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The map label for this gene is hutI

Identifier: 157370319

GI number: 157370319

Start: 2270406

End: 2271629

Strand: Reverse

Name: hutI

Synonym: Spro_2077

Alternate gene names: 157370319

Gene position: 2271629-2270406 (Counterclockwise)

Preceding gene: 157370320

Following gene: 157370318

Centisome position: 41.69

GC content: 61.03

Gene sequence:

>1224_bases
ATGACTTCTGAGATTCACTGCGACAGCCTGTGGTACGGGGCCGATATCGTCACCATGCGCGACGGCAAGTATCACACCCT
CAGCAACGGCGCGATCGCCACGCGTGACGGCAAAATTGTCTGGCTGGGCGAATATGACGCGCTGCCGGCGACGCTGACCG
CAGATGAAAGGGTAAAATTCGACGGCGGCATCATCACGCCAGGCTTTATCGATTGCCACACCCATCTGGTATTCGGCGGC
AACCGCAGCGCAGAGTTCGAACAGCGCCTGAACGGCGTGAGCTATGCCGAGATCGCCGCTCAGGGCGGCGGCATCATTTC
CACGGTCAAGGCCACCCGCGATGCCGACGAAGAACGGTTACTGGAACAGGCTCTGTTCCGACTACGCCCTCTGCTGGCAG
AAGGTGTGACCTGCGTGGAGATCAAATCCGGTTATGGACTGACGCCGGAAAGTGAAATGAAAATGCTGCGCGTGGCGCGT
CGACTGGGCGAACTGCTGCCGGTAGAGGTGAAAACCACCTGCCTGGCGGCGCACGCCCTGCCGCCGGAATATGCCAACAG
GGCCGACGACTATATCGATTTGGTGTGCAACACCATTATTCCTCAGGCCGCCGCCGCCGGGCTGGCTGATGCGGTTGACG
CTTTTTGTGAACATCTGGCGTTCTCACCGGCCCAGGTGGCACGGGTGTTTGCCGCCGCAGAAGCCGCCGGACTGCCGGTG
AAACTGCACGCCGAACAGCTTTCCGCGCTGGGTGGCAGCGAATTGGCGGCGCAGCACCATGCGCTTTCCGCCGATCACCT
TGAATATGCCACCGAACAGGATGCCCGGGCGATGGGCGACGCCGGTACCGTTGCGGTGCTGTTGCCGGGCGCTTACTACC
TGCTGCGCGAAACCCAATGCCCACCGGTTGATTTATTCCGTAAACACAACGTGGCGATGGCGATTGCCAGCGACGCCAAC
CCTGGTACCTCTCCGGCACTGTCGCTGCGCCTGATGATCAACATGGCCTGTACGCTGTTCCGTCTGACACCGGAAGAAGC
TCTGGCAGGCGTAACGACCCACGCGGCGAAAGCGCTGGGCCTGCAGGCGAGCCACGGCACGCTGGAAACCGGCAAGGTGG
CCGACTTTATACACTGGCCGCTGTCGCGACCGGCTGAACTGGCTTATTGGTTGGGTGGACAACTGCCCTGCACGGTGATT
TTCCGAGGAGAAATACGTCAATGA

Upstream 100 bases:

>100_bases
ATTTTTATCCCGCCTCTTGTGACAACTCAATGAATGCGCTAGGTTGTTTTTAATTGTATATACAACCATGTGGGAGCCAA
GGCTCCGGCGGAGAAAAGCC

Downstream 100 bases:

>100_bases
CCATTCGCGATCCTTTTGATTTCCATGCCGGCAGCCTGCCGCTGCTGATCAGCATTCCCCACGCCGGGACCCGGCTCACT
CCGGCGGTTGAGGCCGGTTT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTSEIHCDSLWYGADIVTMRDGKYHTLSNGAIATRDGKIVWLGEYDALPATLTADERVKFDGGIITPGFIDCHTHLVFGG
NRSAEFEQRLNGVSYAEIAAQGGGIISTVKATRDADEERLLEQALFRLRPLLAEGVTCVEIKSGYGLTPESEMKMLRVAR
RLGELLPVEVKTTCLAAHALPPEYANRADDYIDLVCNTIIPQAAAAGLADAVDAFCEHLAFSPAQVARVFAAAEAAGLPV
KLHAEQLSALGGSELAAQHHALSADHLEYATEQDARAMGDAGTVAVLLPGAYYLLRETQCPPVDLFRKHNVAMAIASDAN
PGTSPALSLRLMINMACTLFRLTPEEALAGVTTHAAKALGLQASHGTLETGKVADFIHWPLSRPAELAYWLGGQLPCTVI
FRGEIRQ

Sequences:

>Translated_407_residues
MTSEIHCDSLWYGADIVTMRDGKYHTLSNGAIATRDGKIVWLGEYDALPATLTADERVKFDGGIITPGFIDCHTHLVFGG
NRSAEFEQRLNGVSYAEIAAQGGGIISTVKATRDADEERLLEQALFRLRPLLAEGVTCVEIKSGYGLTPESEMKMLRVAR
RLGELLPVEVKTTCLAAHALPPEYANRADDYIDLVCNTIIPQAAAAGLADAVDAFCEHLAFSPAQVARVFAAAEAAGLPV
KLHAEQLSALGGSELAAQHHALSADHLEYATEQDARAMGDAGTVAVLLPGAYYLLRETQCPPVDLFRKHNVAMAIASDAN
PGTSPALSLRLMINMACTLFRLTPEEALAGVTTHAAKALGLQASHGTLETGKVADFIHWPLSRPAELAYWLGGQLPCTVI
FRGEIRQ
>Mature_406_residues
TSEIHCDSLWYGADIVTMRDGKYHTLSNGAIATRDGKIVWLGEYDALPATLTADERVKFDGGIITPGFIDCHTHLVFGGN
RSAEFEQRLNGVSYAEIAAQGGGIISTVKATRDADEERLLEQALFRLRPLLAEGVTCVEIKSGYGLTPESEMKMLRVARR
LGELLPVEVKTTCLAAHALPPEYANRADDYIDLVCNTIIPQAAAAGLADAVDAFCEHLAFSPAQVARVFAAAEAAGLPVK
LHAEQLSALGGSELAAQHHALSADHLEYATEQDARAMGDAGTVAVLLPGAYYLLRETQCPPVDLFRKHNVAMAIASDANP
GTSPALSLRLMINMACTLFRLTPEEALAGVTTHAAKALGLQASHGTLETGKVADFIHWPLSRPAELAYWLGGQLPCTVIF
RGEIRQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=384, Percent_Identity=35.15625, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17555004, Length=371, Percent_Identity=33.9622641509434, Blast_Score=204, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_SERP5 (A8GDJ0)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478308.1
- ProteinModelPortal:   A8GDJ0
- SMR:   A8GDJ0
- STRING:   A8GDJ0
- GeneID:   5606597
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2077
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   SPRO399741:SPRO_2077-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43656; Mature: 43525

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: BINDING 82-82 BINDING 95-95 BINDING 145-145 BINDING 178-178 BINDING 246-246

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEIHCDSLWYGADIVTMRDGKYHTLSNGAIATRDGKIVWLGEYDALPATLTADERVKF
CCCCEECCCEEECCEEEEEECCCEEEECCCEEEECCCCEEEEECCCCCCEEECCCCEEEE
DGGIITPGFIDCHTHLVFGGNRSAEFEQRLNGVSYAEIAAQGGGIISTVKATRDADEERL
CCCEECCCEEECEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEHHHCCCHHHHH
LEQALFRLRPLLAEGVTCVEIKSGYGLTPESEMKMLRVARRLGELLPVEVKTTCLAAHAL
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHCC
PPEYANRADDYIDLVCNTIIPQAAAAGLADAVDAFCEHLAFSPAQVARVFAAAEAAGLPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCE
KLHAEQLSALGGSELAAQHHALSADHLEYATEQDARAMGDAGTVAVLLPGAYYLLRETQC
EEEHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCC
PPVDLFRKHNVAMAIASDANPGTSPALSLRLMINMACTLFRLTPEEALAGVTTHAAKALG
CCHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHC
LQASHGTLETGKVADFIHWPLSRPAELAYWLGGQLPCTVIFRGEIRQ
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TSEIHCDSLWYGADIVTMRDGKYHTLSNGAIATRDGKIVWLGEYDALPATLTADERVKF
CCCEECCCEEECCEEEEEECCCEEEECCCEEEECCCCEEEEECCCCCCEEECCCCEEEE
DGGIITPGFIDCHTHLVFGGNRSAEFEQRLNGVSYAEIAAQGGGIISTVKATRDADEERL
CCCEECCCEEECEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEHHHCCCHHHHH
LEQALFRLRPLLAEGVTCVEIKSGYGLTPESEMKMLRVARRLGELLPVEVKTTCLAAHAL
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHCC
PPEYANRADDYIDLVCNTIIPQAAAAGLADAVDAFCEHLAFSPAQVARVFAAAEAAGLPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCE
KLHAEQLSALGGSELAAQHHALSADHLEYATEQDARAMGDAGTVAVLLPGAYYLLRETQC
EEEHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCC
PPVDLFRKHNVAMAIASDANPGTSPALSLRLMINMACTLFRLTPEEALAGVTTHAAKALG
CCHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHC
LQASHGTLETGKVADFIHWPLSRPAELAYWLGGQLPCTVIFRGEIRQ
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA