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The map label for this gene is arnD

Identifier: 157370397

GI number: 157370397

Start: 2354252

End: 2355157

Strand: Direct

Name: arnD

Synonym: Spro_2157

Alternate gene names: 157370397

Gene position: 2354252-2355157 (Clockwise)

Preceding gene: 157370396

Following gene: 157370398

Centisome position: 43.21

GC content: 56.62

Gene sequence:

>906_bases
ATGAAGAAAGTCGGTCTGCGAGTTGACGTAGATACCTTCAGCGGCACCCGGGAAGGGGTGCCGCAGTTGCTGGAGCTGTT
CGACAAGTACAATATTCAGGCCAGTTTCTTCTTCAGCGTTGGACCGGACAATATGGGGCGCCATTTGTGGCGCCTTTTGC
GTCCGAAATTCCTGTGGAAAATGCTGCGCTCCAATGCCGCGTCACTGTACGGCTGGGATATTTTGCTGGCAGGCACGGCC
TGGCCGGGGCGTAATATTGCCCGTGCCCTGGGGCCGTTGATGAAACTGACTGCCCAGGCTGGGCATGAAGTGGGGCTGCA
CGCCTGGGATCACCAGGGTTGGCAGGCCAAGGTTGGCCGTTGGTCAGAAGCGCAACTGATGCAGCAGGTTCAGCTCGGTG
TGGATGCGCTGGCCAACAGTACCGGTCAGCCTGTCAAATGTTCGGCGGTTGCCGGTTGGCGTGCCGATACGCGGGTGCTG
GAAGTGAAGCAGCGTTTTGGTTTTCACTACAACAGCGACTGTCGTGGCACCCATCCCTTCCGTCCGGTGTTAAGCGATGG
CCGCCTGGGAACCGTACAAATCCCTGTCACGCTGCCTACCTTTGATGAGGTGATTGGCAGTGAAGTGAGTATGAATGATT
TCAACGATTACATTCTGCGGGAGATTGAAAACGATCGCGGTGTGCCGGTGTATACCATTCATACCGAAGTGGAGGGCATG
TCACAGGCCGCAATGTTTGAGCAGTTATTGCTGCGGGCGCAACGGCAGGGCATAGAATTCTGTCCGTTAAGCGCACTGTT
GCCTCAAGATTTGGCGTCATTGCCATTGGGCCGCGTCGAGCGCGCTCCTTTCCCTGGCCGCGAAGGTTGGCTGGGTTGTC
AAACCGATGTGAAGGACGATTCATGA

Upstream 100 bases:

>100_bases
GCCGCTTGCTGGATTGGCAGCCAACCATCGCCATGCAGCAAACCGTCGCTGATACGTTGGATTACTTCCTGCGTACGACC
GTTCAGGAAGGTGACGGTGC

Downstream 100 bases:

>100_bases
AGGCGCTAAAAGGATCATGGGCTATTTTGTTGGCCATTTTTTTTGCTCTGGTTTACCTGATTCCGCTCAACGGCCGCCTG
CTATGGCAACCGGATGAAAC

Product: polysaccharide deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKKVGLRVDVDTFSGTREGVPQLLELFDKYNIQASFFFSVGPDNMGRHLWRLLRPKFLWKMLRSNAASLYGWDILLAGTA
WPGRNIARALGPLMKLTAQAGHEVGLHAWDHQGWQAKVGRWSEAQLMQQVQLGVDALANSTGQPVKCSAVAGWRADTRVL
EVKQRFGFHYNSDCRGTHPFRPVLSDGRLGTVQIPVTLPTFDEVIGSEVSMNDFNDYILREIENDRGVPVYTIHTEVEGM
SQAAMFEQLLLRAQRQGIEFCPLSALLPQDLASLPLGRVERAPFPGREGWLGCQTDVKDDS

Sequences:

