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The map label for this gene is yhcK [H]

Identifier: 157370239

GI number: 157370239

Start: 2185202

End: 2186302

Strand: Direct

Name: yhcK [H]

Synonym: Spro_1997

Alternate gene names: 157370239

Gene position: 2185202-2186302 (Clockwise)

Preceding gene: 157370236

Following gene: 157370242

Centisome position: 40.1

GC content: 53.41

Gene sequence:

>1101_bases
ATGACTTACGTTGCGTCAATCCCCTCCCTGTTTAGTGACGCCTGCATTACCTATGCAACACTGTCAGTCAGCTATTTTGC
CCTCAGCAAAAACGCCCCCTTTTCCTATCAGTCAGAAGCCTGGAAACGCGGGCTTTTCGGCCTGTTAGCCGGGCTGACGA
CGCTGTTTCTGAATCAGAACCGGTTGGAGCTGGCTGGCAACGTGCATTACAGCTTCGCCATGATCCCGATGATATTGGTG
ACCTTCTATGGTGGTGCACTCAGTGGGTTGGTGTGCTACCTGACGTCGTTGGCTTTGAGCGGCGGCTTCACCGTCGATAA
CTTGTTTATCGGTTCGATCATCATTCCGTTGCTGTTGTCGCGGGTCTGGCTGAGAAAGTCGAATAGGGTGTTCTACCTGA
CTATCGGTGTGATTGCGTTATACCGTATCGCGGTGGTTTGGTTTTGGGTCGATATGTGGACGCTGTGGCTGGATGTGTTG
CTGTATCAAGTCATCGCTGCCCTGTGTCTGGCGATTTGCTACCATGCGCTGAACTTCAAAGAGCGGCATATCCATGCCTA
TTTCTCGATGCGTGATAAAGCCACCACCGACAGCCTGACCCACATAAGTAACCGCGCCAGCGTCGATTACCGGTTGATGC
TGCAACAGGCGGAACGGCGTCCTTGCGGGTTGATGATCCTCGATCTGGATAATTTCAAGCGTATCAACGACACCTACGGT
CATTTGGCCGGAGATCTGTTGCTGACCCAGATGGGACAGTTGTTGCAAAACAGCGTGCGTAGCGAAGATTTTGTCGGTCG
CTATGGCGGTGAGGAGTTTATGGTGATCACCGCCAGCTATGATCCGAAGATTATCGGCGGGGTAGCGGAACGCATTCGTC
GCAGCGTGGAGACAACGATATTTTTGCTCGATGAAGGCAACGAGACACAAATCACCGTCTCTATCGGTGCCTCACTGTAT
CTGCCCGGTATGGCGGTAGATAAAGCCATAGAGGTGACGGACGAAGCCCTGTATGAGGCCAAACGTGGCGGGAAAAACCA
GGTGGTCTGCAGCCGGCTGATGCCGTTTTCGCCCCTGGGGGCCGGCTTTCGGCAGCAATAA

Upstream 100 bases:

>100_bases
CGAGTAATATGTTCCATGCCGGAATGGATGAGACAGGGATTGGTGCTCAAAATTTATTGCTTAATCACCCTGTAATTTCC
GCGGAGCATAGCGAATATTT

Downstream 100 bases:

>100_bases
CCCCTCCTGACGGATCAGAAGGGGTTATTGGCTCAGGCCGCCAGCGTATGCTCGCGGAATGCGGTCAACAGCTCTTCGGT
AAATTTCAGGCGTTTCTGGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTYVASIPSLFSDACITYATLSVSYFALSKNAPFSYQSEAWKRGLFGLLAGLTTLFLNQNRLELAGNVHYSFAMIPMILV
TFYGGALSGLVCYLTSLALSGGFTVDNLFIGSIIIPLLLSRVWLRKSNRVFYLTIGVIALYRIAVVWFWVDMWTLWLDVL
LYQVIAALCLAICYHALNFKERHIHAYFSMRDKATTDSLTHISNRASVDYRLMLQQAERRPCGLMILDLDNFKRINDTYG
HLAGDLLLTQMGQLLQNSVRSEDFVGRYGGEEFMVITASYDPKIIGGVAERIRRSVETTIFLLDEGNETQITVSIGASLY
LPGMAVDKAIEVTDEALYEAKRGGKNQVVCSRLMPFSPLGAGFRQQ

Sequences:

>Translated_366_residues
MTYVASIPSLFSDACITYATLSVSYFALSKNAPFSYQSEAWKRGLFGLLAGLTTLFLNQNRLELAGNVHYSFAMIPMILV
TFYGGALSGLVCYLTSLALSGGFTVDNLFIGSIIIPLLLSRVWLRKSNRVFYLTIGVIALYRIAVVWFWVDMWTLWLDVL
LYQVIAALCLAICYHALNFKERHIHAYFSMRDKATTDSLTHISNRASVDYRLMLQQAERRPCGLMILDLDNFKRINDTYG
HLAGDLLLTQMGQLLQNSVRSEDFVGRYGGEEFMVITASYDPKIIGGVAERIRRSVETTIFLLDEGNETQITVSIGASLY
LPGMAVDKAIEVTDEALYEAKRGGKNQVVCSRLMPFSPLGAGFRQQ
>Mature_365_residues
TYVASIPSLFSDACITYATLSVSYFALSKNAPFSYQSEAWKRGLFGLLAGLTTLFLNQNRLELAGNVHYSFAMIPMILVT
FYGGALSGLVCYLTSLALSGGFTVDNLFIGSIIIPLLLSRVWLRKSNRVFYLTIGVIALYRIAVVWFWVDMWTLWLDVLL
YQVIAALCLAICYHALNFKERHIHAYFSMRDKATTDSLTHISNRASVDYRLMLQQAERRPCGLMILDLDNFKRINDTYGH
LAGDLLLTQMGQLLQNSVRSEDFVGRYGGEEFMVITASYDPKIIGGVAERIRRSVETTIFLLDEGNETQITVSIGASLYL
PGMAVDKAIEVTDEALYEAKRGGKNQVVCSRLMPFSPLGAGFRQQ

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=37.037037037037, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=35.2601156069364, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082007, Length=169, Percent_Identity=34.3195266272189, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=35.2201257861635, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=31.6770186335404, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788381, Length=162, Percent_Identity=34.5679012345679, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081881, Length=129, Percent_Identity=36.4341085271318, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787541, Length=184, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787802, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081974, Length=216, Percent_Identity=25.9259259259259, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081977, Length=253, Percent_Identity=26.4822134387352, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=32.3353293413174, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=32.9341317365269, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 40972; Mature: 40841

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYVASIPSLFSDACITYATLSVSYFALSKNAPFSYQSEAWKRGLFGLLAGLTTLFLNQN
CCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RLELAGNVHYSFAMIPMILVTFYGGALSGLVCYLTSLALSGGFTVDNLFIGSIIIPLLLS
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RVWLRKSNRVFYLTIGVIALYRIAVVWFWVDMWTLWLDVLLYQVIAALCLAICYHALNFK
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERHIHAYFSMRDKATTDSLTHISNRASVDYRLMLQQAERRPCGLMILDLDNFKRINDTYG
HHHEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
HLAGDLLLTQMGQLLQNSVRSEDFVGRYGGEEFMVITASYDPKIIGGVAERIRRSVETTI
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCEEE
FLLDEGNETQITVSIGASLYLPGMAVDKAIEVTDEALYEAKRGGKNQVVCSRLMPFSPLG
EEEECCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
AGFRQQ
CCCCCC
>Mature Secondary Structure 
TYVASIPSLFSDACITYATLSVSYFALSKNAPFSYQSEAWKRGLFGLLAGLTTLFLNQN
CCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RLELAGNVHYSFAMIPMILVTFYGGALSGLVCYLTSLALSGGFTVDNLFIGSIIIPLLLS
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RVWLRKSNRVFYLTIGVIALYRIAVVWFWVDMWTLWLDVLLYQVIAALCLAICYHALNFK
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERHIHAYFSMRDKATTDSLTHISNRASVDYRLMLQQAERRPCGLMILDLDNFKRINDTYG
HHHEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
HLAGDLLLTQMGQLLQNSVRSEDFVGRYGGEEFMVITASYDPKIIGGVAERIRRSVETTI
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCEEE
FLLDEGNETQITVSIGASLYLPGMAVDKAIEVTDEALYEAKRGGKNQVVCSRLMPFSPLG
EEEECCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
AGFRQQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]