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The map label for this gene is ptrB [H]

Identifier: 157370179

GI number: 157370179

Start: 2121440

End: 2123473

Strand: Direct

Name: ptrB [H]

Synonym: Spro_1937

Alternate gene names: 157370179

Gene position: 2121440-2123473 (Clockwise)

Preceding gene: 157370178

Following gene: 157370181

Centisome position: 38.93

GC content: 56.1

Gene sequence:

>2034_bases
ATGATGACACCCCCTAAGGCAGAAAAACGACCTTATCCCATTACTACCCACGGCGACACGCGGGTAGATGACTATTATTG
GCTGCGCGACGACGAGCGCGCAGACCCGCAGGTGCTGGACTATCTGCAGGCGGAAAACGCCTTTACCGACGCGGTATTGA
AACCGCAACAGGCGCTGCGCGAAACTCTGTATGAAGAGATGGTGGCGCGTATTCCTCAGCAGGAACATTCGGTGCCTTAC
GTCCGACACGGCTACCGCTATCAGACCCGCTTTGAACCGGGCAATGAATACGCGATTTACGTCCGCCAACCGCAGGCCGA
GAGCGAGCATTGGGATATCCTGATCGACGGCAATCAACGTGCCGAGCAGCGTGAGTTTTATACCCTCGGCGGGCTGGAAG
TCAGTCCCGATAACCAAAAACTGGCGGTTGCGGAAGATTTTCTCTCTCGTCGCCAGTACGACATTCGTTTCAAAAACCTC
AGCGACGATAGCTGGACCGACGAAGTGCTGGAAAACACCTCCGGCAGCTTTGAATGGGCCAACGACTCGGCCACCGTGTA
TTACGTACGCAAACACGCCAAAACGTTGCTGCCTTATCAGGTCTATCGCCACGTGGTGGGCACCGATCCGCAGCTCGATG
AGCTGATCTACGAAGAAAAGGATGACACCTTCTACGTCGGGTTGGAAAAGACCACCTCCGATCGTTTTATTCTGATCCAT
CTGAGCAGCACCACCACCTCGGAAATCCTGCTGCTGGACGCCGATCGCGCCGACAGCAAGCCGCAGATGTTTGTGCCGCG
TCGTAAGGATCATGAATACGGTATCGATCACTATCACCAGCATTTCTATATCCGTTCCAACAAGGACGGCAAGAACTTCG
GCCTGTATCAAAGTGATCAGGCGGATGAAGCGCAGTGGCAGACGCTGATCGCTCCGCGCATCGAAGTGATGCTGGAGGGC
TTTAGCCTGTTCCGTGACTGGCTGGTGGTGGAGGAGCGCAGCGAAGGTCTGACCCAACTGCGACAGATCCACTGGCAGAG
CGGCGAAGTGAAGCGCATTGCCTTCGACGACCCCACCTACACCACCTGGCTGGCGTACAACCCGGAACCGGAAACCGAGC
TACTGCGCTATGGCTATTCTTCGATGACCACGCCGACCACGCTGTATGAGCTTAATCTCGACAGCGGTGAGCGCGTGATG
CTCAAACAGCAGGAAGTGAAAAACTTCACTCCGGAAAATTACCGTAGCGAGCGGGTATGGGTGAAGGCGCGTGATGGCGT
TGAAGTCCCGGTTTCGCTGGTCTACCGCCACGATAAATTTACGCGCGGCACCAACCCGCTGATGGTGTATGGCTACGGCT
CTTACGGCAGCAGCATGGATCCGGCCTTCAGCGCCAGCCGCTTAAGCCTGTTGGATCGCGGTTTTGTGTTTGTGCTGGCG
CACATTCGCGGCGGCGGTGAGCTGGGGCAACTGTGGTATGAAGACGGCAAACTGTTCAAAAAGCAAAACACCTTCAACGA
TTTCATCGACGTGACCGAGGCGTTGATCGCCCAGGGTTACGGTGACGCCAAACGGGTATTTGCCATGGGTGGCAGTGCCG
GTGGCTTGCTGATGGGCGCGGTGATTAACCAGGCACCCAGGTTGTTCAACGGCATTGTGGCGCAGGTGCCTTTTGTTGAT
GTGGTCACCACCATGCTCGACGAGTCAATTCCGCTGACGACCGGCGAGTACGACGAATGGGGCAACCCGAACGAGCAGGC
CTACTACGACTACATTTTGCAATACAGCCCTTACGATCAGGTCAAGGCGCAGGATTATCCGCATATGCTGGTCACCACCG
GTTTGCATGACTCTCAGGTACAGTATTGGGAGCCGGCCAAGTGGGTGGCCAAGCTGCGTGAGTTGAAGACCGACGATCGC
CAGCTGTTGCTGTATACCGATATGGATTCCGGCCACGGCGGCAAGTCCGGGCGTTTCAAAGCTTATGAAGATATCGCGCT
GGAGTACGCCTTTATTCTGGCGCTGGCGGAGTAA

Upstream 100 bases:

>100_bases
ACGTCAACGAGAAAAAGCGCGAGCTGGCATAGCGCCGCTTGGCAAGCCGGGGGGAATCGTGTCACTCTTGCCTTAATCAA
GGTAAGCGGATGATTTAGCA

Downstream 100 bases:

>100_bases
CCTTCAGGCGGGCGGCTGGCGCTGCCCGCTTTTCTCAACCAATCAGATAGTATTTCAGCGTGTGCTTCATGTCCGGACTG
AGGTCTTCGATAGATTTCAG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MMTPPKAEKRPYPITTHGDTRVDDYYWLRDDERADPQVLDYLQAENAFTDAVLKPQQALRETLYEEMVARIPQQEHSVPY
VRHGYRYQTRFEPGNEYAIYVRQPQAESEHWDILIDGNQRAEQREFYTLGGLEVSPDNQKLAVAEDFLSRRQYDIRFKNL
SDDSWTDEVLENTSGSFEWANDSATVYYVRKHAKTLLPYQVYRHVVGTDPQLDELIYEEKDDTFYVGLEKTTSDRFILIH
LSSTTTSEILLLDADRADSKPQMFVPRRKDHEYGIDHYHQHFYIRSNKDGKNFGLYQSDQADEAQWQTLIAPRIEVMLEG
FSLFRDWLVVEERSEGLTQLRQIHWQSGEVKRIAFDDPTYTTWLAYNPEPETELLRYGYSSMTTPTTLYELNLDSGERVM
LKQQEVKNFTPENYRSERVWVKARDGVEVPVSLVYRHDKFTRGTNPLMVYGYGSYGSSMDPAFSASRLSLLDRGFVFVLA
HIRGGGELGQLWYEDGKLFKKQNTFNDFIDVTEALIAQGYGDAKRVFAMGGSAGGLLMGAVINQAPRLFNGIVAQVPFVD
VVTTMLDESIPLTTGEYDEWGNPNEQAYYDYILQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLRELKTDDR
QLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILALAE

Sequences:

>Translated_677_residues
MMTPPKAEKRPYPITTHGDTRVDDYYWLRDDERADPQVLDYLQAENAFTDAVLKPQQALRETLYEEMVARIPQQEHSVPY
VRHGYRYQTRFEPGNEYAIYVRQPQAESEHWDILIDGNQRAEQREFYTLGGLEVSPDNQKLAVAEDFLSRRQYDIRFKNL
SDDSWTDEVLENTSGSFEWANDSATVYYVRKHAKTLLPYQVYRHVVGTDPQLDELIYEEKDDTFYVGLEKTTSDRFILIH
LSSTTTSEILLLDADRADSKPQMFVPRRKDHEYGIDHYHQHFYIRSNKDGKNFGLYQSDQADEAQWQTLIAPRIEVMLEG
FSLFRDWLVVEERSEGLTQLRQIHWQSGEVKRIAFDDPTYTTWLAYNPEPETELLRYGYSSMTTPTTLYELNLDSGERVM
LKQQEVKNFTPENYRSERVWVKARDGVEVPVSLVYRHDKFTRGTNPLMVYGYGSYGSSMDPAFSASRLSLLDRGFVFVLA
HIRGGGELGQLWYEDGKLFKKQNTFNDFIDVTEALIAQGYGDAKRVFAMGGSAGGLLMGAVINQAPRLFNGIVAQVPFVD
VVTTMLDESIPLTTGEYDEWGNPNEQAYYDYILQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLRELKTDDR
QLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILALAE
>Mature_677_residues
MMTPPKAEKRPYPITTHGDTRVDDYYWLRDDERADPQVLDYLQAENAFTDAVLKPQQALRETLYEEMVARIPQQEHSVPY
VRHGYRYQTRFEPGNEYAIYVRQPQAESEHWDILIDGNQRAEQREFYTLGGLEVSPDNQKLAVAEDFLSRRQYDIRFKNL
SDDSWTDEVLENTSGSFEWANDSATVYYVRKHAKTLLPYQVYRHVVGTDPQLDELIYEEKDDTFYVGLEKTTSDRFILIH
LSSTTTSEILLLDADRADSKPQMFVPRRKDHEYGIDHYHQHFYIRSNKDGKNFGLYQSDQADEAQWQTLIAPRIEVMLEG
FSLFRDWLVVEERSEGLTQLRQIHWQSGEVKRIAFDDPTYTTWLAYNPEPETELLRYGYSSMTTPTTLYELNLDSGERVM
LKQQEVKNFTPENYRSERVWVKARDGVEVPVSLVYRHDKFTRGTNPLMVYGYGSYGSSMDPAFSASRLSLLDRGFVFVLA
HIRGGGELGQLWYEDGKLFKKQNTFNDFIDVTEALIAQGYGDAKRVFAMGGSAGGLLMGAVINQAPRLFNGIVAQVPFVD
VVTTMLDESIPLTTGEYDEWGNPNEQAYYDYILQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLRELKTDDR
QLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILALAE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=694, Percent_Identity=25.3602305475504, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI284172438, Length=574, Percent_Identity=26.6550522648084, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI284172431, Length=574, Percent_Identity=26.6550522648084, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI284172420, Length=574, Percent_Identity=26.6550522648084, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI284172413, Length=574, Percent_Identity=26.6550522648084, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI70778815, Length=574, Percent_Identity=26.6550522648084, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI108860686, Length=221, Percent_Identity=36.1990950226244, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI108860692, Length=212, Percent_Identity=36.3207547169811, Blast_Score=145, Evalue=2e-34,
Organism=Escherichia coli, GI1788150, Length=676, Percent_Identity=65.2366863905325, Blast_Score=939, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=696, Percent_Identity=25.4310344827586, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI221510989, Length=688, Percent_Identity=25.7267441860465, Blast_Score=174, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78374; Mature: 78374

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPPKAEKRPYPITTHGDTRVDDYYWLRDDERADPQVLDYLQAENAFTDAVLKPQQALR
CCCCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHH
ETLYEEMVARIPQQEHSVPYVRHGYRYQTRFEPGNEYAIYVRQPQAESEHWDILIDGNQR
HHHHHHHHHHCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCC
AEQREFYTLGGLEVSPDNQKLAVAEDFLSRRQYDIRFKNLSDDSWTDEVLENTSGSFEWA
CCCCCEEEECCEEECCCCCEEHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCEEEC
NDSATVYYVRKHAKTLLPYQVYRHVVGTDPQLDELIYEEKDDTFYVGLEKTTSDRFILIH
CCCEEEEEEEHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCEEEEE
LSSTTTSEILLLDADRADSKPQMFVPRRKDHEYGIDHYHQHFYIRSNKDGKNFGLYQSDQ
ECCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
ADEAQWQTLIAPRIEVMLEGFSLFRDWLVVEERSEGLTQLRQIHWQSGEVKRIAFDDPTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCEEEEEECCCCE
TTWLAYNPEPETELLRYGYSSMTTPTTLYELNLDSGERVMLKQQEVKNFTPENYRSERVW
EEEEEECCCCHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEHHHHHCCCCCCCCCCEEE
VKARDGVEVPVSLVYRHDKFTRGTNPLMVYGYGSYGSSMDPAFSASRLSLLDRGFVFVLA
EEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEE
HIRGGGELGQLWYEDGKLFKKQNTFNDFIDVTEALIAQGYGDAKRVFAMGGSAGGLLMGA
ECCCCCHHHHHEECCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
VINQAPRLFNGIVAQVPFVDVVTTMLDESIPLTTGEYDEWGNPNEQAYYDYILQYSPYDQ
HHHHCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHH
VKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLRELKTDDRQLLLYTDMDSGHGGKSGRFK
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCC
AYEDIALEYAFILALAE
HHHHHHHEEEEEEEECC
>Mature Secondary Structure
MMTPPKAEKRPYPITTHGDTRVDDYYWLRDDERADPQVLDYLQAENAFTDAVLKPQQALR
CCCCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHH
ETLYEEMVARIPQQEHSVPYVRHGYRYQTRFEPGNEYAIYVRQPQAESEHWDILIDGNQR
HHHHHHHHHHCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCC
AEQREFYTLGGLEVSPDNQKLAVAEDFLSRRQYDIRFKNLSDDSWTDEVLENTSGSFEWA
CCCCCEEEECCEEECCCCCEEHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCEEEC
NDSATVYYVRKHAKTLLPYQVYRHVVGTDPQLDELIYEEKDDTFYVGLEKTTSDRFILIH
CCCEEEEEEEHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCEEEEE
LSSTTTSEILLLDADRADSKPQMFVPRRKDHEYGIDHYHQHFYIRSNKDGKNFGLYQSDQ
ECCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
ADEAQWQTLIAPRIEVMLEGFSLFRDWLVVEERSEGLTQLRQIHWQSGEVKRIAFDDPTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCEEEEEECCCCE
TTWLAYNPEPETELLRYGYSSMTTPTTLYELNLDSGERVMLKQQEVKNFTPENYRSERVW
EEEEEECCCCHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEHHHHHCCCCCCCCCCEEE
VKARDGVEVPVSLVYRHDKFTRGTNPLMVYGYGSYGSSMDPAFSASRLSLLDRGFVFVLA
EEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEE
HIRGGGELGQLWYEDGKLFKKQNTFNDFIDVTEALIAQGYGDAKRVFAMGGSAGGLLMGA
ECCCCCHHHHHEECCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
VINQAPRLFNGIVAQVPFVDVVTTMLDESIPLTTGEYDEWGNPNEQAYYDYILQYSPYDQ
HHHHCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHH
VKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLRELKTDDRQLLLYTDMDSGHGGKSGRFK
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCC
AYEDIALEYAFILALAE
HHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]