>Translated_301_residues
MKKVGLRVDVDTFSGTREGVPQLLELFDKYNIQASFFFSVGPDNMGRHLWRLLRPKFLWKMLRSNAASLYGWDILLAGTA
WPGRNIARALGPLMKLTAQAGHEVGLHAWDHQGWQAKVGRWSEAQLMQQVQLGVDALANSTGQPVKCSAVAGWRADTRVL
EVKQRFGFHYNSDCRGTHPFRPVLSDGRLGTVQIPVTLPTFDEVIGSEVSMNDFNDYILREIENDRGVPVYTIHTEVEGM
SQAAMFEQLLLRAQRQGIEFCPLSALLPQDLASLPLGRVERAPFPGREGWLGCQTDVKDDS
>Mature_301_residues
MKKVGLRVDVDTFSGTREGVPQLLELFDKYNIQASFFFSVGPDNMGRHLWRLLRPKFLWKMLRSNAASLYGWDILLAGTA
WPGRNIARALGPLMKLTAQAGHEVGLHAWDHQGWQAKVGRWSEAQLMQQVQLGVDALANSTGQPVKCSAVAGWRADTRVL
EVKQRFGFHYNSDCRGTHPFRPVLSDGRLGTVQIPVTLPTFDEVIGSEVSMNDFNDYILREIENDRGVPVYTIHTEVEGM
SQAAMFEQLLLRAQRQGIEFCPLSALLPQDLASLPLGRVERAPFPGREGWLGCQTDVKDDS

Specific function: Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial p

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily

Homologues:

Organism=Escherichia coli, GI1788590, Length=294, Percent_Identity=61.9047619047619, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARND_SERP5 (A8GDR8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478386.1
- STRING:   A8GDR8
- GeneID:   5605903
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2157
- eggNOG:   COG0726
- HOGENOM:   HBG298639
- OMA:   CSAVAGW
- ProtClustDB:   PRK15394
- BioCyc:   SPRO399741:SPRO_2157-MONOMER
- HAMAP:   MF_01870
- InterPro:   IPR011330
- InterPro:   IPR002509
- Gene3D:   G3DSA:3.20.20.370

Pfam domain/function: PF01522 Polysacc_deac_1; SSF88713 Glyco_hydro/deAcase_b/a-brl

EC number: NA

Molecular weight: Translated: 33692; Mature: 33692

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGLRVDVDTFSGTREGVPQLLELFDKYNIQASFFFSVGPDNMGRHLWRLLRPKFLWK
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
MLRSNAASLYGWDILLAGTAWPGRNIARALGPLMKLTAQAGHEVGLHAWDHQGWQAKVGR
HHHHCCCCEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHCCC
WSEAQLMQQVQLGVDALANSTGQPVKCSAVAGWRADTRVLEVKQRFGFHYNSDCRGTHPF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCC
RPVLSDGRLGTVQIPVTLPTFDEVIGSEVSMNDFNDYILREIENDRGVPVYTIHTEVEGM
CCCCCCCCEEEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCH
SQAAMFEQLLLRAQRQGIEFCPLSALLPQDLASLPLGRVERAPFPGREGWLGCQTDVKDD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCC
S
C
>Mature Secondary Structure
MKKVGLRVDVDTFSGTREGVPQLLELFDKYNIQASFFFSVGPDNMGRHLWRLLRPKFLWK
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
MLRSNAASLYGWDILLAGTAWPGRNIARALGPLMKLTAQAGHEVGLHAWDHQGWQAKVGR
HHHHCCCCEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHCCC
WSEAQLMQQVQLGVDALANSTGQPVKCSAVAGWRADTRVLEVKQRFGFHYNSDCRGTHPF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCC
RPVLSDGRLGTVQIPVTLPTFDEVIGSEVSMNDFNDYILREIENDRGVPVYTIHTEVEGM
CCCCCCCCEEEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCH
SQAAMFEQLLLRAQRQGIEFCPLSALLPQDLASLPLGRVERAPFPGREGWLGCQTDVKDD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA