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The map label for this gene is tus [H]

Identifier: 157370520

GI number: 157370520

Start: 2482979

End: 2483917

Strand: Reverse

Name: tus [H]

Synonym: Spro_2280

Alternate gene names: 157370520

Gene position: 2483917-2482979 (Counterclockwise)

Preceding gene: 157370521

Following gene: 157370517

Centisome position: 45.59

GC content: 54.85

Gene sequence:

>939_bases
ATGGATAAATACGATTTAATAGGTAGGATGAATGCTTGTTTCAGCGAACTGGAACAGGCACTAACGGGCCTCCACCAGCA
GATCCTGCCATTGCGCTTGCTGGCTGGGCGGGTGTTTAGCCTGCCCGAAATAGAGAAAGGCAAGGAACATGACGCGGTGG
CGCAGATTGCCGTCGAACAGCATGTTGGCCTGGCCGCACGCGATTTGGCGCTGGAGCACTATCAGCGGCTGTTTATCCAT
CACAACAAGCACAACATCAGTAGCAAAGCGGCAGTGCGCCTGCCCGGTGTCATTTGCCTGGCGGTGGAGCAACCGGATTT
CCTGGCGCTGCAACAGCAAATTGCCCTGATTAACCGACTGAAGGCCGAACTGGAACAGATCATCACCGTCGACTCCGGCC
TGGCACCGGAGCAACGCTTTGACTTTGTCCATACTCACCTGCATGGCTTAATCACCCTTAGCGCCTATCGTAGCCTCACC
CTTTTAACCAATCCGGATTCTGTGCGTTTTGGCTGGGCCAACAAGCATATTATCAAGAACGTGAAACGCGACGATATTCT
GGCTCAATTGGAAAAAAGCCTGAAGGCCGGACGCGCGGTGCCGCCCCATAATCGCGAACAATGGGCCGAGCTGGTTAGCC
GTGAGATCGACGATGTCAGTCGCCTGCCGCAGCAGACGGTGCTGAAAATCAAACGGCCGGTAAAAGTGCAACCCATCGCC
CGGGTGTGGTATCAGCCGCAGCAAAAACAGGTGCAACACCCATGCCCGCTGCCGTTGATTGCCCTGTGCCAGCTAGAAAA
CGGTGCTCAGGTGCCAAAAATTGGCGAATTGCTCAATTACGACGCCGCGGCGGTCAAACATAAATACAAACCCGATGCCA
GACCGCTGCGGCTGCTGGTCAAACGACTGCATTTATATACCGACGTTCCCGATCGCTGA

Upstream 100 bases:

>100_bases
CAGGCTGGACCACTCGGTACCCCTGCTCACACTGTTGCCGATGTTGCCCTTTCGTTTGCTACTCTTTTATTGTATGTTGT
AACTAAAATGGGAGTGCGTG

Downstream 100 bases:

>100_bases
GGCTGCACACTCGCAGACGATGACCATCCGGCTCCAGGCATTTCTCTCAATAAAAAAGGCTTACCTCAAGTAAGCCCTTT
GCCACTGGTGCTATCGATTA

Product: DNA replication terminus site-binding protein

Products: NA

Alternate protein names: Ter-binding protein [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDKYDLIGRMNACFSELEQALTGLHQQILPLRLLAGRVFSLPEIEKGKEHDAVAQIAVEQHVGLAARDLALEHYQRLFIH
HNKHNISSKAAVRLPGVICLAVEQPDFLALQQQIALINRLKAELEQIITVDSGLAPEQRFDFVHTHLHGLITLSAYRSLT
LLTNPDSVRFGWANKHIIKNVKRDDILAQLEKSLKAGRAVPPHNREQWAELVSREIDDVSRLPQQTVLKIKRPVKVQPIA
RVWYQPQQKQVQHPCPLPLIALCQLENGAQVPKIGELLNYDAAAVKHKYKPDARPLRLLVKRLHLYTDVPDR

Sequences:

>Translated_312_residues
MDKYDLIGRMNACFSELEQALTGLHQQILPLRLLAGRVFSLPEIEKGKEHDAVAQIAVEQHVGLAARDLALEHYQRLFIH
HNKHNISSKAAVRLPGVICLAVEQPDFLALQQQIALINRLKAELEQIITVDSGLAPEQRFDFVHTHLHGLITLSAYRSLT
LLTNPDSVRFGWANKHIIKNVKRDDILAQLEKSLKAGRAVPPHNREQWAELVSREIDDVSRLPQQTVLKIKRPVKVQPIA
RVWYQPQQKQVQHPCPLPLIALCQLENGAQVPKIGELLNYDAAAVKHKYKPDARPLRLLVKRLHLYTDVPDR
>Mature_312_residues
MDKYDLIGRMNACFSELEQALTGLHQQILPLRLLAGRVFSLPEIEKGKEHDAVAQIAVEQHVGLAARDLALEHYQRLFIH
HNKHNISSKAAVRLPGVICLAVEQPDFLALQQQIALINRLKAELEQIITVDSGLAPEQRFDFVHTHLHGLITLSAYRSLT
LLTNPDSVRFGWANKHIIKNVKRDDILAQLEKSLKAGRAVPPHNREQWAELVSREIDDVSRLPQQTVLKIKRPVKVQPIA
RVWYQPQQKQVQHPCPLPLIALCQLENGAQVPKIGELLNYDAAAVKHKYKPDARPLRLLVKRLHLYTDVPDR

Specific function: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tus family [H]

Homologues:

Organism=Escherichia coli, GI1787895, Length=307, Percent_Identity=56.3517915309446, Blast_Score=349, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008865 [H]

Pfam domain/function: PF05472 Ter [H]

EC number: NA

Molecular weight: Translated: 35458; Mature: 35458

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYDLIGRMNACFSELEQALTGLHQQILPLRLLAGRVFSLPEIEKGKEHDAVAQIAVEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
HVGLAARDLALEHYQRLFIHHNKHNISSKAAVRLPGVICLAVEQPDFLALQQQIALINRL
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCEEEEEECCCHHHHHHHHHHHHHHH
KAELEQIITVDSGLAPEQRFDFVHTHLHGLITLSAYRSLTLLTNPDSVRFGWANKHIIKN
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEECCCCHHHHHH
VKRDDILAQLEKSLKAGRAVPPHNREQWAELVSREIDDVSRLPQQTVLKIKRPVKVQPIA
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHH
RVWYQPQQKQVQHPCPLPLIALCQLENGAQVPKIGELLNYDAAAVKHKYKPDARPLRLLV
HHHCCCCHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHH
KRLHLYTDVPDR
HHHHHHCCCCCC
>Mature Secondary Structure
MDKYDLIGRMNACFSELEQALTGLHQQILPLRLLAGRVFSLPEIEKGKEHDAVAQIAVEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
HVGLAARDLALEHYQRLFIHHNKHNISSKAAVRLPGVICLAVEQPDFLALQQQIALINRL
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCEEEEEECCCHHHHHHHHHHHHHHH
KAELEQIITVDSGLAPEQRFDFVHTHLHGLITLSAYRSLTLLTNPDSVRFGWANKHIIKN
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEECCCCHHHHHH
VKRDDILAQLEKSLKAGRAVPPHNREQWAELVSREIDDVSRLPQQTVLKIKRPVKVQPIA
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHH
RVWYQPQQKQVQHPCPLPLIALCQLENGAQVPKIGELLNYDAAAVKHKYKPDARPLRLLV
HHHCCCCHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHH
KRLHLYTDVPDR
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA