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The map label for this gene is marC [H]

Identifier: 157370381

GI number: 157370381

Start: 2337567

End: 2338256

Strand: Reverse

Name: marC [H]

Synonym: Spro_2141

Alternate gene names: 157370381

Gene position: 2338256-2337567 (Counterclockwise)

Preceding gene: 157370382

Following gene: 157370374

Centisome position: 42.91

GC content: 55.51

Gene sequence:

>690_bases
ATGACGAGTATTCTGCAGTTATTCCAGGCCATTGGGCTGGGTTTGGTGCTACTGCTGCCCCTGGCCAACCCACTCACCAC
GGTCGCGCTGTTGCTCGGTCTTTCGGGCAATATGACGCGCGAAGAGCGCAACCAGCAATCGCTGATGGCATCGGTCTATG
TGTTCTTTATCATGACGGTGGCGTTCTATGCCGGCCAGTTGGTCATGAACACCTTTGGCATCTCTATTCCCGGTTTGCGG
ATCGCCGGCGGGCTGATTGTGGCGTTTATTGGCTTTCGCATGCTGTTCCCGCAGCAAAGTGCGGACGAAGCTCCAGAGGT
TGAGAGCAAAAGCAAAGAGCTGCGCAAAAAAACCTCGGCCAATATCGCCTTTGTGCCACTGGCGATGCCCAGCACCGCCG
GTCCGGGTACCATTGCGATGATCATCAGCTCGGCATCGAGCGTCAAAGAGAACACCCTGGGATTTGCACACTGGGTGTTG
CTGGTTGCGCCAGTGGCCATCTTCCTGTCGGTAGCCCTGATTTTATGGGCTTGCCTGCGCAGCTCTGGCGCCATTATGAG
GCTGGTGGGTCAAAGTGGCATTGAGGCGATCTCACGCCTGATGGGTTTCCTGCTGGTGTGTATGGGCGTGCAATTTATTA
TCAACGGCATATTGGAGATCATCTCAACCTATACCCCAGCCGTTGCCTGA

Upstream 100 bases:

>100_bases
TTACAGCTCGCTTCCCTGGCGTTGCCGCTGAGCGTGCGGCAAGTTAGGGTATGACTTTATGCTGCGTCACAACATTCACT
GAAAACAGGAAGTCTGACCC

Downstream 100 bases:

>100_bases
CCCATGAATACGGGCGCAACATGCGCCCGCTTCACTTACTTACCTGTTGGCGCCTGCGCGCCTAAAATGCCCTTGCCTTC
CGGCACTTCGGTAAAACGAC

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTSILQLFQAIGLGLVLLLPLANPLTTVALLLGLSGNMTREERNQQSLMASVYVFFIMTVAFYAGQLVMNTFGISIPGLR
IAGGLIVAFIGFRMLFPQQSADEAPEVESKSKELRKKTSANIAFVPLAMPSTAGPGTIAMIISSASSVKENTLGFAHWVL
LVAPVAIFLSVALILWACLRSSGAIMRLVGQSGIEAISRLMGFLLVCMGVQFIINGILEIISTYTPAVA

Sequences:

>Translated_229_residues
MTSILQLFQAIGLGLVLLLPLANPLTTVALLLGLSGNMTREERNQQSLMASVYVFFIMTVAFYAGQLVMNTFGISIPGLR
IAGGLIVAFIGFRMLFPQQSADEAPEVESKSKELRKKTSANIAFVPLAMPSTAGPGTIAMIISSASSVKENTLGFAHWVL
LVAPVAIFLSVALILWACLRSSGAIMRLVGQSGIEAISRLMGFLLVCMGVQFIINGILEIISTYTPAVA
>Mature_228_residues
TSILQLFQAIGLGLVLLLPLANPLTTVALLLGLSGNMTREERNQQSLMASVYVFFIMTVAFYAGQLVMNTFGISIPGLRI
AGGLIVAFIGFRMLFPQQSADEAPEVESKSKELRKKTSANIAFVPLAMPSTAGPGTIAMIISSASSVKENTLGFAHWVLL
VAPVAIFLSVALILWACLRSSGAIMRLVGQSGIEAISRLMGFLLVCMGVQFIINGILEIISTYTPAVA

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=80.0904977375566, Blast_Score=327, Evalue=4e-91,
Organism=Escherichia coli, GI1787494, Length=200, Percent_Identity=31.5, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1789842, Length=204, Percent_Identity=26.9607843137255, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 24382; Mature: 24250

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSILQLFQAIGLGLVLLLPLANPLTTVALLLGLSGNMTREERNQQSLMASVYVFFIMTV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AFYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQSADEAPEVESKSKELRKKTSA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
NIAFVPLAMPSTAGPGTIAMIISSASSVKENTLGFAHWVLLVAPVAIFLSVALILWACLR
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGAIMRLVGQSGIEAISRLMGFLLVCMGVQFIINGILEIISTYTPAVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSILQLFQAIGLGLVLLLPLANPLTTVALLLGLSGNMTREERNQQSLMASVYVFFIMTV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AFYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQSADEAPEVESKSKELRKKTSA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
NIAFVPLAMPSTAGPGTIAMIISSASSVKENTLGFAHWVLLVAPVAIFLSVALILWACLR
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGAIMRLVGQSGIEAISRLMGFLLVCMGVQFIINGILEIISTYTPAVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA