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The map label for this gene is hcrC [H]

Identifier: 157370540

GI number: 157370540

Start: 2504082

End: 2505512

Strand: Direct

Name: hcrC [H]

Synonym: Spro_2300

Alternate gene names: 157370540

Gene position: 2504082-2505512 (Clockwise)

Preceding gene: 157370539

Following gene: 157370541

Centisome position: 45.96

GC content: 60.17

Gene sequence:

>1431_bases
ATGATCCAGTTTCTGCTTAATCAAACGCTGAAAAATGAAAGCGCGATCGACCCCAATACCACGGTGCTTAATTATCTGCG
CCGCGATCTCGGCCGCTGTGGCACCAAAGAAGGTTGCGCTTCCGGCGACTGTGGCGCCTGCACCGTGGTGCTGGCGGAGC
CGGACGGCGAAGGGTTGCGCTATCGCAGCGTTAACGCCTGCCTGACGTTTGTCAGTGCGCTGCATGGCAAGCAGTTGATC
ACCGTAGAGGACCTGAAACAGCAGGGCCAATTGCACAGCGTGCAGCAGGCGATGGTCGACTGCCATGGATCGCAGTGCGG
TTTTTGCACTCCGGGCTTCGTGATGTCGATGTTCTGTCTGCAAAAAAACGGTGAAGCCTATCAGCGTGAACAGGCGCAGC
AGGCACTAGCCGGTAATCTGTGCCGCTGTACCGGTTACCGGCCTATTTTGGCGGCGGCGCAGCAGGCGTGCGACAGCAAA
ACGCCAGACAACTTCGACCGTCATCAACAGCAAACCTTGCAACAACTGCGGACTATCCCGGCGGCGACGCCGCTGGAGGC
AGCGGGGAAACGCTGTCTGCTGCCGCAAAGCCTTGATGAACTGGCGACGCTGTATCTACAGCATCCGCAGGCCAAACTGT
TGGCCGGTGGCACCGATCTGGCTTTGGAAGTCACCCAGCGGCATCAGGATTTACCCTTGATGATCGCCATTGGCCAGATT
GAGGCGTTAAAACAGATTCGTCGGCACGACGATCGTCTGATTATTGGTGCCGGGGCGGCGTTGAGTGACCTTTACCCGCT
GTTGGCCGATTACCACCCGGCCTTTGGCGAACTGTTGGCGCGTTTTGCTTCGCAGCAGATCCGCAACCAGGGCACGCTGG
GGGGCAATATCGGCAACGCTTCGCCGATTGGCGACGCAGCGCCGCTGCTGCTGGCGCTGGATGCGCGCCTGATGTTGCGC
TGTGGCACCGTGCGGCGTGAACTACCGCTGAACGACTTCTTCCTGGGCTATCGCCAGACCGCGCTGCAGCCGGGGGAGTT
TATTGAAAGCATCGTGCTGCCGGGCCAGGCACCGGCGGATTTCCGCGCCTGGAAAGTCTCCAAGCGGCTGGAGGATGATA
TTTCGGCGGTGTGCGGTGCCTTCAACCTGACGATTGAACAGGGGATTATCCGCGATGCCCGGCTGGCCTTTGGTGGCATG
GCCGCGACGCCGAAACTCGCCATATTGTGCGAACGGCAACTGGTGGGGCAGCCGTGGCGGCGGGCTACCCTGGAGCTTGC
GGTTCAGGCGCTGGCGCAGGACTTCACCCCGCTGAGCGATTTCCGTGCCAGCAGCGCTTATCGCCTGTTGGTGGCGCAGA
ATCTGTTGCGTCGCTATTTCATTGCGCTGACTGAGCCACAGCTGGCGATCGAGGTGACGGCTTATGAGTAA

Upstream 100 bases:

>100_bases
AACTGTTTGTGTTGATGACGCTGGGCGATGACCGCAACGTTTACCGAACCTACGTCGACGGTAAAGTGGTGTACCGACCG
GCTACGCAGCAGGAGGCGGC

Downstream 100 bases:

>100_bases
TAGCAAACGCACCGAATATACCCAGCAGCAGTTGGCCGAACGTTTCCGTCAGCCGCTGCCCAGCGGCGTGGGGCGCAGTC
GCAAACACGAGAGCGCCGAC

Product: xanthine dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIQFLLNQTLKNESAIDPNTTVLNYLRRDLGRCGTKEGCASGDCGACTVVLAEPDGEGLRYRSVNACLTFVSALHGKQLI
TVEDLKQQGQLHSVQQAMVDCHGSQCGFCTPGFVMSMFCLQKNGEAYQREQAQQALAGNLCRCTGYRPILAAAQQACDSK
TPDNFDRHQQQTLQQLRTIPAATPLEAAGKRCLLPQSLDELATLYLQHPQAKLLAGGTDLALEVTQRHQDLPLMIAIGQI
EALKQIRRHDDRLIIGAGAALSDLYPLLADYHPAFGELLARFASQQIRNQGTLGGNIGNASPIGDAAPLLLALDARLMLR
CGTVRRELPLNDFFLGYRQTALQPGEFIESIVLPGQAPADFRAWKVSKRLEDDISAVCGAFNLTIEQGIIRDARLAFGGM
AATPKLAILCERQLVGQPWRRATLELAVQALAQDFTPLSDFRASSAYRLLVAQNLLRRYFIALTEPQLAIEVTAYE

Sequences:

