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The map label for this gene is pdxY [H]

Identifier: 157370460

GI number: 157370460

Start: 2420969

End: 2421829

Strand: Direct

Name: pdxY [H]

Synonym: Spro_2220

Alternate gene names: 157370460

Gene position: 2420969-2421829 (Clockwise)

Preceding gene: 157370459

Following gene: 157370465

Centisome position: 44.43

GC content: 56.45

Gene sequence:

>861_bases
ATGAAAAACATTCTTTCTATTCAATCCCATGTGGTGTTTGGCCATGCAGGCAACAGCGCGGCAGAGTTTCCGATGCGCCG
CATGGGCGTTAACGTCTGGTCGCTGAACACCGTGCAATTTTCCAATCATACTCAGTACGGCAAGTGGACCGGTTGCGTGA
TGCCGGCCAGCCATCTGACCGAGATTGCCCAGGGTATTGCGGATATAGATCAACTCAAGCACTGCGATGCGGTGCTGAGC
GGTTATATCGGTTCGCCGGAGCAGGGCAACCATATTCTTGAGATTGTGCGTCAGGTTAAGCAGGCCAATCCGAACGCCTG
GTATTTCTGCGATCCGGTGATGGGTCATCCGGAAAAAGGTTGCATCGTGGCACCGGGCGTGGCGGAGTTTCATTGTCAGC
AGGCGTTGCCGTGCAGTGACATGATTGCGCCCAATCTGCTGGAGCTGGAATTGCTGAGCCAGCGTACTGTGACCAACGTG
GAGCAGGCGGTAAGCGCCGCACGCGAGCTGATTGCCAAAGGGCCGAAGCTGGTGCTGGTCAAGCATCTGAGCCGTGCCGG
TTATAATATCGACTGTTTCGAAATGTTGCTGATCACGGCTAGTCAGGCCTGGCACATCAGCCGTCCGCTGGTGGACTTCG
GCGAGCGTCAACCGGTGGGTGTAGGCGACCTGACCAGTGGTCTGTTGCTGGTTAATTTGCTCAAGGGTGAGGCGTTGGAC
AAAGCACTCGAGCACGTCACGGCGGCGGTGTATGAAGTGATGCTGACGACCCAGGCGATGGGTGAGTATGAGCTGCAGGT
GGTGGCGGCTCAGGAGCGTATTGTGCAGCCGGGCTGCGAGTTTAAAGCGGTCATGCTGTAA

Upstream 100 bases:

>100_bases
GCAAAAAACATTACTGCCTGGTTGATTGGCAGTAAACAAAGTTGCAGCAAAGGGGCCCTCAGCGGCCCCTTTATTTTTAA
GGCCTCAGAGCAGGTTTTTG

Downstream 100 bases:

>100_bases
CGCTGCCGGCAGAGCGCCCCGGCGTATTCTCGCCGCCGGGGCGCAGGTATTATTTCAAGCCTTCCGCATTCAACGTTGCG
TCCACCGCAGGTCGCGCGGC

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWSLNTVQFSNHTQYGKWTGCVMPASHLTEIAQGIADIDQLKHCDAVLS
GYIGSPEQGNHILEIVRQVKQANPNAWYFCDPVMGHPEKGCIVAPGVAEFHCQQALPCSDMIAPNLLELELLSQRTVTNV
EQAVSAARELIAKGPKLVLVKHLSRAGYNIDCFEMLLITASQAWHISRPLVDFGERQPVGVGDLTSGLLLVNLLKGEALD
KALEHVTAAVYEVMLTTQAMGEYELQVVAAQERIVQPGCEFKAVML

Sequences:

>Translated_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWSLNTVQFSNHTQYGKWTGCVMPASHLTEIAQGIADIDQLKHCDAVLS
GYIGSPEQGNHILEIVRQVKQANPNAWYFCDPVMGHPEKGCIVAPGVAEFHCQQALPCSDMIAPNLLELELLSQRTVTNV
EQAVSAARELIAKGPKLVLVKHLSRAGYNIDCFEMLLITASQAWHISRPLVDFGERQPVGVGDLTSGLLLVNLLKGEALD
KALEHVTAAVYEVMLTTQAMGEYELQVVAAQERIVQPGCEFKAVML
>Mature_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWSLNTVQFSNHTQYGKWTGCVMPASHLTEIAQGIADIDQLKHCDAVLS
GYIGSPEQGNHILEIVRQVKQANPNAWYFCDPVMGHPEKGCIVAPGVAEFHCQQALPCSDMIAPNLLELELLSQRTVTNV
EQAVSAARELIAKGPKLVLVKHLSRAGYNIDCFEMLLITASQAWHISRPLVDFGERQPVGVGDLTSGLLLVNLLKGEALD
KALEHVTAAVYEVMLTTQAMGEYELQVVAAQERIVQPGCEFKAVML

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=180, Percent_Identity=36.6666666666667, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1787924, Length=286, Percent_Identity=77.6223776223776, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788758, Length=263, Percent_Identity=31.1787072243346, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17507759, Length=292, Percent_Identity=29.7945205479452, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=302, Percent_Identity=29.1390728476821, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320806, Length=239, Percent_Identity=30.9623430962343, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324354, Length=244, Percent_Identity=31.9672131147541, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45553007, Length=301, Percent_Identity=31.2292358803987, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31283; Mature: 31283

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWSLNTVQFSNHTQYGKWTGCVMPASHLT
CCCHHEEHHEEEEEECCCCHHHCCHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHH
EIAQGIADIDQLKHCDAVLSGYIGSPEQGNHILEIVRQVKQANPNAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFHCQQALPCSDMIAPNLLELELLSQRTVTNVEQAVSAARELIAKGPKLVLV
CEECCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
KHLSRAGYNIDCFEMLLITASQAWHISRPLVDFGERQPVGVGDLTSGLLLVNLLKGEALD
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KALEHVTAAVYEVMLTTQAMGEYELQVVAAQERIVQPGCEFKAVML
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWSLNTVQFSNHTQYGKWTGCVMPASHLT
CCCHHEEHHEEEEEECCCCHHHCCHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHH
EIAQGIADIDQLKHCDAVLSGYIGSPEQGNHILEIVRQVKQANPNAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFHCQQALPCSDMIAPNLLELELLSQRTVTNVEQAVSAARELIAKGPKLVLV
CEECCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
KHLSRAGYNIDCFEMLLITASQAWHISRPLVDFGERQPVGVGDLTSGLLLVNLLKGEALD
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KALEHVTAAVYEVMLTTQAMGEYELQVVAAQERIVQPGCEFKAVML
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA