPICPIGAQFSGDKPVVWA
EQNGAKLLVNAVAYRIEKGPDNKIVAIHYKNPQGESTRLTARYFVLAAHGVETPKLMLMSDIGNSSDQVGRNMMGHTGRS
ISMLAKDPVWAGRGPTQQGSINTWRDTPLRHQHAAIRHFLDNTVPNELITLRLLSQGIVGPELDRLIRHNSARYLKIASY
VEVLPDPTNRVTLSNKRDALGLPTPRINYDIAHEYTMNAMALLYKDYDQFRSLFGATEVLNDIQAWVPSSHIMGTTIMGS
DPRDSVVNHECRSFDHANLFITSTSVHPSSTVVNPTLTGYAIALRVADIINKEI
>Mature_533_residues
AIEYDCDILVVGAGILGGAVANSLAKQGRSVTILEAGPRVKRSEILEAFRQYGNKSDYNGPYPDVPWAPKSASGKYSDDY
IESVGNITQKPAFLRLVGGTTWHWGGATWRNLPSDFKLKTLYGHGRDWPIDYDMLEPWYQQAEEEIGVSGSNTDDQRGLG
QQPYPPRSKPYPMAMQPWSYLTQQVAEKVSTVNHHFVDEPNARATRPYQGRPICAGNNNCAPICPIGAQFSGDKPVVWAE
QNGAKLLVNAVAYRIEKGPDNKIVAIHYKNPQGESTRLTARYFVLAAHGVETPKLMLMSDIGNSSDQVGRNMMGHTGRSI
SMLAKDPVWAGRGPTQQGSINTWRDTPLRHQHAAIRHFLDNTVPNELITLRLLSQGIVGPELDRLIRHNSARYLKIASYV
EVLPDPTNRVTLSNKRDALGLPTPRINYDIAHEYTMNAMALLYKDYDQFRSLFGATEVLNDIQAWVPSSHIMGTTIMGSD
PRDSVVNHECRSFDHANLFITSTSVHPSSTVVNPTLTGYAIALRVADIINKEI

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 59240; Mature: 59108

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEYDCDILVVGAGILGGAVANSLAKQGRSVTILEAGPRVKRSEILEAFRQYGNKSDYN
CEEEECCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
GPYPDVPWAPKSASGKYSDDYIESVGNITQKPAFLRLVGGTTWHWGGATWRNLPSDFKLK
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCHHHCCCCCCEEE
TLYGHGRDWPIDYDMLEPWYQQAEEEIGVSGSNTDDQRGLGQQPYPPRSKPYPMAMQPWS
EEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHH
YLTQQVAEKVSTVNHHFVDEPNARATRPYQGRPICAGNNNCAPICPIGAQFSGDKPVVWA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCCEEEE
EQNGAKLLVNAVAYRIEKGPDNKIVAIHYKNPQGESTRLTARYFVLAAHGVETPKLMLMS
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCEEEEE
DIGNSSDQVGRNMMGHTGRSISMLAKDPVWAGRGPTQQGSINTWRDTPLRHQHAAIRHFL
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DNTVPNELITLRLLSQGIVGPELDRLIRHNSARYLKIASYVEVLPDPTNRVTLSNKRDAL
HCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHCCCCCCEEEECCCCCCC
GLPTPRINYDIAHEYTMNAMALLYKDYDQFRSLFGATEVLNDIQAWVPSSHIMGTTIMGS
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DPRDSVVNHECRSFDHANLFITSTSVHPSSTVVNPTLTGYAIALRVADIINKEI
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIEYDCDILVVGAGILGGAVANSLAKQGRSVTILEAGPRVKRSEILEAFRQYGNKSDYN
EEEECCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
GPYPDVPWAPKSASGKYSDDYIESVGNITQKPAFLRLVGGTTWHWGGATWRNLPSDFKLK
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCHHHCCCCCCEEE
TLYGHGRDWPIDYDMLEPWYQQAEEEIGVSGSNTDDQRGLGQQPYPPRSKPYPMAMQPWS
EEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHH
YLTQQVAEKVSTVNHHFVDEPNARATRPYQGRPICAGNNNCAPICPIGAQFSGDKPVVWA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCCEEEE
EQNGAKLLVNAVAYRIEKGPDNKIVAIHYKNPQGESTRLTARYFVLAAHGVETPKLMLMS
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCEEEEE
DIGNSSDQVGRNMMGHTGRSISMLAKDPVWAGRGPTQQGSINTWRDTPLRHQHAAIRHFL
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DNTVPNELITLRLLSQGIVGPELDRLIRHNSARYLKIASYVEVLPDPTNRVTLSNKRDAL
HCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHCCCCCCEEEECCCCCCC
GLPTPRINYDIAHEYTMNAMALLYKDYDQFRSLFGATEVLNDIQAWVPSSHIMGTTIMGS
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DPRDSVVNHECRSFDHANLFITSTSVHPSSTVVNPTLTGYAIALRVADIINKEI
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]