>Translated_476_residues
MIQFLLNQTLKNESAIDPNTTVLNYLRRDLGRCGTKEGCASGDCGACTVVLAEPDGEGLRYRSVNACLTFVSALHGKQLI
TVEDLKQQGQLHSVQQAMVDCHGSQCGFCTPGFVMSMFCLQKNGEAYQREQAQQALAGNLCRCTGYRPILAAAQQACDSK
TPDNFDRHQQQTLQQLRTIPAATPLEAAGKRCLLPQSLDELATLYLQHPQAKLLAGGTDLALEVTQRHQDLPLMIAIGQI
EALKQIRRHDDRLIIGAGAALSDLYPLLADYHPAFGELLARFASQQIRNQGTLGGNIGNASPIGDAAPLLLALDARLMLR
CGTVRRELPLNDFFLGYRQTALQPGEFIESIVLPGQAPADFRAWKVSKRLEDDISAVCGAFNLTIEQGIIRDARLAFGGM
AATPKLAILCERQLVGQPWRRATLELAVQALAQDFTPLSDFRASSAYRLLVAQNLLRRYFIALTEPQLAIEVTAYE
>Mature_476_residues
MIQFLLNQTLKNESAIDPNTTVLNYLRRDLGRCGTKEGCASGDCGACTVVLAEPDGEGLRYRSVNACLTFVSALHGKQLI
TVEDLKQQGQLHSVQQAMVDCHGSQCGFCTPGFVMSMFCLQKNGEAYQREQAQQALAGNLCRCTGYRPILAAAQQACDSK
TPDNFDRHQQQTLQQLRTIPAATPLEAAGKRCLLPQSLDELATLYLQHPQAKLLAGGTDLALEVTQRHQDLPLMIAIGQI
EALKQIRRHDDRLIIGAGAALSDLYPLLADYHPAFGELLARFASQQIRNQGTLGGNIGNASPIGDAAPLLLALDARLMLR
CGTVRRELPLNDFFLGYRQTALQPGEFIESIVLPGQAPADFRAWKVSKRLEDDISAVCGAFNLTIEQGIIRDARLAFGGM
AATPKLAILCERQLVGQPWRRATLELAVQALAQDFTPLSDFRASSAYRLLVAQNLLRRYFIALTEPQLAIEVTAYE

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=488, Percent_Identity=33.8114754098361, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI71773480, Length=521, Percent_Identity=30.3262955854127, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1789231, Length=267, Percent_Identity=30.3370786516854, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786480, Length=156, Percent_Identity=33.974358974359, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789232, Length=132, Percent_Identity=37.8787878787879, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=542, Percent_Identity=30.6273062730627, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI32566215, Length=368, Percent_Identity=29.0760869565217, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=365, Percent_Identity=29.8630136986301, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17737937, Length=528, Percent_Identity=33.7121212121212, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24647197, Length=507, Percent_Identity=29.585798816568, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24647199, Length=492, Percent_Identity=28.6585365853659, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24647201, Length=488, Percent_Identity=27.0491803278689, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24647195, Length=326, Percent_Identity=33.1288343558282, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24647193, Length=497, Percent_Identity=28.3702213279678, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 52105; Mature: 52105

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFLLNQTLKNESAIDPNTTVLNYLRRDLGRCGTKEGCASGDCGACTVVLAEPDGEGLR
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCE
YRSVNACLTFVSALHGKQLITVEDLKQQGQLHSVQQAMVDCHGSQCGFCTPGFVMSMFCL
EHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QKNGEAYQREQAQQALAGNLCRCTGYRPILAAAQQACDSKTPDNFDRHQQQTLQQLRTIP
HCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
AATPLEAAGKRCLLPQSLDELATLYLQHPQAKLLAGGTDLALEVTQRHQDLPLMIAIGQI
CCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHEEECCCCCEEEEHHCCCCCCEEEEHHHH
EALKQIRRHDDRLIIGAGAALSDLYPLLADYHPAFGELLARFASQQIRNQGTLGGNIGNA
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SPIGDAAPLLLALDARLMLRCGTVRRELPLNDFFLGYRQTALQPGEFIESIVLPGQAPAD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
FRAWKVSKRLEDDISAVCGAFNLTIEQGIIRDARLAFGGMAATPKLAILCERQLVGQPWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECHHHHCCCHH
RATLELAVQALAQDFTPLSDFRASSAYRLLVAQNLLRRYFIALTEPQLAIEVTAYE
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MIQFLLNQTLKNESAIDPNTTVLNYLRRDLGRCGTKEGCASGDCGACTVVLAEPDGEGLR
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCE
YRSVNACLTFVSALHGKQLITVEDLKQQGQLHSVQQAMVDCHGSQCGFCTPGFVMSMFCL
EHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QKNGEAYQREQAQQALAGNLCRCTGYRPILAAAQQACDSKTPDNFDRHQQQTLQQLRTIP
HCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
AATPLEAAGKRCLLPQSLDELATLYLQHPQAKLLAGGTDLALEVTQRHQDLPLMIAIGQI
CCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHEEECCCCCEEEEHHCCCCCCEEEEHHHH
EALKQIRRHDDRLIIGAGAALSDLYPLLADYHPAFGELLARFASQQIRNQGTLGGNIGNA
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SPIGDAAPLLLALDARLMLRCGTVRRELPLNDFFLGYRQTALQPGEFIESIVLPGQAPAD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
FRAWKVSKRLEDDISAVCGAFNLTIEQGIIRDARLAFGGMAATPKLAILCERQLVGQPWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECHHHHCCCHH
RATLELAVQALAQDFTPLSDFRASSAYRLLVAQNLLRRYFIALTEPQLAIEVTAYE
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]