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The map label for this gene is arnC

Identifier: 157370395

GI number: 157370395

Start: 2351293

End: 2352273

Strand: Direct

Name: arnC

Synonym: Spro_2155

Alternate gene names: 157370395

Gene position: 2351293-2352273 (Clockwise)

Preceding gene: 157370394

Following gene: 157370396

Centisome position: 43.15

GC content: 54.33

Gene sequence:

>981_bases
GTGTCTCGCGTTGAACCGATAAAAAAAGTTTCGGTGGTGATCCCGGTCTATAACGAGCAGGAAAGTTTGCCTGCCTTGCT
CGAACGTACCACCGCCGCCTGTAAACAACTGACCCAACCTTATGAAATTATCCTGGTCGATGACGGCAGCAGCGACAATT
CTGCCGATATGCTGACCGCCGCGGCCGAACAGCCGGGCAGCTGTGTGATTGCCGTGTTGCTTAACCGTAACTATGGGCAG
CATTCGGCGATCATGGCCGGTTTCAATCAGGTAAGTGGCGATCTGGTGATTACGCTGGATGCCGATTTGCAAAACCCGCC
GGAAGAGATCCCGCGTCTGGTGAAAGTGGCGGAGGAAGGTTACGACGTGGTGGGAACCGTACGTGCCAACCGTCAGGACT
CCTGGTTCCGCAAAAGCGCTTCGCGCATCATCAATATGATGATCCAACGTGCCACCGGTAAATCGATGGGGGATTACGGC
TGCATGCTGCGCGCCTATCGCCGCCATATTATCGAGGCGATGTTGAACTGCCACGAGCGCAGTACCTTTATCCCCATTCT
GGCGAATACCTTTGCCCGCCGCACCACTGAAATTGAAGTGCTGCATGCCGAGCGCGAGTTTGGTGATTCCAAATACAGCC
TGATGAAGCTGATTAACCTGATGTATGACCTGATCACCTGCCTGACCACGACGCCGCTGCGTTTGCTCAGCGTGGTGGGC
AGTGTGGTGGCGCTGTCAGGTTTTTTGCTGGCGGTGCTGTTGATCGCTTTGCGTTTGATTATGGGACCTGAATGGTCGGG
CGGCGGGGTGTTCACCCTGTTTGCCGTGCTGTTTACCTTTATCGGCGCCCAATTTGTCGGTATGGGCCTGTTGGGAGAGT
ACATCGGTCGCATCTATACCGACGTTCGTGCTCGTCCCCGTTATTTTGTTCAGAAAGTGGTCGGTGAACAGCCGAACCAC
AATACTCAGGAAGAAGAATAA

Upstream 100 bases:

>100_bases
AACTCGGCACGTCTGTGCACCTTGCCGCTATTCCCTGATATGACCGACGCCGATGTTGATCGCGTGGTTAAAGCCTTGTC
TTCTGTTGTGGAGTCGTTAC

Downstream 100 bases:

>100_bases
TGAAAGCTATCGTATTTGCTTACCATGATATTGGCTGCGCTGGTCTGAAAGCGCTGACTGACGCGGGCTATGATATTCAG
GCGGTATTCACCCATACCGA

Product: undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTAAAEQPGSCVIAVLLNRNYGQ
HSAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEGYDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYG
CMLRAYRRHIIEAMLNCHERSTFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVG
SVVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYTDVRARPRYFVQKVVGEQPNH
NTQEEE

Sequences:

>Translated_326_residues
MSRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTAAAEQPGSCVIAVLLNRNYGQ
HSAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEGYDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYG
CMLRAYRRHIIEAMLNCHERSTFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVG
SVVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYTDVRARPRYFVQKVVGEQPNH
NTQEEE
>Mature_325_residues
SRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTAAAEQPGSCVIAVLLNRNYGQH
SAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEGYDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYGC
MLRAYRRHIIEAMLNCHERSTFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVGS
VVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYTDVRARPRYFVQKVVGEQPNHN
TQEEE

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

Organism=Homo sapiens, GI4503363, Length=235, Percent_Identity=26.8085106382979, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788588, Length=321, Percent_Identity=74.1433021806854, Blast_Score=520, Evalue=1e-149,
Organism=Escherichia coli, GI1788692, Length=315, Percent_Identity=31.7460317460317, Blast_Score=171, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI71999402, Length=236, Percent_Identity=24.1525423728814, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325441, Length=179, Percent_Identity=29.0502793296089, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24585265, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNC_SERP5 (A8GDR6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478384.1
- ProteinModelPortal:   A8GDR6
- SMR:   A8GDR6
- STRING:   A8GDR6
- GeneID:   5605901
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2155
- eggNOG:   COG0463
- HOGENOM:   HBG752660
- OMA:   ITRITMT
- ProtClustDB:   PRK10714
- BioCyc:   SPRO399741:SPRO_2155-MONOMER
- HAMAP:   MF_01164
- InterPro:   IPR022857
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: =2.7.8.30

Molecular weight: Translated: 36227; Mature: 36096

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x25497718)-; HASH(0x253b136c)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTA
CCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
AAEQPGSCVIAVLLNRNYGQHSAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEG
HCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYGCMLRAYRRHIIEAMLNCHER
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
STFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVG
CCHHHHHHHHHHHHCCHHEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQKVVGEQPNHNTQEEE
HHHCCHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
SRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTA
CCCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
AAEQPGSCVIAVLLNRNYGQHSAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEG
HCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYGCMLRAYRRHIIEAMLNCHER
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
STFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVG
CCHHHHHHHHHHHHCCHHEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQKVVGEQPNHNTQEEE
HHHCCHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA