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The map label for this gene is arnT

Identifier: 157370398

GI number: 157370398

Start: 2355154

End: 2356821

Strand: Direct

Name: arnT

Synonym: Spro_2158

Alternate gene names: 157370398

Gene position: 2355154-2356821 (Clockwise)

Preceding gene: 157370397

Following gene: 157370399

Centisome position: 43.22

GC content: 55.64

Gene sequence:

>1668_bases
ATGAAGGCGCTAAAAGGATCATGGGCTATTTTGTTGGCCATTTTTTTTGCTCTGGTTTACCTGATTCCGCTCAACGGCCG
CCTGCTATGGCAACCGGATGAAACCCGCTACGCCGAGATTAGCCGCGAAATGCTGCAACGCGGCGACTGGGTAGTGCCAC
ATTTGCTTGGCCTGCGTTATTTTGAAAAACCGGTGGCCGGCTACTGGTTCAATAACATCAGCCAATGGTTGTTTGGCGAT
ACCAACTTTGCGGTGCGCTTCGGTTCGGTATTCAGTACCGGCATGACGGCGCTGCTGGTATTCGCACTGGCAATGCTGAT
GTGGCGCAATGCGCGCCGTGCCAGCCTGGCGACGTTGATTTTCCTGTCGATGGTTCTGGTATTCAGTATCGGTACCTACA
GCGTGTTGGACCCGATGATCTCCTTGTGGCTGGCCGCCGCGATGGTCAGTTATTATCTGACGCTGAAAGCGACCACGGCC
AAAGGCAAGCTGGGCGGCTACGTGCTGTTGGGGCTGGCCTGCGGCATGGGCTTTATGACCAAGGGCTTCCTGGCACTGGC
GGTGCCGGTGATCGCGGTGATCCCGATTGTCATTCAACAGCGGCGAATTAAAGATCTGCTGATCTACGGCCCAGTGGCTA
TCGTAGTGGCGGTGCTGCTGAGCTTGCCTTGGGCGCTGGCCATCGCACAACGTGAGCCGGATTTCTGGAACTACTTCTTC
TGGGTGGAGCATATTCAACGTTTCGCCGAGGACAACGCGCAACATAAAGCCCCGTTCTGGTATTACGTCCCGGTTTTGAT
GGCGGCGGTGTTGCCCTGGTTGGCGCTACTGCCGGGCTCCTTGCTCAAGGGCTGGCGGGAACGCGTTCAGCGTCCGGAAC
TGTTCTTCCTGCTTAGCTGGGTAATGATGCCGTTGATCTTCTTCAGCATCGCCAAGGGCAAGCTGCCGACCTATATTTTA
CCGTGCATGGCACCCCTGGCATTGCTGATGGCAGCCTATGCTGAAGACTGCGTGGCGGCATTGCGCAGCAAGGTATTCAA
GGTTAACGCCGTATTAAACGGATTGTTTGGCTTAATCTGCATCCTGGCGCTGGTGGTTCTGGGCTCCGGACTGTTACCCA
AAGTGCATTTGTTTACCGCGCAAGAGTGGCCGAAGATTGTTATCGGCATTATCGCCTTTGCCGGTTGGTTGTTGTTTGCC
GTAGTGTCGGTGCGTAATAATGCGCAACGCTGGAGCTGGGCAGCGGCTTGCCCATTGTTGCTGTGTTTGTTGATTGGTTA
CGCCATTCCGCAGCAGGTGACCGACTCCAAGCTGCCGCAAAACTTTATCCGGGTGAATATGGCTGAGTTAGGCCATAGCC
GCTACGTGCTGACCGACAGCGTTGGCGTAGCGGCTGGGTTGGCCTGGGAGTTGAAGCGCAGCGACGTATTGATGTTTAAC
CAGAAGGGGGAGGTGTCCTACGGTTTGGAGTATCCGGATGCCCGCAGCCATCTCATCAGCGACAGCGATTTCCCGCAGTG
GCTGGCACAGGCGCGCAAGCAGGGCGATGTCTCACTGGTGTTGCAGTTGTCGCGTGGAGAAAGCATTGATCAGCAAAAGC
TGCCGAAAGCAGATAAGGTTGAGGTGATGAATCGTCTGGCGTTGTTCTGGTACCAACAGCAGCCATGA

Upstream 100 bases:

>100_bases
CTCAAGATTTGGCGTCATTGCCATTGGGCCGCGTCGAGCGCGCTCCTTTCCCTGGCCGCGAAGGTTGGCTGGGTTGTCAA
ACCGATGTGAAGGACGATTC

Downstream 100 bases:

>100_bases
TAGTCGGCTATTTGTTGGTGGTACTGGTCAGTCTGCTCACCTGTGGTGGGCAGCTGTGCCAGAAACAGGCCGCTCTGAGC
TGGCAGTTACCTCCCGAAGT

Product: 4-amino-4-deoxy-L-arabinose transferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRYFEKPVAGYWFNNISQWLFGD
TNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLIFLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTA
KGKLGGYVLLGLACGMGFMTKGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSWVMMPLIFFSIAKGKLPTYIL
PCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLICILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFA
VVSVRNNAQRWSWAAACPLLLCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFN
QKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKVEVMNRLALFWYQQQP

Sequences:

>Translated_555_residues
MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRYFEKPVAGYWFNNISQWLFGD
TNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLIFLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTA
KGKLGGYVLLGLACGMGFMTKGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSWVMMPLIFFSIAKGKLPTYIL
PCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLICILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFA
VVSVRNNAQRWSWAAACPLLLCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFN
QKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKVEVMNRLALFWYQQQP
>Mature_555_residues
MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRYFEKPVAGYWFNNISQWLFGD
TNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLIFLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTA
KGKLGGYVLLGLACGMGFMTKGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSWVMMPLIFFSIAKGKLPTYIL
PCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLICILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFA
VVSVRNNAQRWSWAAACPLLLCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFN
QKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKVEVMNRLALFWYQQQP

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family

Homologues:

Organism=Escherichia coli, GI1788591, Length=555, Percent_Identity=52.972972972973, Blast_Score=588, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNT_SERP5 (A8GDR9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478387.1
- STRING:   A8GDR9
- GeneID:   5605898
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2158
- eggNOG:   COG1807
- HOGENOM:   HBG298640
- OMA:   ASMAFES
- ProtClustDB:   PRK13279
- BioCyc:   SPRO399741:SPRO_2158-MONOMER
- HAMAP:   MF_01165
- InterPro:   IPR022839
- InterPro:   IPR003342

Pfam domain/function: PF02366 PMT

EC number: =2.4.2.43

Molecular weight: Translated: 62363; Mature: 62363

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x247f9a20)-; HASH(0x24de6ef0)-; HASH(0x40548244)-; HASH(0x24ada2c4)-; HASH(0x405407f8)-; HASH(0x24e4aa5c)-; HASH(0x25495590)-; HASH(0x25183610)-; HASH(0x25160600)-; HASH(0x2524a3dc)-; HASH(0x24eb6eb4)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRY
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEKPVAGYWFNNISQWLFGDTNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLI
HHCCHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTAKGKLGGYVLLGLACGMGFMT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCHHHHH
KGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHCCCCCHHHHHH
WVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSW
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
VMMPLIFFSIAKGKLPTYILPCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLIC
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFAVVSVRNNAQRWSWAAACPLL
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFN
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHEECCCCEEEEE
QKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKV
CCCCEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHCCCCHHH
EVMNRLALFWYQQQP
HHHHHHHHHHCCCCH
>Mature Secondary Structure
MKALKGSWAILLAIFFALVYLIPLNGRLLWQPDETRYAEISREMLQRGDWVVPHLLGLRY
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEKPVAGYWFNNISQWLFGDTNFAVRFGSVFSTGMTALLVFALAMLMWRNARRASLATLI
HHCCHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FLSMVLVFSIGTYSVLDPMISLWLAAAMVSYYLTLKATTAKGKLGGYVLLGLACGMGFMT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCHHHHH
KGFLALAVPVIAVIPIVIQQRRIKDLLIYGPVAIVVAVLLSLPWALAIAQREPDFWNYFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHCCCCCHHHHHH
WVEHIQRFAEDNAQHKAPFWYYVPVLMAAVLPWLALLPGSLLKGWRERVQRPELFFLLSW
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
VMMPLIFFSIAKGKLPTYILPCMAPLALLMAAYAEDCVAALRSKVFKVNAVLNGLFGLIC
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILALVVLGSGLLPKVHLFTAQEWPKIVIGIIAFAGWLLFAVVSVRNNAQRWSWAAACPLL
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LCLLIGYAIPQQVTDSKLPQNFIRVNMAELGHSRYVLTDSVGVAAGLAWELKRSDVLMFN
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHEECCCCEEEEE
QKGEVSYGLEYPDARSHLISDSDFPQWLAQARKQGDVSLVLQLSRGESIDQQKLPKADKV
CCCCEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHCCCCHHH
EVMNRLALFWYQQQP
HHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA