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The map label for this gene is ltrA [H]

Identifier: 157370197

GI number: 157370197

Start: 2136104

End: 2137036

Strand: Reverse

Name: ltrA [H]

Synonym: Spro_1955

Alternate gene names: 157370197

Gene position: 2137036-2136104 (Counterclockwise)

Preceding gene: 157370200

Following gene: 157370189

Centisome position: 39.22

GC content: 60.56

Gene sequence:

>933_bases
ATGCAGAAAGGCATCTTGAAGGACCTGAACGACCTCTATTATTTTGCCCAGGTCGCCCAATACGGCGGGTTCTCCGCCGC
CAGCCGGGCGCTGGATATTCCGAAATCCAAACTGAGCGCACGCGTGCTGGCGCTGGAGAATCGTCTTGGCGTGTTGCTGT
TCCAGCGCACCACCCGACGGGTCAAACTGACGGAGACCGGTTCGTTGCTGCTGCGCCATGCGCAGGTAGCGATCAACGAG
GCCGAGATCGCCCAGGAACTGATTGACCAAAGCCGGGCAGAACCTTCCGGGTTGGTGCGCGTAAGCTGCCCGAAACTGGC
CGCCGATGTCCTGCTTTCCCCCTGTCTGCCGGCTTTTATGGCCGCCAACCCCGGTATTCAGGTGCAGTTGCTGGCGAACG
ATAACCGCTTTGACCCGGTGACCGACAAGATTGATGTGGCGCTGCGTCTGCGCCAGCGCAAAGACATGAGTGAGGGTATG
ATTGCCCGTGAGCTGGGCCAAAGCGTGCGCATCCTGGTCGCCTCGCCGCAGTATCTGGCGCAGCACCCGTCGCTGACCGA
TCCGCAGCAATTGAGCGAACATGCGCTGTTAACCCTGGTCGACGTCAGCGAACAGCAAACCTGGGATCTGGAAGGCCCCG
ATGGGGAAAAACGCGCGGTGCGTGTGCGCCCGCGGCTGATGTGCAGCGAATGGGGGATCCTCCGCGGTGCGCTTTATCAA
CACCTGGGTATTGCGCTGCTGCCGGATATCACCTGCCATCAGGCATTGATGCAGGGTGAGCTGGTGCGTGTGTTGCCACA
ATGGGCCTGTGCGCCACTGATCATGCATGCCGTGTTCCCGACCCGGCGCGGTATGCTGCCTTCGGTACGCGCACTGGTGG
ATTTTTTGGCAATACAGGTACCGCCACTGCTGCTGAAAGGCGCGGTTAAATAG

Upstream 100 bases:

>100_bases
CCTGGTGCCGTTGTTTCGATGTGGGCAGTATAAGATGGGTTATTGGGTGTAAAAAGATGTCATACTCTGACTCACTGTTC
TCAAATTAAGGACAATATGA

Downstream 100 bases:

>100_bases
CACATCAACACCAGAATTTCTCTCCGCGTCAGGCCTCAACGATGATGTTTAAAGTCCGGGGAATTCATCCCCCGCCCCGG
AGAGTGGCAAAGTTTGCCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQKGILKDLNDLYYFAQVAQYGGFSAASRALDIPKSKLSARVLALENRLGVLLFQRTTRRVKLTETGSLLLRHAQVAINE
AEIAQELIDQSRAEPSGLVRVSCPKLAADVLLSPCLPAFMAANPGIQVQLLANDNRFDPVTDKIDVALRLRQRKDMSEGM
IARELGQSVRILVASPQYLAQHPSLTDPQQLSEHALLTLVDVSEQQTWDLEGPDGEKRAVRVRPRLMCSEWGILRGALYQ
HLGIALLPDITCHQALMQGELVRVLPQWACAPLIMHAVFPTRRGMLPSVRALVDFLAIQVPPLLLKGAVK

Sequences:

>Translated_310_residues
MQKGILKDLNDLYYFAQVAQYGGFSAASRALDIPKSKLSARVLALENRLGVLLFQRTTRRVKLTETGSLLLRHAQVAINE
AEIAQELIDQSRAEPSGLVRVSCPKLAADVLLSPCLPAFMAANPGIQVQLLANDNRFDPVTDKIDVALRLRQRKDMSEGM
IARELGQSVRILVASPQYLAQHPSLTDPQQLSEHALLTLVDVSEQQTWDLEGPDGEKRAVRVRPRLMCSEWGILRGALYQ
HLGIALLPDITCHQALMQGELVRVLPQWACAPLIMHAVFPTRRGMLPSVRALVDFLAIQVPPLLLKGAVK
>Mature_310_residues
MQKGILKDLNDLYYFAQVAQYGGFSAASRALDIPKSKLSARVLALENRLGVLLFQRTTRRVKLTETGSLLLRHAQVAINE
AEIAQELIDQSRAEPSGLVRVSCPKLAADVLLSPCLPAFMAANPGIQVQLLANDNRFDPVTDKIDVALRLRQRKDMSEGM
IARELGQSVRILVASPQYLAQHPSLTDPQQLSEHALLTLVDVSEQQTWDLEGPDGEKRAVRVRPRLMCSEWGILRGALYQ
HLGIALLPDITCHQALMQGELVRVLPQWACAPLIMHAVFPTRRGMLPSVRALVDFLAIQVPPLLLKGAVK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=30.8771929824561, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=29.4915254237288, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=30.2405498281787, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=29.7945205479452, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=26.6891891891892, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787589, Length=306, Percent_Identity=28.4313725490196, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=27.1477663230241, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789173, Length=201, Percent_Identity=30.3482587064677, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786448, Length=140, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=127, Percent_Identity=34.6456692913386, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790011, Length=298, Percent_Identity=24.496644295302, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790399, Length=123, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34283; Mature: 34283

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGILKDLNDLYYFAQVAQYGGFSAASRALDIPKSKLSARVLALENRLGVLLFQRTTRR
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCE
VKLTETGSLLLRHAQVAINEAEIAQELIDQSRAEPSGLVRVSCPKLAADVLLSPCLPAFM
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AANPGIQVQLLANDNRFDPVTDKIDVALRLRQRKDMSEGMIARELGQSVRILVASPQYLA
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHCCHHHHHCCCCEEEEEECCHHHH
QHPSLTDPQQLSEHALLTLVDVSEQQTWDLEGPDGEKRAVRVRPRLMCSEWGILRGALYQ
CCCCCCCHHHHHHHHEEEEEECCCCCEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHH
HLGIALLPDITCHQALMQGELVRVLPQWACAPLIMHAVFPTRRGMLPSVRALVDFLAIQV
HCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
PPLLLKGAVK
CHHHHCCCCC
>Mature Secondary Structure
MQKGILKDLNDLYYFAQVAQYGGFSAASRALDIPKSKLSARVLALENRLGVLLFQRTTRR
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCE
VKLTETGSLLLRHAQVAINEAEIAQELIDQSRAEPSGLVRVSCPKLAADVLLSPCLPAFM
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AANPGIQVQLLANDNRFDPVTDKIDVALRLRQRKDMSEGMIARELGQSVRILVASPQYLA
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHCCHHHHHCCCCEEEEEECCHHHH
QHPSLTDPQQLSEHALLTLVDVSEQQTWDLEGPDGEKRAVRVRPRLMCSEWGILRGALYQ
CCCCCCCHHHHHHHHEEEEEECCCCCEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHH
HLGIALLPDITCHQALMQGELVRVLPQWACAPLIMHAVFPTRRGMLPSVRALVDFLAIQV
HCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
PPLLLKGAVK
CHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]