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The map label for this gene is idi

Identifier: 157370441

GI number: 157370441

Start: 2402654

End: 2403193

Strand: Direct

Name: idi

Synonym: Spro_2201

Alternate gene names: 157370441

Gene position: 2402654-2403193 (Clockwise)

Preceding gene: 157370438

Following gene: 157370446

Centisome position: 44.09

GC content: 51.85

Gene sequence:

>540_bases
ATGGATGAAATGCTAATTCTGGTGGATGCTGATGATAATGCCATTGGCTCCCAAAGCAAAACGCGGGTACACCAACAGGG
GTTACTGCACCGGGCATTTTCAATTTTTATCTTTGATAGCCAGGGCCGCCTGCTGTTGCAACAGCGGGCATTCAGTAAGT
ATCACTCGGCCGGGCTATGGACCAACAGTTGCTGTGGCCACCCGCGCTGGGGTGAGTCAACGCTGGCCGCGGCTCAGCGC
CGCCTGCAGGAAGAGATGGGGTTCAGCGCTGAGCTACAACAAGTTTCCAGTTTTACCTATCAGGCTGCGGTACCCGGCGA
TTTAATTGAGCACGAATTCGATCATATCTACGTCGGTTTATTTGACGGCAAGCCGCAGGGGGCGCCTGAAGAGGCCCATA
GTTGGTCGTGGACTGATATTCAGCAATTAACGGATGAAACAACGCGCAATCCTGAAAAGTTTACCGTTTGGTTTCTCACG
ATAATGAAGGATCTTGGCGCCAATGAAATGGAACGTTGGGCAAGGTTGGCTGCGAGTTAA

Upstream 100 bases:

>100_bases
TGTTGCGTCCGGATTGGGCGGGATTAATTTATAAATTTGGATCTGGTTAATATGACTTTTTTCAGTACGAGAACATCGCG
TTTGCCGAAGGAGCCGATCA

Downstream 100 bases:

>100_bases
CTGACAGGTTTCCCCCTAAATGGCAAAAAGCCCGCCGGCATTGGCATACCGGCGGGCTTTGCTGTTTTACTTACAGCGTT
GGGTAGTCGGTGTAGCCTTC

Product: isopentenyl-diphosphate delta-isomerase, type 1

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLWTNSCCGHPRWGESTLAAAQR
RLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGLFDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLT
IMKDLGANEMERWARLAAS

Sequences:

>Translated_179_residues
MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLWTNSCCGHPRWGESTLAAAQR
RLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGLFDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLT
IMKDLGANEMERWARLAAS
>Mature_179_residues
MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLWTNSCCGHPRWGESTLAAAQR
RLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGLFDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLT
IMKDLGANEMERWARLAAS

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI40018633, Length=184, Percent_Identity=33.695652173913, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI15147242, Length=186, Percent_Identity=32.7956989247312, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI1789255, Length=160, Percent_Identity=31.25, Blast_Score=87, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17554092, Length=132, Percent_Identity=35.6060606060606, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325140, Length=194, Percent_Identity=33.5051546391753, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362205, Length=185, Percent_Identity=33.5135135135135, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648688, Length=185, Percent_Identity=33.5135135135135, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_SERP5 (A8GDW2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478430.1
- ProteinModelPortal:   A8GDW2
- SMR:   A8GDW2
- STRING:   A8GDW2
- GeneID:   5605483
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2201
- eggNOG:   COG1443
- HOGENOM:   HBG416977
- OMA:   RTHEELG
- ProtClustDB:   CLSK923536
- BioCyc:   SPRO399741:SPRO_2201-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 20349; Mature: 20349

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 65-65 ACT_SITE 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLW
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCC
TNSCCGHPRWGESTLAAAQRRLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEE
FDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLTIMKDLGANEMERWARLAAS
ECCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MDEMLILVDADDNAIGSQSKTRVHQQGLLHRAFSIFIFDSQGRLLLQQRAFSKYHSAGLW
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCC
TNSCCGHPRWGESTLAAAQRRLQEEMGFSAELQQVSSFTYQAAVPGDLIEHEFDHIYVGL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEE
FDGKPQGAPEEAHSWSWTDIQQLTDETTRNPEKFTVWFLTIMKDLGANEMERWARLAAS
ECCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA