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The map label for this gene is 157370257

Identifier: 157370257

GI number: 157370257

Start: 2208365

End: 2210143

Strand: Reverse

Name: 157370257

Synonym: Spro_2015

Alternate gene names: NA

Gene position: 2210143-2208365 (Counterclockwise)

Preceding gene: 157370258

Following gene: 157370256

Centisome position: 40.56

GC content: 57.22

Gene sequence:

>1779_bases
ATGAGCGCAATTAAAAAGCCACCGGTAGACGTGGTCATCGTCGGATTTGGCTGGACCGGCGCCATCATGGGAATGGAATT
AACCGAAAGCGGTTTGAGCGTGCTGGCGCTGGAGCGTGGCGAGCAACGCGATACCTACCCGGACTTTGCCTATCCGCGCA
TCGCCGACGAACTGACCTACGGCATTCGCATGAAACTGATGCAGGCAATGGCCAACGAAACGGTCACCGTGCGCCACACC
CCGGCGGATTTCGCCGTGCCCTACCGTCAACTGGGCTCATTTTTGCCGGGTAACGGCGTTGGCGGTGCCGGCGTACACTG
GAACGGCATGCATTGGCGCGCTTTGCCCTCCGACTTAAAGCTACACACCACCCTCAACGAAAAATACGGAGCCAAATGGA
TCCCGGAAGGCATGACGCTGCAGGACTATCCGTTGAGTTACCAGGAGCTGGAACCTTACTTCGACAAGTTCGAAAAGGTC
TGCGGCACCGCGGGTAAAGCCGGCAATCTTCGCGGGCAAATCATCAAGGGCGGCAACCCGTTCGAAGGGCCACGCAACAG
CGAATACCCCACTCCGGCGCTGAAACGGCTCTATTCCGGTTCGCTGTTTGCCCCCGCGGCGGAATCACTGGGTTATCACC
CCTTCAGCGTGCCCGCCGCCAACTGCTCCGAGCCTTACACCAATCCCTATGGCGTACAGCTCGGCCCCTGCAACTACTGC
GGTTACTGCGAACGTTTTGGCTGCTTTATGTATTCCAAGGCCTCGCCGCAGAGCACCATCCTGCCGGTGCTGACCCAACG
TAAAAACTTTGAGCTACGTACCCAGTCGCAGGTAATCAAAGTGAATCTGGACAGCACGGGCAAGAAAGCCACCGGCGTCA
CCTACATCAACGCTCAGGGGCAAGAGGTGGAGCAACCGGCGGATCTGGTGATACTCAGCGCCTTCCAGCTACATAACGTC
CGCCTGCTGCTGCTGTCGGGCATTGGCAAACCTTATAACCCGGTGACCGGCGAAGGCGTGGTCGGCAAGAATTACGCCTA
TCAGATGAACAGCAATATTTCGCTGTTCTACGACAAGGATATCCACTTCAATCCCTTTATCGGTGCCGGGGCCGCCGGTA
CGGTGATCGACGATCTGAACGGTGAGAATTTCGATCATGCCGATTTGGGCTTTATCGGCGGCGCCTATATCTCCGCCACC
CGCACCGGCGGCCGACCGCTGCAGCAGATGATGCTGCCGGCGGGCACCCCAACCTGGGGCAGCGGCTGGAAACAGGGCAT
CAAAGATAACTATCTGCACAGCATGAGCATCAACTCCGAAGGCTCGGTGATGCCGTACCGCGATTGCTATCTGGATTTGG
ATCCTACTTACAAGGACGGTTACGGCCTGCCGCTGTTGCGCATGACTTTTGACTGGAAGGACAACGAGATCAAAATGACC
CAGCACATCACCGGCAAAATGGTGGATATTGCCAAAGTGATGAAACCCAAGCAGATGTCGGTCTCGGTGATGAAAGCCGG
CGATCATTACGACGTGCGGCCTTACCAGTCGACCCATACCACTGGCGGGGCCATTACCGGCGATAATCCGGCCACCAGCG
TGGTGAATAAATACCTGCAATGCTGGGACGTGCCAAACGTGTTTGTCACCGGTGCCTGTGCCTTCCCACAGAATCTGGCC
TATAACCCCACCGGCATCGTTGGCGCATTGGCCTACTACTCGGCAGAGGCGATCCGCACTCAGTATTTGAAAAATCCCGG
TCCCCTGGTTCAGGCCTGA

Upstream 100 bases:

>100_bases
TTTCCCCGGCGCGCGTGCGGATTACACCGACTGGGTCAATCGTCCCAATCAGCCTTATCCCCTCGGCCCGGTCAGTATCT
CAAGCAAAAGGAATGCATAA

Downstream 100 bases:

>100_bases
TAGCATAAGGAGCTTCACATGAAAGGACTTACCCCCTCGCTGCTGGCGCTGTTGATGCTGGGTGCCACCACGGTGCAGGC
GAACGACGATCCGCAACTGG

Product: gluconate 2-dehydrogenase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSAIKKPPVDVVIVGFGWTGAIMGMELTESGLSVLALERGEQRDTYPDFAYPRIADELTYGIRMKLMQAMANETVTVRHT
PADFAVPYRQLGSFLPGNGVGGAGVHWNGMHWRALPSDLKLHTTLNEKYGAKWIPEGMTLQDYPLSYQELEPYFDKFEKV
CGTAGKAGNLRGQIIKGGNPFEGPRNSEYPTPALKRLYSGSLFAPAAESLGYHPFSVPAANCSEPYTNPYGVQLGPCNYC
GYCERFGCFMYSKASPQSTILPVLTQRKNFELRTQSQVIKVNLDSTGKKATGVTYINAQGQEVEQPADLVILSAFQLHNV
RLLLLSGIGKPYNPVTGEGVVGKNYAYQMNSNISLFYDKDIHFNPFIGAGAAGTVIDDLNGENFDHADLGFIGGAYISAT
RTGGRPLQQMMLPAGTPTWGSGWKQGIKDNYLHSMSINSEGSVMPYRDCYLDLDPTYKDGYGLPLLRMTFDWKDNEIKMT
QHITGKMVDIAKVMKPKQMSVSVMKAGDHYDVRPYQSTHTTGGAITGDNPATSVVNKYLQCWDVPNVFVTGACAFPQNLA
YNPTGIVGALAYYSAEAIRTQYLKNPGPLVQA

Sequences:

>Translated_592_residues
MSAIKKPPVDVVIVGFGWTGAIMGMELTESGLSVLALERGEQRDTYPDFAYPRIADELTYGIRMKLMQAMANETVTVRHT
PADFAVPYRQLGSFLPGNGVGGAGVHWNGMHWRALPSDLKLHTTLNEKYGAKWIPEGMTLQDYPLSYQELEPYFDKFEKV
CGTAGKAGNLRGQIIKGGNPFEGPRNSEYPTPALKRLYSGSLFAPAAESLGYHPFSVPAANCSEPYTNPYGVQLGPCNYC
GYCERFGCFMYSKASPQSTILPVLTQRKNFELRTQSQVIKVNLDSTGKKATGVTYINAQGQEVEQPADLVILSAFQLHNV
RLLLLSGIGKPYNPVTGEGVVGKNYAYQMNSNISLFYDKDIHFNPFIGAGAAGTVIDDLNGENFDHADLGFIGGAYISAT
RTGGRPLQQMMLPAGTPTWGSGWKQGIKDNYLHSMSINSEGSVMPYRDCYLDLDPTYKDGYGLPLLRMTFDWKDNEIKMT
QHITGKMVDIAKVMKPKQMSVSVMKAGDHYDVRPYQSTHTTGGAITGDNPATSVVNKYLQCWDVPNVFVTGACAFPQNLA
YNPTGIVGALAYYSAEAIRTQYLKNPGPLVQA
>Mature_591_residues
SAIKKPPVDVVIVGFGWTGAIMGMELTESGLSVLALERGEQRDTYPDFAYPRIADELTYGIRMKLMQAMANETVTVRHTP
ADFAVPYRQLGSFLPGNGVGGAGVHWNGMHWRALPSDLKLHTTLNEKYGAKWIPEGMTLQDYPLSYQELEPYFDKFEKVC
GTAGKAGNLRGQIIKGGNPFEGPRNSEYPTPALKRLYSGSLFAPAAESLGYHPFSVPAANCSEPYTNPYGVQLGPCNYCG
YCERFGCFMYSKASPQSTILPVLTQRKNFELRTQSQVIKVNLDSTGKKATGVTYINAQGQEVEQPADLVILSAFQLHNVR
LLLLSGIGKPYNPVTGEGVVGKNYAYQMNSNISLFYDKDIHFNPFIGAGAAGTVIDDLNGENFDHADLGFIGGAYISATR
TGGRPLQQMMLPAGTPTWGSGWKQGIKDNYLHSMSINSEGSVMPYRDCYLDLDPTYKDGYGLPLLRMTFDWKDNEIKMTQ
HITGKMVDIAKVMKPKQMSVSVMKAGDHYDVRPYQSTHTTGGAITGDNPATSVVNKYLQCWDVPNVFVTGACAFPQNLAY
NPTGIVGALAYYSAEAIRTQYLKNPGPLVQA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 64918; Mature: 64786

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIKKPPVDVVIVGFGWTGAIMGMELTESGLSVLALERGEQRDTYPDFAYPRIADELTY
CCCCCCCCCCEEEECCCCHHHHCCEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
GIRMKLMQAMANETVTVRHTPADFAVPYRQLGSFLPGNGVGGAGVHWNGMHWRALPSDLK
HHHHHHHHHHHCCEEEEEECCCHHCCCHHHHCCCCCCCCCCCCCEEECCEEEEECCCCCE
LHTTLNEKYGAKWIPEGMTLQDYPLSYQELEPYFDKFEKVCGTAGKAGNLRGQIIKGGNP
EEEEECCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
FEGPRNSEYPTPALKRLYSGSLFAPAAESLGYHPFSVPAANCSEPYTNPYGVQLGPCNYC
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GYCERFGCFMYSKASPQSTILPVLTQRKNFELRTQSQVIKVNLDSTGKKATGVTYINAQG
CHHHHHCEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCEEEEECCC
QEVEQPADLVILSAFQLHNVRLLLLSGIGKPYNPVTGEGVVGKNYAYQMNSNISLFYDKD
CCCCCCCCEEEEEHHHHCCEEEEEEECCCCCCCCCCCCCEECCCEEEEECCCEEEEEECC
IHFNPFIGAGAAGTVIDDLNGENFDHADLGFIGGAYISATRTGGRPLQQMMLPAGTPTWG
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCC
SGWKQGIKDNYLHSMSINSEGSVMPYRDCYLDLDPTYKDGYGLPLLRMTFDWKDNEIKMT
CHHHHCCCCCCEEEEEECCCCCCCCHHHEEEECCCCCCCCCCCEEEEEEECCCCCEEEEE
QHITGKMVDIAKVMKPKQMSVSVMKAGDHYDVRPYQSTHTTGGAITGDNPATSVVNKYLQ
ECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHH
CWDVPNVFVTGACAFPQNLAYNPTGIVGALAYYSAEAIRTQYLKNPGPLVQA
HCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAIKKPPVDVVIVGFGWTGAIMGMELTESGLSVLALERGEQRDTYPDFAYPRIADELTY
CCCCCCCCCEEEECCCCHHHHCCEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
GIRMKLMQAMANETVTVRHTPADFAVPYRQLGSFLPGNGVGGAGVHWNGMHWRALPSDLK
HHHHHHHHHHHCCEEEEEECCCHHCCCHHHHCCCCCCCCCCCCCEEECCEEEEECCCCCE
LHTTLNEKYGAKWIPEGMTLQDYPLSYQELEPYFDKFEKVCGTAGKAGNLRGQIIKGGNP
EEEEECCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
FEGPRNSEYPTPALKRLYSGSLFAPAAESLGYHPFSVPAANCSEPYTNPYGVQLGPCNYC
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GYCERFGCFMYSKASPQSTILPVLTQRKNFELRTQSQVIKVNLDSTGKKATGVTYINAQG
CHHHHHCEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCEEEEECCC
QEVEQPADLVILSAFQLHNVRLLLLSGIGKPYNPVTGEGVVGKNYAYQMNSNISLFYDKD
CCCCCCCCEEEEEHHHHCCEEEEEEECCCCCCCCCCCCCEECCCEEEEECCCEEEEEECC
IHFNPFIGAGAAGTVIDDLNGENFDHADLGFIGGAYISATRTGGRPLQQMMLPAGTPTWG
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCC
SGWKQGIKDNYLHSMSINSEGSVMPYRDCYLDLDPTYKDGYGLPLLRMTFDWKDNEIKMT
CHHHHCCCCCCEEEEEECCCCCCCCHHHEEEECCCCCCCCCCCEEEEEEECCCCCEEEEE
QHITGKMVDIAKVMKPKQMSVSVMKAGDHYDVRPYQSTHTTGGAITGDNPATSVVNKYLQ
ECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHH
CWDVPNVFVTGACAFPQNLAYNPTGIVGALAYYSAEAIRTQYLKNPGPLVQA
HCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]