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The map label for this gene is nemR [H]

Identifier: 157370443

GI number: 157370443

Start: 2404447

End: 2405067

Strand: Reverse

Name: nemR [H]

Synonym: Spro_2203

Alternate gene names: 157370443

Gene position: 2405067-2404447 (Counterclockwise)

Preceding gene: 157370444

Following gene: 157370442

Centisome position: 44.14

GC content: 58.94

Gene sequence:

>621_bases
ATGCTGACACCCATTATGACTAAACATGCGCACTGCCCTACAGATACCCGTGAACATTTGCTCGCTACCGGCGAGACCCT
CAGCCTGCGCCTCGGTTTTACCGGCATGGGGCTGAGCGAACTGCTGAGCACGGCGGGCGTGCCAAAAGGCTCGTTCTACC
ACTACTTCCGGTCGAAGGAAGTGTTTGGCGAAGCGATGCTGCAGCGCTATTTCGAACACTATGATGCGGCAATGCAGCAG
CTGTTTGCCGACGATAAAGGTGATGCACGCCACCAATTGTTGAGCTATTACGCTCAGGCGATCAGCTACCACTGCCGCAG
CGAATGCCATAACGCCTGCCTGGCGGTGAAATTGTCTGCCGAGGTGAGCGACCTGTCGGAACCCATGCGTCATGCGCTGG
AAACCGGCAGTGCCCGGGTGATTGGTCACCTGCAGGATACGATCGAACGCGGGATCCGCGAAGGTTCATTGTCGCTGGCC
ATGAGCCCGGCGGCCACGGCGGAAACGCTGTACTCCCTGTGGCTTGGCGCCTCTTTACGCGCCAAAATCCGCCACTCGGT
CGCCCCGCTGACCAGCGCGTTGGAAAGTATTGAACTGTTGTTGCGTCCGGCGCAGCGCTAA

Upstream 100 bases:

>100_bases
CTTAACTTCCGCACTTTATTCAGGCAAAGTATCACTCATCGTAACCGGCATTTTTATGCCGGTTTTTTTATTGTTATTGA
CCTAGACCAATCGGTCTATT

Downstream 100 bases:

>100_bases
AAAAAACCTGATTTATCATGAACTACCGCATTGGGCGGTTTTACATTCGTTACTAGTCGACCAGTCTATTAATATAGGAT
GCACTATGAAGATTGAAAAA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLTPIMTKHAHCPTDTREHLLATGETLSLRLGFTGMGLSELLSTAGVPKGSFYHYFRSKEVFGEAMLQRYFEHYDAAMQQ
LFADDKGDARHQLLSYYAQAISYHCRSECHNACLAVKLSAEVSDLSEPMRHALETGSARVIGHLQDTIERGIREGSLSLA
MSPAATAETLYSLWLGASLRAKIRHSVAPLTSALESIELLLRPAQR

Sequences:

>Translated_206_residues
MLTPIMTKHAHCPTDTREHLLATGETLSLRLGFTGMGLSELLSTAGVPKGSFYHYFRSKEVFGEAMLQRYFEHYDAAMQQ
LFADDKGDARHQLLSYYAQAISYHCRSECHNACLAVKLSAEVSDLSEPMRHALETGSARVIGHLQDTIERGIREGSLSLA
MSPAATAETLYSLWLGASLRAKIRHSVAPLTSALESIELLLRPAQR
>Mature_206_residues
MLTPIMTKHAHCPTDTREHLLATGETLSLRLGFTGMGLSELLSTAGVPKGSFYHYFRSKEVFGEAMLQRYFEHYDAAMQQ
LFADDKGDARHQLLSYYAQAISYHCRSECHNACLAVKLSAEVSDLSEPMRHALETGSARVIGHLQDTIERGIREGSLSLA
MSPAATAETLYSLWLGASLRAKIRHSVAPLTSALESIELLLRPAQR

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=193, Percent_Identity=50.259067357513, Blast_Score=190, Evalue=5e-50,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22793; Mature: 22793

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPIMTKHAHCPTDTREHLLATGETLSLRLGFTGMGLSELLSTAGVPKGSFYHYFRSKE
CCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHH
VFGEAMLQRYFEHYDAAMQQLFADDKGDARHQLLSYYAQAISYHCRSECHNACLAVKLSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECH
EVSDLSEPMRHALETGSARVIGHLQDTIERGIREGSLSLAMSPAATAETLYSLWLGASLR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHCHHHH
AKIRHSVAPLTSALESIELLLRPAQR
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTPIMTKHAHCPTDTREHLLATGETLSLRLGFTGMGLSELLSTAGVPKGSFYHYFRSKE
CCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHH
VFGEAMLQRYFEHYDAAMQQLFADDKGDARHQLLSYYAQAISYHCRSECHNACLAVKLSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECH
EVSDLSEPMRHALETGSARVIGHLQDTIERGIREGSLSLAMSPAATAETLYSLWLGASLR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHCHHHH
AKIRHSVAPLTSALESIELLLRPAQR
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]