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The map label for this gene is yfeD [H]

Identifier: 157370370

GI number: 157370370

Start: 2325802

End: 2326662

Strand: Reverse

Name: yfeD [H]

Synonym: Spro_2130

Alternate gene names: 157370370

Gene position: 2326662-2325802 (Counterclockwise)

Preceding gene: 157370371

Following gene: 157370368

Centisome position: 42.7

GC content: 55.52

Gene sequence:

>861_bases
ATGGAAACTCTGTATCAACTGCTCAGCGAACCGTTCGCCTATCCGTTTATGCAACGGGCGATCCTGGCCGCTATCGTCAC
TGGCGTAGTCTGTGCGGTACTGTCCTGTTATCTGGTGCTCAAGGGCTGGTCGCTGATGGGCGATGCCATTTCGCATGCGG
TGCTGCCCGGCATCGTGCTGGCGTTCGTGCTCGGTATCCCGGTGGTGATCGGCGCGTTTTTCTCCGGTATTTTCTGCGCG
GTCGCCACCGGATATCTGAAAGAAAACAGCCGGGTGAAAGAGGATACGGTGATGGGCATCGTGTTCTCTGGCATGTTCGC
CTTCGGGCTGGTGTTGTTTTCGCGCGTCGATACCGATCAGCATCTGAGCCACATTCTGTTCGGCAATATGCTGGGCATTA
CCGATGCCGAACTGAAACAGACGCTGTTGATGGCCGGTATTACCCTGTTGGTGGTGCTGCTAAAGCGCAAAGATCTGATG
CTCTACTGTTTCGATCCCAACCATGCCAGAGTGATTGGCCTGCCGGTGAAGCTGTTGCATTACGGATTACTGTGCCTGCT
GGCGCTGACCATTGTCGCTTCGCTGCAGGCGGTGGGGGTGATTCTGGTAATTGCGATGCTGATAGCTCCAGGGATTATTG
CCTTTATGCTGTGCCGCAGCTTCGATCGCATGTTGATGGTCGCCACGGTGGTTTCGGTGTTCTCCTGCGTGCTCGGCACC
TTGATCAGCTTCCACATCGACGGCGCTACCGGCCCCTGCATTGTGATCGTACAGGCGATTCTGTTTGTGGTCGCCCTGCT
CTACAGCAAGTTCAGGCCGTTACAACGTCACGATAACGATTTGCTCAACGCCAAGTCCTGA

Upstream 100 bases:

>100_bases
TGCAGACGCTGGTGTTCCTGGCCGCCTTTTTCTTCGCCCCGAAACACGGCCTGCTGGCATCCAAACGCCGCGTAGCGCGT
GAACAGACCGGAGGCCACTG

Downstream 100 bases:

>100_bases
AACAGGCGGCGGTGCCCAATAGCACCGCCGCCTGATGTTACTGCTGCTGGTAGATATCCGGCCGGACAATGTGCCAGACA
AAATCCTCACGATTCACCGC

Product: ABC-3 protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
METLYQLLSEPFAYPFMQRAILAAIVTGVVCAVLSCYLVLKGWSLMGDAISHAVLPGIVLAFVLGIPVVIGAFFSGIFCA
VATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRVDTDQHLSHILFGNMLGITDAELKQTLLMAGITLLVVLLKRKDLM
LYCFDPNHARVIGLPVKLLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMLCRSFDRMLMVATVVSVFSCVLGT
LISFHIDGATGPCIVIVQAILFVVALLYSKFRPLQRHDNDLLNAKS

Sequences:

>Translated_286_residues
METLYQLLSEPFAYPFMQRAILAAIVTGVVCAVLSCYLVLKGWSLMGDAISHAVLPGIVLAFVLGIPVVIGAFFSGIFCA
VATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRVDTDQHLSHILFGNMLGITDAELKQTLLMAGITLLVVLLKRKDLM
LYCFDPNHARVIGLPVKLLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMLCRSFDRMLMVATVVSVFSCVLGT
LISFHIDGATGPCIVIVQAILFVVALLYSKFRPLQRHDNDLLNAKS
>Mature_286_residues
METLYQLLSEPFAYPFMQRAILAAIVTGVVCAVLSCYLVLKGWSLMGDAISHAVLPGIVLAFVLGIPVVIGAFFSGIFCA
VATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRVDTDQHLSHILFGNMLGITDAELKQTLLMAGITLLVVLLKRKDLM
LYCFDPNHARVIGLPVKLLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMLCRSFDRMLMVATVVSVFSCVLGT
LISFHIDGATGPCIVIVQAILFVVALLYSKFRPLQRHDNDLLNAKS

Specific function: Part of an ATP-driven transport system yfeABCD for chelated iron [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=254, Percent_Identity=25.1968503937008, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 31013; Mature: 31013

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLYQLLSEPFAYPFMQRAILAAIVTGVVCAVLSCYLVLKGWSLMGDAISHAVLPGIVL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVLGIPVVIGAFFSGIFCAVATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRVDTDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
HLSHILFGNMLGITDAELKQTLLMAGITLLVVLLKRKDLMLYCFDPNHARVIGLPVKLLH
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHH
YGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMLCRSFDRMLMVATVVSVFSCVLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISFHIDGATGPCIVIVQAILFVVALLYSKFRPLQRHDNDLLNAKS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
METLYQLLSEPFAYPFMQRAILAAIVTGVVCAVLSCYLVLKGWSLMGDAISHAVLPGIVL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVLGIPVVIGAFFSGIFCAVATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRVDTDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
HLSHILFGNMLGITDAELKQTLLMAGITLLVVLLKRKDLMLYCFDPNHARVIGLPVKLLH
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHH
YGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMLCRSFDRMLMVATVVSVFSCVLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISFHIDGATGPCIVIVQAILFVVALLYSKFRPLQRHDNDLLNAKS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430 [H]